ADRB1

Summary Top Help

Gene Description:

adrenergic receptor, beta 1; adrenergic, beta-1-, receptor

Synonyms:

RATB1AR, ADRB1, ADRB1R, RHR, beta-AR, Adrb1, Adrb-1, B1AR, BETA1AR

Orthologs:

Human ADRB1 (protein-coding), Mouse Adrb1 (protein-coding), Rat Adrb1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Rat: 2

Linkage Regions: 2 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Iddm9	Rat	chr1:247322146..266002939	18.68	162
Klotting Iddm5r	Rat	chr1:247322146..266002939	18.68	162	1 Suggestive for backcross, 2 no lod score

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr10:115803806..115806667 (2.86 kb) View in Genome Browser

(Mouse) NCBIM37 - chr19:56796862..56799352 (2.49 kb) View in Genome Browser

(Rat) RGSC3.4 - chr1:263025655..263027055 (1.40 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for ADRB1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for ADRB1:

The ADRB1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.

The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.

Interactor	Interactor	Sources	Classification	Pubmed IDs
ADRB1	GIPC1	HPRD, IntAct, BioGRID	empirical	12724327 16316992
ADRB1	GPRASP2	HPRD	empirical	15086532
ADRB1	ADRA2A	HPRD	empirical	12529373
ADRB1	DLG1	HPRD, IntAct	empirical	16316992
ADRB1	DLG4	HPRD, IntAct, BioGRID	empirical	10995758 16316992
ADRB1	MAGI3	HPRD, IntAct	empirical	16316992
ADRB1	GRB2	HPRD	empirical	9843378
ADRB1	ARRB1	HPRD, BioGRID	empirical	10862778
ADRB1	NOS1	HPRD	empirical	12184796
ADRB1	PDE4D	MINT	empirical	18188154
ADRB1	PRKACA	MINT	empirical	18188154
ADRB1	GOPC	HPRD, IntAct	empirical	16316992
ADRB1	SH3GL2	HPRD	empirical	10535961
ADRB1	SH3GL3	HPRD	empirical	10535961
ADRB1	MAGI1	IntAct	empirical	16316992
ADRB1	DLGAP2	HPRD	empirical	11700307
ADRB1	GPRASP1	HPRD, IntAct	empirical	15452121 15086532
ADRB1	MAGI2	HPRD, MINT, IntAct	empirical	11526121 16316992

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 6

Biocarta: None available

Reactome: 7

NCI-Nature Pathway Interaction Database: None available

Gene Ontology: 45

Positive regulation of heart rate by epinephrine-norepinephrine	GO:0001996
Diet induced thermogenesis	GO:0002024
Vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	GO:0002025
Positive regulation of the force of heart contraction by norepinephrine	GO:0003061
Positive regulation of systemic arterial blood pressure	GO:0003084
Signal transducer activity	GO:0004871
Receptor activity	GO:0004872
G-protein coupled receptor activity	GO:0004930
Beta-adrenergic receptor activity	GO:0004939
Beta1-adrenergic receptor activity	GO:0004940
Protein binding	GO:0005515
Membrane fraction	GO:0005624
Nucleus	GO:0005634
Cytoplasm	GO:0005737
Microsome	GO:0005792
Plasma membrane	GO:0005886
Integral to plasma membrane	GO:0005887
Glycogen catabolic process	GO:0005980
Apoptotic process	GO:0006915
Activation of adenylate cyclase activity by G-protein signaling pathway	GO:0007189
Activation of adenylate cyclase activity	GO:0007190
Rho protein signal transduction	GO:0007266
Aging	GO:0007568
Memory	GO:0007613
Drug binding	GO:0008144
Response to cold	GO:0009409
Sensory perception of pain	GO:0019233
PDZ domain binding	GO:0030165
Positive regulation of cAMP biosynthetic process	GO:0030819
Heat generation	GO:0031649
Alpha-2A adrenergic receptor binding	GO:0031694
Dopamine binding	GO:0035240
Negative regulation of urine volume	GO:0035811
Negative regulation of multicellular organism growth	GO:0040015
Wound healing	GO:0042060
Fear response	GO:0042596
Negative regulation of smooth muscle contraction	GO:0045986
Positive regulation of saliva secretion	GO:0046878
Protein heterodimerization activity	GO:0046982
Brown fat cell differentiation	GO:0050873
Epinephrine binding	GO:0051379
Norepinephrine binding	GO:0051380
Positive regulation of calcium ion transport via voltage-gated calcium channel activity	GO:0051929
Regulation of inhibitory postsynaptic membrane potential	GO:0060080
Positive regulation of cell growth involved in cardiac muscle cell development	GO:0061051

Publications from PubMed Top Help

Type 1 Diabetes Publications: 1

Publications: 445

A common β1-adrenergic receptor polymorphism predicts favorable response to rate-control therapy in atrial fibrillation.
Parvez B, Chopra N, Rowan S, Vaglio JC, Muhammad R, Roden DM, Darbar D
J Am Coll Cardiol. 2012
PubMed ID: 22192668
Analysis of beta1 and beta2-adrenergic receptors polymorphism in patients with apical ballooning cardiomyopathy.
Vriz O, Minisini R, Citro R, Guerra V, Zito C, De Luca G, Pavan D, Pirisi M, Limongelli G, Bossone E
Acta Cardiol. 2011
PubMed ID: 22299391
β₁-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β₃-adrenergic receptor-knockout mice via nonshivering thermogenesis.
Mattsson CL, Csikasz RI, Chernogubova E, Yamamoto DL, Hogberg HT, Amri EZ, Hutchinson DS, Bengtsson T
Am J Physiol Endocrinol Metab. 2011
PubMed ID: 21878665
Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling.
Schutsky K, Ouyang M, Castelino CB, Zhang L, Thomas SA
J Neurosci. 2011
PubMed ID: 21976502
Methylation of adrenergic beta1 receptor is a potential epigenetic mechanism controlling antihypertensive response to metoprolol.
Jiang Q, Yuan H, Xing X, Liu J, Huang Z, Du X
Indian J Biochem Biophys. 2011
PubMed ID: 22165287
Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.
Zhao M, Fajardo G, Urashima T, Spin JM, Poorfarahani S, Rajagopalan V, Huynh D, Connolly A, Quertermous T, Bernstein D
Am J Physiol Heart Circ Physiol. 2011
PubMed ID: 21705675
Confinement of β(1)- and β(2)-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae.
Valentine CD, Haggie PM
Mol Biol Cell. 2011
PubMed ID: 21680711
The Arg389Gly β1-adrenoceptor gene polymorphism influences the acute effects of β-adrenoceptor blockade on contractility in the human heart.
Huntgeburth M, La Rosée K, ten Freyhaus H, Böhm M, Schnabel P, Hellmich M, Rosenkranz S
Clin Res Cardiol. 2011
PubMed ID: 21311897
[Expression and significance of β adrenergic receptors in a model of left ventricular mechanical unloading].
Gao X, Zhang RC, Zhu RJ, Liang ZQ, Wang JW, Meng XH, Sun F, Wei L
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011
PubMed ID: 21787468
Renin expression in large renal vessels during fetal development depends on functional beta1/beta2-adrenergic receptors.
Neubauer B, Machura K, Schnermann J, Wagner C
Am J Physiol Renal Physiol. 2011
PubMed ID: 21389089
Polymorphisms of the beta adrenergic receptor predict left ventricular remodeling following acute myocardial infarction.
McLean RC, Hirsch GA, Becker LC, Kasch-Semenza L, Gerstenblith G, Schulman SP
Cardiovasc Drugs Ther. 2011
PubMed ID: 21626217
Carvedilol pharmacokinetics and pharmacodynamics in relation to CYP2D6 and ADRB pharmacogenetics.
Sehrt D, Meineke I, Tzvetkov M, Gültepe S, Brockmöller J
Pharmacogenomics. 2011
PubMed ID: 21599570
Haplotype structures of common variants of CYP2C8, CYP2C9, and ADRB1 genes in a South Indian population.
Arun Kumar AS, Chakradhara Rao US, Umamaheswaran G, Ramu P, Kesavan R, Shewade DG, Balachandar J, Adithan C
Genet Test Mol Biomarkers. 2011
PubMed ID: 21375401
Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptor.
Zuckerman DM, Hicks SW, Charron G, Hang HC, Machamer CE
J Biol Chem. 2011
PubMed ID: 21464135
Long-term active immunization with a synthetic peptide corresponding to the second extracellular loop of β1-adrenoceptor induces both morphological and functional cardiomyopathic changes in rats.
Zuo L, Bao H, Tian J, Wang X, Zhang S, He Z, Yan L, Zhao R, Ma XL, Liu H
Int J Cardiol. 2011
PubMed ID: 20096470
Stress-induced epinephrine levels compromise murine dermal fibroblast activity through β-adrenoceptors.
Romana-Souza B, Otranto M, Almeida TF, Porto LC, Monte-Alto-Costa A
Exp Dermatol. 2011
PubMed ID: 21366703
Effect of the ADRB1 1165C>G and 145A>G polymorphisms on hemodynamic response during dobutamine stress echocardiography.
Banaś A, Płońska E, Kurzawski M, Gornik W, Droździk M
Eur J Clin Pharmacol. 2011
PubMed ID: 21305273
Receptor specific crosstalk and modulation of signaling upon heterodimerization between β1-adrenergic receptor and somatostatin receptor-5.
Somvanshi RK, War SA, Chaudhari N, Qiu X, Kumar U
Cell Signal. 2011
PubMed ID: 21238583
Role of β-adrenoceptors in glucose uptake in astrocytes using β-adrenoceptor knockout mice.
Catus SL, Gibbs ME, Sato M, Summers RJ, Hutchinson DS
Br J Pharmacol. 2011
PubMed ID: 21138422
Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo.
Pulinilkunnil T, He H, Kong D, Asakura K, Peroni OD, Lee A, Kahn BB
J Biol Chem. 2011
PubMed ID: 21209093
Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation.
Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, Hu Y, Agarwal R, Yu S, Jiang H, Steinberg SF, Blaner WS, Koch WJ, Goldberg IJ
Am J Physiol Endocrinol Metab. 2011
PubMed ID: 21139071
Transient {beta}2-adrenoceptor activation confers pregnancy loss by disrupting embryo spacing at implantation.
Chen Q, Zhang Y, Peng H, Lei L, Kuang H, Zhang L, Ning L, Cao Y, Duan E
J Biol Chem. 2011
PubMed ID: 21148315
Human atrial β(1L)-adrenoceptor but not β₃-adrenoceptor activation increases force and Ca(2+) current at physiological temperature.
Christ T, Molenaar P, Klenowski PM, Ravens U, Kaumann AJ
Br J Pharmacol. 2011
PubMed ID: 20726983
FRET-based direct detection of dynamic protein kinase A activity on the sarcoplasmic reticulum in cardiomyocytes.
Liu S, Zhang J, Xiang YK
Biochem Biophys Res Commun. 2011
PubMed ID: 21130738
β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.
Zhang W, Yano N, Deng M, Mao Q, Shaw SK, Tseng YT
PLoS One. 2011
PubMed ID: 22028912
Increased tumor necrosis factor-α, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the β₁-adrenergic receptor knockout mouse.
Panjala SR, Jiang Y, Kern TS, Thomas SA, Steinle JJ
Mol Vis. 2011
PubMed ID: 21850156
Regulation of catecholamine-synthesising enzymes and beta-adrenoceptors gene expression in ventricles of stressed rats.
Spasojevic N, Gavrilovic L, Dronjak S
Physiol Res. 2011
PubMed ID: 21777029
Clustering heart rate dynamics is associated with β-adrenergic receptor polymorphisms: analysis by information-based similarity index.
Yang AC, Tsai SJ, Hong CJ, Wang C, Chen TJ, Liou YJ, Peng CK
PLoS One. 2011
PubMed ID: 21573230
β(1)-Adrenergic receptor gene polymorphisms and the acute response to atenolol in healthy young Japanese subjects.
Sasaguri T, Shiraishi F, Yoshihara T, Takahashi-Yanaga F, Morimoto S
J Pharmacol Sci. 2011
PubMed ID: 21422729
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
β1, β2, and β3 adrenoceptors and Na+/H+ exchanger regulatory factor 1 expression in human bronchi and their modifications in cystic fibrosis.
Bossard F, Silantieff E, Lavazais-Blancou E, Robay A, Sagan C, Rozec B, Gauthier C
Am J Respir Cell Mol Biol. 2011
PubMed ID: 20203292
Association of Single-Nucleotide Polymorphisms From 17 Candidate Genes With Baseline Symptom-Limited Exercise Test Duration and Decrease in Duration Over 20 Years: The Coronary Artery Risk Development in Young Adults (CARDIA) Fitness Study.
Sarzynski MA, Rankinen T, Sternfeld B, Grove ML, Fornage M, Jacobs DR, Sidney S, Bouchard C
Circ Cardiovasc Genet. 2010
PubMed ID: 20952631
Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma.
Gao Y, Sakurai M, Takeda H, Higashide T, Kawase K, Sugiyama K
Ophthalmology. 2010
PubMed ID: 20705341
Polymorphisms of adrenergic cardiovascular control genes are associated with adolescent chronic fatigue syndrome.
Sommerfeldt L, Portilla H, Jacobsen L, Gjerstad J, Wyller VB
Acta Paediatr. 2010
PubMed ID: 21059181
Genetic variants of connexin37 are associated with carotid intima-medial thickness and future onset of ischemic stroke.
Leu HB, Chung CM, Chuang SY, Bai CH, Chen JR, Chen JW, Pan WH
Atherosclerosis. 2010
PubMed ID: 21044781
The Arg16Gly-β(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure.
Leineweber K, Frey UH, Tenderich G, Toliat MR, Zittermann A, Nürnberg P, Körfer R, Siffert W, Heusch G
Naunyn Schmiedebergs Arch Pharmacol. 2010
PubMed ID: 20803192
Role of beta-adrenergic receptors in the ventromedial prefrontal cortex during contextual fear extinction in rats.
Do-Monte FH, Kincheski GC, Pavesi E, Sordi R, Assreuy J, Carobrez AP
Neurobiol Learn Mem. 2010
PubMed ID: 20667477
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
A candidate gene study of obstructive sleep apnea in European Americans and African Americans.
Larkin EK, Patel SR, Goodloe RJ, Li Y, Zhu X, Gray-McGuire C, Adams MD, Redline S
Am J Respir Crit Care Med. 2010
PubMed ID: 20538960
Human beta1-adrenergic receptor is subject to constitutive and regulated N-terminal cleavage.
Hakalahti AE, Vierimaa MM, Lilja MK, Kumpula EP, Tuusa JT, Petäjä-Repo UE
J Biol Chem. 2010
PubMed ID: 20587416
Functional effects of beta(1)-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without beta-blocker administration.
Kindermann M, Seeland U, Ruhnke P, Böhm M, Maack C
Clin Res Cardiol. 2010
PubMed ID: 20821015
Beta2-adrenoceptor gene variant Arg16Gly is associated with idiopathic ventricular outflow-tract tachycardia.
Ran YQ, Li N, Yang Y, Chen JZ, Feng L, Zhang S, Pu JL
Chin Med J (Engl). 2010
PubMed ID: 21034538
Beta-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.
Kelsey RM, Alpert BS, Dahmer MK, Krushkal J, Quasney MW
Psychophysiology. 2010
PubMed ID: 20374546
beta2- but not beta1-adrenoceptor activation modulates intracellular oxygen availability.
Li J, Yan B, Huo Z, Liu Y, Xu J, Sun Y, Liu Y, Liang D, Peng L, Zhang Y, Zhou ZN, Shi J, Cui J, Chen YH
J Physiol. 2010
PubMed ID: 20547682
Relation of ADRB1, CYP2D6, and UGT1A1 polymorphisms with dose of, and response to, carvedilol or metoprolol therapy in patients with chronic heart failure.
Baudhuin LM, Miller WL, Train L, Bryant S, Hartman KA, Phelps M, Larock M, Jaffe AS
Am J Cardiol. 2010
PubMed ID: 20643254
{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways.
Wang W, Zhang H, Gao H, Kubo H, Berretta RM, Chen X, Houser SR
Am J Physiol Heart Circ Physiol. 2010
PubMed ID: 20495143
Post-treatment with selective β1 adrenoceptor antagonists provides neuroprotection against transient focal ischemia in rats.
Goyagi T, Horiguchi T, Nishikawa T, Tobe Y
Brain Res. 2010
PubMed ID: 20451506
Polymorphic variants of beta1 adrenergic receptor gene (Ser49Gly & Arg389Gly) in healthy Tamilian volunteers.
Ramu P, Mahesh Kumar KN, Shewade DG, Swaminathan RP, Dutta TK, Balachander J, Adithan C
Indian J Med Res. 2010
PubMed ID: 20693591
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
Ruaño G, Thompson PD, Kane JP, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH
Pharmacogenomics. 2010
PubMed ID: 20602615
Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB
Am J Med Genet B Neuropsychiatr Genet. 2010
PubMed ID: 20468064
Role of beta1-adrenoceptor in increased lipolysis in cancer cachexia.
Cao DX, Wu GH, Yang ZA, Zhang B, Jiang Y, Han YS, He GD, Zhuang QL, Wang YF, Huang ZL, Xi QL
Cancer Sci. 2010
PubMed ID: 20426789
Rab1 GTPase promotes expression of beta-adrenergic receptors in rat pulmonary microvascular endothelial cells.
Li Y, Wang G, Lin K, Yin H, Zhou C, Liu T, Wu G, Qian G
Int J Biochem Cell Biol. 2010
PubMed ID: 20417717
beta-Adrenergic activation of electrogenic K+ and Cl- secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways.
Halm ST, Zhang J, Halm DR
Am J Physiol Gastrointest Liver Physiol. 2010
PubMed ID: 20413718
Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope.
Sorrentino S, Forleo C, Iacoviello M, Guida P, D'Andria V, Favale S
Auton Neurosci. 2010
PubMed ID: 20129829
Impact of genomic polymorphism on arterial hypertension after aortic coarctation repair.
Hager A, Bildau J, Kreuder J, Kaemmerer H, Hess J
Int J Cardiol. 2010
PubMed ID: 20537417
Common genetic variation of beta1- and beta2-adrenergic receptor and response to four classes of antihypertensive treatment.
Suonsyrjä T, Donner K, Hannila-Handelberg T, Fodstad H, Kontula K, Hiltunen TP
Pharmacogenet Genomics. 2010
PubMed ID: 20300048
Genetic polymorphisms of the adrenergic system and implantable cardioverter-defibrillator therapies in patients with heart failure.
Chemello D, Rohde LE, Santos KG, Silvello D, Goldraich L, Pimentel M, Rosa PR, Zimerman L, Clausell N
Europace. 2010
PubMed ID: 20185488
Association of ADRB1 gene polymorphism with atrial fibrillation.
Nicoulina S, Shulman V, Shesternya P, Chernova A, Salmina A, Issachenko O, Maksimov V, Voevoda M
Genet Test Mol Biomarkers. 2010
PubMed ID: 20384459
beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling.
Gao MH, Tang T, Miyanohara A, Feramisco JR, Hammond HK
Cell Signal. 2010
PubMed ID: 19932173
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J
Science. 2010
PubMed ID: 20185685
Can we predict top-level sports performance in power vs endurance events? A genetic approach.
Buxens A, Ruiz JR, Arteta D, Artieda M, Santiago C, González-Freire M, Martínez A, Tejedor D, Lao JI, Gómez-Gallego F, Lucia A
Scand J Med Sci Sports. 2010
PubMed ID: 20459474
Relationship between beta1-adrenergic receptor polymorphisms and cardiovascular disease in patients with diabetic nephropathy.
Poon PY, Szeto CC, Kwan BC, Chow KM, Li PK
Nephrology (Carlton). 2010
PubMed ID: 20470286
Targeting receptor antibodies in immune cardiomyopathy.
Jahns R, Schlipp A, Boivin V, Lohse MJ
Semin Thromb Hemost. 2010
PubMed ID: 20414837
Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension.
Filigheddu F, Argiolas G, Degortes S, Zaninello R, Frau F, Pitzoi S, Bulla E, Bulla P, Troffa C, Glorioso N
Pharmacogenomics. 2010
PubMed ID: 20235788
Pro-inflammatory responses in human monocytes are beta1-adrenergic receptor subtype dependent.
Grisanti LA, Evanson J, Marchus E, Jorissen H, Woster AP, DeKrey W, Sauter ER, Combs CK, Porter JE
Mol Immunol. 2010
PubMed ID: 20116105
Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database.
Kitsios GD, Zintzaras E
Am J Hypertens. 2010
PubMed ID: 20044737
Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition.
Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB
Cardiovasc Res. 2010
PubMed ID: 19900965
Role of beta-adrenergic receptor gene polymorphisms in the long-term effects of beta-blockade with carvedilol in patients with chronic heart failure.
Metra M, Covolo L, Pezzali N, Zacà V, Bugatti S, Lombardi C, Bettari L, Romeo A, Gelatti U, Giubbini R, Donato F, Dei Cas L
Cardiovasc Drugs Ther. 2010
PubMed ID: 20352314
beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes.
Mani SK, Egan EA, Addy BK, Grimm M, Kasiganesan H, Thiyagarajan T, Renaud L, Brown JH, Kern CB, Menick DR
J Mol Cell Cardiol. 2010
PubMed ID: 19945464
Age-related increase of beta1-adrenergic receptor gene expression in rat liver: a potential mechanism contributing to increased beta-adrenergic receptor density and responsiveness during aging.
Jin W
J Recept Signal Transduct Res. 2010
PubMed ID: 19883205
[Impact of Gly389Arg beta1-adrenoceptor polymorphism on the risk of chronic heart failure, the nature of its course, and on the efficiency of its treatment with carvedilol].
Tepliakov AT, Shilov SN, Berezikova EN, Torim IuIu, Efremov AV, Safronov ID, Maianskaia SD, Popova AA, Voronina EN, Karpov RS
Ter Arkh. 2010
PubMed ID: 21516734
Intense exercise training induces adaptation in expression and responsiveness of cardiac β-adrenoceptors in diabetic rats.
Lahaye Sle D, Gratas-Delamarche A, Malardé L, Vincent S, Zguira MS, Morel SL, Delamarche P, Zouhal H, Carré F, Bekono FR
Cardiovasc Diabetol. 2010
PubMed ID: 21054861
Polymorphisms in α- and β-Adrenergic Receptor Genes, Hypertension, and Obstructive Sleep Apnea: The Skaraborg Sleep Study.
Bengtsson Boström K, Hedner J, Grote L, Melander O, von Wowern F, Råstam L, Groop L, Lindblad U
Int J Hypertens. 2010
PubMed ID: 20948559
[Genetic predisposition to development of atrial fibrillation in patients with hypertensive disease].

Kardiologiia. 2010
PubMed ID: 20831043
Association of the beta-1 adrenergic receptor carboxyl terminal variants with left ventricular hypertrophy among diabetic and non-diabetic survivors of acute myocardial infarction.
Hakalahti AE, Tapanainen JM, Junttila JM, Kaikkonen KS, Huikuri HV, Petäjä-Repo UE
Cardiovasc Diabetol. 2010
PubMed ID: 20731869
Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation.
Nia AM, Caglayan E, Gassanov N, Zimmermann T, Aslan O, Hellmich M, Duru F, Erdmann E, Rosenkranz S, Er F
PLoS One. 2010
PubMed ID: 20625396
A Pilot Study of the Pharmacodynamic Impact of SSRI Drug Selection and Beta-1 Receptor Genotype (ADRB1) on Cardiac Vital Signs in Depressed Patients: A Novel Pharmacogenetic Approach.
Thomas KL, Ellingrod VL, Bishop JR, Keiser MJ
Psychopharmacol Bull. 2010
PubMed ID: 20581797
Total beta-adrenoceptor deficiency results in cardiac hypotrophy and negative inotropy.
Lee S, Grafweg S, Schneider T, Jimenez M, Giacobino JP, Ghanem A, Tiemann K, Bloch W, Müller-Ehmsen J, Schwinger RH, Brixius K
Physiol Res. 2010
PubMed ID: 20406048
[Myocardial hypertrophy in patients with hypertensive disease: the role of genetic polymorphism of beta-adrenoreactive structures]

Kardiologiia. 2010
PubMed ID: 20144152
Polymorphisms of beta-adrenoceptor and natriuretic peptide receptor genes influence the susceptibility to and the severity of idiopathic dilated cardiomyopathy in a Chinese cohort.
Wang L, Lu L, Zhang F, Chen Q, Shen W
J Card Fail. 2010
PubMed ID: 20123316
L41Q polymorphism of the G protein coupled receptor kinase 5 is associated with left ventricular apical ballooning syndrome.
Spinelli L, Trimarco V, Di Marino S, Marino M, Iaccarino G, Trimarco B
Eur J Heart Fail. 2010
PubMed ID: 20023040
The beta1-adrenergic receptor mediates extracellular signal-regulated kinase activation via Galphas.
Zheng J, Shen H, Xiong Y, Yang X, He J
Amino Acids. 2010
PubMed ID: 19037712
Transferability of thermostabilizing mutations between beta-adrenergic receptors.
Serrano-Vega MJ, Tate CG
Mol Membr Biol. 2009
PubMed ID: 19883298
Genetic factors are relevant and independent determinants of antihypertensive drug effects in a multiracial population.
van Rijn-Bikker PC, Mairuhu G, van Montfrans GA, Sijbrands EJ, Zwinderman AH, Guchelaar HJ, Koopmans RP
Am J Hypertens. 2009
PubMed ID: 19779464
Beta-adrenergic stimulation and myocardial function in the failing heart.
El-Armouche A, Eschenhagen T
Heart Fail Rev. 2009
PubMed ID: 19110970
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.
Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV
J Clin Invest. 2009
PubMed ID: 19855129
Differential contribution of beta-adrenergic receptors expressed on radiosensitive versus radioresistant cells to protection against inflammation and mortality in murine endotoxemia.
Walker-Brown J, Roberts MR
Shock. 2009
PubMed ID: 19333138
[The association between polymorphism of beta(1)-adrenoceptor genes and cardiovascular complication in obstructive sleep apnea-hypopnea syndrome patients in Han population]
Chen XY, Wang B, Liu ZL, Wang Q
Zhonghua Jie He He Hu Xi Za Zhi. 2009
PubMed ID: 20079238
GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.
Kurnik D, Cunningham AJ, Sofowora GG, Kohli U, Li C, Friedman EA, Muszkat M, Menon UB, Wood AJ, Stein CM
Pharmacogenomics. 2009
PubMed ID: 19842931
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction.
Yoo B, Lemaire A, Mangmool S, Wolf MJ, Curcio A, Mao L, Rockman HA
Am J Physiol Heart Circ Physiol. 2009
PubMed ID: 19633206
Therapeutic efficacy of a combination of a beta1-adrenoreceptor (AR) blocker and beta2-AR agonist in a rat model of postmyocardial infarction dilated heart failure exceeds that of a beta1-AR blocker plus angiotensin-converting enzyme inhibitor.
Ahmet I, Morrell C, Lakatta EG, Talan MI
J Pharmacol Exp Ther. 2009
PubMed ID: 19587314
Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis.
Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Brophy VH, O'Connor DT, for the AASK Co-Investigators
Nephrol Dial Transplant. 2009
PubMed ID: 19745105
[Dynamic changes of alpha-AR, beta1-AR and beta2-AR expression during hepatic fibrogenesis].
Liu N, Zhang XL, Liang CD, Yao DM, Liu L, Zhao DQ, Tian XP
Zhonghua Gan Zang Bing Za Zhi. 2009
PubMed ID: 19785950
Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y
Int J Mol Med. 2009
PubMed ID: 19578796
Effect of 393T>C polymorphism of GNAS1 gene on dobutamine response in Chinese healthy subjects.
Mao YM, Liu ZQ, Chen BL, Guo D, Han CT, Yang LJ, Wang SY, Fan L, Zhou HH
J Clin Pharmacol. 2009
PubMed ID: 19542315
Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.
Kobayashi H, Ogawa K, Yao R, Lichtarge O, Bouvier M
Traffic. 2009
PubMed ID: 19515093
Clinical and genetic modifiers of long-term survival in heart failure.
Cresci S, Kelly RJ, Cappola TP, Diwan A, Dries D, Kardia SL, Dorn GW
J Am Coll Cardiol. 2009
PubMed ID: 19628119
beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling.
Tilley DG, Kim IM, Patel PA, Violin JD, Rockman HA
J Biol Chem. 2009
PubMed ID: 19509284
beta1-Adrenoceptor distribution in the rat brain: an immunohistochemical study.
Paschalis A, Churchill L, Marina N, Kasymov V, Gourine A, Ackland G
Neurosci Lett. 2009
PubMed ID: 19442879
Diverse evolutionary histories for beta-adrenoreceptor genes in humans.
Cagliani R, Fumagalli M, Pozzoli U, Riva S, Comi GP, Torri F, Macciardi F, Bresolin N, Sironi M
Am J Hum Genet. 2009
PubMed ID: 19576569
Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance.
Santiago C, Ruiz JR, Buxens A, Artieda M, Arteta D, Gonzalez-Freire M, Rodríguez-Romo G, Altmäe S, Lao JI, Gómez-Gallego F, Lucia A
Br J Sports Med. 2009
PubMed ID: 19553224
Polymorphisms of adrenoceptors are not associated with an increased risk of adverse event in heart failure: a MERIT-HF substudy.
Savva J, Maqbool A, White HL, Galloway SL, Yuldasheva NY, Ball SG, West RM, De Boer RA, Van Veldhuisen DJ, Balmforth AJ, Merit-HF Study Group
J Card Fail. 2009
PubMed ID: 19477404
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
Nogueiras R, Pérez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, López M, Woods SC, DiMarchi R, Diéguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH
J Neurosci. 2009
PubMed ID: 19420258
Genetic variants of beta(1)-adrenoceptor gene polymorphisms (Ser49Gly and Arg389Gly) and essential hypertension in a south Indian Tamil population.
Ramu P, Rajan S, Shewade DG, Swaminathan RP, Dutta TK, Balachander J, Adithan C
Clin Exp Pharmacol Physiol. 2009
PubMed ID: 19673943
[Synthesis and properties of a new conformational antigen modeling an extracellular region of beta(1)-adrenoreceptor]
Sidorova MV, Pal'keeva ME, Molokoedov AS, Az'muko AA, Sekridova AV, Ovchinnikov MV, Levashov PA, Afanas'eva OI, Berestetskaia YV, Afanas'eva MI, Razova OA, Bespalova ZhD, Pokrovskiĭ SN
Bioorg Khim. 2009
PubMed ID: 19621046
Calmodulin kinase II is required for fight or flight sinoatrial node physiology.
Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19276108
Testosterone-augmented contractile responses to alpha1- and beta1-adrenoceptor stimulation are associated with increased activities of RyR, SERCA, and NCX in the heart.
Tsang S, Wong SS, Wu S, Kravtsov GM, Wong TM
Am J Physiol Cell Physiol. 2009
PubMed ID: 19336623
Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw.
Marotta DM, Costa R, Motta EM, Fernandes ES, Medeiros R, Quintão NL, Campos MM, Calixto JB
Biochem Pharmacol. 2009
PubMed ID: 19283893
Evidence for beta1-adrenergic receptor involvement in amygdalar corticotropin-releasing factor gene expression: implications for cocaine withdrawal.
Rudoy CA, Reyes AR, Van Bockstaele EJ
Neuropsychopharmacology. 2009
PubMed ID: 18596687
Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction.
Soto D, De Arcangelis V, Zhang J, Xiang Y
Circ Res. 2009
PubMed ID: 19213958
Polymorphisms of the beta-1 and beta-2 adrenergic receptors in Polish patients with idiopathic dilated cardiomyopathy.
Paczkowska A, Szperl M, Małek Ł, Mazurkiewicz Ł, Skóra E, Grzybowski J, Roszczynko M, Bilińska Z, Tesson F, Ruzyłło W
Kardiol Pol. 2009
PubMed ID: 19378229
beta-1 and beta-2, but not alpha-1 and alpha-2, adrenoceptor blockade delays rat cutaneous wound healing.
Romana-Souza B, Santos JS, Monte-Alto-Costa A
Wound Repair Regen. 2009
PubMed ID: 19320892
Expressions of cardiac sympathetic norepinephrine transporter and beta1-adrenergic receptor decreased in aged rats.
Li H, Ma XQ, Ye F, Zhang J, Zhou X, Wang ZH, Li YM, Zhang GY
J Zhejiang Univ Sci B. 2009
PubMed ID: 19283875
The impact of alpha1-adrenoceptors up-regulation accompanied by the impairment of beta-adrenergic vasodilatation in hypertension.
Oliver E, Martí D, Montó F, Flacco N, Moreno L, Barettino D, Ivorra MD, D'Ocon P
J Pharmacol Exp Ther. 2009
PubMed ID: 19060223
Adrenergic receptor polymorphisms in patients with stress (tako-tsubo) cardiomyopathy.
Sharkey SW, Maron BJ, Nelson P, Parpart M, Maron MS, Bristow MR
J Cardiol. 2009
PubMed ID: 19167638
Normotensive sodium loading in normal man: regulation of renin secretion during beta-receptor blockade.
Mølstrøm S, Larsen NH, Simonsen JA, Washington R, Bie P
Am J Physiol Regul Integr Comp Physiol. 2009
PubMed ID: 19073901
The effects of aerobic fitness and beta1-adrenergic receptor blockade on cardiac work during dynamic exercise.
Hawkins MN, Barnes Q, Purkayastha S, Eubank W, Ogoh S, Raven PB
J Appl Physiol. 2009
PubMed ID: 19036891
Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.
Ruaño G, Bernene J, Windemuth A, Bower B, Wencker D, Seip RL, Kocherla M, Holford TR, Petit WA, Hanks S
Clin Chim Acta. 2009
PubMed ID: 18996102
Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction.
Lewin G, Matus M, Basu A, Frebel K, Rohsbach SP, Safronenko A, Seidl MD, Stümpel F, Buchwalow I, König S, Engelhardt S, Lohse MJ, Schmitz W, Müller FU
Circulation. 2009
PubMed ID: 19103994
Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
Holmes MV, Shah T, Vickery C, Smeeth L, Hingorani AD, Casas JP
PLoS One. 2009
PubMed ID: 19956635
[Ser49gly polymorphism as predictor of development of hereditary sick sinus node syndrome]
Nikulina SIu, Shul'man VA, Chernova AA, Voevoda MI, Maksimov VN, Kazarinova IuL
Kardiologiia. 2009
PubMed ID: 19845516
Polymorphisms of the beta1-adrenergic receptor gene are associated with essential hypertension in Chinese.
Peng Y, Xue H, Luo L, Yao W, Li R
Clin Chem Lab Med. 2009
PubMed ID: 19743955
Association of beta-1 and beta-2 adrenergic receptor gene polymorphisms with myocardial infarction.
Yilmaz A, Kaya MG, Merdanoglu U, Ergun MA, Cengel A, Menevse S
J Clin Lab Anal. 2009
PubMed ID: 19623647
Chloroform extract of cigarette smoke induces proliferation of human esophageal squamous-cell carcinoma cells: modulation by beta-adrenoceptors.
Li P, Wu WK, Wong HP, Zhang ST, Yu L, Cho CH
Drug Chem Toxicol. 2009
PubMed ID: 19538012
Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart.
Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann AJ
Br J Pharmacol. 2009
PubMed ID: 19133992
Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications.
Snitker S, Fujishima Y, Shen H, Ott S, Pi-Sunyer X, Furuhata Y, Sato H, Takahashi M
Am J Clin Nutr. 2009
PubMed ID: 19056576
Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure.
Harris DM, Chen X, Pesant S, Cohn HI, MacDonnell SM, Boucher M, Vinge LE, Raake P, Moraca SR, Li D, Most P, Houser SR, Koch WJ, Eckhart AD
J Mol Cell Cardiol. 2009
PubMed ID: 18930063
Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy.
Bouxsein ML, Devlin MJ, Glatt V, Dhillon H, Pierroz DD, Ferrari SL
Endocrinology. 2009
PubMed ID: 18801900
Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.
Angers M, Uldry M, Kong D, Gimble JM, Jetten AM
Biochem J. 2008
PubMed ID: 18694395
Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, The Psychiatric Genetics Network GroupComplete list of members appeared as Supplementary Note.
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 19086053
Bitransgenesis with beta(2)-adrenergic receptors or adenylyl cyclase fails to improve beta(1)-adrenergic receptor cardiomyopathy.
Petrashevskaya N, Gaume BR, Mihlbachler KA, Dorn GW, Liggett SB
Clin Transl Sci. 2008
PubMed ID: 20443853
Gene expression of adrenoceptors in the hearts of cold-acclimated rats exposed to a novel stressor.
Tillinger A, Myslivecek J, Nováková M, Krizanova O, Kvetnanský R
Ann N Y Acad Sci. 2008
PubMed ID: 19120133
Adrenoceptors and adaptive mechanisms in the heart during stress.
Spadari-Bratfisch RC, dos Santos IN
Ann N Y Acad Sci. 2008
PubMed ID: 19120131
[Effect of substance P on expression of beta1-adrenergic receptor in cultured rat cardiomyocytes]
Ma YX, Guo Z
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2008
PubMed ID: 19111114
An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic rats.
Ceolotto G, Papparella I, Sticca A, Bova S, Cavalli M, Cargnelli G, Semplicini A, Gatta A, Angeli P
Hepatology. 2008
PubMed ID: 19003918
Effect of stellate ganglionectomy on basal cardiovascular function and responses to beta1-adrenoceptor blockade in the rat.
Yoshimoto M, Wehrwein EA, Novotny M, Swain GM, Kreulen DL, Osborn JW
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18931026
cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes.
Patrizio M, Vago V, Musumeci M, Fecchi K, Sposi NM, Mattei E, Catalano L, Stati T, Marano G
J Mol Cell Cardiol. 2008
PubMed ID: 18851973
Distinct interactions of human beta1- and beta2-adrenoceptors with isoproterenol, epinephrine, norepinephrine, and dopamine.
Weitl N, Seifert R
J Pharmacol Exp Ther. 2008
PubMed ID: 18772317
[Interactions between beta1 and beta2 adrenergic receptor polymorphisms as risk factors for chronic heart failure]
Moraga F, Troncoso R, Mellado R, Díaz-Araya G, Vukasovic JL, Greig D, Perez O, García L, Roldán J, Ocaranza MP, Jali J, Chiong M, Castro P
Rev Med Chil. 2008
PubMed ID: 19301767
beta-Adrenergic blockers: a 50-year historical perspective.
Frishman WH
Am J Ther. 2008
PubMed ID: 19127141
Effects of polymorphism of the beta(1) adrenoreceptor and CYP2D6 on the therapeutic effects of metoprolol.
Yuan H, Huang Z, Yang G, Lv H, Sang H, Yao Y
J Int Med Res. 2008
PubMed ID: 19094446
Genetic polymorphisms of beta1 adrenergic receptor and their influence on the cardiovascular responses to metoprolol in a South Indian population.
Mahesh Kumar KN, Ramu P, Rajan S, Shewade DG, Balachander J, Adithan C
J Cardiovasc Pharmacol. 2008
PubMed ID: 19033826
Correlation between beta-adrenoceptors and G-protein-coupled receptor kinases in pretransplantation heart failure.
Agüero J, Almenar L, D'Ocon P, Oliver E, Montó F, Moro J, Castelló A, Rueda J, Martínez-Dolz L, Sánchez-Lazaro I, Montero JA
Transplant Proc. 2008
PubMed ID: 19010176
Multiple interactions between the alpha2C- and beta1-adrenergic receptors influence heart failure survival.
Kardia SL, Kelly RJ, Keddache MA, Aronow BJ, Grabowski GA, Hahn HS, Case KL, Wagoner LE, Dorn GW, Liggett SB
BMC Med Genet. 2008
PubMed ID: 18947427
Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.
Lasky-Su J, Anney RJ, Neale BM, Franke B, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV
Am J Med Genet B Neuropsychiatr Genet. 2008
PubMed ID: 18937294
Prevalence in the United States of Selected Candidate Gene Variants: Third National Health and Nutrition Examination Survey, 1991-1994.
Chang MH, Lindegren ML, Butler MA, Chanock SJ, Dowling NF, Gallagher M, Moonesinghe R, Moore CA, Ned RM, Reichler MR, Sanders CL, Welch R, Yesupriya A, Khoury MJ, for the CDC/NCI NHANES III Genomics Working Group
Am J Epidemiol. 2008
PubMed ID: 18936436
Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome.
Crowley JJ, Lipsky RH, Lucki I, Berrettini WH
Psychiatr Genet. 2008
PubMed ID: 18797399
Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.
Kurnik D, Li C, Sofowora GG, Friedman EA, Muszkat M, Xie HG, Harris PA, Williams SM, Nair UB, Wood AJ, Stein CM
Pharmacogenet Genomics. 2008
PubMed ID: 18794726
Impact of beta1-adrenergic receptor polymorphisms on susceptibility to heart failure, arrhythmogenesis, prognosis, and response to beta-blocker therapy.
Biolo A, Clausell N, Santos KG, Salvaro R, Ashton-Prolla P, Borges A, Rohde LE
Am J Cardiol. 2008
PubMed ID: 18773997
The beta1-adrenergic receptor mediates the pharmacogenetic interaction of the ACE D allele and beta-blockers.
Ishizawar DC, Janosko KM, Teuteberg JJ, Cadaret LM, Mathier MA, McNamara DM
Clin Transl Sci. 2008
PubMed ID: 20443839
Association study between reward dependence temperament and a polymorphism in the phenylethanolamine N-methyltransferase gene in a Japanese female population.
Yamano E, Isowa T, Nakano Y, Matsuda F, Hashimoto-Tamaoki T, Ohira H, Kosugi S
Compr Psychiatry. 2008
PubMed ID: 18702937
Single nucleotide polymorphisms in genes of circulatory homeostasis in surviving pediatric intensive care patients with meningococcal infection.
Bunker-Wiersma HE, Koopmans RP, Kuipers TW, Knoester H, Bos AP
Pediatr Crit Care Med. 2008
PubMed ID: 18679149
Voluntary exercise-induced changes in beta2-adrenoceptor signalling in rat ventricular myocytes.
Stones R, Natali A, Billeter R, Harrison S, White E
Exp Physiol. 2008
PubMed ID: 18487315
Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion.
Wu Q, Zhao Z, Sun H, Hao YL, Yan CD, Gu SL
Exp Physiol. 2008
PubMed ID: 18469068
Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol.
Sehnert AJ, Daniels SE, Elashoff M, Wingrove JA, Burrow CR, Horne B, Muhlestein JB, Donahue M, Liggett SB, Anderson JL, Kraus WE
J Am Coll Cardiol. 2008
PubMed ID: 18702968
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.
Raake PW, Vinge LE, Gao E, Boucher M, Rengo G, Chen X, DeGeorge BR, Matkovich S, Houser SR, Most P, Eckhart AD, Dorn GW, Koch WJ
Circ Res. 2008
PubMed ID: 18635825
Job strain, job demands and adrenergic beta1-receptor-polymorphism: a possible interaction affecting blood pressure in men.
Ohlin B, Berglund G, Nilsson PM, Melander O
J Hypertens. 2008
PubMed ID: 18622236
beta-Adrenergic Receptor Gene Polymorphisms and beta-Blocker Treatment Outcomes in Hypertension.
Pacanowski M, Gong Y, Cooper-Dehoff R, Schork N, Shriver M, Langaee T, Pepine C, Johnson J
Clin Pharmacol Ther. 2008
PubMed ID: 18615004
Blood pressure and metabolic phenotypes in relation to the ADRB1 Arg389Gly and ADRA2B I/D polymorphisms in a White population.
Tikhonoff V, Hasenkamp S, Kuznetsova T, Thijs L, Jin Y, Richart T, Zhang H, Brand-Herrmann SM, Brand E, Casiglia E, Staessen JA
J Hum Hypertens. 2008
PubMed ID: 18596718
Beta1- and alpha2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry.
Woodiwiss AJ, Badenhorst D, Sliwa K, Brooksbank R, Essop R, Sareli P, Norton GR
Cardiovasc J Afr. 2008
PubMed ID: 18776959
Intraocular pressure response to topical beta-blockers associated with an ADRB2 single-nucleotide polymorphism.
McCarty CA, Burmester JK, Mukesh BN, Patchett RB, Wilke RA
Arch Ophthalmol. 2008
PubMed ID: 18625943
Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.
Galandrin S, Oligny-Longpré G, Bonin H, Ogawa K, Galés C, Bouvier M
Mol Pharmacol. 2008
PubMed ID: 18403719
Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.
Luttrell LM
Mol Biotechnol. 2008
PubMed ID: 18240029
Corticotropin-releasing factor in the basolateral amygdala enhances memory consolidation via an interaction with the beta-adrenoceptor-cAMP pathway: dependence on glucocorticoid receptor activation.
Roozendaal B, Schelling G, McGaugh JL
J Neurosci. 2008
PubMed ID: 18579737
Transient tachypnea of the newborn (TTN): A role for polymorphisms in the beta-adrenergic receptor (ADRB) encoding genes?
Aslan E, Tutdibi E, Martens S, Han Y, Monz D, Gortner L
Acta Paediatr. 2008
PubMed ID: 18540901
Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.
Tseng ZH, Aouizerat BE, Pawlikowska L, Vittinghoff E, Lin F, Whiteman D, Poon A, Herrington D, Howard TD, Varosy PD, Hulley SB, Malloy M, Kane J, Kwok PY, Olgin JE
Heart Rhythm. 2008
PubMed ID: 18534365
Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia.
van der Net JB, van Etten J, Yazdanpanah M, Dallinga-Thie GM, Kastelein JJ, Defesche JC, Koopmans RP, Steyerberg EW, Sijbrands EJ
Eur Heart J. 2008
PubMed ID: 18413308
Expression and functional role of beta-adrenoceptors in the human urinary bladder urothelium.
Otsuka A, Shinbo H, Matsumoto R, Kurita Y, Ozono S
Naunyn Schmiedebergs Arch Pharmacol. 2008
PubMed ID: 18311486
Beta-adrenoceptor alterations coupled with secretory response and experimental periodontitis in rat submandibular glands.
Busch L, Sterin-Borda L, Borda E
Arch Oral Biol. 2008
PubMed ID: 18275933
Role of beta1-adrenoceptor in the basolateral amygdala of rats with anxiety-like behavior.
Fu A, Li X, Zhao B
Brain Res. 2008
PubMed ID: 18423428
beta1- and beta2-adrenoceptor induced synaptic facilitation in rat basolateral amygdala.
Abraham PA, Xing G, Zhang L, Yu EZ, Post R, Gamble EH, Li H
Brain Res. 2008
PubMed ID: 18396264
beta(1) and beta(2)-Adrenergic Receptor Polymorphisms and Idiopathic Ventricular Arrhythmias.
Ulucan C, Cetintas V, Tetik A, Eroglu Z, Kayikcioglu M, Can LH, Payzin S, Aydin M, Hasdemir C
J Cardiovasc Electrophysiol. 2008
PubMed ID: 18479335
HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification.
Shaut CA, Keene DR, Sorensen LK, Li DY, Stadler HS
PLoS Genet. 2008
PubMed ID: 18483557
Polymorphisms in multiple genes are associated with resting heart rate in a stepwise allele-dependent manner.
Wilton SB, Anderson TJ, Parboosingh J, Bridge PJ, Exner DV, Forrest D, Duff HJ
Heart Rhythm. 2008
PubMed ID: 18452871
Mutations in the beta1 adrenergic receptor gene and massive obesity in Japanese.
Ohshiro Y, Hayashi M, Yabiku K, Ueda K, Wakasaki H, Ishigame M, Furuta H, Nishi M, Sasaki H, Takasu N, Nanjo K
Diabetes Res Clin Pract. 2008
PubMed ID: 18346809
Persistence of circadian variation in arterial blood pressure in beta1/beta2-adrenergic receptor-deficient mice.
Kim SM, Huang Y, Qin Y, Mizel D, Schnermann J, Briggs JP
Am J Physiol Regul Integr Comp Physiol. 2008
PubMed ID: 18305025
Cardioprotective and survival benefits of long-term combined therapy with beta2 adrenoreceptor (AR) agonist and beta1 AR blocker in dilated cardiomyopathy postmyocardial infarction.
Ahmet I, Krawczyk M, Zhu W, Woo AY, Morrell C, Poosala S, Xiao RP, Lakatta EG, Talan MI
J Pharmacol Exp Ther. 2008
PubMed ID: 18287209
Beta1-adrenoceptors in rat anterior pituitary may be constitutively active. Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels.
Janssens K, Boussemaere M, Wagner S, Kopka K, Denef C
Endocrinology. 2008
PubMed ID: 18202135
Beta1-adrenoceptor expression in rat anterior pituitary gonadotrophs and in mouse alphaT3-1 and LbetaT2 gonadotrophic cell lines.
Janssens K, Krylyshkina O, Hersmus N, Vankelecom H, Denef C
Endocrinology. 2008
PubMed ID: 18202120
Association of beta1-adrenergic receptor genetic polymorphism with mental stress-induced myocardial ischemia in patients with coronary artery disease.
Hassan M, York KM, Li H, Li Q, Gong Y, Langaee TY, Fillingim RB, Johnson JA, Sheps DS
Arch Intern Med. 2008
PubMed ID: 18413560
[Genetic study of the vasovagal syncope associated to the Arg389Gly polymorphism of the beta1 adrenergic receptor]
Hernández-Pacheco G, Serrano H, Márquez MF, Hermosillo AG, Pérez-Vielma N, Sotomayor A, Ferreira-Vidal AD, Salas-Silva E, Cárdenas M
Arch Cardiol Mex. 2008
PubMed ID: 18754404
Benefits of long-term beta-blockade in experimental chronic aortic regurgitation.
Plante E, Lachance D, Champetier S, Drolet MC, Roussel E, Arsenault M, Couet J
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18296565
Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality.
Swoap SJ, Li C, Wess J, Parsons AD, Williams TD, Overton JM
Am J Physiol Heart Circ Physiol. 2008
PubMed ID: 18245567
Endocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytes.
Morisco C, Marrone C, Galeotti J, Shao D, Vatner DE, Vatner SF, Sadoshima J
Cardiovasc Res. 2008
PubMed ID: 18194989
Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart.
Gourine A, Bondar SI, Spyer KM, Gourine AV
Circ Res. 2008
PubMed ID: 18323523
Labetalol facilitates GABAergic transmission to rat periaqueductal gray neurons via antagonizing beta1-adrenergic receptors--a possible mechanism underlying labetalol-induced analgesia.
Xiao C, Zhou C, Atlas G, Delphin E, Ye JH
Brain Res. 2008
PubMed ID: 18262504
Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome.
Schwartz PJ, Vanoli E, Crotti L, Spazzolini C, Ferrandi C, Goosen A, Hedley P, Heradien M, Bacchini S, Turco A, La Rovere MT, Bartoli A, George AL, Brink PA
J Am Coll Cardiol. 2008
PubMed ID: 18308161
beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke.
Lemaitre RN, Heckbert SR, Sotoodehnia N, Bis JC, Smith NL, Marciante KD, Hindorff LA, Lange LA, Lumley TS, Rice KM, Wiggins KL, Psaty BM
Am J Hypertens. 2008
PubMed ID: 18219297
Norepinephrine suppresses gonadotropin-releasing hormone neuron excitability in the adult mouse.
Han SK, Herbison AE
Endocrinology. 2008
PubMed ID: 18079196
Association of beta (1)-adrenergic receptor gene polymorphisms with left ventricular hypertrophy in human essential hypertension.
Fu C, Wang H, Wang S, Shi Y, Zhou X, Sun K, Chen J, Song X, Xue H, Hui R
Clin Biochem. 2008
PubMed ID: 18298953
beta-Adrenergic receptor gene polymorphisms and hemodynamic response to dobutamine during dobutamine stress echocardiography.
Aquilante CL, Yarandi HN, Cavallari LH, Andrisin TE, Terra SG, Lewis JF, Hamilton KK, Johnson JA
Pharmacogenomics J. 2008
PubMed ID: 18253135
Adrenergic beta1 receptor polymorphism (Ser49Gly) is associated with obesity in type II diabetic patients.
Nonen S, Yamamoto I, Liu J, Maeda M, Motomura T, Igarashi T, Fujio Y, Azuma J
Biol Pharm Bull. 2008
PubMed ID: 18239290
beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart.
Brito-Martins M, Harding SE, Ali NN
Br J Pharmacol. 2008
PubMed ID: 18193079
Knockout of beta(1)- and beta(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis.
Kiriazis H, Wang K, Xu Q, Gao XM, Ming Z, Su Y, Moore XL, Lambert G, Gibbs ME, Dart AM, Du XJ
Br J Pharmacol. 2008
PubMed ID: 18193078
Adoptive passive transfer of rabbit beta1-adrenoceptor peptide immune cardiomyopathy into the Rag2-/- mouse: participation of the ER stress.
Liu J, Mao W, Iwai C, Fukuoka S, Vulapalli R, Huang H, Wang T, Sharma VK, Sheu SS, Fu M, Liang CS
J Mol Cell Cardiol. 2008
PubMed ID: 18155231
Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac beta(1)-adrenoceptors.
Galindo-Tovar A, Kaumann AJ
Br J Pharmacol. 2008
PubMed ID: 18084319
Partial left ventricular unloading reverses contractile dysfunction and helps recover gene expressions in failing rat hearts.
Wang J, Marui A, Ikeda T, Komeda M
Interact Cardiovasc Thorac Surg. 2008
PubMed ID: 18006556
Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.
Wang Y, De Arcangelis V, Gao X, Ramani B, Jung YS, Xiang Y
J Biol Chem. 2008
PubMed ID: 18056263
Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4.
Richter W, Day P, Agrawal R, Bruss MD, Granier S, Wang YL, Rasmussen SG, Horner K, Wang P, Lei T, Patterson AJ, Kobilka B, Conti M
EMBO J. 2008
PubMed ID: 18188154
Adrenergic regulation of a key cardiac potassium channel can contribute to atrial fibrillation: evidence from an I Ks transgenic mouse.
Sampson KJ, Terrenoire C, Cervantes DO, Kaba RA, Peters NS, Kass RS
J Physiol. 2008
PubMed ID: 18006587
Beta1- and beta2-adrenoceptors in basolateral nucleus of amygdala and their roles in consolidation of fear memory in rats.
Qu LL, Guo NN, Li BM
Hippocampus. 2008
PubMed ID: 18680159
[Genetic aspects of individual sensitivity to betaxolol in patients with arterial hypertension.]
Minushkina LO, Zateishchikova AA, Zateishchikov DA, Mankhaeva BB, Savel'eva EG, Kochkina MS, Brovkin AV, Nikitin AG, Nosikov VV, Sidorenko BA
Kardiologiia. 2008
PubMed ID: 18429752
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation.
Pacanowski MA, Zineh I, Li H, Johnson BD, Cooper-DeHoff RM, Bittner V, McNamara DM, Sharaf BL, Merz CN, Pepine CJ, Johnson JA
J Transl Med. 2008
PubMed ID: 18331634
High concentrations of landiolol, a beta(1)-adrenoceptor antagonist, stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway.
Shibata O, Nishioka K, Yamaguchi M, Makita T, Sumikawa K
J Anesth. 2008
PubMed ID: 18306009
Genetic variation within the beta1-adrenergic receptor gene results in haplotype-specific expression phenotypes.
Small KM, Mialet-Perez J, Liggett SB
J Cardiovasc Pharmacol. 2008
PubMed ID: 18209576
Role of beta adrenergic receptor polymorphisms in heart failure: systematic review and meta-analysis.
Muthumala A, Drenos F, Elliott PM, Humphries SE
Eur J Heart Fail. 2008
PubMed ID: 18158268
Role of beta1-, beta2-, and beta3-adrenoceptors in contractile hypersensitivity in a model of small bowel transplantation.
Rickenbacher A, Seiler R, Honegger U, Shaw SG, Balsiger BM
Surgery. 2008
PubMed ID: 18154937
Association of ADRB1 and UCP3 gene polymorphisms with insulin sensitivity but not obesity.
Mottagui-Tabar S, Hoffstedt J, Brookes AJ, Jiao H, Arner P, Dahlman I
Horm Res. 2008
PubMed ID: 18059082
EMMPRIN mediates beta-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes.
Siwik DA, Kuster GM, Brahmbhatt JV, Zaidi Z, Malik J, Ooi H, Ghorayeb G
J Mol Cell Cardiol. 2008
PubMed ID: 17869266
Greater glycogen utilization during 1- than 2-adrenergic receptor stimulation in the isolated perfused rat heart.
McConville P, Lakatta EG, Spencer RG
Am J Physiol Endocrinol Metab. 2007
PubMed ID: 17911346
Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure.
Perrino C, Schroder JN, Lima B, Villamizar N, Nienaber JJ, Milano CA, Naga Prasad SV
Circulation. 2007
PubMed ID: 17998459
Down-regulation of beta1-adrenoceptors gene expression by short interfering RNA impairs the memory retrieval in the basolateral amygdala of rats.
Fu AL, Yan XB, Sui L
Neurosci Lett. 2007
PubMed ID: 17961922
Arg389Gly-beta1-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol.
Chen L, Meyers D, Javorsky G, Burstow D, Lolekha P, Lucas M, Semmler AB, Savarimuthu SM, Fong KM, Yang IA, Atherton J, Galbraith AJ, Parsonage WA, Molenaar P
Pharmacogenet Genomics. 2007
PubMed ID: 18075464
The central melanocortin system directly controls peripheral lipid metabolism.
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH
J Clin Invest. 2007
PubMed ID: 17885689
Association of beta-adrenoceptor polymorphisms with cardiac autonomic modulation in Japanese males.
Matsunaga T, Yasuda K, Adachi T, Gu N, Yamamura T, Moritani T, Tsujimoto G, Tsuda K
Am Heart J. 2007
PubMed ID: 17893006
Immunohistochemical localization of adrenergic receptors in the rat organ of corti and spiral ganglion.
Khan KM, Drescher MJ, Hatfield JS, Ramakrishnan NA, Drescher DG
J Neurosci Res. 2007
PubMed ID: 17671986
Genetic variation associated with ischemic heart failure: a HuGE review and meta-analysis.
Kitsios G, Zintzaras E
Am J Epidemiol. 2007
PubMed ID: 17644825
Cardiac reserve in the transplanted heart: effect of a graft polymorphism in the beta1-adrenoceptor.
Scharin Täng M, Lindberg E, Grüner Sveälv B, Magnusson Y, Andersson B
J Heart Lung Transplant. 2007
PubMed ID: 17845930
Effects of milrinone on contractility and cyclic adenosine monophosphate production induced by beta1- and beta2-adrenergic receptor activation in human myocardium.
Carceles MD, Fuentes T, Aroca V, Lopez J, Hernández J
Clin Ther. 2007
PubMed ID: 17919552
[389A/G polymorphism of the human beta1-adrenergic receptor in patients with acute myocardial infarction]
Song YL, Wu XZ, Guo G, Zhang HX, Yang YQ
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007
PubMed ID: 17680533
Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathy.
Forleo C, Sorrentino S, Guida P, Romito R, De Tommasi E, Iacoviello M, Pitzalis M
J Cardiovasc Med (Hagerstown). 2007
PubMed ID: 17667029
Association of CYP2D6 and ADRB1 genes with hypotensive and antichronotropic action of betaxolol in patients with arterial hypertension.
Zateyshchikov DA, Minushkina LO, Brovkin AN, Savel'eva EG, Zateyshchikova AA, Manchaeva BB, Nikitin AG, Sidorenko BA, Nosikov VV
Fundam Clin Pharmacol. 2007
PubMed ID: 17635183
The Arg389Gly beta1-adrenergic receptor gene polymorphism and susceptibility to faint during head-up tilt test.
Márquez MF, Hernández-Pacheco G, Hermosillo AG, Gómez JR, Cárdenas M, Vargas-Alarcón G
Europace. 2007
PubMed ID: 17463065
Interethnic differences in drug response: the contribution of genetic variability in beta adrenergic receptor and cytochrome P4502C9.
Muszkat M
Clin Pharmacol Ther. 2007
PubMed ID: 17329986
Adrenergic receptor genotype but not perioperative bisoprolol therapy may determine cardiovascular outcome in at-risk patients undergoing surgery with spinal block: the Swiss Beta Blocker in Spinal Anesthesia (BBSA) study: a double-blinded, placebo-contro
Zaugg M, Bestmann L, Wacker J, Lucchinetti E, Boltres A, Schulz C, Hersberger M, Kälin G, Furrer L, Hofer C, Blumenthal S, Müller A, Zollinger A, Spahn DR, Borgeat A
Anesthesiology. 2007
PubMed ID: 17585213
In patients chronically treated with metoprolol, the demand of inotropic catecholamine support after coronary artery bypass grafting is determined by the Arg389Gly-beta 1-adrenoceptor polymorphism.
Leineweber K, Bogedain P, Wolf C, Wagner S, Weber M, Jakob HG, Heusch G, Philipp T, Brodde OE
Naunyn Schmiedebergs Arch Pharmacol. 2007
PubMed ID: 17541557
Regulation of renin secretion and expression in mice deficient in beta1- and beta2-adrenergic receptors.
Kim SM, Chen L, Faulhaber-Walter R, Oppermann M, Huang Y, Mizel D, Briggs JP, Schnermann J
Hypertension. 2007
PubMed ID: 17515456
An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.
Miura S, Kawanaka K, Kai Y, Tamura M, Goto M, Shiuchi T, Minokoshi Y, Ezaki O
Endocrinology. 2007
PubMed ID: 17446185
Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations.
Lima JJ, Feng H, Duckworth L, Wang J, Sylvester JE, Kissoon N, Garg H
Metabolism. 2007
PubMed ID: 17512307
Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.
Paavonen KJ, Swan H, Piippo K, Laitinen P, Fodstad H, Sarna S, Toivonen L, Kontula K, Viitasalo M
Int J Cardiol. 2007
PubMed ID: 17023080
Sema3a maintains normal heart rhythm through sympathetic innervation patterning.
Ieda M, Kanazawa H, Kimura K, Hattori F, Ieda Y, Taniguchi M, Lee JK, Matsumura K, Tomita Y, Miyoshi S, Shimoda K, Makino S, Sano M, Kodama I, Ogawa S, Fukuda K
Nat Med. 2007
PubMed ID: 17417650
Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.
Meyers KJ, Mosley TH, Fox E, Boerwinkle E, Arnett DK, Devereux RB, Kardia SL
Hypertension. 2007
PubMed ID: 17339538
Cellular and subcellular distributions of beta1- and beta2-adrenoceptors in the CA1 and CA3 regions of the rat hippocampus.
Guo NN, Li BM
Neuroscience. 2007
PubMed ID: 17337326
Beta1-adrenergic receptors on immune cells impair innate defenses against Listeria.
Emeny RT, Gao D, Lawrence DA
J Immunol. 2007
PubMed ID: 17404268
[Association of beta-adrenoceptor gene polymorphism with resting heart rate]
Niu Y, Xie Z, Yin Y
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007
PubMed ID: 17591269
Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure.
Lobmeyer MT, Gong Y, Terra SG, Beitelshees AL, Langaee TY, Pauly DF, Schofield RS, Hamilton KK, Herbert Patterson J, Adams KF, Hill JA, Aranda JM, Johnson JA
Pharmacogenet Genomics. 2007
PubMed ID: 17496726
A prospective evaluation of left ventricular remodeling after inaugural anterior myocardial infarction as a function of gene polymorphisms in the renin-angiotensin-aldosterone, adrenergic, and metalloproteinase systems.
Bauters C, Lamblin N, Ennezat PV, Mycinski C, Tricot O, Nugue O, Segrestin B, Hannebicque G, Agraou B, Polge AS, de Groote P, Helbecque N, Amouyel P, REVE Investigators
Am Heart J. 2007
PubMed ID: 17383306
Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.
Gjesing AP, Andersen G, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O
Diabet Med. 2007
PubMed ID: 17335470
Association of gene polymorphisms with blood pressure and the prevalence of hypertension in community-dwelling Japanese individuals.
Yamada Y, Ando F, Shimokata H
Int J Mol Med. 2007
PubMed ID: 17334644
Cardiac dilatation and pump dysfunction without intrinsic myocardial systolic failure following chronic beta-adrenoreceptor activation.
Osadchii OE, Norton GR, McKechnie R, Deftereos D, Woodiwiss AJ
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17158652
Impaired hippocampal LTP in inbred mouse strains can be rescued by beta-adrenergic receptor activation.
Schimanski LA, Ali DW, Baker GB, Nguyen PV
Eur J Neurosci. 2007
PubMed ID: 17425584
Relation of beta(2)-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure.
Shin J, Lobmeyer MT, Gong Y, Zineh I, Langaee TY, Yarandi H, Schofield RS, Aranda JM, Hill JA, Pauly DF, Johnson JA
Am J Cardiol. 2007
PubMed ID: 17223428
Golgin-160 promotes cell surface expression of the beta-1 adrenergic receptor.
Hicks SW, Horn TA, McCaffery JM, Zuckerman DM, Machamer CE
Traffic. 2006
PubMed ID: 17118120
Characterization of cardiopulmonary function and cardiac muscarinic and adrenergic receptor density adaptation in C57BL/6 mice with chronic Trypanosoma cruzi infection.
Rocha NN, Garcia S, Giménez LE, Hernández CC, Senra JF, Lima RS, Cyrino F, Bouskela E, Soares MB, Ribeiro dos Santos R, Campos de Carvalho AC
Parasitology. 2006
PubMed ID: 16978452
AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptor.
Gardner LA, Tavalin SJ, Goehring AS, Scott JD, Bahouth SW
J Biol Chem. 2006
PubMed ID: 16940053
Genetic influences of beta-adrenoceptor polymorphisms on arterial functional changes and cardiac remodeling in hypertensive patients.
Yuan M, Ohishi M, Ito N, Sugimoto K, Takagi T, Terai M, Katsuya T, Rakugi H, Wu Z, Ogihara T
Hypertens Res. 2006
PubMed ID: 17345787
Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems.
Tutor AS, Delpón E, Caballero R, Gómez R, Núñez L, Vaquero M, Tamargo J, Mayor F, Penela P
Mol Biol Cell. 2006
PubMed ID: 16914520
Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test.
Crowley JJ, Brodkin ES, Blendy JA, Berrettini WH, Lucki I
Neuropsychopharmacology. 2006
PubMed ID: 16554742
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation.
Hulme JT, Westenbroek RE, Scheuer T, Catterall WA
Proc Natl Acad Sci U S A. 2006
PubMed ID: 17053072
CRM 1-mediated degradation and agonist-induced down-regulation of beta-adrenergic receptor mRNAs.
Bai Y, Lu H, Machida CA
Biochim Biophys Acta. 2006
PubMed ID: 16997396
[Beta1-adrenergic receptor (Arg389Gly) polymorphism and response to bisoprolol in patients with chronic heart failure]
Yu WP, Lou M, Deng B, Song HM, Wang HB
Zhonghua Xin Xue Guan Bing Za Zhi. 2006
PubMed ID: 17217681
Adrenergic receptor polymorphisms associated with resting heart rate: the HyperGEN Study.
Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC
Ann Hum Genet. 2006
PubMed ID: 16907703
Selective upregulation of beta1-adrenergic receptors and dephosphorylation of troponin I in end-stage heart failure patients supported by ventricular assist devices.
Milting H, Scholz C, Arusoglu L, Freitag M, Cebulla R, Jaquet K, Körfer R, V Lewinski D, Kassner A, Brodde OE, Kögler H, El Banayosy A, Pieske B
J Mol Cell Cardiol. 2006
PubMed ID: 16765375
Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists.
Zeitoun O, Santos NM, Gardner LA, White SW, Bahouth SW
Mol Pharmacol. 2006
PubMed ID: 16760361
The control of UCP1 is dissociated from that of PGC-1alpha or of mitochondriogenesis as revealed by a study using beta-less mouse brown adipocytes in culture.
Lehr L, Canola K, Asensio C, Jimenez M, Kuehne F, Giacobino JP, Muzzin P
FEBS Lett. 2006
PubMed ID: 16876797
Influence of lipoprotein lipase gene Ser447Stop and beta1-adrenergic receptor gene Arg389Gly polymorphisms and their interaction on obesity from childhood to adulthood: the Bogalusa Heart Study.
Li S, Chen W, Srinivasan SR, Boerwinkle E, Berenson GS
Int J Obes (Lond). 2006
PubMed ID: 16534528
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure.
Liggett SB, Mialet-Perez J, Thaneemit-Chen S, Weber SA, Greene SM, Hodne D, Nelson B, Morrison J, Domanski MJ, Wagoner LE, Abraham WT, Anderson JL, Carlquist JF, Krause-Steinrauf HJ, Lazzeroni LC, Port JD, Lavori PW, Bristow MR
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16844790
Autoantibody against cardiac beta1-adrenoceptor induces apoptosis in cultured neonatal rat cardiomyocytes.
Gao Y, Liu HR, Zhao RR, Zhi JM
Acta Biochim Biophys Sin (Shanghai). 2006
PubMed ID: 16820859
beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension.
Liu J, Liu ZQ, Yu BN, Xu FH, Mo W, Zhou G, Liu YZ, Li Q, Zhou HH
Clin Pharmacol Ther. 2006
PubMed ID: 16815314
Ghrelin action in the brain controls adipocyte metabolism.
Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schürmann A, Szanto I, Tschöp MH, Rohner-Jeanrenaud F
J Clin Invest. 2006
PubMed ID: 16767221
Adrenoceptor polymorphisms and the risk of cardiac injury and dysfunction after subarachnoid hemorrhage.
Zaroff JG, Pawlikowska L, Miss JC, Yarlagadda S, Ha C, Achrol A, Kwok PY, McCulloch CE, Lawton MT, Ko N, Smith W, Young WL
Stroke. 2006
PubMed ID: 16728691
Functional beta-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes.
Boivin B, Lavoie C, Vaniotis G, Baragli A, Villeneuve LR, Ethier N, Trieu P, Allen BG, Hébert TE
Cardiovasc Res. 2006
PubMed ID: 16631628
Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
Behr B, Hoffmann C, Ottolina G, Klotz KN
J Biol Chem. 2006
PubMed ID: 16648137
Beta1-adrenergic receptor gene polymorphisms in Mexican patients with idiopathic dilated cardiomyopathy.
Fragoso JM, Rodríguez-Pérez JM, González J, Cruz D, Pérez-Méndez O, de Jesus García J, de la Peña A, Arce M, Reyes PA, Vargas-Alarcón G
Exp Mol Pathol. 2006
PubMed ID: 16487965
Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins.
Delos Santos NM, Gardner LA, White SW, Bahouth SW
J Biol Chem. 2006
PubMed ID: 16500896
Influence of phenotype and pharmacokinetics on beta-blocker drug target pharmacogenetics.
Beitelshees AL, Zineh I, Yarandi HN, Pauly DF, Johnson JA
Pharmacogenomics J. 2006
PubMed ID: 16402084
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Myocardial beta1-adrenergic receptor polymorphisms affect functional recovery after ischemic injury.
Akhter SA, D'Souza KM, Petrashevskaya NN, Mialet-Perez J, Liggett SB
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16537791
The CAREGENE study: polymorphisms of the beta1-adrenoceptor gene and aerobic power in coronary artery disease.
Defoor J, Martens K, Zielinska D, Matthijs G, Van Nerum H, Schepers D, Fagard R, Vanhees L
Eur Heart J. 2006
PubMed ID: 16421173
Differential cardiotoxic/cardioprotective effects of beta-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy.
Fajardo G, Zhao M, Powers J, Bernstein D
J Mol Cell Cardiol. 2006
PubMed ID: 16458323
Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.
He J, Bellini M, Inuzuka H, Xu J, Xiong Y, Yang X, Castleberry AM, Hall RA
J Biol Chem. 2006
PubMed ID: 16316992
Effects of polymorphisms in beta1-adrenoceptor and alpha-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study.
Nieminen T, Lehtimäki T, Laiho J, Rontu R, Niemelä K, Kööbi T, Lehtinen R, Viik J, Turjanmaa V, Kähönen M
J Appl Physiol. 2006
PubMed ID: 16210433
Beta2-adrenergic receptor polymorphisms are associated with asthma and COPD in adults.
Matheson MC, Ellis JA, Raven J, Johns DP, Walters EH, Abramson MJ
J Hum Genet. 2006
PubMed ID: 16946993
Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.
Inagaki Y, Mashima Y, Fuse N, Funayama T, Ohtake Y, Yasuda N, Murakami A, Hotta Y, Fukuchi T, Tsubota K
Mol Vis. 2006
PubMed ID: 16785856
What role do adrenoreceptor polymorphisms play in modifying cardiovascular responses in obstructive sleep apnoea?
McArdle N
Clin Sci (Lond). 2006
PubMed ID: 16287427
Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart rate and blood pressure in patients with obstructive sleep apnoea.
Börgel J, Schulz T, Bartels NK, Epplen JT, Büchner N, Rump LC, Huesing A, Sanner BM, Mügge A
Clin Sci (Lond). 2006
PubMed ID: 16122377
Effect of targeted deletions of beta1- and beta2-adrenergic-receptor subtypes on heart rate variability.
Ecker PM, Lin CC, Powers J, Kobilka BK, Dubin AM, Bernstein D
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16113068
Beta1-adrenergic receptor polymorphisms and clinical efficacy of betaxolol hydrochloride in normal volunteers.
Schwartz SG, Puckett BJ, Allen RC, Castillo IG, Leffler CT
Ophthalmology. 2005
PubMed ID: 16325708
Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study.
Nieminen T, Uusitalo H, Mäenpää J, Turjanmaa V, Rane A, Lundgren S, Ropo A, Rontu R, Lehtimäki T, Kähönen M
Eur J Clin Pharmacol. 2005
PubMed ID: 16315032
Differential cardioprotective/cardiotoxic effects mediated by beta-adrenergic receptor subtypes.
Bernstein D, Fajardo G, Zhao M, Urashima T, Powers J, Berry G, Kobilka BK
Am J Physiol Heart Circ Physiol. 2005
PubMed ID: 16040722
The impact of beta-adrenoreceptor gene polymorphisms on survival in patients with congestive heart failure.
de Groote P, Lamblin N, Helbecque N, Mouquet F, Mc Fadden E, Hermant X, Amouyel P, Dallongeville J, Bauters C
Eur J Heart Fail. 2005
PubMed ID: 16227135
No positive association between adrenergic receptor variants of alpha2cDel322-325, beta1Ser49, beta1Arg389 and the risk for heart failure in the Japanese population.
Nonen S, Okamoto H, Akino M, Matsui Y, Fujio Y, Yoshiyama M, Takemoto Y, Yoshikawa J, Azuma J, Kitabatake A
Br J Clin Pharmacol. 2005
PubMed ID: 16187973
Beta2-adrenergic receptor genotype and survival among patients receiving beta-blocker therapy after an acute coronary syndrome.
Lanfear DE, Jones PG, Marsh S, Cresci S, McLeod HL, Spertus JA
JAMA. 2005
PubMed ID: 16189366
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes.
Head BP, Patel HH, Roth DM, Lai NC, Niesman IR, Farquhar MG, Insel PA
J Biol Chem. 2005
PubMed ID: 15961389
Ser49Gly of beta1-adrenergic receptor is associated with effective beta-blocker dose in dilated cardiomyopathy.
Magnusson Y, Levin MC, Eggertsen R, Nyström E, Mobini R, Schaufelberger M, Andersson B
Clin Pharmacol Ther. 2005
PubMed ID: 16153393
Tumor necrosis factor-alpha mediates the proliferation of rat C6 glioma cells via beta-adrenergic receptors.
Lung HL, Shan SW, Tsang D, Leung KN
J Neuroimmunol. 2005
PubMed ID: 16005083
Norepinephrine induces lipolysis in beta1/beta2/beta3-adrenoceptor knockout mice.
Tavernier G, Jimenez M, Giacobino JP, Hulo N, Lafontan M, Muzzin P, Langin D
Mol Pharmacol. 2005
PubMed ID: 15939797
Temporal dynamics of inotropic, chronotropic, and metabolic responses during beta1- and beta2-AR stimulation in the isolated, perfused rat heart.
McConville P, Spencer RG, Lakatta EG
Am J Physiol Endocrinol Metab. 2005
PubMed ID: 15840637
Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.
Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP
Circ Res. 2005
PubMed ID: 16002745
Beta1 adrenergic receptor polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo populations of Mexico.
Fragoso JM, Rodríguez-Pérez JM, Pérez-Vielma N, Martínez-Rodríguez N, Vargas-Alarcón G
Hum Biol. 2005
PubMed ID: 16485781
Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study.
Terra SG, McGorray SP, Wu R, McNamara DM, Cavallari LH, Walker JR, Wallace MR, Johnson BD, Bairey Merz CN, Sopko G, Pepine CJ, Johnson JA
Int J Obes (Lond). 2005
PubMed ID: 15917856
Expression of beta adrenergic receptors in mouse oocytes and preimplantation embryos.
Cikos S, Veselá J, Il'ková G, Rehák P, Czikková S, Koppel J
Mol Reprod Dev. 2005
PubMed ID: 15791602
beta1-Adrenoceptor gene polymorphism predicts long-term changes in body weight.
Linné Y, Dahlman I, Hoffstedt J
Int J Obes (Lond). 2005
PubMed ID: 15685248
[The relationship between expressions of beta1-, beta2-, beta3-adrenoceptor mRNA of myocardium and cardiac function in patients with heart failure]
Li ZK, Zhu SJ, Yu LJ, Tian Y, Zhou YZ, Wang J
Zhonghua Xin Xue Guan Bing Za Zhi. 2005
PubMed ID: 15932670
Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy.
Terra SG, Hamilton KK, Pauly DF, Lee CR, Patterson JH, Adams KF, Schofield RS, Belgado BS, Hill JA, Aranda JM, Yarandi HN, Johnson JA
Pharmacogenet Genomics. 2005
PubMed ID: 15864115
Functional adrenergic receptor polymorphisms and idiopathic orthostatic intolerance.
Winker R, Barth A, Valic E, Maier R, Osterode W, Pilger A, Rüdiger HW
Int Arch Occup Environ Health. 2005
PubMed ID: 15719258
Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure.
de Groote P, Helbecque N, Lamblin N, Hermant X, Mc Fadden E, Foucher-Hossein C, Amouyel P, Dallongeville J, Bauters C
Pharmacogenet Genomics. 2005
PubMed ID: 15861037
Interactive effects between polymorphisms in the beta-adrenergic receptors and longitudinal changes in obesity.
Ellsworth DL, Coady SA, Chen W, Srinivasan SR, Boerwinkle E, Berenson GS
Obes Res. 2005
PubMed ID: 15833937
beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure.
Terra SG, Pauly DF, Lee CR, Patterson JH, Adams KF, Schofield RS, Belgado BS, Hamilton KK, Aranda JM, Hill JA, Yarandi HN, Walker JR, Phillips MS, Gelfand CA, Johnson JA
Clin Pharmacol Ther. 2005
PubMed ID: 15735607
Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.
Hosoda C, Koshimizu TA, Tanoue A, Nasa Y, Oikawa R, Tomabechi T, Fukuda S, Shinoura H, Oshikawa S, Takeo S, Kitamura T, Cotecchia S, Tsujimoto G
Mol Pharmacol. 2005
PubMed ID: 15598970
The 15-amino acid motif of the C terminus of the beta2-adrenergic receptor is sufficient to confer insulin-stimulated counterregulation to the beta1-adrenergic receptor.
Gavi S, Yin D, Shumay E, Wang HY, Malbon CC
Endocrinology. 2005
PubMed ID: 15388645
A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated so
Heydorn A, Søndergaard BP, Ersbøll B, Holst B, Nielsen FC, Haft CR, Whistler J, Schwartz TW
J Biol Chem. 2004
PubMed ID: 15452121
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
Leblais V, Jo SH, Chakir K, Maltsev V, Zheng M, Crow MT, Wang W, Lakatta EG, Xiao RP
Circ Res. 2004
PubMed ID: 15539636
PKA-mediated phosphorylation of the beta1-adrenergic receptor promotes Gs/Gi switching.
Martin NP, Whalen EJ, Zamah MA, Pierce KL, Lefkowitz RJ
Cell Signal. 2004
PubMed ID: 15381255
Interaction with cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) inhibits beta1-adrenergic receptor surface expression.
He J, Bellini M, Xu J, Castleberry AM, Hall RA
J Biol Chem. 2004
PubMed ID: 15358775
Interaction between cardiac sympathetic drive and heart rate in heart failure: modulation by adrenergic receptor genotype.
Kaye DM, Smirk B, Finch S, Williams C, Esler MD
J Am Coll Cardiol. 2004
PubMed ID: 15542284
Resistance of the human beta1-adrenergic receptor to agonist-induced ubiquitination: a mechanism for impaired receptor degradation.
Liang W, Fishman PH
J Biol Chem. 2004
PubMed ID: 15331590
The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.
Matayoshi T, Kamide K, Takiuchi S, Yoshii M, Miwa Y, Takami Y, Tanaka C, Banno M, Horio T, Nakamura S, Nakahama H, Yoshihara F, Inenaga T, Miyata T, Kawano Y
Hypertens Res. 2004
PubMed ID: 15824464
The Arg389Gly beta1-adrenoceptor gene polymorphism determines contractile response to catecholamines.
La Rosée K, Huntgeburth M, Rosenkranz S, Böhm M, Schnabel P
Pharmacogenetics. 2004
PubMed ID: 15564877
Variants in the human beta 1-, beta 2-, and beta 3-adrenergic receptor genes are not associated with morbid obesity in children and adolescents.
Tafel J, Branscheid I, Skwarna B, Schlimme M, Morcos M, Algenstaedt P, Hinney A, Hebebrand J, Nawroth P, Hamann A
Diabetes Obes Metab. 2004
PubMed ID: 15479221
Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway.
Wang W, Zhu W, Wang S, Yang D, Crow MT, Xiao RP, Cheng H
Circ Res. 2004
PubMed ID: 15375008
Control of 4E-BP1 expression in mouse brown adipose tissue by the beta3-adrenoceptor.
Lehr L, Kuehne F, Arboit P, Giacobino JP, Poulin F, Muzzin P, Jimenez M
FEBS Lett. 2004
PubMed ID: 15474034
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy.
Forleo C, Resta N, Sorrentino S, Guida P, Manghisi A, De Luca V, Romito R, Iacoviello M, De Tommasi E, Troisi F, Rizzon B, Guanti G, Rizzon P, Pitzalis MV
Am J Med. 2004
PubMed ID: 15464701
Role of beta1- and beta2-adrenoceptor polymorphisms in heart failure: a case-control study.
Covolo L, Gelatti U, Metra M, Nodari S, Piccichè A, Pezzali N, Zani C, Alberti A, Donato F, Nardi G, Dei Cas L
Eur Heart J. 2004
PubMed ID: 15342173
A polymorphism of the beta1-adrenergic receptor is associated with low extraversion.
Stein MB, Schork NJ, Gelernter J
Biol Psychiatry. 2004
PubMed ID: 15312808
Polymorphism in genes involved in adrenergic signaling associated with Alzheimer's.
Bullido MJ, Ramos MC, Ruiz-Gómez A, Tutor AS, Sastre I, Frank A, Coria F, Gil P, Mayor F, Valdivieso F
Neurobiol Aging. 2004
PubMed ID: 15212839
Frequency of compound genotypes associated with beta-blocker efficacy in congestive heart failure.
Lanfear DE, Marsh S, Cresci S, Spertus JA, McLeod HL
Pharmacogenomics. 2004
PubMed ID: 15212591
Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension.
Karlsson J, Lind L, Hallberg P, Michaëlsson K, Kurland L, Kahan T, Malmqvist K, Ohman KP, Nyström F, Melhus H
Clin Cardiol. 2004
PubMed ID: 15237695
The DNA sequence and comparative analysis of human chromosome 10.
Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L, Steward CA, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE, Andrews TD, Gilbert JG, Swarbreck D, Ashurst JL, Taylor A, Battles J, Bird CP, Ainscough R, Almeida JP, Ashwell RI, Ambrose KD, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H, Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Cahill P, Camire D, Carter NP, Chapman JC, Clark SY, Clarke G, Clee CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S, Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E, Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C, Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK, Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE, McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou T, Sehra HK, Shownkeen R, Skuce CD, Smith M, Standring L, Sycamore N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J, Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK, Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T, Doucette-Stamm L, Beck S, Smith DR, Rogers J
Nature. 2004
PubMed ID: 15164054
Role of the cyclic AMP-dependent protein kinase in homologous resensitization of the beta1-adrenergic receptor.
Gardner LA, Delos Santos NM, Matta SG, Whitt MA, Bahouth SW
J Biol Chem. 2004
PubMed ID: 14990580
The genetic association database.
Becker KG, Barnes KC, Bright TJ, Wang SA
Nat Genet. 2004
PubMed ID: 15118671
Identification of a novel family of G protein-coupled receptor associated sorting proteins.
Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL
J Neurochem. 2004
PubMed ID: 15086532
Upregulation of alveolar epithelial active Na+ transport is dependent on beta2-adrenergic receptor signaling.
Mutlu GM, Dumasius V, Burhop J, McShane PJ, Meng FJ, Welch L, Dumasius A, Mohebahmadi N, Thakuria G, Hardiman K, Matalon S, Hollenberg S, Factor P
Circ Res. 2004
PubMed ID: 15016730
A distinct role for norepinephrine in memory retrieval.
Murchison CF, Zhang XY, Zhang WP, Ouyang M, Lee A, Thomas SA
Cell. 2004
PubMed ID: 15066288
[The genotype analysis of beta adrenergic receptor gene family in high risk population of hypertension in northeast China]
Liang Y, Zhao YY, Liu H, Shi JP
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004
PubMed ID: 15079793
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD
Nat Med. 2004
PubMed ID: 14966518
Differences in endosomal targeting of human (beta)1- and (beta)2-adrenergic receptors following clathrin-mediated endocytosis.
Liang W, Curran PK, Hoang Q, Moreland RT, Fishman PH
J Cell Sci. 2004
PubMed ID: 14734649
Association of beta-adrenoceptor single nucleotide polymorphisms with resting heart rate.
Xie ZX, Niu YH, Ma HX, Yin YH, Liu ZZ, Li ZY
Conf Proc IEEE Eng Med Biol Soc. 2004
PubMed ID: 17270896
Association between hypertension and the alpha-adducin, beta1-adrenoreceptor, and G-protein beta3 subunit genes in the Japanese population; the Suita study.
Shioji K, Kokubo Y, Mannami T, Inamoto N, Morisaki H, Mino Y, Tagoi N, Yasui N, Iwaii N
Hypertens Res. 2004
PubMed ID: 15055253
Effects of endothelial nitric oxide synthase, alpha-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide.
Turner ST, Chapman AB, Schwartz GL, Boerwinkle E
Am J Hypertens. 2003
PubMed ID: 14553962
Gly389Arg polymorphism of beta1-adrenergic receptor is associated with the cardiovascular response to metoprolol.
Liu J, Liu ZQ, Tan ZR, Chen XP, Wang LS, Zhou G, Zhou HH
Clin Pharmacol Ther. 2003
PubMed ID: 14534524
Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.
Mialet Perez J, Rathz DA, Petrashevskaya NN, Hahn HS, Wagoner LE, Schwartz A, Dorn GW, Liggett SB
Nat Med. 2003
PubMed ID: 14502278
Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox.
McGraw DW, Almoosa KF, Paul RJ, Kobilka BK, Liggett SB
J Clin Invest. 2003
PubMed ID: 12925702
An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study.
White HL, de Boer RA, Maqbool A, Greenwood D, van Veldhuisen DJ, Cuthbert R, Ball SG, Hall AS, Balmforth AJ, MERIT-HF Study Group
Eur J Heart Fail. 2003
PubMed ID: 12921807
Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor.
Maack C, Böhm M, Vlaskin L, Dabew E, Lorenz K, Schäfers HJ, Lohse MJ, Engelhardt S
Circulation. 2003
PubMed ID: 12847069
GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation.
Hu LA, Chen W, Martin NP, Whalen EJ, Premont RT, Lefkowitz RJ
J Biol Chem. 2003
PubMed ID: 12724327
Arg389Gly polymorphism of the human beta1-adrenergic receptor in patients with nonfatal acute myocardial infarction.
Iwai C, Akita H, Kanazawa K, Shiga N, Terashima M, Matsuda Y, Takai E, Miyamoto Y, Shimizu M, Kajiya T, Hayashi T, Yokoyama M
Am Heart J. 2003
PubMed ID: 12851615
Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol.
Johnson JA, Zineh I, Puckett BJ, McGorray SP, Yarandi HN, Pauly DF
Clin Pharmacol Ther. 2003
PubMed ID: 12844134
Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response.
Zill P, Baghai TC, Engel R, Zwanzger P, Schüle C, Minov C, Behrens S, Bottlender R, Jäger M, Rupprecht R, Möller HJ, Ackenheil M, Bondy B
Am J Med Genet B Neuropsychiatr Genet. 2003
PubMed ID: 12815745
Epinephrine promotes pulmonary angiitis: evidence for a beta1-adrenoreceptor-mediated mechanism.
Jain FA, Zhao LH, Selig MK, Kradin RL
Am J Physiol Lung Cell Mol Physiol. 2003
PubMed ID: 12730078
Activation of beta1-adrenoceptors excites striatal cholinergic interneurons through a cAMP-dependent, protein kinase-independent pathway.
Pisani A, Bonsi P, Centonze D, Martorana A, Fusco F, Sancesario G, De Persis C, Bernardi G, Calabresi P
J Neurosci. 2003
PubMed ID: 12832552
Regulation of cardiac beta 1-adrenergic receptor transcription during the developmental transition.
Wadhawan R, Tseng YT, Stabila J, McGonnigal B, Sarkar S, Padbury J
Am J Physiol Heart Circ Physiol. 2003
PubMed ID: 12742828
Effects of common polymorphisms in the alpha1A-, alpha2B-, beta1- and beta2-adrenoreceptors on haemodynamic responses to adrenaline.
Snapir A, Koskenvuo J, Toikka J, Orho-Melander M, Hinkka S, Saraste M, Hartiala J, Scheinin M
Clin Sci (Lond). 2003
PubMed ID: 12519093
A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade.
Sofowora GG, Dishy V, Muszkat M, Xie HG, Kim RB, Harris PA, Prasad HC, Byrne DW, Nair UB, Wood AJ, Stein CM
Clin Pharmacol Ther. 2003
PubMed ID: 12709726
Acute cold/restraint stress inhibits host resistance to Listeria monocytogenes via beta1-adrenergic receptors.
Cao L, Hudson CA, Lawrence DA
Brain Behav Immun. 2003
PubMed ID: 12676574
Heterodimerization of alpha 2A- and beta 1-adrenergic receptors.
Xu J, He J, Castleberry AM, Balasubramanian S, Lau AG, Hall RA
J Biol Chem. 2003
PubMed ID: 12529373
The genetic determination of left ventricular mass in healthy adults.
Swan L, Birnie DH, Padmanabhan S, Inglis G, Connell JM, Hillis WS
Eur Heart J. 2003
PubMed ID: 12643891
Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.
Zhu WZ, Wang SQ, Chakir K, Yang D, Zhang T, Brown JH, Devic E, Kobilka BK, Cheng H, Xiao RP
J Clin Invest. 2003
PubMed ID: 12618516
A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.
Liljedahl U, Karlsson J, Melhus H, Kurland L, Lindersson M, Kahan T, Nyström F, Lind L, Syvänen AC
Pharmacogenetics. 2003
PubMed ID: 12544508
Opposite action of beta1- and beta2-adrenergic receptors on Ca(V)1 L-channel current in rat adrenal chromaffin cells.
Cesetti T, Hernández-Guijo JM, Baldelli P, Carabelli V, Carbone E
J Neurosci. 2003
PubMed ID: 12514203
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer.
Mercier JF, Salahpour A, Angers S, Breit A, Bouvier M
J Biol Chem. 2002
PubMed ID: 12244098
Polymorphisms of the beta1-adrenergic receptor predict exercise capacity in heart failure.
Wagoner LE, Craft LL, Zengel P, McGuire N, Rathz DA, Dorn GW, Liggett SB
Am Heart J. 2002
PubMed ID: 12422153
Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.
Pak Y, Pham N, Rotin D
Mol Cell Biol. 2002
PubMed ID: 12391161
Beta(1)/beta(2)/beta(3)-adrenoceptor knockout mice are obese and cold-sensitive but have normal lipolytic responses to fasting.
Jimenez M, Léger B, Canola K, Lehr L, Arboit P, Seydoux J, Russell AP, Giacobino JP, Muzzin P, Preitner F
FEBS Lett. 2002
PubMed ID: 12387862
Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure.
Small KM, Wagoner LE, Levin AM, Kardia SL, Liggett SB
N Engl J Med. 2002
PubMed ID: 12374873
Glycosylation of beta(1)-adrenergic receptors regulates receptor surface expression and dimerization.
He J, Xu J, Castleberry AM, Lau AG, Hall RA
Biochem Biophys Res Commun. 2002
PubMed ID: 12270132
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.
Lavoie C, Mercier JF, Salahpour A, Umapathy D, Breit A, Villeneuve LR, Zhu WZ, Xiao RP, Lakatta EG, Bouvier M, Hébert TE
J Biol Chem. 2002
PubMed ID: 12140284
The PDZ binding motif of the beta 1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes.
Xiang Y, Devic E, Kobilka B
J Biol Chem. 2002
PubMed ID: 12097326
Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure.
Stanton T, Inglis GC, Padmanabhan S, Dominiczak AF, Jardine AG, Connell JM
J Nephrol. 2002
PubMed ID: 12455717
Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Lemon WJ, Bernert H, Sun H, Wang Y, You M
J Med Genet. 2002
PubMed ID: 12205107
Interaction of neuronal nitric oxide synthase with alpha1-adrenergic receptor subtypes in transfected HEK-293 cells.
Pupo AS, Minneman KP
BMC Pharmacol. 2002
PubMed ID: 12184796
Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.
Feldman DS, Zamah AM, Pierce KL, Miller WE, Kelly F, Rapacciuolo A, Rockman HA, Koch WJ, Luttrell LM
J Biol Chem. 2002
PubMed ID: 12036966
betaAR signaling required for diet-induced thermogenesis and obesity resistance.
Bachman ES, Dhillon H, Zhang CY, Cinti S, Bianco AC, Kobilka BK, Lowell BB
Science. 2002
PubMed ID: 12161655
Suppressive effect of the Gly389 allele of the beta1-adrenergic receptor gene on the occurrence of ventricular tachycardia in dilated cardiomyopathy.
Iwai C, Akita H, Shiga N, Takai E, Miyamoto Y, Shimizu M, Kawai H, Takarada A, Kajiya T, Yokoyama M
Circ J. 2002
PubMed ID: 12197595
Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants.
Wenzel-Seifert K, Liu HY, Seifert R
Biochem Pharmacol. 2002
PubMed ID: 12106601
An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals at risk of coronary events. A WOSCOPS substudy.
White HL, Maqbool A, McMahon AD, Yates L, Ball SG, Hall AS, Balmforth AJ
Eur Heart J. 2002
PubMed ID: 12090746
Complexity of agonist- and cyclic AMP-mediated downregulation of the human beta 1-adrenergic receptor: role of internalization, degradation, and mRNA destabilization.
Dunigan CD, Hoang Q, Curran PK, Fishman PH
Biochemistry. 2002
PubMed ID: 12069593
Inhibition of betaARK1 restores impaired biochemical beta-adrenergic receptor responsiveness but does not rescue CREB(A133) induced cardiomyopathy.
Eckhart AD, Fentzke RC, Lepore J, Lang R, Lin H, Lefkowitz RJ, Koch WJ, Leiden JM
J Mol Cell Cardiol. 2002
PubMed ID: 12054854
Sudden infant death: no evidence for linkage to common polymorphisms in the uncoupling protein-1 and the beta3-adrenergic receptor genes.
Fatemi A, Item C, Stöckler-Ipsiroglu S, Ipsiroglu O, Sperl W, Patsch W, Strobl W
Eur J Pediatr. 2002
PubMed ID: 12029453
Variability within alpha- and beta-adrenoreceptor genes as a predictor of cardiovascular function at rest and in response to mental challenge.
McCaffery JM, Pogue-Geile MF, Ferrell RE, Petro N, Manuck SB
J Hypertens. 2002
PubMed ID: 12023679
Association between obesity and a polymorphism in the beta(1)-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women.
Dionne IJ, Garant MJ, Nolan AA, Pollin TI, Lewis DG, Shuldiner AR, Poehlman ET
Int J Obes Relat Metab Disord. 2002
PubMed ID: 12032746
A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate.
Ranade K, Jorgenson E, Sheu WH, Pei D, Hsiung CA, Chiang FT, Chen YD, Pratt R, Olshen RA, Curb D, Cox DR, Botstein D, Risch N
Am J Hum Genet. 2002
PubMed ID: 11854867
Polymorphisms in beta-adrenergic receptor genes in the acquired long QT syndrome.
Kanki H, Yang P, Xie HG, Kim RB, George AL, Roden DM
J Cardiovasc Electrophysiol. 2002
PubMed ID: 11942593
G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95.
Hu LA, Chen W, Premont RT, Cong M, Lefkowitz RJ
J Biol Chem. 2002
PubMed ID: 11700307
A knockout approach indicates a minor vasoconstrictor role for vascular alpha1B-adrenoceptors in mouse.
Daly CJ, Deighan C, McGee A, Mennie D, Ali Z, McBride M, McGrath JC
Physiol Genomics. 2002
PubMed ID: 12006674
Adrenergic regulation of cardiac myocyte apoptosis.
Singh K, Xiao L, Remondino A, Sawyer DB, Colucci WS
J Cell Physiol. 2001
PubMed ID: 11748583
A putative beta2-adrenoceptor from the rainbow trout (Oncorhynuchus mykiss). Molecular characterization and pharmacology.
Nickerson JG, Dugan SG, Drouin G, Moon TW
Eur J Biochem. 2001
PubMed ID: 11737201
beta 1-adrenergic receptor association with the synaptic scaffolding protein membrane-associated guanylate kinase inverted-2 (MAGI-2). Differential regulation of receptor internalization by MAGI-2 and PSD-95.
Xu J, Paquet M, Lau AG, Wood JD, Ross CA, Hall RA
J Biol Chem. 2001
PubMed ID: 11526121
The Arg 389 Gly beta1-adrenergic receptor gene polymorphism and human fat cell lipolysis.
Rydén M, Hoffstedt J, Eriksson P, Bringman S, Arner P
Int J Obes Relat Metab Disord. 2001
PubMed ID: 11753577
Differential distribution of beta-adrenergic receptor subtypes in blood vessels of knockout mice lacking beta(1)- or beta(2)-adrenergic receptors.
Chruscinski A, Brede ME, Meinel L, Lohse MJ, Kobilka BK, Hein L
Mol Pharmacol. 2001
PubMed ID: 11641423
Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice.
Devic E, Xiang Y, Gould D, Kobilka B
Mol Pharmacol. 2001
PubMed ID: 11502890
Ontogeny of humoral heart rate regulation in the embryonic mouse.
Porter GA, Rivkees SA
Am J Physiol Regul Integr Comp Physiol. 2001
PubMed ID: 11448841
Polymorphism in the beta(1)-adrenergic receptor gene and hypertension.
Bengtsson K, Melander O, Orho-Melander M, Lindblad U, Ranstam J, Råstam L, Groop L
Circulation. 2001
PubMed ID: 11447084
Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo.
Xie HG, Dishy V, Sofowora G, Kim RB, Landau R, Smiley RM, Zhou HH, Wood AJ, Harris P, Stein CM
Pharmacogenetics. 2001
PubMed ID: 11337934
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors.
Hu LA, Tang Y, Miller WE, Cong M, Lau AG, Lefkowitz RJ, Hall RA
J Biol Chem. 2000
PubMed ID: 10995758
A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.
Comings DE, Gade-Andavolu R, Gonzalez N, Wu S, Muhleman D, Blake H, Mann MB, Dietz G, Saucier G, MacMurray JP
Clin Genet. 2000
PubMed ID: 11140838
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure.
Börjesson M, Magnusson Y, Hjalmarson A, Andersson B
Eur Heart J. 2000
PubMed ID: 11052857
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors.
Shiina T, Kawasaki A, Nagao T, Kurose H
J Biol Chem. 2000
PubMed ID: 10862778
Beta1-adrenoceptor gene variations: a role in idiopathic dilated cardiomyopathy?
Podlowski S, Wenzel K, Luther HP, Müller J, Bramlage P, Baumann G, Felix SB, Speer A, Hetzer R, Köpke K, Hoehe MR, Wallukat G
J Mol Med. 2000
PubMed ID: 10794544
Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein.
Communal C, Singh K, Sawyer DB, Colucci WS
Circulation. 1999
PubMed ID: 10577992
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.
Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P, Lefkowitz RJ
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10535961
Racial differences in the frequencies of cardiac beta(1)-adrenergic receptor polymorphisms: analysis of c145A>G and c1165G>C.
Moore JD, Mason DA, Green SA, Hsu J, Liggett SB
Hum Mutat. 1999
PubMed ID: 10477438
Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse.
Asai K, Yang GP, Geng YJ, Takagi G, Bishop S, Ishikawa Y, Shannon RP, Wagner TE, Vatner DE, Homcy CJ, Vatner SF
J Clin Invest. 1999
PubMed ID: 10487769
Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors.
Rohrer DK, Chruscinski A, Schauble EH, Bernstein D, Kobilka BK
J Biol Chem. 1999
PubMed ID: 10358009
Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.
Engelhardt S, Hein L, Wiesmann F, Lohse MJ
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10359838
Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.
Cho MC, Rao M, Koch WJ, Thomas SA, Palmiter RD, Rockman HA
Circulation. 1999
PubMed ID: 10338466
A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor.
Mason DA, Moore JD, Green SA, Liggett SB
J Biol Chem. 1999
PubMed ID: 10212248
Exploring the role of the beta-adrenergic receptor kinase in cardiac disease using gene-targeted mice.
Koch WJ, Rockman HA
Trends Cardiovasc Med. 1999
PubMed ID: 10578521
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
SH3 binding domains in the dopamine D4 receptor.
Oldenhof J, Vickery R, Anafi M, Oak J, Ray A, Schoots O, Pawson T, von Zastrow M, Van Tol HH
Biochemistry. 1998
PubMed ID: 9843378
Physiological consequences of beta-adrenergic receptor disruption.
Rohrer DK
J Mol Med. 1998
PubMed ID: 9826121
Alterations in dynamic heart rate control in the beta 1-adrenergic receptor knockout mouse.
Rohrer DK, Schauble EH, Desai KH, Kobilka BK, Bernstein D
Am J Physiol. 1998
PubMed ID: 9575921
Differential regulation by tumor necrosis factor-alpha of beta1-, beta2-, and beta3-adrenoreceptor gene expression in 3T3-F442A adipocytes.
Hadri KE, Courtalon A, Gauthereau X, Chambaut-Guérin AM, Pairault J, Fève B
J Biol Chem. 1997
PubMed ID: 9305915
Cardiac function in genetically engineered mice with altered adrenergic receptor signaling.
Rockman HA, Koch WJ, Lefkowitz RJ
Am J Physiol. 1997
PubMed ID: 9139936
Comparative mapping of novel simple sequence repeat markers in a hypertension-related region on rat chromosome 1.
Nabika T, Ito T, Kitada K, Serikawa T, Mashimo T, Soubrier F, Julier C, Ohno Y, Saruta T, Tanase H, Masuda J, Yamori Y, Nara Y
Mamm Genome. 1997
PubMed ID: 9069124
Role of beta-adrenergic and cholinergic systems in acclimatization to hypoxia in the rat.
Clancy RL, Moue Y, Erwig LP, Smith PG, Gonzalez NC
Respir Physiol. 1997
PubMed ID: 9089896
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.
Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8917529
Structural and functional analysis of the B cell epitopes recognized by anti-receptor autoantibodies in patients with Chagas' disease.
Elies R, Ferrari I, Wallukat G, Lebesgue D, Chiale P, Elizari M, Rosenbaum M, Hoebeke J, Levin MJ
J Immunol. 1996
PubMed ID: 8892658
Genetic maps of polymorphic DNA loci on rat chromosome 1.
Ding YP, Remmers EF, Du Y, Longman RE, Goldmuntz EA, Zha H, Kotake S, Cannon GW, Griffiths MM, Wilder RL
Genomics. 1996
PubMed ID: 8812459
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
Rohrer DK, Desai KH, Jasper JR, Stevens ME, Regula DP, Barsh GS, Bernstein D, Kobilka BK
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8693001
Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Kozak CA, Adamson MC, Buckler CE, Segovia L, Paralkar V, Wistow G
Genomics. 1995
PubMed ID: 7558020
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ
Science. 1995
PubMed ID: 7761854
Genetic mapping of adrenergic receptor genes in humans.
Hoehe MR, Otterud B, Hsieh WT, Martinez MM, Stauffer D, Holik J, Berrettini WH, Byerley WF, Gershon ES, Lalouel JM
J Mol Med. 1995
PubMed ID: 7583452
Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines.
Rohlfs EM, Daniel KW, Premont RT, Kozak LP, Collins S
J Biol Chem. 1995
PubMed ID: 7738011
Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus.
Keller SA, Jones JM, Boyle A, Barrow LL, Killen PD, Green DG, Kapousta NV, Hitchcock PF, Swank RT, Meisler MH
Genomics. 1994
PubMed ID: 7835879
Molecular map of chromosome 19 including three genes affecting bleeding time: ep, ru, and bm.
O'Brien EP, Novak EK, Keller SA, Poirier C, Guénet JL, Swank RT
Mamm Genome. 1994
PubMed ID: 8043950
Effects of beta 1- and beta 2-adrenoceptor agonists applied into the hypothalamic paraventricular nuclei of spontaneously hypertensive rats on urine production.
Tsushima H, Fujimoto S, Matsuda T
Jpn J Pharmacol. 1994
PubMed ID: 7912752
Primary structure of the mouse beta 1-adrenergic receptor gene.
Jasper JR, Link RE, Chruscinski AJ, Kobilka BK, Bernstein D
Biochim Biophys Acta. 1993
PubMed ID: 8395893
Characterization of a mouse beta 1-adrenergic receptor genomic clone.
Cohen JA, Baggott LA, Romano C, Arai M, Southerling TE, Young LH, Kozak CA, Molinoff PB, Greene MI
DNA Cell Biol. 1993
PubMed ID: 8392347
Corrected centromere orientation for mouse chromosome 19 MIT markers.
Eicher EM, Shown EP, Bhat D, Seldin MF
Mamm Genome. 1993
PubMed ID: 8499657
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
Watson ML, Rao JK, Gilkeson GS, Ruiz P, Eicher EM, Pisetsky DS, Matsuzawa A, Rochelle JM, Seldin MF
J Exp Med. 1992
PubMed ID: 1460423
A linkage map of mouse chromosome 19: definition of comparative mapping relationships with human chromosomes 10 and 11 including the MEN1 locus.
Rochelle JM, Watson ML, Oakey RJ, Seldin MF
Genomics. 1992
PubMed ID: 1358795
The specific binding of broxaterol, a new beta 2-selective agonist, to beta-adrenoceptors.
Sala R, Moriggi E, Della Bella D, Carenzi A
Eur J Pharmacol. 1991
PubMed ID: 1686765
Isolation and molecular characterization of the B cells producing the paraprotein in a case of benign monoclonal gammapathy in C57BL mice.
Bos NA, Meeuwsen CG, De Glopper-Van der Veer E, Van den Akker TW, Radl J, Zwaagstra KA, Benner R
Eur J Immunol. 1991
PubMed ID: 1868874
Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution.
Oakey RJ, Caron MG, Lefkowitz RJ, Seldin MF
Genomics. 1991
PubMed ID: 1676978
Primary structure of the rat beta-1 adrenergic receptor gene.
Shimomura H, Terada A
Nucleic Acids Res. 1990
PubMed ID: 2167473
Molecular cloning and expression of the rat beta 1-adrenergic receptor gene.
Machida CA, Bunzow JR, Searles RP, Van Tol H, Tester B, Neve KA, Teal P, Nipper V, Civelli O
J Biol Chem. 1990
PubMed ID: 1695899
Chromosomal organization of adrenergic receptor genes.
Yang-Feng TL, Xue FY, Zhong WW, Cotecchia S, Frielle T, Caron MG, Lefkowitz RJ, Francke U
Proc Natl Acad Sci U S A. 1990
PubMed ID: 2154750
Long-term treatment of angina pectoris with bisoprolol or atenolol in patients with chronic obstructive bronchitis: a randomized, double-blind crossover study.
Dorow P, Thalhofer S, Bethge H, Disselhoff G, Wagner G
J Cardiovasc Pharmacol. 1990
PubMed ID: 11527135
The effect of Escherichia coli endotoxin on the adrenergic control of lipolysis in the human adipocyte.
Forse RA, Leibel R, Gagner M
J Surg Res. 1989
PubMed ID: 2536864
Human beta 1- and beta 2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes.
Frielle T, Kobilka B, Lefkowitz RJ, Caron MG
Trends Neurosci. 1988
PubMed ID: 2465637
Cloning of the cDNA for the human beta 1-adrenergic receptor.
Frielle T, Collins S, Daniel KW, Caron MG, Lefkowitz RJ, Kobilka BK
Proc Natl Acad Sci U S A. 1987
PubMed ID: 2825170
Beta-adrenoreceptors in rat brown adipose tissue: proportions of beta 1- and beta 2-subtypes.
Rothwell NJ, Stock MJ, Sudera DK
Am J Physiol. 1985
PubMed ID: 2858976
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
Ruffolo RR, Goldberg MR, Morgan EL
J Pharmacol Exp Ther. 1984
PubMed ID: 6381693
The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling.
Stiles GL, Strasser RH, Lavin TN, Jones LR, Caron MG, Lefkowitz RJ
J Biol Chem. 1983
PubMed ID: 6305985
Analysis of the beta 1 and beta 2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria.
Cohen ML, Wiley KS, Bemis KG
Naunyn Schmiedebergs Arch Pharmacol. 1982
PubMed ID: 6289140

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	Human	Mouse	Rat
Entrez Gene	153	11554	24925
EnsEMBL Gene(s)	ENSG00000043591	ENSMUSG00000035283	ENSRNOG00000017002
Unigene	Hs.99913	Mm.46797	Rn.87064
Homologene	ADRB1	Adrb1	Adrb1
OMIM	109630	N/A	N/A
GeneCards	ADRB1	N/A	N/A
Beta Cell Genomics	DT.92040573	DT.40154163	N/A
Reactome	P08588	N/A	N/A
Plasma Peptide Atlas	N/A	N/A	N/A
WikiGenes	153	11554	24925

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