Home CTSL1
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(Human) GRCh37 - chr9:90340434..90346384 (5.95 kb) View in Genome Browser
HaemAtlas Expression Table for CTSL1:|
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
| Human | Mouse | Rat | ||||||||||
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| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
| no data | no data | no data | no data | no data | no data | no data | no data | |||||
Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for CTSL1:The CTSL1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| CTSL1 | BTN3A3 | IntAct | empirical | 21988832 |
| CTSL1 | CTSC | HPRD | empirical | 11327826 |
| CTSL1 | CST3 | HPRD | empirical | 10428479 |
| CTSL1 | CSTA | HPRD | empirical | 12921779 9585570 |
| CTSL1 | CSTB | HPRD | empirical | 11514663 |
| CTSL1 | CTSL1 | HPRD | empirical | 9585570 |
| CTSL1 | CUX1 | HPRD | empirical | 15099520 |
| CTSL1 | ALB | IntAct | empirical | 15174051 |
| CTSL1 | GCG | HPRD | empirical | 7340337 |
| CTSL1 | GEM | IntAct, BioGRID | empirical | 18624398 |
| CTSL1 | APOA1 | IntAct | empirical | 15174051 |
| CTSL1 | IGFBP3 | HPRD | empirical | 11801256 |
| CTSL1 | IGHA1 | IntAct | empirical | 15174051 |
| CTSL1 | IL8 | HPRD | empirical | 12818188 |
| CTSL1 | KNG1 | HPRD | empirical | 11517935 |
| CTSL1 | ARSA | HPRD | empirical | 11777924 |
| CTSL1 | SERPINB13 | HPRD | empirical | 12504904 12809493 |
| CTSL1 | PLAU | HPRD | empirical | 1551416 |
| CTSL1 | PSMD1 | Sanger Interaction Map | predicted | 15345047 |
| CTSL1 | RELB | IntAct | empirical | 21988832 |
| CTSL1 | RXRA | HPRD, BioGRID | empirical | 9918848 9837884 |
| CTSL1 | SERPINB3 | HPRD, BioGRID | empirical | 9548757 |
| CTSL1 | SLPI | HPRD | empirical | 11435427 |
| CTSL1 | TF | IntAct | empirical | 15174051 |
| CTSL1 | TG | HPRD | empirical | 1939080 |
| CTSL1 | UBC | BioGRID | empirical | 21906983 |
| CTSL1 | BAG6 | BioGRID | empirical | 21900206 |
| CTSL1 | CST7 | HPRD | empirical | 9632704 9733783 |
| CTSL1 | EED | BioGRID | empirical | 21900206 |
| CTSL1 | CD7 | HPRD | empirical | 8666891 |
| CTSL1 | CD74 | HPRD | empirical | 10022822 |
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Publications: 140
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Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis.
Klaude M, Mori M, Tjäder I, Gustafsson T, Wernerman J, Rooyackers O
Clin Sci (Lond). 2012
PubMed ID: 21880013
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Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.
Brecher M, Schornberg KL, Delos SE, Fusco ML, Saphire EO, White JM
J Virol. 2012
PubMed ID: 22031933
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Cathepsin L is highly expressed in gastrointestinal stromal tumors.
Miyamoto K, Iwadate M, Yanagisawa Y, Ito E, Imai J, Yamamoto M, Sawada N, Saito M, Suzuki S, Nakamura I, Ohki S, Saze Z, Kogure M, Gotoh M, Omicronbara K, Ohira H, Tasaki K, Abe M, Goshima N, Watanabe S, Waguri S, Takenoshita S
Int J Oncol. 2011
PubMed ID: 21769426
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Cysteine cathepsins S and L modulate anti-angiogenic activities of human endostatin.
Veillard F, Saidi A, Burden RE, Scott CJ, Gillet L, Lecaille F, Lalmanach G
J Biol Chem. 2011
PubMed ID: 21896479
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Clinical value of combined detection of serum matrix metalloproteinase-9, heparanase, and cathepsin for determining ovarian cancer invasion and metastasis.
Zhang W, Yang HC, Wang Q, Yang ZJ, Chen H, Wang SM, Pan ZM, Tang BJ, Li QQ, Li L
Anticancer Res. 2011
PubMed ID: 21965756
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Epigenetic regulation of cathepsin L expression in chronic myeloid leukaemia.
Samaiya M, Bakhshi S, Shukla AA, Kumar L, Chauhan SS
J Cell Mol Med. 2011
PubMed ID: 21496199
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A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE
Sci Signal. 2011
PubMed ID: 21900206
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Peroxisome proliferator-activated receptor gamma induces apoptosis and inhibits autophagy of human monocyte-derived macrophages via induction of cathepsin L: potential role in atherosclerosis.
Mahmood DF, Jguirim-Souissi I, Khadija el-H, Blondeau N, Diderot V, Amrani S, Slimane MN, Syrovets T, Simmet T, Rouis M
J Biol Chem. 2011
PubMed ID: 21700710
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A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.
Gonzalez-Suarez I, Redwood AB, Grotsky DA, Neumann MA, Cheng EH, Stewart CL, Dusso A, Gonzalo S
EMBO J. 2011
PubMed ID: 21750527
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Processing of human protryptase in mast cells involves cathepsins L, B, and C.
Le QT, Gomez G, Zhao W, Hu J, Xia HZ, Fukuoka Y, Katunuma N, Schwartz LB
J Immunol. 2011
PubMed ID: 21742978
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Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins.
Kulig P, Kantyka T, Zabel BA, Banas M, Chyra A, Stefanska A, Tu H, Allen SJ, Handel TM, Kozik A, Potempa J, Butcher EC, Cichy J
J Immunol. 2011
PubMed ID: 21715684
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The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
Warnatz HJ, Schmidt D, Manke T, Piccini I, Sultan M, Borodina T, Balzereit D, Wruck W, Soldatov A, Vingron M, Lehrach H, Yaspo ML
J Biol Chem. 2011
PubMed ID: 21555518
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Procathepsin L secretion, which triggers tumour progression, is regulated by Rab4a in human melanoma cells.
Barbarin A, Frade R
Biochem J. 2011
PubMed ID: 21501115
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Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7.
Kenig S, Frangež R, Pucer A, Lah T
Apoptosis. 2011
PubMed ID: 21484410
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Promiscuous processing of human alphabeta-protryptases by cathepsins L, B, and C.
Le QT, Min HK, Xia HZ, Fukuoka Y, Katunuma N, Schwartz LB
J Immunol. 2011
PubMed ID: 21562164
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The heparanase system and tumor metastasis: is heparanase the seed and soil?
Arvatz G, Shafat I, Levy-Adam F, Ilan N, Vlodavsky I
Cancer Metastasis Rev. 2011
PubMed ID: 21308479
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Post-transcriptional regulation of human cathepsin L expression.
Mittal S, Mir RA, Chauhan SS
Biol Chem. 2011
PubMed ID: 21395501
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Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer's disease.
Schechter I, Ziv E
Biol Chem. 2011
PubMed ID: 21585286
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Parkinson's disease involves autophagy and abnormal distribution of cathepsin L.
Li L, Wang X, Fei X, Xia L, Qin Z, Liang Z
Neurosci Lett. 2011
PubMed ID: 21134415
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Multiplex zymography captures stage-specific activity profiles of cathepsins K, L, and S in human breast, lung, and cervical cancer.
Chen B, Platt MO
J Transl Med. 2011
PubMed ID: 21756348
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Cathepsins are involved in virus-induced cell death in ICP4 and Us3 deletion mutant herpes simplex virus type 1-infected monocytic cells.
Peri P, Nuutila K, Vuorinen T, Saukko P, Hukkanen V
J Gen Virol. 2011
PubMed ID: 20881085
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Serum cathepsin levels in coronary artery ectasia.
Zografos TA, Haliassos A, Korovesis S, Giazitzoglou E, Serelis J, Katritsis DG
Int J Cardiol. 2010
PubMed ID: 20837372
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Cathepsins B and L in peripheral blood mononuclear cells of pediatric acute myeloid leukemia: potential poor prognostic markers.
Jain M, Bakhshi S, Shukla AA, Chauhan SS
Ann Hematol. 2010
PubMed ID: 20567828
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Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.
Sevenich L, Hagemann S, Stoeckle C, Tolosa E, Peters C, Reinheckel T
Biochimie. 2010
PubMed ID: 20347002
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Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways.
Urbanelli L, Trivelli F, Ercolani L, Sementino E, Magini A, Tancini B, Franceschini R, Emiliani C
Mol Cell Biochem. 2010
PubMed ID: 20524145
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Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
Konjar S, Sutton VR, Hoves S, Repnik U, Yagita H, Reinheckel T, Peters C, Turk V, Turk B, Trapani JA, Kopitar-Jerala N
Immunology. 2010
PubMed ID: 20497254
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[Relationship between cathepsin L and invasion and metastasis of ovarian carcinoma cells].
Wang SM, Li L, Zhang W, Li DR, Tang BJ
Zhonghua Fu Chan Ke Za Zhi. 2010
PubMed ID: 21029616
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Plasma cathepsin L and its related pro/antiangiogenic factors play useful roles in predicting rich coronary collaterals in patients with coronary heart disease.
Zhang J, Wang P, Huang YB, Li J, Zhu J, Luo X, Shi HM, Li Y
J Int Med Res. 2010
PubMed ID: 20926012
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Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells.
Pucer A, Castino R, Mirković B, Falnoga I, Slejkovec Z, Isidoro C, Lah TT
Biol Chem. 2010
PubMed ID: 20302512
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Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors.
Kolwijck E, Massuger LF, Thomas CM, Span PN, Krasovec M, Kos J, Sweep FC
J Cancer Res Clin Oncol. 2010
PubMed ID: 19915865
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Proteinuria: an enzymatic disease of the podocyte?
Mundel P, Reiser J
Kidney Int. 2010
PubMed ID: 19924101
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Stefin B interacts with histones and cathepsin L in the nucleus.
Ceru S, Konjar S, Maher K, Repnik U, Krizaj I, Bencina M, Renko M, Nepveu A, Zerovnik E, Turk B, Kopitar-Jerala N
J Biol Chem. 2010
PubMed ID: 20075068
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Cathepsin L, target in cancer treatment?
Lankelma JM, Voorend DM, Barwari T, Koetsveld J, Van der Spek AH, De Porto AP, Van Rooijen G, Van Noorden CJ
Life Sci. 2010
PubMed ID: 19958782
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Heparin enhances serpin inhibition of the cysteine protease cathepsin L.
Higgins WJ, Fox DM, Kowalski PS, Nielsen JE, Worrall DM
J Biol Chem. 2010
PubMed ID: 19959474
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Truncated human cathepsin L, encoded by a novel splice variant, exhibits altered subcellular localization and cytotoxicity.
Sansanwal P, Shukla AA, Das TK, Chauhan SS
Protein Pept Lett. 2010
PubMed ID: 19663777
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Cathepsin L is associated with proliferation and clinical outcome of urothelial carcinoma of the bladder.
Yan JA, Xiao H, Ji HX, Shen WH, Zhou ZS, Song B, Chen ZW, Li WB
J Int Med Res. 2010
PubMed ID: 21226994
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Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer.
Sullivan S, Tosetto M, Kevans D, Coss A, Wang L, O'Donoghue D, Hyland J, Sheahan K, Mulcahy H, O'Sullivan J
Int J Cancer. 2009
PubMed ID: 19291794
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Expression of cathepsin L in nasopharyngeal carcinoma and its clinical significance.
Xu X, Yuan G, Liu W, Zhang Y, Chen W
Exp Oncol. 2009
PubMed ID: 19550400
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Colocalization of cystatin M/E and its target proteases suggests a role in terminal differentiation of human hair follicle and nail.
Cheng T, van Vlijmen-Willems IM, Hitomi K, Pasch MC, van Erp PE, Schalkwijk J, Zeeuwen PL
J Invest Dermatol. 2009
PubMed ID: 19005484
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Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling.
Tang Q, Cai J, Shen D, Bian Z, Yan L, Wang YX, Lan J, Zhuang GQ, Ma WZ, Wang W
J Mol Med. 2009
PubMed ID: 19096818
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[Association of cathepsin L with coronary heart disease and its risk factors].
Wang J, Liu Y, Li X, Peng D, Tan Z, Liu H, Qin Y, Xue Y
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009
PubMed ID: 19270352
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Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
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Protease-mediated entry via the endosome of human coronavirus 229E.
Kawase M, Shirato K, Matsuyama S, Taguchi F
J Virol. 2009
PubMed ID: 18971274
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Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis.
Li W, Kornmark L, Jonasson L, Forssell C, Yuan XM
Atherosclerosis. 2009
PubMed ID: 18495127
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Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis.
Cailhier JF, Sirois I, Laplante P, Lepage S, Raymond MA, Brassard N, Prat A, Iozzo RV, Pshezhetsky AV, Hébert MJ
J Biol Chem. 2008
PubMed ID: 18658137
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Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.
Wang J, Yuan Y, Zhou Y, Guo L, Zhang L, Kuai X, Deng B, Pan Z, Li D, He F
J Proteome Res. 2008
PubMed ID: 18624398
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High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells.
Urbich C, Dernbach E, Rössig L, Zeiher AM, Dimmeler S
J Mol Cell Cardiol. 2008
PubMed ID: 18619973
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Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: role of its 5'-untranslated region.
Jean D, Rousselet N, Frade R
Biochem J. 2008
PubMed ID: 18366346
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Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment.
Abboud-Jarrous G, Atzmon R, Peretz T, Palermo C, Gadea BB, Joyce JA, Vlodavsky I
J Biol Chem. 2008
PubMed ID: 18450756
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Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen.
Puzer L, Barros NM, Paschoalin T, Hirata IY, Tanaka AS, Oliveira MC, Brömme D, Carmona AK
Biol Chem. 2008
PubMed ID: 18163891
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Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.
Herszényi L, Farinati F, Cardin R, István G, Molnár LD, Hritz I, De Paoli M, Plebani M, Tulassay Z
BMC Cancer. 2008
PubMed ID: 18616803
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The heavy-light chain loop of human cathepsin-L modulates its activity and stability.
Fairhead M, van der Walle CF
Protein Pept Lett. 2008
PubMed ID: 18221013
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Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
Kaletsky RL, Simmons G, Bates P
J Virol. 2007
PubMed ID: 17928356
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An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury.
Luke CJ, Pak SC, Askew YS, Naviglia TL, Askew DJ, Nobar SM, Vetica AC, Long OS, Watkins SC, Stolz DB, Barstead RJ, Moulder GL, Brömme D, Silverman GA
Cell. 2007
PubMed ID: 17889653
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Transcriptional upregulation of human cathepsin L by VEGF in glioblastoma cells.
Keerthivasan S, Keerthivasan G, Mittal S, Chauhan SS
Gene. 2007
PubMed ID: 17574778
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Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease.
Ljunggren A, Redzynia I, Alvarez-Fernandez M, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G
J Mol Biol. 2007
PubMed ID: 17561110
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Cathepsin L activity controls adipogenesis and glucose tolerance.
Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, Shi GP
Nat Cell Biol. 2007
PubMed ID: 17643114
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Proteolytic disassembly is a critical determinant for reovirus oncolysis.
Alain T, Kim TS, Lun X, Liacini A, Schiff LA, Senger DL, Forsyth PA
Mol Ther. 2007
PubMed ID: 17519890
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Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.
Macaulay IC, Tijssen MR, Thijssen-Timmer DC, Gusnanto A, Steward M, Burns P, Langford CF, Ellis PD, Dudbridge F, Zwaginga JJ, Watkins NA, van der Schoot CE, Ouwehand WH
Blood. 2007
PubMed ID: 17192395
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Interaction between human cathepsins K, L, and S and elastins: mechanism of elastinolysis and inhibition by macromolecular inhibitors.
Novinec M, Grass RN, Stark WJ, Turk V, Baici A, Lenarcic B
J Biol Chem. 2007
PubMed ID: 17227755
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The full-ORF clone resource of the German cDNA Consortium.
Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blöcker H, Heubner D, Hoerlein A, Michel G, Wedler H, Köhrer K, Ottenwälder B, Poustka A, Wiemann S, Schupp I
BMC Genomics. 2007
PubMed ID: 17974005
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Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice.
Sevenich L, Pennacchio LA, Peters C, Reinheckel T
Biol Chem. 2006
PubMed ID: 16913838
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Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.
Cheng T, Hitomi K, van Vlijmen-Willems IM, de Jongh GJ, Yamamoto K, Nishi K, Watts C, Reinheckel T, Schalkwijk J, Zeeuwen PL
J Biol Chem. 2006
PubMed ID: 16565075
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Significance of 32-kDa cathepsin L secreted from cancer cells.
Hashimoto Y, Kondo C, Kojima T, Nagata H, Moriyama A, Hayakawa T, Katunuma N
Cancer Biother Radiopharm. 2006
PubMed ID: 16918298
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Cathepsin L splice variants in human breast cell lines.
Caserman S, Kenig S, Sloane BF, Lah TT
Biol Chem. 2006
PubMed ID: 16740135
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Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases.
Bylaite M, Moussali H, Marciukaitiene I, Ruzicka T, Walz M
Exp Dermatol. 2006
PubMed ID: 16433682
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Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells.
Liu J, Sukhova GK, Yang JT, Sun J, Ma L, Ren A, Xu WH, Fu H, Dolganov GM, Hu C, Libby P, Shi GP
Atherosclerosis. 2006
PubMed ID: 15982660
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Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids.
Serveau-Avesque C, Martino MF, Hervé-Grépinet V, Hazouard E, Gauthier F, Diot E, Lalmanach G
Biol Cell. 2006
PubMed ID: 16354158
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Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD
J Proteome Res. 2005
PubMed ID: 16335952
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Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Urbich C, Heeschen C, Aicher A, Sasaki K, Bruhl T, Farhadi MR, Vajkoczy P, Hofmann WK, Peters C, Pennacchio LA, Abolmaali ND, Chavakis E, Reinheckel T, Zeiher AM, Dimmeler S
Nat Med. 2005
PubMed ID: 15665831
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Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T
DNA Res. 2005
PubMed ID: 16303743
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Cathepsins B and L and their inhibitors stefin B and cystatin C as markers for malignant progression of benign meningiomas.
Trinkaus M, Vranic A, Dolenc VV, Lah TT
Int J Biol Markers. 2005
PubMed ID: 15832773
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Immunohistochemical staining of cathepsins B, L and stefin A in human hypophysis and pituitary adenomas.
Strojnik T, Lah TT, Zidanik B
Anticancer Res. 2005
PubMed ID: 15816632
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The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.
Soukenik M, Diehl A, Leidert M, Sievert V, Büssow K, Leitner D, Labudde D, Ball LJ, Lechner A, Nägler DK, Oschkinat H
FEBS Lett. 2004
PubMed ID: 15498563
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
-
Soluble cathepsin-L: a marker of bone resorption and bone density?
Lang TH, Willinger U, Holzer G
J Lab Clin Med. 2004
PubMed ID: 15454886
-
Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells.
Wille A, Gerber A, Heimburg A, Reisenauer A, Peters C, Saftig P, Reinheckel T, Welte T, Bühling F
Biol Chem. 2004
PubMed ID: 15318816
-
Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes.
Zavasnik-Bergant V, Schweiger A, Bevec T, Golouh R, Turk V, Kos J
Immunology. 2004
PubMed ID: 15196205
-
DNA sequence and analysis of human chromosome 9.
Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG, Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Blöcker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I
Nature. 2004
PubMed ID: 15164053
-
Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance.
Michallet MC, Saltel F, Flacher M, Revillard JP, Genestier L
J Immunol. 2004
PubMed ID: 15100281
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.
Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A
Mol Cell. 2004
PubMed ID: 15099520
-
Comparison of expression of cathepsins B and L and MMP2 in endothelial cells and in capillary sprouting in collagen gel.
Caserman S, Lah TT
Int J Biol Markers. 2004
PubMed ID: 15255544
-
The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, Veenstra TD, Adkins JN, Pounds JG, Fagan R, Lobley A
Mol Cell Proteomics. 2004
PubMed ID: 14718574
-
Cathepsins B and L increased during response of periodontal ligament cells to mechanical stress in vitro.
Yamaguchi M, Ozawa Y, Nogimura A, Aihara N, Kojima T, Hirayama Y, Kasai K
Connect Tissue Res. 2004
PubMed ID: 15512772
-
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
-
Human proteoglycan testican-1 inhibits the lysosomal cysteine protease cathepsin L.
Bocock JP, Edgell CJ, Marr HS, Erickson AH
Eur J Biochem. 2003
PubMed ID: 14511383
-
Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.
Huang X, Vaag A, Carlsson E, Hansson M, Ahrén B, Groop L
Diabetes. 2003
PubMed ID: 12941783
-
Protein inhibitors form complexes with procathepsin L and augment cleavage of the propeptide.
Majerle A, Jerala R
Arch Biochem Biophys. 2003
PubMed ID: 12921779
-
Identification of interleukin-8 converting enzyme as cathepsin L.
Ohashi K, Naruto M, Nakaki T, Sano E
Biochim Biophys Acta. 2003
PubMed ID: 12818188
-
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis.
Welss T, Sun J, Irving JA, Blum R, Smith AI, Whisstock JC, Pike RN, von Mikecz A, Ruzicka T, Bird PI, Abts HF
Biochemistry. 2003
PubMed ID: 12809493
-
Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
Zhang H, Li XJ, Martin DB, Aebersold R
Nat Biotechnol. 2003
PubMed ID: 12754519
-
Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs.
Bania J, Gatti E, Lelouard H, David A, Cappello F, Weber E, Camosseto V, Pierre P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12748383
-
Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer.
Kayser K, Richter N, Hufnagl P, Kayser G, Kos J, Werle B
Anticancer Res. 2003
PubMed ID: 12926111
-
Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis.
Jayakumar A, Kang Y, Frederick MJ, Pak SC, Henderson Y, Holton PR, Mitsudo K, Silverman GA, EL-Naggar AK, Brömme D, Clayman GL
Arch Biochem Biophys. 2003
PubMed ID: 12504904
-
Kininogen-derived peptides for investigating the putative vasoactive properties of human cathepsins K and L.
Desmazes C, Galineau L, Gauthier F, Brömme D, Lalmanach G
Eur J Biochem. 2003
PubMed ID: 12492488
-
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
-
Functional consequences of cathepsin L deficiency in human lung epithelial cells.
Wille A, Heimburg A, Gerber A, Reisenauer A, Welte T, Bühling F
Biol Chem. 2002
PubMed ID: 12437119
-
Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages.
Schmid H, Sauerbrei R, Schwarz G, Weber E, Kalbacher H, Driessen C
Biol Chem. 2002
PubMed ID: 12437117
-
Identification and characterization of a novel human cathepsin L splice variant.
Arora S, Chauhan SS
Gene. 2002
PubMed ID: 12137950
-
Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy.
von Bülow R, Schmidt B, Dierks T, Schwabauer N, Schilling K, Weber E, Usón I, von Figura K
J Biol Chem. 2002
PubMed ID: 11777924
-
Decreased intracellular degradation of insulin-like growth factor binding protein-3 in cathepsin L-deficient fibroblasts.
Zwad O, Kübler B, Roth W, Scharf JG, Saftig P, Peters C, Braulke T
FEBS Lett. 2002
PubMed ID: 11801256
-
Splice variants of human cathepsin L mRNA show different expression rates.
Abudula A, Rommerskirch W, Weber E, Günther D, Wiederanders B
Biol Chem. 2001
PubMed ID: 11767948
-
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor.
Taggart CC, Lowe GJ, Greene CM, Mulgrew AT, O'Neill SJ, Levine RL, McElvaney NG
J Biol Chem. 2001
PubMed ID: 11435427
-
Role of the single cysteine residue, Cys 3, of human and bovine cystatin B (stefin B) in the inhibition of cysteine proteinases.
Pol E, Björk I
Protein Sci. 2001
PubMed ID: 11514663
-
Cathepsin L activity and its inhibitor in human otitis media.
Kusunoki T, Nishida S, Murata K, Kobashi K, Nakatani H, Hiwasa T, Tomura T
J Otolaryngol. 2001
PubMed ID: 11771045
-
Cathepsin L, but not cathepsin B, is a potential kininogenase.
Desmazes C, Gauthier F, Lalmanach G
Biol Chem. 2001
PubMed ID: 11517935
-
Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity.
Bertenshaw GP, Turk BE, Hubbard SJ, Matters GL, Bylander JE, Crisman JM, Cantley LC, Bond JS
J Biol Chem. 2001
PubMed ID: 11278902
-
Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing.
Dahl SW, Halkier T, Lauritzen C, Dolenc I, Pedersen J, Turk V, Turk B
Biochemistry. 2001
PubMed ID: 11327826
-
Characterization and comparative mapping of the porcine CTSL gene indicates a novel synteny between HSA9q21-->q22 and SSC10q11-->q12.
Spötter A, Drögemüller C, Kuiper H, Brenig B, Leeb T, Distl O
Cytogenet Cell Genet. 2001
PubMed ID: 11978977
-
Secreted cathepsin L generates endostatin from collagen XVIII.
Felbor U, Dreier L, Bryant RA, Ploegh HL, Olsen BR, Mothes W
EMBO J. 2000
PubMed ID: 10716919
-
Expression of cathepsins B and L in human lung epithelial cells is regulated by cytokines.
Gerber A, Welte T, Ansorge S, Bühling F
Adv Exp Med Biol. 2000
PubMed ID: 10849756
-
Cathepsin L is capable of truncating cystatin C of 11 N-terminal amino acids.
Popovic T, Cimerman N, Dolenc I, Ritonja A, Brzin J
FEBS Lett. 1999
PubMed ID: 10428479
-
Cathepsin expression during skeletal development.
Söderström M, Salminen H, Glumoff V, Kirschke H, Aro H, Vuorio E
Biochim Biophys Acta. 1999
PubMed ID: 10395917
-
Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.
Guncar G, Pungercic G, Klemencic I, Turk V, Turk D
EMBO J. 1999
PubMed ID: 10022822
-
Conformational studies on the specific cleavage site of Type I collagen (alpha-1) fragment (157-192) by cathepsins K and L by proton NMR spectroscopy.
Nosaka AY, Kanaori K, Teno N, Togame H, Inaoka T, Takai M, Kokubo T
Bioorg Med Chem. 1999
PubMed ID: 10218831
-
Cleavage of RXRalpha by a lysosomal enzyme, cathepsin L-type protease.
Nomura Y, Nagaya T, Yamaguchi S, Katunuma N, Seo H
Biochem Biophys Res Commun. 1999
PubMed ID: 9918848
-
Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action.
Nagaya T, Murata Y, Yamaguchi S, Nomura Y, Ohmori S, Fujieda M, Katunuma N, Yen PM, Chin WW, Seo H
J Biol Chem. 1998
PubMed ID: 9837884
-
Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor.
Ni J, Fernandez MA, Danielsson L, Chillakuru RA, Zhang J, Grubb A, Su J, Gentz R, Abrahamson M
J Biol Chem. 1998
PubMed ID: 9733783
-
Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells.
Halfon S, Ford J, Foster J, Dowling L, Lucian L, Sterling M, Xu Y, Weiss M, Ikeda M, Liggett D, Helms A, Caux C, Lebecque S, Hannum C, Menon S, McClanahan T, Gorman D, Zurawski G
J Biol Chem. 1998
PubMed ID: 9632704
-
The role of Gly-4 of human cystatin A (stefin A) in the binding of target proteinases. Characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4 mutants with papain, cathepsin B, and cathepsin L.
Estrada S, Nycander M, Hill NJ, Craven CJ, Waltho JP, Björk I
Biochemistry. 1998
PubMed ID: 9585570
-
Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis.
Schick C, Pemberton PA, Shi GP, Kamachi Y, Cataltepe S, Bartuski AJ, Gornstein ER, Brömme D, Chapman HA, Silverman GA
Biochemistry. 1998
PubMed ID: 9548757
-
Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro.
Ménard R, Carmona E, Takebe S, Dufour E, Plouffe C, Mason P, Mort JS
J Biol Chem. 1998
PubMed ID: 9468501
-
The crystal structure of human cathepsin L complexed with E-64.
Fujishima A, Imai Y, Nomura T, Fujisawa Y, Yamamoto Y, Sugawara T
FEBS Lett. 1997
PubMed ID: 9141479
-
Identification of peptide fragments generated by digestion of bovine and human osteocalcin with the lysosomal proteinases cathepsin B, D, L, H, and S.
Baumgrass R, Williamson MK, Price PA
J Bone Miner Res. 1997
PubMed ID: 9076588
-
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
Coulombe R, Grochulski P, Sivaraman J, Ménard R, Mort JS, Cygler M
EMBO J. 1996
PubMed ID: 8896443
-
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
-
Simultaneous isolation of human kidney cathepsins B, H, L and C and their characterisation.
Popovic T, Puizdar V, Ritonja A, Brzin J
J Chromatogr B Biomed Appl. 1996
PubMed ID: 8811434
-
Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L.
Bevec T, Stoka V, Pungercic G, Dolenc I, Turk V
J Exp Med. 1996
PubMed ID: 8666891
-
Cloning, genomic organization, and chromosomal localization of human cathepsin L.
Chauhan SS, Popescu NC, Ray D, Fleischmann R, Gottesman MM, Troen BR
J Biol Chem. 1993
PubMed ID: 8419312
-
Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L.
Goretzki L, Schmitt M, Mann K, Calvete J, Chucholowski N, Kramer M, Günzler WA, Jänicke F, Graeff H
FEBS Lett. 1992
PubMed ID: 1551416
-
Thyroglobulin processing by thyroidal proteases. Major sites of cleavage by cathepsins B, D, and L.
Dunn AD, Crutchfield HE, Dunn JT
J Biol Chem. 1991
PubMed ID: 1939080
-
Comparison of cathepsin L synthesized by normal and transformed cells at the gene, message, protein, and oligosaccharide levels.
Stearns NA, Dong JM, Pan JX, Brenner DA, Sahagian GG
Arch Biochem Biophys. 1990
PubMed ID: 2275556
-
Isolation and sequence of a cDNA for human pro-(cathepsin L).
Gal S, Gottesman MM
Biochem J. 1988
PubMed ID: 3421948
-
Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts.
Joseph LJ, Chang LC, Stamenkovich D, Sukhatme VP
J Clin Invest. 1988
PubMed ID: 2835398
-
Amino acid sequences of the human kidney cathepsins H and L.
Ritonja A, Popović T, Kotnik M, Machleidt W, Turk V
FEBS Lett. 1988
PubMed ID: 3342889
-
The major ras induced protein in NIH3T3 cells is cathepsin L.
Joseph L, Lapid S, Sukhatme V
Nucleic Acids Res. 1987
PubMed ID: 3550705
-
The N-terminal amino acid sequences of the heavy and light chains of human cathepsin L. Relationship to a cDNA clone for a major cysteine proteinase from a mouse macrophage cell line.
Mason RW, Walker JE, Northrop FD
Biochem J. 1986
PubMed ID: 3545185
-
Cathepsin L inactivates alpha 1-proteinase inhibitor by cleavage in the reactive site region.
Johnson DA, Barrett AJ, Mason RW
J Biol Chem. 1986
PubMed ID: 3490478
-
Action of rat liver cathepsin L on glucagon.
Kärgel HJ, Dettmer R, Etzold G, Kirschke H, Bohley P, Langner J
Acta Biol Med Ger. 1981
PubMed ID: 7340337
-
Effect of delta 9-tetrahydrocannabinol (THC) on female reproductive function.
Smith CG, Smith MT, Besch NF, Smith RG, Asch RH
Adv Biosci. 1978
PubMed ID: 116880
No mouse phenotype links available for this gene.
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