CSF1

Summary Top Help

Gene Description:

colony stimulating factor 1 (macrophage)

Synonyms:

MCSF, Csfm, CSF-1, CSF1, C87615, op, Csf1

Orthologs:

Human CSF1 (protein-coding), Mouse Csf1 (protein-coding), Rat Csf1 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Mouse: 1 Rat: 2

Linkage Regions: 2 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Iddm3	Rat	chr2:197256223..242256223	45.00	281
Idd18.2	Mouse	chr3:100949733..108222063	7.27	118

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm26	Rat	chr2:181710214..222281918	40.57	425

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr1:110452864..110473616 (20.75 kb) View in Genome Browser

(Mouse) NCBIM37 - chr3:107543966..107563387 (19.42 kb) View in Genome Browser

(Rat) RGSC3.4 - chr2:203292765..203307968 (15.20 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CSF1:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CSF1:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 4

Biocarta: 5

Reactome: None available

NCI-Nature Pathway Interaction Database: 3

Gene Ontology: 41

Positive regulation of cell-matrix adhesion	GO:0001954
Developmental process involved in reproduction	GO:0003006
Cytokine activity	GO:0005125
Macrophage colony-stimulating factor receptor binding	GO:0005157
Extracellular region	GO:0005576
Extracellular space	GO:0005615
Plasma membrane	GO:0005886
Inflammatory response	GO:0006954
Growth factor activity	GO:0008083
Cell proliferation	GO:0008283
Positive regulation of cell proliferation	GO:0008284
Positive regulation of gene expression	GO:0010628
Regulation of macrophage derived foam cell differentiation	GO:0010743
Positive regulation of macrophage derived foam cell differentiation	GO:0010744
Membrane	GO:0016020
Integral to membrane	GO:0016021
Hemopoiesis	GO:0030097
Cell differentiation	GO:0030154
Macrophage differentiation	GO:0030225
Regulation of ossification	GO:0030278
Osteoclast differentiation	GO:0030316
Positive regulation of cell migration	GO:0030335
Positive regulation of cellular protein metabolic process	GO:0032270
Positive regulation of mononuclear cell proliferation	GO:0032946
Positive regulation of multicellular organism growth	GO:0040018
Monocyte activation	GO:0042117
Odontogenesis	GO:0042476
Positive regulation of odontogenesis of dentin-containing tooth	GO:0042488
Protein homodimerization activity	GO:0042803
Receptor complex	GO:0043235
Innate immune response	GO:0045087
Positive regulation of macrophage differentiation	GO:0045651
Positive regulation of monocyte differentiation	GO:0045657
Positive regulation of osteoclast differentiation	GO:0045672
Positive regulation of protein kinase activity	GO:0045860
Positive regulation of Ras protein signal transduction	GO:0046579
Perinuclear region of cytoplasm	GO:0048471
Homeostasis of number of cells within a tissue	GO:0048873
Branching involved in mammary gland duct morphogenesis	GO:0060444
Mammary gland fat development	GO:0060611
Mammary duct terminal end bud growth	GO:0060763

Publications from PubMed Top Help

Type 1 Diabetes Publications: 2

Publications: 521

Autocrine CSF-1 and CSF-1 receptor coexpression promotes renal cell carcinoma growth.
Menke J, Kriegsmann J, Schimanski CC, Schwartz MM, Schwarting A, Kelley VR
Cancer Res. 2012
PubMed ID: 22052465
Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects.
Harris SE, MacDougall M, Horn D, Woodruff K, Zimmer SN, Rebel VI, Fajardo R, Feng JQ, Gluhak-Heinrich J, Harris MA, Abboud Werner S
Bone. 2012
PubMed ID: 21958845
Flt3 signaling-dependent dendritic cells protect against atherosclerosis.
Choi JH, Cheong C, Dandamudi DB, Park CG, Rodriguez A, Mehandru S, Velinzon K, Jung IH, Yoo JY, Oh GT, Steinman RM
Immunity. 2011
PubMed ID: 22078798
Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8.
Ivashkiv LB, Zhao B, Park-Min KH, Takami M
Ann N Y Acad Sci. 2011
PubMed ID: 22082370
Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization.
Miyamoto K, Yoshida S, Kawasumi M, Hashimoto K, Kimura T, Sato Y, Kobayashi T, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Hao W, Morioka H, Chiba K, Kobayashi T, Yasuda H, Penninger JM, Toyama Y, Suda T, Miyamoto T
J Exp Med. 2011
PubMed ID: 22006978
In situ proliferation and differentiation of macrophages in dental pulp.
Iwasaki Y, Otsuka H, Yanagisawa N, Hisamitsu H, Manabe A, Nonaka N, Nakamura M
Cell Tissue Res. 2011
PubMed ID: 21922246
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela T, Zarkada G, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, Alitalo K
Nat Cell Biol. 2011
PubMed ID: 21909098
Distinct roles of CSF-1 isoforms in lupus nephritis.
Menke J, Iwata Y, Rabacal WA, Basu R, Stanley ER, Kelley VR
J Am Soc Nephrol. 2011
PubMed ID: 21885670
CSF1 expression in nongynecological leiomyosarcoma is associated with increased tumor angiogenesis.
Espinosa I, Edris B, Lee CH, Cheng HW, Gilks CB, Wang Y, Montgomery KD, Varma S, Li R, Marinelli RJ, West RB, Nielsen T, Beck AH, van de Rijn M
Am J Pathol. 2011
PubMed ID: 21854753
Efficient differentiation and function of human macrophages in humanized CSF-1 mice.
Rathinam C, Poueymirou WT, Rojas J, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rongvaux A, Eynon EE, Manz MG, Flavell RA
Blood. 2011
PubMed ID: 21791433
Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1.
Tagliani E, Shi C, Nancy P, Tay CS, Pamer EG, Erlebacher A
J Exp Med. 2011
PubMed ID: 21825019
Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury.
Radi ZA, Koza-Taylor PH, Bell RR, Obert LA, Runnels HA, Beebe JS, Lawton MP, Sadis S
Am J Pathol. 2011
PubMed ID: 21703406
Role of macrophage colony-stimulating factor in polymicrobial sepsis according to studies using osteopetrotic (op/op) mice.
Ogiku M, Kono H, Ishii K, Hosomura N, Fujii H
J Surg Res. 2011
PubMed ID: 20189586
Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells.
Aligeti S, Kirma NB, Binkley PA, Schenken RS, Tekmal RR
Fertil Steril. 2011
PubMed ID: 21481374
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.
the Genetic Determinants of Paget's Disease (GDPD) Consortium, Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes JD, Ratajczak T, Rea SL, Rendina D, Gonzalez-Sarmiento R, Di Stefano M, Ward LC, Walsh JP, Ralston SH
Nat Genet. 2011
PubMed ID: 21623375
Bone marrow-derived cells serve as proangiogenic macrophages but not endothelial cells in wound healing.
Okuno Y, Nakamura-Ishizu A, Kishi K, Suda T, Kubota Y
Blood. 2011
PubMed ID: 21411758
Macrophages counteract demyelination in a mouse model of globoid cell leukodystrophy.
Kondo Y, Adams JM, Vanier MT, Duncan ID
J Neurosci. 2011
PubMed ID: 21389217
Impaired vibration of auditory ossicles in osteopetrotic mice.
Kanzaki S, Takada Y, Niida S, Takeda Y, Udagawa N, Ogawa K, Nango N, Momose A, Matsuo K
Am J Pathol. 2011
PubMed ID: 21356377
Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke.
Sugiyama Y, Yagita Y, Oyama N, Terasaki Y, Omura-Matsuoka E, Sasaki T, Kitagawa K
Stroke. 2011
PubMed ID: 21257824
Dendritic cell-specific ICAM-3-grabbing nonintegrin expression on M2-polarized and tumor-associated macrophages is macrophage-CSF dependent and enhanced by tumor-derived IL-6 and IL-10.
Domínguez-Soto A, Sierra-Filardi E, Puig-Kröger A, Pérez-Maceda B, Gómez-Aguado F, Corcuera MT, Sánchez-Mateos P, Corbí AL
J Immunol. 2011
PubMed ID: 21239715
CSF-1-dependent red pulp macrophages regulate CD4 T cell responses.
Kurotaki D, Kon S, Bae K, Ito K, Matsui Y, Nakayama Y, Kanayama M, Kimura C, Narita Y, Nishimura T, Iwabuchi K, Mack M, van Rooijen N, Sakaguchi S, Uede T, Morimoto J
J Immunol. 2011
PubMed ID: 21239712
Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits.
Erblich B, Zhu L, Etgen AM, Dobrenis K, Pollard JW
PLoS One. 2011
PubMed ID: 22046273
The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages.
Lee AW
PLoS One. 2011
PubMed ID: 22028782
Liver regeneration is impaired in macrophage colony stimulating factor deficient mice after partial hepatectomy: the role of M-CSF-induced macrophages.
Amemiya H, Kono H, Fujii H
J Surg Res. 2011
PubMed ID: 20031174
The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes.
Chung PY, Beyens G, Boonen S, Papapoulos S, Geusens P, Karperien M, Vanhoenacker F, Verbruggen L, Fransen E, Van Offel J, Goemaere S, Zmierczak HG, Westhovens R, Devogelaer JP, Van Hul W
Hum Genet. 2010
PubMed ID: 20839008
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
Eda H, Zhang J, Keith RH, Michener M, Beidler DR, Monahan JB
Cytokine. 2010
PubMed ID: 20829061
Macrophage-colony stimulating factor as an inducer of microglial proliferation in axotomized rat facial nucleus.
Yamamoto S, Nakajima K, Kohsaka S
J Neurochem. 2010
PubMed ID: 20831658
Technical Advance: The rat aorta contains resident mononuclear phagocytes with proliferative capacity and proangiogenic properties.
Zorzi P, Aplin AC, Smith KD, Nicosia RF
J Leukoc Biol. 2010
PubMed ID: 20628067
[The influence of fluoride on expression of OPGL and M-CSF genes and their proteins in rats with experimental fluorosis and the therapeutic effect of Danlan Xianpeng Liaofu caspule].
Sun XJ, Yu YN, Xiao YM
Zhonghua Bing Li Xue Za Zhi. 2010
PubMed ID: 21176538
Exploring the relationship of macrophage colony-stimulating factor levels on neuroaxonal metabolism and cognition during chronic human immunodeficiency virus infection.
Lentz MR, Degaonkar M, Mohamed MA, Kim H, Conant K, Halpern EF, Sacktor N, Barker PB, Pomper MG
J Neurovirol. 2010
PubMed ID: 20839921
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
Am J Obstet Gynecol. 2010
PubMed ID: 20673868
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts.
Knapek K, Frondorf K, Post J, Short S, Cox D, Gomez-Cambronero J
Mol Cell Biol. 2010
PubMed ID: 20647543
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.
Wei S, Nandi S, Chitu V, Yeung YG, Yu W, Huang M, Williams LT, Lin H, Stanley ER
J Leukoc Biol. 2010
PubMed ID: 20504948
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction.
Fantin A, Vieira JM, Gestri G, Denti L, Schwarz Q, Prykhozhij S, Peri F, Wilson SW, Ruhrberg C
Blood. 2010
PubMed ID: 20404134
NFAT regulates CSF-1 gene transcription triggered by L-selectin crosslinking.
Chen C, Cui L, Shang X, Zeng X
Biocell. 2010
PubMed ID: 20925194
Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation.
Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE
Stem Cells. 2010
PubMed ID: 20572009
Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.
Wang Y, Fu W, Xie F, Wang Y, Chu X, Wang H, Shen M, Wang Y, Wang Y, Sun W, Lei R, Yang L, Wu H, Foo J, Liu J, Jin L, Huang W
J Hum Genet. 2010
PubMed ID: 20485444
Macrophage colony-stimulating factor (M-CSF) in plasma and CSF of patients with mild cognitive impairment and Alzheimer's disease.
Laske C, Stransky E, Hoffmann N, Maetzler W, Straten G, Eschweiler GW, Leyhe T
Curr Alzheimer Res. 2010
PubMed ID: 20455868
Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis.
Shaposhnik Z, Wang X, Lusis AJ
J Lipid Res. 2010
PubMed ID: 20194110
Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone.
Albagha OM, Visconti MR, Alonso N, Langston AL, Cundy T, Dargie R, Dunlop MG, Fraser WD, Hooper MJ, Isaia G, Nicholson GC, del Pino Montes J, Gonzalez-Sarmiento R, di Stefano M, Tenesa A, Walsh JP, Ralston SH
Nat Genet. 2010
PubMed ID: 20436471
Transcriptional effects of colony-stimulating factor-1 in mouse macrophages.
El Chartouni C, Benner C, Eigner M, Lichtinger M, Rehli M
Immunobiology. 2010
PubMed ID: 19758725
Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.
Romero R, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Chaiworapongsa T, Pearce BD, Friel LA, Bartlett J, Anant MK, Salisbury BA, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
Am J Obstet Gynecol. 2010
PubMed ID: 20452482
Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas.
Bender AM, Collier LS, Rodriguez FJ, Tieu C, Larson JD, Halder C, Mahlum E, Kollmeyer TM, Akagi K, Sarkar G, Largaespada DA, Jenkins RB
Cancer Res. 2010
PubMed ID: 20388773
Elevated levels of macrophage colony-stimulating factor in human fracture healing.
Sarahrudi K, Mousavi M, Thomas A, Eipeldauer S, Vécsei V, Pietschmann P, Aharinejad S
J Orthop Res. 2010
PubMed ID: 19950360
Mouse models for breast cancer metastasis.
Kim IS, Baek SH
Biochem Biophys Res Commun. 2010
PubMed ID: 20230796
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes Immun. 2010
PubMed ID: 20237496
Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells.
Sanuki R, Shionome C, Kuwabara A, Mitsui N, Koyama Y, Suzuki N, Zhang F, Shimizu N, Maeno M
Connect Tissue Res. 2010
PubMed ID: 20001844
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma.
Abraham D, Zins K, Sioud M, Lucas T, Schäfer R, Stanley ER, Aharinejad S
Int J Cancer. 2010
PubMed ID: 19711348
Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation.
Ortega N, Wang K, Ferrara N, Werb Z, Vu TH
Dis Model Mech. 2010
PubMed ID: 20142327
Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.
Kim JH, Kim K, Jin HM, Song I, Youn BU, Lee SH, Choi Y, Kim N
J Biol Chem. 2010
PubMed ID: 20037154
Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae.
Lai JF, Zindl CL, Duffy LB, Atkinson TP, Jung YW, van Rooijen N, Waites KB, Krause DC, Chaplin DD
PLoS One. 2010
PubMed ID: 21203444
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)
PLoS Genet. 2010
PubMed ID: 20628624
Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.
Kim HJ, Alonzo ES, Dorothee G, Pollard JW, Sant'Angelo DB
PLoS One. 2010
PubMed ID: 20625428
Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury.
Marumo T, Hishikawa K, Yoshikawa M, Hirahashi J, Kawachi S, Fujita T
Am J Physiol Renal Physiol. 2010
PubMed ID: 19906951
Circulating level of macrophage colony-stimulating factor can be predictive for human in vitro fertilization outcome.
Salmassi A, Mettler L, Jonat W, Buck S, Koch K, Schmutzler AG
Fertil Steril. 2010
PubMed ID: 18996518
A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion.
Jensen JR, Witz CA, Schenken RS, Tekmal RR
Fertil Steril. 2010
PubMed ID: 18990370
Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor.
Patsialou A, Wyckoff J, Wang Y, Goswami S, Stanley ER, Condeelis JS
Cancer Res. 2009
PubMed ID: 19934330
Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis.
Menke J, Rabacal WA, Byrne KT, Iwata Y, Schwartz MM, Stanley ER, Schwarting A, Kelley VR
J Am Soc Nephrol. 2009
PubMed ID: 19926892
Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections.
Gartland A, Mason-Savas A, Yang M, MacKay CA, Birnbaum MJ, Odgren PR
Am J Pathol. 2009
PubMed ID: 19893052
Nonhemopoietic cell TLR4 signaling is critical in causing early lipopolysaccharide-induced ileus.
Buchholz BM, Chanthaphavong RS, Bauer AJ
J Immunol. 2009
PubMed ID: 19846874
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Phosphatidylinositol 3 kinase/Akt signal relay cooperates with smad in bone morphogenetic protein-2-induced colony stimulating factor-1 (CSF-1) expression and osteoclast differentiation.
Mandal CC, Ghosh Choudhury G, Ghosh-Choudhury N
Endocrinology. 2009
PubMed ID: 19819979
Colony-stimulating factor-1 (CSF-1) directly inhibits receptor activator of nuclear factor-{kappa}B ligand (RANKL) expression by osteoblasts.
Wittrant Y, Gorin Y, Mohan S, Wagner B, Abboud-Werner SL
Endocrinology. 2009
PubMed ID: 19819976
Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages.
Dovas A, Gevrey JC, Grossi A, Park H, Abou-Kheir W, Cox D
J Cell Sci. 2009
PubMed ID: 19808890
M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.
Jack GD, Zhang L, Friedman AD
Blood. 2009
PubMed ID: 19587381
GM-CSF regulates fusion of mononuclear osteoclasts into bone-resorbing osteoclasts by activating the Ras/ERK pathway.
Lee MS, Kim HS, Yeon JT, Choi SW, Chun CH, Kwak HB, Oh J
J Immunol. 2009
PubMed ID: 19641137
Selective reduction in microglia density and function in the white matter of colony-stimulating factor-1-deficient mice.
Kondo Y, Duncan ID
J Neurosci Res. 2009
PubMed ID: 19396881
Phosphatidylinostitol-3 kinase and phospholipase C enhance CSF-1-dependent macrophage survival by controlling glucose uptake.
Chang M, Hamilton JA, Scholz GM, Masendycz P, Macaulay SL, Elsegood CL
Cell Signal. 2009
PubMed ID: 19376223
The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.
Cammer M, Gevrey JC, Lorenz M, Dovas A, Condeelis J, Cox D
J Biol Chem. 2009
PubMed ID: 19561083
Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation.
Yagiz K, Rittling SR
Exp Cell Res. 2009
PubMed ID: 19427849
CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice.
Menke J, Iwata Y, Rabacal WA, Basu R, Yeung YG, Humphreys BD, Wada T, Schwarting A, Stanley ER, Kelley VR
J Clin Invest. 2009
PubMed ID: 19587445
MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells.
Sarrazin S, Mossadegh-Keller N, Fukao T, Aziz A, Mourcin F, Vanhille L, Kelly Modis L, Kastner P, Chan S, Duprez E, Otto C, Sieweke MH
Cell. 2009
PubMed ID: 19632180
Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine.
Huynh D, Dai XM, Nandi S, Lightowler S, Trivett M, Chan CK, Bertoncello I, Ramsay RG, Stanley ER
Gastroenterology. 2009
PubMed ID: 19303020
Renal epithelial cell-derived monocyte colony stimulating factor as a local informant of renal injury and means of monocyte activation.
Singh KA, Kampen RL, Hoffmann SC, Eldaif SM, Kirk AD
Transpl Int. 2009
PubMed ID: 19196448
Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor prognosis in gynecological and nongynecological leiomyosarcoma.
Espinosa I, Beck AH, Lee CH, Zhu S, Montgomery KD, Marinelli RJ, Ganjoo KN, Nielsen TO, Gilks CB, West RB, van de Rijn M
Am J Pathol. 2009
PubMed ID: 19443701
A High-Density Association Study of 383 Candidate Genes for Volumetric Bone Density at the Femoral Neck and Lumbar Spine among Older Men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, for the MrOS Research Group
J Bone Miner Res. 2009
PubMed ID: 19453261
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis.
Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T
J Exp Med. 2009
PubMed ID: 19398755
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors.
Kawamura K, Komohara Y, Takaishi K, Katabuchi H, Takeya M
Pathol Int. 2009
PubMed ID: 19432671
Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal.
Oatley JM, Oatley MJ, Avarbock MR, Tobias JW, Brinster RL
Development. 2009
PubMed ID: 19270176
Targeted overexpression of the two colony-stimulating factor-1 isoforms in osteoblasts differentially affects bone loss in ovariectomized mice.
Yao GQ, Wu JJ, Ovadia S, Troiano N, Sun BH, Insogna K
Am J Physiol Endocrinol Metab. 2009
PubMed ID: 19141689
The molecular signature of spermatogonial stem/progenitor cells in the 6-day-old mouse testis.
Kokkinaki M, Lee TL, He Z, Jiang J, Golestaneh N, Hofmann MC, Chan WY, Dym M
Biol Reprod. 2009
PubMed ID: 19109221
Expression of macrophage colony-stimulating factor (M-CSF) and its receptor in streptozotocin-induced diabetic rats.
Liu W, Xu GZ, Jiang CH, Da CD
Curr Eye Res. 2009
PubMed ID: 19219684
IL-4 blocks M-CSF-dependent macrophage proliferation by inducing p21Waf1 in a STAT6-dependent way.
Arpa L, Valledor AF, Lloberas J, Celada A
Eur J Immunol. 2009
PubMed ID: 19130475
C-reactive protein induces M-CSF release and macrophage proliferation.
Devaraj S, Yun JM, Duncan-Staley C, Jialal I
J Leukoc Biol. 2009
PubMed ID: 19008293
Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages.
Irvine KM, Andrews MR, Fernandez-Rojo MA, Schroder K, Burns CJ, Su S, Wilks AF, Parton RG, Hume DA, Sweet MJ
J Leukoc Biol. 2009
PubMed ID: 19004987
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation.
Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19109434
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth.
Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J, Lang RA, Pollard JW
PLoS One. 2009
PubMed ID: 19668347
Colony-stimulating factor-1-dependent macrophage functions regulate the maternal decidua immune responses against Listeria monocytogenes infections during early gestation in mice.
Qiu X, Zhu L, Pollard JW
Infect Immun. 2009
PubMed ID: 18852237
Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
Papakonstanti EA, Zwaenepoel O, Bilancio A, Burns E, Nock GE, Houseman B, Shokat K, Ridley AJ, Vanhaesebroeck B
J Cell Sci. 2008
PubMed ID: 19033389
Receptor activator of nuclear factor-kappa B ligand induces osteoclast formation in RAW 264.7 macrophage cells via augmented production of macrophage-colony-stimulating factor.
Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Yoshida T, Yokochi T
Microbiol Immunol. 2008
PubMed ID: 19120972
Clinical use of colony-stimulating factor-1 in ovulation induction for poor responders.
Takasaki A, Ohba T, Okamura Y, Honda R, Seki M, Tanaka N, Okamura H
Fertil Steril. 2008
PubMed ID: 18718581
Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Chen X, Liu H, Focia PJ, Shim AH, He X
Proc Natl Acad Sci U S A. 2008
PubMed ID: 19017797
Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice.
Menke J, Hsu MY, Byrne KT, Lucas JA, Rabacal WA, Croker BP, Zong XH, Stanley ER, Kelley VR
J Immunol. 2008
PubMed ID: 18981160
IFN-{gamma}-mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation.
Valledor AF, Arpa L, Sánchez-Tilló E, Comalada M, Casals C, Xaus J, Caelles C, Lloberas J, Celada A
Blood. 2008
PubMed ID: 18682602
Increased macrophage colony-stimulating factor levels in patients with Graves' disease.
Morishita E, Sekiya A, Hayashi T, Kadohira Y, Maekawa M, Yamazaki M, Asakura H, Nakao S, Ohtake S
Int J Hematol. 2008
PubMed ID: 18751872
Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.
Achuthan A, Masendycz P, Lopez JA, Nguyen T, James DE, Sweet MJ, Hamilton JA, Scholz GM
Mol Cell Biol. 2008
PubMed ID: 18710945
Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies.
Douglass TG, Driggers L, Zhang JG, Hoa N, Delgado C, Williams CC, Dan Q, Sanchez R, Jeffes EW, Wepsic HT, Myers MP, Koths K, Jadus MR
Int Immunopharmacol. 2008
PubMed ID: 18687298
PIR-B-deficient mice are susceptible to Salmonella infection.
Torii I, Oka S, Hotomi M, Benjamin WH, Takai T, Kearney JF, Briles DE, Kubagawa H
J Immunol. 2008
PubMed ID: 18768880
VEGF and M-CSF levels in periodontal tissue during tooth movement.
Kaku M, Motokawa M, Tohma Y, Tsuka N, Koseki H, Sunagawa H, Arturo Marquez Hernandes R, Ohtani J, Fujita T, Kawata T, Tanne K
Biomed Res. 2008
PubMed ID: 18724005
The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer.
Zhou Y, Yi X, Stoffer JB, Bonafe N, Gilmore-Hebert M, McAlpine J, Chambers SK
Mol Cancer Res. 2008
PubMed ID: 18708368
Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung.
Skrzypski M, Jassem E, Taron M, Sanchez JJ, Mendez P, Rzyman W, Gulida G, Raz D, Jablons D, Provencio M, Massuti B, Chaib I, Perez-Roca L, Jassem J, Rosell R
Clin Cancer Res. 2008
PubMed ID: 18676750
Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor.
Rioja I, Hughes FJ, Sharp CH, Warnock LC, Montgomery DS, Akil M, Wilson AG, Binks MH, Dickson MC
Arthritis Rheum. 2008
PubMed ID: 18668547
L-selectin ligation-induced CSF-1 gene transcription is regulated by AP-1 in a c-Abl kinase-dependent manner.
Chen C, Shang X, Cui L, Xu T, Luo J, Ba X, Zeng X
Hum Immunol. 2008
PubMed ID: 18619508
Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation.
Aharinejad S, Abraham D, Paulus P, Zins K, Hofmann M, Michlits W, Gyöngyösi M, Macfelda K, Lucas T, Trescher K, Grimm M, Stanley ER
Cardiovasc Res. 2008
PubMed ID: 18436538
A special linker between macrophage and hematopoietic malignant cells: membrane form of macrophage colony-stimulating factor.
Wang L, Zheng GG, Ma CH, Lin YM, Zhang HY, Ma YY, Chong JH, Wu KF
Cancer Res. 2008
PubMed ID: 18632616
Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations.
Guerrini MM, Sobacchi C, Cassani B, Abinun M, Kilic SS, Pangrazio A, Moratto D, Mazzolari E, Clayton-Smith J, Orchard P, Coxon FP, Helfrich MH, Crockett JC, Mellis D, Vellodi A, Tezcan I, Notarangelo LD, Rogers MJ, Vezzoni P, Villa A, Frattini A
Am J Hum Genet. 2008
PubMed ID: 18606301
Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor.
Bonfield TL, Thomassen MJ, Farver CF, Abraham S, Koloze MT, Zhang X, Mosser DM, Culver DA
J Immunol. 2008
PubMed ID: 18566389
The prognostic impact of M-CSF, CSF-1 receptor, CD68 and CD3 in prostatic carcinoma.
Richardsen E, Uglehus RD, Due J, Busch C, Busund LT
Histopathology. 2008
PubMed ID: 18510570
Formation of osteoclast-like cells from peripheral blood of periodontitis patients occurs without supplementation of macrophage colony-stimulating factor.
Tjoa ST, de Vries TJ, Schoenmaker T, Kelder A, Loos BG, Everts V
J Clin Periodontol. 2008
PubMed ID: 18435789
Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells.
Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M
EMBO J. 2008
PubMed ID: 18511911
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.
Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit LA, Byers DE, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polineni D, Patterson GA, Schwendener RA, Allard JD, Peltz G, Holtzman MJ
Nat Med. 2008
PubMed ID: 18488036
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.
Lin H, Lee E, Hestir K, Leo C, Huang M, Bosch E, Halenbeck R, Wu G, Zhou A, Behrens D, Hollenbaugh D, Linnemann T, Qin M, Wong J, Chu K, Doberstein SK, Williams LT
Science. 2008
PubMed ID: 18467591
csf1 is required for early embryonic macrophage development: characterization of the csf1(op)/csf1(op) mutation in ES cell-derived macrophages.
Loureiro RM, Monaco KA, Kearney JB, Blickarz-Durand CE, Kirby SL, Inamdar MS, Bautch VL
Br J Haematol. 2008
PubMed ID: 18422785
Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis.
Higgins DM, Sanchez-Campillo J, Rosas-Taraco AG, Higgins JR, Lee EJ, Orme IM, Gonzalez-Juarrero M
J Immunol. 2008
PubMed ID: 18354213
Novel pro-survival functions of the Kruppel-like transcription factor Egr2 in promotion of macrophage colony-stimulating factor-mediated osteoclast survival downstream of the MEK/ERK pathway.
Bradley EW, Ruan MM, Oursler MJ
J Biol Chem. 2008
PubMed ID: 18198176
ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion.
Rovida E, Spinelli E, Sdelci S, Barbetti V, Morandi A, Giuntoli S, Dello Sbarba P
J Immunol. 2008
PubMed ID: 18322228
The critical role of the colony-stimulating factor-1 receptor in the differentiation of myeloblastic leukemia cells.
Hamilton JA, Whitty G, Masendycz P, Wilson NJ, Jackson J, De Nardo D, Scholz GM
Mol Cancer Res. 2008
PubMed ID: 18337452
Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1.
Zarebski A, Velu CS, Baktula AM, Bourdeau T, Horman SR, Basu S, Bertolone SJ, Horwitz M, Hildeman DA, Trent JO, Grimes HL
Immunity. 2008
PubMed ID: 18328744
Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus.
Ghia JE, Galeazzi F, Ford DC, Hogaboam CM, Vallance BA, Collins S
Am J Physiol Gastrointest Liver Physiol. 2008
PubMed ID: 18202111
M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo.
Curry JM, Eubank TD, Roberts RD, Wang Y, Pore N, Maity A, Marsh CB
PLoS ONE. 2008
PubMed ID: 18852899
Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages.
O'Mahony DS, Pham U, Iyer R, Hawn TR, Liles WC
Int J Med Sci. 2008
PubMed ID: 18219369
Circulating colony stimulating factor-1 and breast cancer risk.
Tamimi RM, Brugge JS, Freedman ML, Miron A, Iglehart JD, Colditz GA, Hankinson SE
Cancer Res. 2008
PubMed ID: 18172291
Macrophages driven to a novel state of activation have anti-inflammatory properties in mice.
Brem-Exner BG, Sattler C, Hutchinson JA, Koehl GE, Kronenberg K, Farkas S, Inoue S, Blank C, Knechtle SJ, Schlitt HJ, Fändrich F, Geissler EK
J Immunol. 2008
PubMed ID: 18097035
Molecular identification of COL6A3-CSF1 fusion transcripts in tenosynovial giant cell tumors.
Möller E, Mandahl N, Mertens F, Panagopoulos I
Genes Chromosomes Cancer. 2008
PubMed ID: 17918257
M-CSF: a novel plasmacytoid and conventional dendritic cell poietin.
Fancke B, Suter M, Hochrein H, O'Keeffe M
Blood. 2008
PubMed ID: 17916748
VEGF Restores Delayed Tumor Progression in Tumors Depleted of Macrophages.
Lin EY, Li JF, Bricard G, Wang W, Deng Y, Sellers R, Porcelli SA, Pollard JW
Mol Oncol. 2007
PubMed ID: 18509509
Antigen presenting cells treated in vitro by macrophage colony-stimulating factor and autoantigen protect mice from autoimmunity.
Guan Y, Yu S, Zhao Z, Ciric B, Zhang GX, Rostami A
J Neuroimmunol. 2007
PubMed ID: 18006080
Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism.
Hohensinner PJ, Kaun C, Rychli K, Niessner A, Pfaffenberger S, Rega G, de Martin R, Maurer G, Ullrich R, Huber K, Wojta J
J Thromb Haemost. 2007
PubMed ID: 17922812
CSF-1 and TPA stimulate independent pathways leading to lysosomal degradation or regulated intramembrane proteolysis of the CSF-1 receptor.
Glenn G, van der Geer P
FEBS Lett. 2007
PubMed ID: 17967422
Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner.
Horiuchi K, Miyamoto T, Takaishi H, Hakozaki A, Kosaki N, Miyauchi Y, Furukawa M, Takito J, Kaneko H, Matsuzaki K, Morioka H, Blobel CP, Toyama Y
J Immunol. 2007
PubMed ID: 17982061
ERK signaling regulates macrophage colony-stimulating factor expression induced by titanium particles in MC3T3.E1 murine calvarial preosteoblastic cells.
Seo SW, Lee D, Cho SK, Kim AD, Minematsu H, Celil Aydemir AB, Geller JA, Macaulay W, Yang J, Young-In Lee F
Ann N Y Acad Sci. 2007
PubMed ID: 18056041
Multiple roles of M-CSF in human osteoclastogenesis.
Hodge JM, Kirkland MA, Nicholson GC
J Cell Biochem. 2007
PubMed ID: 17516513
The protective effect of the vagus nerve in a murine model of chronic relapsing colitis.
Ghia JE, Blennerhassett P, El-Sharkawy RT, Collins SM
Am J Physiol Gastrointest Liver Physiol. 2007
PubMed ID: 17673544
Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF.
Zhang HH, Basu S, Wu F, Begley CG, Saris CJ, Dunn AR, Burgess AW, Walker F
J Leukoc Biol. 2007
PubMed ID: 17652450
Homeobox gene HLX1 is a regulator of colony stimulating factor-1 dependent trophoblast cell proliferation.
Rajaraman G, Murthi P, Leo B, Brennecke SP, Kalionis B
Placenta. 2007
PubMed ID: 17532041
Macrophage-colony stimulating factor in obese adipose tissue: studies with heterozygous op/+ mice.
Sugita S, Kamei Y, Oka J, Suganami T, Ogawa Y
Obesity (Silver Spring). 2007
PubMed ID: 17712116
M-CSF-mediated macrophage differentiation but not proliferation is correlated with increased and prolonged ERK activation.
Suzu S, Hiyoshi M, Yoshidomi Y, Harada H, Takeya M, Kimura F, Motoyoshi K, Okada S
J Cell Physiol. 2007
PubMed ID: 17443671
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation.
Fontana L, Pelosi E, Greco P, Racanicchi S, Testa U, Liuzzi F, Croce CM, Brunetti E, Grignani F, Peschle C
Nat Cell Biol. 2007
PubMed ID: 17589498
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Sasmono RT, Ehrnsperger A, Cronau SL, Ravasi T, Kandane R, Hickey MJ, Cook AD, Himes SR, Hamilton JA, Hume DA
J Leukoc Biol. 2007
PubMed ID: 17438263
Important roles for macrophage colony-stimulating factor, CC chemokine ligand 2, and mononuclear phagocytes in the pathogenesis of pulmonary fibrosis.
Baran CP, Opalek JM, McMaken S, Newland CA, O'Brien JM, Hunter MG, Bringardner BD, Monick MM, Brigstock DR, Stromberg PC, Hunninghake GW, Marsh CB
Am J Respir Crit Care Med. 2007
PubMed ID: 17431224
M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721.
Faccio R, Takeshita S, Colaianni G, Chappel J, Zallone A, Teitelbaum SL, Ross FP
J Biol Chem. 2007
PubMed ID: 17420256
c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages.
Takeshita S, Faccio R, Chappel J, Zheng L, Feng X, Weber JD, Teitelbaum SL, Ross FP
J Biol Chem. 2007
PubMed ID: 17420255
The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation.
Pakuts B, Debonneville C, Liontos LM, Loreto MP, McGlade CJ
J Biol Chem. 2007
PubMed ID: 17353186
Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages.
Voehringer D, van Rooijen N, Locksley RM
J Leukoc Biol. 2007
PubMed ID: 17339609
MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC
J Biol Chem. 2007
PubMed ID: 17403683
Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis.
Hibbs ML, Quilici C, Kountouri N, Seymour JF, Armes JE, Burgess AW, Dunn AR
J Immunol. 2007
PubMed ID: 17475873
Serum macrophage-colony stimulating factor levels in colorectal cancer patients correlate with lymph node metastasis and poor prognosis.
Mroczko B, Groblewska M, Wereszczyńska-Siemiatkowska U, Okulczyk B, Kedra B, Łaszewicz W, Dabrowski A, Szmitkowski M
Clin Chim Acta. 2007
PubMed ID: 17368603
Targeted expression of csCSF-1 in op/op mice ameliorates tooth defects.
Werner SA, Gluhak-Heinrich J, Woodruff K, Wittrant Y, Cardenas L, Roudier M, MacDougall M
Arch Oral Biol. 2007
PubMed ID: 17126805
Induction of dendritic cell-like phenotype in macrophages during foam cell formation.
Cho HJ, Shashkin P, Gleissner CA, Dunson D, Jain N, Lee JK, Miller Y, Ley K
Physiol Genomics. 2007
PubMed ID: 17244792
Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation.
Fleetwood AJ, Lawrence T, Hamilton JA, Cook AD
J Immunol. 2007
PubMed ID: 17404308
Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity.
Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT
J Bone Miner Res. 2007
PubMed ID: 17243865
Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice.
Ko EA, Amiri F, Pandey NR, Javeshghani D, Leibovitz E, Touyz RM, Schiffrin EL
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17142347
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors.
Wyckoff JB, Wang Y, Lin EY, Li JF, Goswami S, Stanley ER, Segall JE, Pollard JW, Condeelis J
Cancer Res. 2007
PubMed ID: 17363585
Differential regulation of colony stimulating factor 1 and macrophage migration inhibitory factor expression by inflammatory cytokines in term human decidua: implications for macrophage trafficking at the fetal-maternal interface.
Arcuri F, Buchwalder L, Toti P, Cintorino M, Tosi P, Lockwood CJ, Rybalov B, Schatz F
Biol Reprod. 2007
PubMed ID: 17108334
Colony-stimulating factor-1 increases osteoclast intracellular pH and promotes survival via the electroneutral Na/HCO3 cotransporter NBCn1.
Bouyer P, Sakai H, Itokawa T, Kawano T, Fulton CM, Boron WF, Insogna KL
Endocrinology. 2007
PubMed ID: 17068143
Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.
Ueki Y, Lin CY, Senoo M, Ebihara T, Agata N, Onji M, Saheki Y, Kawai T, Mukherjee PM, Reichenberger E, Olsen BR
Cell. 2007
PubMed ID: 17218256
Osteopetrotic (op/op) mice have reduced microglia, no Abeta deposition, and no changes in dopaminergic neurons.
Kondo Y, Lemere CA, Seabrook TJ
J Neuroinflammation. 2007
PubMed ID: 18093340
Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF.
Fujita K, Janz S
Mol Cancer. 2007
PubMed ID: 17971207
Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
Huang HY, Thuita L, Strickland P, Hoffman SC, Comstock GW, Helzlsouer KJ
BMC Genet. 2007
PubMed ID: 17355643
Serum levels of granulocyte colony-stimulating factor (G-CSF) and macrophage colony-stimulating factor (M-CSF) in pancreatic cancer patients.
Groblewska M, Mroczko B, Wereszczyńska-Siemiatkowska U, Myśliwiec P, Kedra B, Szmitkowski M
Clin Chem Lab Med. 2007
PubMed ID: 17243911
Macrophage colony stimulating factor is a crucial factor for the intrinsic macrophage response in mice heterozygously deficient for the myelin protein P0.
Müller M, Berghoff M, Kobsar I, Kiefer R, Martini R
Exp Neurol. 2007
PubMed ID: 16962581
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands.
Mullaly SC, Kubes P
J Immunol. 2006
PubMed ID: 17114491
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide.
Zhou H, Lapointe BM, Clark SR, Zbytnuik L, Kubes P
J Immunol. 2006
PubMed ID: 17114485
Macrophages regulate the angiogenic switch in a mouse model of breast cancer.
Lin EY, Li JF, Gnatovskiy L, Deng Y, Zhu L, Grzesik DA, Qian H, Xue XN, Pollard JW
Cancer Res. 2006
PubMed ID: 17114237
Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland.
Ingman WV, Wyckoff J, Gouon-Evans V, Condeelis J, Pollard JW
Dev Dyn. 2006
PubMed ID: 17029292
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Yang FC, Chen S, Robling AG, Yu X, Nebesio TD, Yan J, Morgan T, Li X, Yuan J, Hock J, Ingram DA, Clapp DW
J Clin Invest. 2006
PubMed ID: 17053831
Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.
Lee AW, States DJ
Cell Death Differ. 2006
PubMed ID: 16514418
Distinct in vivo roles of colony-stimulating factor-1 isoforms in renal inflammation.
Jang MH, Herber DM, Jiang X, Nandi S, Dai XM, Zeller G, Stanley ER, Kelley VR
J Immunol. 2006
PubMed ID: 16951369
Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells.
Alnaeeli M, Penninger JM, Teng YT
J Immunol. 2006
PubMed ID: 16920972
A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations.
Irvine KM, Burns CJ, Wilks AF, Su S, Hume DA, Sweet MJ
FASEB J. 2006
PubMed ID: 16877523
CSF1 gene associated with aggressive periodontitis in the Japanese population.
Rabello D, Soedarsono N, Kamei H, Ishihara Y, Noguchi T, Fuma D, Suzuki M, Sakaki Y, Yamaguchi A, Kojima T
Biochem Biophys Res Commun. 2006
PubMed ID: 16844084
Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes.
Sollars VE, Pequignot E, Rothstein JL, Buchberg AM
Mamm Genome. 2006
PubMed ID: 16897342
Concerted action of Smad and CREB-binding protein regulates bone morphogenetic protein-2-stimulated osteoblastic colony-stimulating factor-1 expression.
Ghosh-Choudhury N, Singha PK, Woodruff K, St Clair P, Bsoul S, Werner SL, Choudhury GG
J Biol Chem. 2006
PubMed ID: 16707491
Conditional deletion of the colony stimulating factor-1 receptor (c-fms proto-oncogene) in mice.
Li J, Chen K, Zhu L, Pollard JW
Genesis. 2006
PubMed ID: 16823860
Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice.
Bergmann CE, Hoefer IE, Meder B, Roth H, van Royen N, Breit SM, Jost MM, Aharinejad S, Hartmann S, Buschmann IR
J Leukoc Biol. 2006
PubMed ID: 16684892
The DNA sequence and biological annotation of human chromosome 1.
Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E
Nature. 2006
PubMed ID: 16710414
Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.
Paulus P, Stanley ER, Schäfer R, Abraham D, Aharinejad S
Cancer Res. 2006
PubMed ID: 16618760
Chemokine and chemokine receptor expression during colony stimulating factor-1-induced osteoclast differentiation in the toothless osteopetrotic rat: a key role for CCL9 (MIP-1gamma) in osteoclastogenesis in vivo and in vitro.
Yang M, Mailhot G, MacKay CA, Mason-Savas A, Aubin J, Odgren PR
Blood. 2006
PubMed ID: 16304045
Serum levels of macrophage colony-stimulating factor in singleton and twin pregnancy.
Hayashi M, Fukasawa I, Inaba N
Horm Metab Res. 2006
PubMed ID: 16673212
Langerhans cells arise from monocytes in vivo.
Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M
Nat Immunol. 2006
PubMed ID: 16444257
Colony-stimulating factor-1 in immunity and inflammation.
Chitu V, Stanley ER
Curr Opin Immunol. 2006
PubMed ID: 16337366
Involvement of CSF-1 in generating a stroma-independent hematopoietic stem cell line.
Heberlein C, Friel J, Itoh K, Medlock E, Li L, Nakayama N, Stocking C, Geldmacher M, Ostertag W
J Cell Physiol. 2006
PubMed ID: 16250018
The cell-surface isoform of colony stimulating factor 1 (CSF1) restores but does not completely normalize fecundity in CSF1-deficient mice.
Ovadia S, Insogna K, Yao GQ
Biol Reprod. 2006
PubMed ID: 16237150
Cellular and molecular mechanisms underlying LPS-associated myocyte impairment.
Tavener SA, Kubes P
Am J Physiol Heart Circ Physiol. 2006
PubMed ID: 16172157
A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells.
West RB, Rubin BP, Miller MA, Subramanian S, Kaygusuz G, Montgomery K, Zhu S, Marinelli RJ, De Luca A, Downs-Kelly E, Goldblum JR, Corless CL, Brown PO, Gilks CB, Nielsen TO, Huntsman D, van de Rijn M
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16407111
Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain.
Nandi S, Akhter MP, Seifert MF, Dai XM, Stanley ER
Blood. 2006
PubMed ID: 16210339
Effect of bacterial endotoxins on superovulated mouse embryos in vivo: is CSF-1 involved in endotoxin-induced pregnancy loss?
Jaiswal YK, Chaturvedi MM, Deb K
Infect Dis Obstet Gynecol. 2006
PubMed ID: 17485799
Genetic association study on colony-stimulating factor 1 in Alzheimer's disease.
Wollmer MA, Nitsch RM, Hock C, Papassotiropoulos A
Neurodegener Dis. 2006
PubMed ID: 17192722
Tubulointerstitial macrophage accumulation is regulated by sequentially expressed osteopontin and macrophage colony-stimulating factor: implication for the role of atorvastatin.
Tian S, Ding G, Jia R, Chu G
Mediators Inflamm. 2006
PubMed ID: 16883060
Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis.
Takasugi K, Yamamura M, Iwahashi M, Otsuka F, Yamana J, Sunahori K, Kawashima M, Yamada M, Makino H
Arthritis Res Ther. 2006
PubMed ID: 16859503
M-CSF induces the stable interaction of cFms with alphaVbeta3 integrin in osteoclasts.
Elsegood CL, Zhuo Y, Wesolowski GA, Hamilton JA, Rodan GA, Duong le T
Int J Biochem Cell Biol. 2006
PubMed ID: 16600665
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge.
Lomas-Neira J, Chung CS, Perl M, Gregory S, Biffl W, Ayala A
Am J Physiol Lung Cell Mol Physiol. 2006
PubMed ID: 16157517
Catalase plays a critical role in the CSF-independent survival of human macrophages via regulation of the expression of BCL-2 family.
Komuro I, Yasuda T, Iwamoto A, Akagawa KS
J Biol Chem. 2005
PubMed ID: 16204228
Nurse-like cells from patients with rheumatoid arthritis support the survival of osteoclast precursors via macrophage colony-stimulating factor production.
Tsuboi H, Udagawa N, Hashimoto J, Yoshikawa H, Takahashi N, Ochi T
Arthritis Rheum. 2005
PubMed ID: 16320327
M-CSF mediates TNF-induced inflammatory osteolysis.
Kitaura H, Zhou P, Kim HJ, Novack DV, Ross FP, Teitelbaum SL
J Clin Invest. 2005
PubMed ID: 16294221
A proteomics strategy for the enrichment of receptor-associated complexes.
Cross M, Nguyen T, Bogdanoska V, Reynolds E, Hamilton JA
Proteomics. 2005
PubMed ID: 16267818
Re-distribution of phospholipase C gamma 2 in macrophage precursors is mediated by the actin cytoskeleton under the control of the Src kinases.
Dearden-Badet MT, Mouchiroud G
Cell Signal. 2005
PubMed ID: 15899577
Paracrine regulation of vascular endothelial growth factor--a expression during macrophage-melanoma cell interaction: role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor.
Varney ML, Olsen KJ, Mosley RL, Singh RK
J Interferon Cytokine Res. 2005
PubMed ID: 16318581
M-CSF stimulated differentiation requires persistent MEK activity and MAPK phosphorylation independent of Grb2-Sos association and phosphatidylinositol 3-kinase activity.
Gobert Gosse S, Bourgin C, Liu WQ, Garbay C, Mouchiroud G
Cell Signal. 2005
PubMed ID: 16125055
Chromatin-remodeling factor INI1/hSNF5/BAF47 is involved in activation of the colony stimulating factor 1 promoter.
Pan X, Song Z, Zhai L, Li X, Zeng X
Mol Cells. 2005
PubMed ID: 16267391
Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury.
De Ciuceis C, Amiri F, Brassard P, Endemann DH, Touyz RM, Schiffrin EL
Arterioscler Thromb Vasc Biol. 2005
PubMed ID: 16100037
VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.
Niida S, Kondo T, Hiratsuka S, Hayashi S, Amizuka N, Noda T, Ikeda K, Shibuya M
Proc Natl Acad Sci U S A. 2005
PubMed ID: 16172397
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
The Runx1 transcription factor controls CSF-1-dependent and -independent growth and survival of macrophages.
Himes SR, Cronau S, Mulford C, Hume DA
Oncogene. 2005
PubMed ID: 16007221
The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion.
MacDonald KP, Rowe V, Bofinger HM, Thomas R, Sasmono T, Hume DA, Hill GR
J Immunol. 2005
PubMed ID: 16034075
Predictive value of serum macrophage colony-stimulating factor for development of aortic calcification in haemodialysis patients: a 6 year longitudinal study.
Kihara T, Miyata Y, Furukawa M, Noguchi M, Nishikido M, Koga S, Kanetake H
Nephrol Dial Transplant. 2005
PubMed ID: 15919699
Macrophage colony-stimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin.
Bourette RP, Thérier J, Mouchiroud G
Cell Signal. 2005
PubMed ID: 15894167
Diverse isoforms of colony-stimulating factor-1 have different effects on the development of stroma-dependent hematopoietic cells.
Friel J, Heberlein C, Geldmacher M, Ostertag W
J Cell Physiol. 2005
PubMed ID: 15744782
Macrophage colony-stimulating factor induces vascular endothelial growth factor production in skeletal muscle and promotes tumor angiogenesis.
Okazaki T, Ebihara S, Takahashi H, Asada M, Kanda A, Sasaki H
J Immunol. 2005
PubMed ID: 15944252
Expression of a novel recombinant stem cell factor/macrophage colony-stimulating factor fusion protein in baculovirus-infected insect cells.
Chen T, Zang Y, Zhu J, Lu H, Han J, Qin J
Protein Expr Purif. 2005
PubMed ID: 15866728
Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism.
Nakao K, Kubota S, Doi H, Eguchi T, Oka M, Fujisawa T, Nishida T, Takigawa M
Bone. 2005
PubMed ID: 15820145
Swapping function of two chromatin remodeling complexes.
Fan HY, Trotter KW, Archer TK, Kingston RE
Mol Cell. 2005
PubMed ID: 15780937
Increased blood myeloid dendritic cells and dendritic cell-poietins in Langerhans cell histiocytosis.
Rolland A, Guyon L, Gill M, Cai YH, Banchereau J, McClain K, Palucka AK
J Immunol. 2005
PubMed ID: 15728521
Antiangiogenic drugs synergize with a membrane macrophage colony-stimulating factor-based tumor vaccine to therapeutically treat rats with an established malignant intracranial glioma.
Jeffes EW, Zhang JG, Hoa N, Petkar A, Delgado C, Chong S, Obenaus A, Sanchez R, Khalaghizadeh S, Khomenko T, Knight BA, Alipanah R, Nguyen TV, Shah C, Vohra S, Zhuang JL, Liu J, Wepsic HT, Jadus MR
J Immunol. 2005
PubMed ID: 15728459
TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro.
Subramaniam M, Gorny G, Johnsen SA, Monroe DG, Evans GL, Fraser DG, Rickard DJ, Rasmussen K, van Deursen JM, Turner RT, Oursler MJ, Spelsberg TC
Mol Cell Biol. 2005
PubMed ID: 15657444
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury.
Pull SL, Doherty JM, Mills JC, Gordon JI, Stappenbeck TS
Proc Natl Acad Sci U S A. 2005
PubMed ID: 15615857
Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo.
Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H
J Immunol. 2004
PubMed ID: 15585886
CSF-1 regulation of the wandering macrophage: complexity in action.
Pixley FJ, Stanley ER
Trends Cell Biol. 2004
PubMed ID: 15519852
Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.
Probst-Kepper M, Hecht HJ, Herrmann H, Janke V, Ocklenburg F, Klempnauer J, van den Eynde BJ, Weiss S
J Immunol. 2004
PubMed ID: 15494511
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
Matsumoto M, Kogawa M, Wada S, Takayanagi H, Tsujimoto M, Katayama S, Hisatake K, Nogi Y
J Biol Chem. 2004
PubMed ID: 15304486
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice.
Lenda DM, Stanley ER, Kelley VR
J Immunol. 2004
PubMed ID: 15383612
TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF.
Zauli G, Rimondi E, Nicolin V, Melloni E, Celeghini C, Secchiero P
Blood. 2004
PubMed ID: 15213096
Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor.
Lagumdzija A, Bucht E, Stark A, Hulting AL, Petersson M
Regul Pept. 2004
PubMed ID: 15256272
The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiation.
Mancini A, Koch A, Whetton AD, Tamura T
Oncogene. 2004
PubMed ID: 15221008
GM-CSF cannot substitute for M-CSF in human osteoclastogenesis.
Hodge JM, Kirkland MA, Nicholson GC
Biochem Biophys Res Commun. 2004
PubMed ID: 15358207
Mouse susceptibility to anthrax lethal toxin is influenced by genetic factors in addition to those controlling macrophage sensitivity.
Moayeri M, Martinez NW, Wiggins J, Young HA, Leppla SH
Infect Immun. 2004
PubMed ID: 15271901
Macrophage colony-stimulating factor-, granulocyte-macrophage colony-stimulating factor-, or IL-3-dependent survival of macrophages, but not proliferation, requires the expression of p21(Waf1) through the phosphatidylinositol 3-kinase/Akt pathway.
Comalada M, Xaus J, Sánchez E, Valledor AF, Celada A
Eur J Immunol. 2004
PubMed ID: 15259023
Roles of stromal cell RANKL, OPG, and M-CSF expression in biphasic TGF-beta regulation of osteoclast differentiation.
Karst M, Gorny G, Galvin RJ, Oursler MJ
J Cell Physiol. 2004
PubMed ID: 15137062
Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation.
Kirma N, Luthra R, Jones J, Liu YG, Nair HB, Mandava U, Tekmal RR
Cancer Res. 2004
PubMed ID: 15205327
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy.
Wautier MP, Boulanger E, Guillausseau PJ, Massin P, Wautier JL
Thromb Haemost. 2004
PubMed ID: 15116247
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Estrogen regulates the production of VEGF for osteoclast formation and activity in op/op mice.
Kodama I, Niida S, Sanada M, Yoshiko Y, Tsuda M, Maeda N, Ohama K
J Bone Miner Res. 2004
PubMed ID: 14969389
Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.
Jenkins BJ, Grail D, Inglese M, Quilici C, Bozinovski S, Wong P, Ernst M
Mol Cell Biol. 2004
PubMed ID: 14749363
Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML.
Zheng R, Klang K, Gorin NC, Small D
Leuk Res. 2004
PubMed ID: 14654075
Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1.
Dai XM, Zong XH, Sylvestre V, Stanley ER
Blood. 2004
PubMed ID: 14525772
Significant correlation of matrix metalloproteinase and macrophage colony-stimulating factor serum concentrations in patients with head and neck cancer.
Kuropkat C, Duenne AA, Herz U, Renz H, Werner JA
Neoplasma. 2004
PubMed ID: 15640942
A mechanism of transcriptional regulation of the CSF-1 gene by interferon-gamma.
Tsuchimoto D, Tojo A, Asano S
Immunol Invest. 2004
PubMed ID: 15624698
Hematopoietic cytokines as tumor markers.
Mroczko B, Szmitkowski M
Clin Chem Lab Med. 2004
PubMed ID: 15576295
Unpolymerized nuclear actin is involved in the activation of CSF-1 gene transcription.
Song Z, Zeng X, Wang M, Liu W, Huang B, Hao S
Cell Biol Int. 2004
PubMed ID: 15261158
A new histomorphometric method to assess growth plate chondrodysplasia and its application to the toothless (tl, Csf1(null)) osteopetrotic rat.
Devraj K, Bonassar LJ, MacKay CA, Mason-Savas A, Gartland A, Odgren PR
Connect Tissue Res. 2004
PubMed ID: 15203935
Macrophages: modulators of breast cancer progression.
Lin EY, Pollard JW
Novartis Found Symp. 2004
PubMed ID: 15027489
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Elevation of serum macrophage colony-stimulating factor before the clinical manifestations of preeclampsia.
Hayashi M, Ohkura T, Inaba N
Am J Obstet Gynecol. 2003
PubMed ID: 14634568
Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1.
Jones GE, Prigmore E, Calvez R, Hogan C, Dunn GA, Hirsch E, Wymann MP, Ridley AJ
Exp Cell Res. 2003
PubMed ID: 14516793
Amyloid beta protein deposition and neuron loss in osteopetrotic (op/op) mice.
Kaku M, Tsutsui K, Motokawa M, Kawata T, Fujita T, Kohno S, Tohma Y, Ohtani J, Tenjoh K, Tanne K
Brain Res Brain Res Protoc. 2003
PubMed ID: 14613812
Increased levels of serum macrophage colony-stimulating factor before the onset of preeclampsia.
Hayashi M, Ohkura T, Inaba N
Horm Metab Res. 2003
PubMed ID: 14605992
Macrophage colony-stimulating factor as a tumor marker for squamous cell carcinoma of the head and neck.
Kuropkat C, Dünne AA, Plehn S, Ossendorf M, Herz U, Renz H, Werner JA
Tumour Biol. 2003
PubMed ID: 15001836
M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes.
Eubank TD, Galloway M, Montague CM, Waldman WJ, Marsh CB
J Immunol. 2003
PubMed ID: 12928417
Osteoblast-specific targeting of soluble colony-stimulating factor-1 increases cortical bone thickness in mice.
Abboud SL, Ghosh-Choudhury N, Liu LC, Shen V, Woodruff K
J Bone Miner Res. 2003
PubMed ID: 12929928
Serum concentrations of vascular endothelial growth factor and monocyte-colony stimulating factor in peripheral arterial disease.
Matsui K, Yoshioka T, Murakami Y, Takahashi M, Shimada K, Ikeda U
Circ J. 2003
PubMed ID: 12890905
The cell surface form of colony-stimulating factor-1 is biologically active in bone in vivo.
Yao GQ, Wu JJ, Sun BH, Troiano N, Mitnick MA, Insogna K
Endocrinology. 2003
PubMed ID: 12865350
Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone.
Karlsson MC, Guinamard R, Bolland S, Sankala M, Steinman RM, Ravetch JV
J Exp Med. 2003
PubMed ID: 12874264
Serum levels of macrophage colony-stimulating factor after cesarean section, vaginal delivery, or laparotomy in normal pregnant women and gynecologic patients.
Hayashi M, Shibazaki M, Sohma R, Ohkura T, Inaba N
Acta Obstet Gynecol Scand. 2003
PubMed ID: 12790839
PDGF BB and bFGF stimulate DNA synthesis and upregulate CSF-1 and MCP-1 gene expression in dental follicle cells.
Bsoul S, Terezhalmy G, Abboud H, Woodruff K, Abboud SL
Arch Oral Biol. 2003
PubMed ID: 12749918
Monocyte and macrophage functions in M-CSF-deficient op/op mice during experimental leishmaniasis.
Schönlau F, Schlesiger C, Ehrchen J, Grabbe S, Sorg C, Sunderkötter C, Ehrehen J
J Leukoc Biol. 2003
PubMed ID: 12714570
Xenogeneic skin graft rejection in M-CSF/macrophage deficient osteopetrotic mice.
Zhao Y, Xiong W, Yang T, Prall A, Baxter BT, Langnas AN
Xenotransplantation. 2003
PubMed ID: 12694543
Regulation of the cellular subpopulation ratios of normal human endometrial stromal cells by macrophage colony-stimulating factor.
Tanaka T, Umesaki N
Int J Mol Med. 2003
PubMed ID: 12684699
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease.
Bruhns P, Samuelsson A, Pollard JW, Ravetch JV
Immunity. 2003
PubMed ID: 12705859
Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation.
Lenda DM, Kikawada E, Stanley ER, Kelley VR
J Immunol. 2003
PubMed ID: 12626584
Blockade of macrophage colony-stimulating factor reduces macrophage proliferation and accumulation in renal allograft rejection.
Jose MD, Le Meur Y, Atkins RC, Chadban SJ
Am J Transplant. 2003
PubMed ID: 12614284
Indoleamine 2,3-dioxygenase is regulated by IFN-gamma in the mouse placenta during Listeria monocytogenes infection.
Mackler AM, Barber EM, Takikawa O, Pollard JW
J Immunol. 2003
PubMed ID: 12517946
The effects of colony-stimulating factor-1 (CSF-1) on the development of osteoclasts and their expression of tartrate-resistant acid phosphatase (TRAP) in toothless (tl-osteopetrotic) rats.
Norgård M, Marks SC, Reinholt FP, Andersson G
Crit Rev Eukaryot Gene Expr. 2003
PubMed ID: 14696961
CSF-1 as a regulator of macrophage activation and immune responses.
Sweet MJ, Hume DA
Arch Immunol Ther Exp (Warsz). 2003
PubMed ID: 12894871
Effects of colony-stimulating factors on the secretion of platelet-activating factor acetylhydrolase by human decidual macrophages.
Narahara H, Mine S, Kawano Y, Johnston JM, Miyakawa I
Am J Obstet Gynecol. 2003
PubMed ID: 12548211
Interferon-gamma switches monocyte differentiation from dendritic cells to macrophages.
Delneste Y, Charbonnier P, Herbault N, Magistrelli G, Caron G, Bonnefoy JY, Jeannin P
Blood. 2003
PubMed ID: 12393446
Conformational analysis of intermediates involved in the in vitro folding pathways of recombinant human macrophage colony stimulating factor beta by sulfhydryl group trapping and hydrogen/deuterium pulsed labeling.
Zhang YH, Yan X, Maier CS, Schimerlik MI, Deinzer ML
Biochemistry. 2002
PubMed ID: 12501178
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification.
Van Wesenbeeck L, Odgren PR, MacKay CA, D'Angelo M, Safadi FF, Popoff SN, Van Hul W, Marks SC
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12379742
Vitamin D(3) and analogues modulate the expression of CSF-1 and its receptor in human dendritic cells.
Zhu K, Gläser R, Mrowietz U
Biochem Biophys Res Commun. 2002
PubMed ID: 12372416
Macrophage accumulation at a site of renal inflammation is dependent on the M-CSF/c-fms pathway.
Le Meur Y, Tesch GH, Hill PA, Mu W, Foti R, Nikolic-Paterson DJ, Atkins RC
J Leukoc Biol. 2002
PubMed ID: 12223521
Characteristics of mastication in the anodontic mouse.
Kobayashi M, Masuda Y, Kishino M, Ishida T, Maeda N, Morimoto T
J Dent Res. 2002
PubMed ID: 12202638
Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation.
Re F, Belyanskaya SL, Riese RJ, Cipriani B, Fischer FR, Granucci F, Ricciardi-Castagnoli P, Brosnan C, Stern LJ, Strominger JL, Santambrogio L
J Immunol. 2002
PubMed ID: 12193691
[Expression of macrophage colony-stimulating factor in human luteinized granulosa cells]
Zhang Z, Salmassi A, Mettler L
Zhonghua Fu Chan Ke Za Zhi. 2002
PubMed ID: 12411027
Colony-stimulating factor 1-dependent cells protect against systemic infection with Listeria monocytogenes but facilitate neuroinvasion.
Jin Y, Dons L, Kristensson K, Rottenberg ME
Infect Immun. 2002
PubMed ID: 12117983
HGF and M-CSF modulate adhesion of MDA-231 breast cancer cell by increasing osteopontin secretion.
Grano M, Mori G, Minielli V, Colucci S, Vaira S, Giannelli G, Martemucci S, Giorgino F, Zallone AZ
J Biol Regul Homeost Agents. 2002
PubMed ID: 12456016
Disturbed tooth eruption in osteopetrotic (op/op) mice: histopathogenesis of tooth malformation and odontomas.
Ida-Yonemochi H, Noda T, Shimokawa H, Saku T
J Oral Pathol Med. 2002
PubMed ID: 12201247
Colony stimulating factor-1 is required to recruit macrophages into the mammary gland to facilitate mammary ductal outgrowth.
Van Nguyen A, Pollard JW
Dev Biol. 2002
PubMed ID: 12074549
Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat.
Dobbins DE, Sood R, Hashiramoto A, Hansen CT, Wilder RL, Remmers EF
Biochem Biophys Res Commun. 2002
PubMed ID: 12074592
Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B.
Cappellen D, Luong-Nguyen NH, Bongiovanni S, Grenet O, Wanke C, Susa M
J Biol Chem. 2002
PubMed ID: 11923298
Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice.
Deckers MM, Van Beek ER, Van Der Pluijm G, Wetterwald A, Van Der Wee-Pals L, Cecchini MG, Papapoulos SE, Löwik CW
J Bone Miner Res. 2002
PubMed ID: 12054176
Expression of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor in normal and inflamed rat testis.
Gerdprasert O, O'Bryan MK, Nikolic-Paterson DJ, Sebire K, de Kretser DM, Hedger MP
Mol Hum Reprod. 2002
PubMed ID: 12029068
Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages.
Rovida E, Baccarini M, Olivotto M, Dello Sbarba P
Oncogene. 2002
PubMed ID: 12032835
Rescue of the osteopetrotic defect in op/op mice by osteoblast-specific targeting of soluble colony-stimulating factor-1.
Abboud SL, Woodruff K, Liu C, Shen V, Ghosh-Choudhury N
Endocrinology. 2002
PubMed ID: 11956177
A role for cell-surface CSF-1 in osteoblast-mediated osteoclastogenesis.
Yao GQ, Sun BH, Weir EC, Insogna KL
Calcif Tissue Int. 2002
PubMed ID: 12004339
Colony-stimulating factor 1 regulation of neuroendocrine pathways that control gonadal function in mice.
Cohen PE, Zhu L, Nishimura K, Pollard JW
Endocrinology. 2002
PubMed ID: 11897698
Periwound dopaminergic sprouting is dependent on numbers of wound macrophages.
Batchelor PE, Porritt MJ, Nilsson SK, Bertoncello I, Donnan GA, Howells DW
Eur J Neurosci. 2002
PubMed ID: 11906524
Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.
Shima Y, Copeland NG, Gilbert DJ, Jenkins NA, Chisaka O, Takeichi M, Uemura T
Dev Dyn. 2002
PubMed ID: 11891983
Fluctuations in plasma macrophage colony-stimulating factor levels during autologous peripheral blood stem cell transplantation for haematologic diseases.
Saigo K, Sugimoto T, Matsui T, Ryo R, Kumagai S
Clin Lab Haematol. 2002
PubMed ID: 11843897
Metallothionein is required for zinc-induced expression of the macrophage colony stimulating factor gene.
Kanekiyo M, Itoh N, Kawasaki A, Matsuda K, Nakanishi T, Tanaka K
J Cell Biochem. 2002
PubMed ID: 12112025
Macrophage colony-stimulating factor and receptor activator NF-kappaB ligand fail to rescue osteoclast-poor human malignant infantile osteopetrosis in vitro.
Flanagan AM, Massey HM, Wilson C, Vellodi A, Horton MA, Steward CG
Bone. 2002
PubMed ID: 11792569
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects.
Dai XM, Ryan GR, Hapel AJ, Dominguez MG, Russell RG, Kapp S, Sylvestre V, Stanley ER
Blood. 2002
PubMed ID: 11756160
Gab3, a new DOS/Gab family member, facilitates macrophage differentiation.
Wolf I, Jenkins BJ, Liu Y, Seiffert M, Custodio JM, Young P, Rohrschneider LR
Mol Cell Biol. 2002
PubMed ID: 11739737
Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema.
Shibata Y, Zsengeller Z, Otake K, Palaniyar N, Trapnell BC
Blood. 2001
PubMed ID: 11675359
Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle.
Mueller CG, Cremer I, Paulet PE, Niida S, Maeda N, Lebeque S, Fridman WH, Sautès-Fridman C
J Immunol. 2001
PubMed ID: 11673514
Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice.
Weilbaecher KN, Motyckova G, Huber WE, Takemoto CM, Hemesath TJ, Xu Y, Hershey CL, Dowland NR, Wells AG, Fisher DE
Mol Cell. 2001
PubMed ID: 11684011
Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response.
Mitrasinovic OM, Perez GV, Zhao F, Lee YL, Poon C, Murphy GM
J Biol Chem. 2001
PubMed ID: 11387343
Microglia and the early phase of immune surveillance in the axotomized facial motor nucleus: impaired microglial activation and lymphocyte recruitment but no effect on neuronal survival or axonal regeneration in macrophage-colony stimulating factor-defici
Kalla R, Liu Z, Xu S, Koppius A, Imai Y, Kloss CU, Kohsaka S, Gschwendtner A, Möller JC, Werner A, Raivich G
J Comp Neurol. 2001
PubMed ID: 11438923
Genetic loci influencing natural variations in femoral bone morphometry in mice.
Drake TA, Hannani K, Kabo JM, Villa V, Krass K, Lusis AJ
J Orthop Res. 2001
PubMed ID: 11518254
Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis.
Ryan GR, Dai XM, Dominguez MG, Tong W, Chuan F, Chisholm O, Russell RG, Pollard JW, Stanley ER
Blood. 2001
PubMed ID: 11418465
Neural change in Trichinella-infected mice is MHC II independent and involves M-CSF-derived macrophages.
Galeazzi F, Lovato P, Blennerhassett PA, Haapala EM, Vallance BA, Collins SM
Am J Physiol Gastrointest Liver Physiol. 2001
PubMed ID: 11408267
Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal.
Bourette RP, De Sepulveda P, Arnaud S, Dubreuil P, Rottapel R, Mouchiroud G
J Biol Chem. 2001
PubMed ID: 11297560
An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes.
Probst-Kepper M, Stroobant V, Kridel R, Gaugler B, Landry C, Brasseur F, Cosyns JP, Weynand B, Boon T, Van Den Eynde BJ
J Exp Med. 2001
PubMed ID: 11369790
Regulation of cell survival during B lymphopoiesis in mouse bone marrow: enhanced pre-B-cell apoptosis in CSF-1-deficient op/op mutant mice.
Lu L, Osmond DG
Exp Hematol. 2001
PubMed ID: 11376872
Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells.
Hemmi H, Yoshino M, Yamazaki H, Naito M, Iyoda T, Omatsu Y, Shimoyama S, Letterio JJ, Nakabayashi T, Tagaya H, Yamane T, Ogawa M, Nishikawa S, Ryoke K, Inaba K, Hayashi S, Kunisada T
Int Immunol. 2001
PubMed ID: 11312257
Analysis of histochemically and morphometrically in the anterior belly digastric muscle of osteopetrotic (op/op) mice.
Kawata T, Fujita T, Tokimasa C, Sugiyama H, Ozawa S, Tanne K
Exp Anim. 2001
PubMed ID: 11381616
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy.
Lin EY, Nguyen AV, Russell RG, Pollard JW
J Exp Med. 2001
PubMed ID: 11257139
The effect of macrophage-colony stimulating factor and other humoral factors (interleukin-1, -3, -6, and -11, tumor necrosis factor-alpha, and granulocyte macrophage-colony stimulating factor) on human osteoclast formation from circulating cells.
Fujikawa Y, Sabokbar A, Neale SD, Itonaga I, Torisu T, Athanasou NA
Bone. 2001
PubMed ID: 11248655
Aberrant macrophage and neutrophil population dynamics and impaired Th1 response to Listeria monocytogenes in colony-stimulating factor 1-deficient mice.
Guleria I, Pollard JW
Infect Immun. 2001
PubMed ID: 11179357
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0.
Carenini S, Mäurer M, Werner A, Blazyca H, Toyka KV, Schmid CD, Raivich G, Martini R
J Cell Biol. 2001
PubMed ID: 11266447
Histochemical examination of osteoblastic activity in op/op mice with or without injection of recombinant M-CSF.
Nishino I, Amizuka N, Ozawa H
J Bone Miner Metab. 2001
PubMed ID: 11498728
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Nuclear factor-kappaB p50 is required for tumor necrosis factor-alpha-induced colony-stimulating factor-1 gene expression in osteoblasts.
Yao GQ, Sun BH, Insogna KL, Weir EC
Endocrinology. 2000
PubMed ID: 10919279
The colony-stimulating factors and collagen-induced arthritis: exacerbation of disease by M-CSF and G-CSF and requirement for endogenous M-CSF.
Campbell IK, Rich MJ, Bischof RJ, Hamilton JA
J Leukoc Biol. 2000
PubMed ID: 10914502
Effects of macrophage-colony-stimulating factor deficiency on the maturation of microglia and brain macrophages and on their expression of scavenger receptor.
Sasaki A, Yokoo H, Naito M, Kaizu C, Shultz LD, Nakazato Y
Neuropathology. 2000
PubMed ID: 10935450
Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
Tagaya H, Kunisada T, Yamazaki H, Yamane T, Tokuhisa T, Wagner EF, Sudo T, Shultz LD, Hayashi SI
Blood. 2000
PubMed ID: 10828017
Postnatal mammary gland development requires macrophages and eosinophils.
Gouon-Evans V, Rothenberg ME, Pollard JW
Development. 2000
PubMed ID: 10804170
Effect of cytokines and growth factors on the macrophage colony-stimulating factor secretion by human bone marrow stromal cells.
Besse A, Trimoreau F, Praloran V, Denizot Y
Cytokine. 2000
PubMed ID: 10857771
The trophoblast is a component of the innate immune system during pregnancy.
Guleria I, Pollard JW
Nat Med. 2000
PubMed ID: 10802718
Tumor necrosis factor and the p55TNF receptor are required for optimal development of the marginal sinus and for migration of follicular dendritic cell precursors into splenic follicles.
Pasparakis M, Kousteni S, Peschon J, Kollias G
Cell Immunol. 2000
PubMed ID: 10805971
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages.
Scheuerer B, Ernst M, Dürrbaum-Landmann I, Fleischer J, Grage-Griebenow E, Brandt E, Flad HD, Petersen F
Blood. 2000
PubMed ID: 10666185
Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation.
Kieslinger M, Woldman I, Moriggl R, Hofmann J, Marine JC, Ihle JN, Beug H, Decker T
Genes Dev. 2000
PubMed ID: 10652277
Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo.
Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA
Immunity. 1999
PubMed ID: 10626897
Facial skeletal growth in growing "toothless" osteopetrotic (op/op) mice: radiographic findings.
Kawata T, Tokimasa C, Fujita T, Ozawa S, Sugiyama H, Tanne K
J Craniofac Genet Dev Biol. 1999
PubMed ID: 10731091
Experimental liver injury induced by Propionibacterium acnes and lipopolysaccharide in macrophage colony stimulating factor-deficient osteopetrotic (op/op) mice.
Nishioji K, Okanoue T, Mori T, Sakamoto S, Itoh Y
Dig Dis Sci. 1999
PubMed ID: 10548345
A characterization of vitamin D-independent intestinal calcium absorption in the osteopetrotic (op/op) mouse.
McCary LC, Staun M, DeLuca HF
Arch Biochem Biophys. 1999
PubMed ID: 10441375
Mechanism in inhibitory effects of vitamin K2 on osteoclastic bone resorption: in vivo study in osteopetrotic (op/op) mice.
Kawata T, Zernik JH, Fujita T, Tokimasa C, Tanne K
J Nutr Sci Vitaminol (Tokyo). 1999
PubMed ID: 10575640
Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density.
Umeda S, Beamer WG, Takagi K, Naito M, Hayashi S, Yonemitsu H, Yi T, Shultz LD
Am J Pathol. 1999
PubMed ID: 10393854
Dental abnormalities associated with failure of tooth eruption in src knockout and op/op mice.
Tiffee JC, Xing L, Nilsson S, Boyce BF
Calcif Tissue Int. 1999
PubMed ID: 10369734
Lack of the bone remodeling in osteopetrotic (op/op) mice associated with microdontia.
Kawata T, Tokimasa C, Nowroozi N, Fujita T, Kaku M, Kawasoko S, Sugiyama H, Ozawa S, Zernik JH, Tanne K
J Craniofac Genet Dev Biol. 1999
PubMed ID: 10416155
Remodeling of the sagittal suture in osteopetrotic (op/op) mice associated with cranial flat bone growth.
Kaku M, Kawata T, Kawasoko S, Fujita T, Tokimasa C, Tanne K
J Craniofac Genet Dev Biol. 1999
PubMed ID: 10416154
Op/op mice defective in production of functional colony-stimulating factor-1 lack macrophages in muscularis externa of the small intestine.
Mikkelsen HB, Thuneberg L
Cell Tissue Res. 1999
PubMed ID: 10022968
Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.
Myint YY, Miyakawa K, Naito M, Shultz LD, Oike Y, Yamamura K, Takahashi K
Am J Pathol. 1999
PubMed ID: 10027413
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen.
Ngo VN, Korner H, Gunn MD, Schmidt KN, Riminton DS, Cooper MD, Browning JL, Sedgwick JD, Cyster JG
J Exp Med. 1999
PubMed ID: 9892622
The role of CSF-1 in normal and neoplastic breast physiology.
Sapi E, Kacinski BM
Proc Soc Exp Biol Med. 1999
PubMed ID: 9893162
Morphological change of the nasopremaxillary suture in growing "toothless" osteopetrotic (op/op) mice.
Kawata T, Tokimasa C, Fujita T, Kaku M, Kawasoko S, Sugiyama H, Ozawa S, Tanne K
J Craniofac Genet Dev Biol. 1999
PubMed ID: 10378148
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Recruitment of osteoclasts in the mandibular condyle of growing osteopetrotic (op/op) mice after a single injection of macrophage colony-stimulating factor.
Kawata T, Kawasoko S, Kaku M, Fujita T, Tokimasa C, Niida S, Tanne K
Arch Oral Biol. 1999
PubMed ID: 10075153
Expression pattern and neurotrophic role of the c-fms proto-oncogene M-CSF receptor in rodent Purkinje cells.
Murase S, Hayashi Y
J Neurosci. 1998
PubMed ID: 9852586
Expression of macrophage colony-stimulating factor, scavenger receptors, and macrophage proliferation in the pregnant mouse uterus.
Kyaw Y, Hasegawa G, Takatsuka H, Shimada-Hiratsuka M, Umezu H, Arakawa M, Naito M
Arch Histol Cytol. 1998
PubMed ID: 9990422
Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes.
Jin HM, Copeland NG, Gilbert DJ, Jenkins NA, Kirkpatrick RB, Rosenberg M
Genomics. 1998
PubMed ID: 9828134
Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF).
Gao YH, Shinki T, Yuasa T, Kataoka-Enomoto H, Komori T, Suda T, Yamaguchi A
Biochem Biophys Res Commun. 1998
PubMed ID: 9837769
Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.
Srivastava S, Weitzmann MN, Kimble RB, Rizzo M, Zahner M, Milbrandt J, Ross FP, Pacifici R
J Clin Invest. 1998
PubMed ID: 9819371
AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.
Okada H, Watanabe T, Niki M, Takano H, Chiba N, Yanai N, Tani K, Hibino H, Asano S, Mucenski ML, Ito Y, Noda T, Satake M
Oncogene. 1998
PubMed ID: 9811459
Midpalatal suture of osteopetrotic (op/op) mice exhibits immature fusion.
Kawata T, Tokimasa C, Fujita T, Kawasoko S, Kaku M, Sugiyama H, Tanne K
Exp Anim. 1998
PubMed ID: 10067173
Reduced number and altered morphology of microglial cells in colony stimulating factor-1-deficient osteopetrotic op/op mice.
Wegiel J, Wiśniewski HM, Dziewiatkowski J, Tarnawski M, Kozielski R, Trenkner E, Wiktor-Jedrzejczak W
Brain Res. 1998
PubMed ID: 9729335
Human monocyte-derived macrophages secrete two forms of proteoglycan-macrophage colony-stimulating factor that differ in their ability to bind low density lipoproteins.
Chang MY, Olin KL, Tsoi C, Wight TN, Chait A
J Biol Chem. 1998
PubMed ID: 9632647
Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice.
Rajavashisth T, Qiao JH, Tripathi S, Tripathi J, Mishra N, Hua M, Wang XP, Loussararian A, Clinton S, Libby P, Lusis A
J Clin Invest. 1998
PubMed ID: 9637704
The effects of colony-stimulating factor-1 on the distribution of mononuclear phagocytes in the developing osteopetrotic mouse.
Roth P, Dominguez MG, Stanley ER
Blood. 1998
PubMed ID: 9573014
Identification of alternatively spliced transcripts encoding murine macrophage colony-stimulating factor.
Suzu S, Hatake K, Ota J, Mishima Y, Yamada M, Shimamura S, Kimura F, Motoyoshi K
Biochem Biophys Res Commun. 1998
PubMed ID: 9535794
Bone remodeling and macrophage differentiation in osteopetrosis (op) mutant mice defective in the production of macrophage colony-stimulating factor.
Takatsuka H, Umezu H, Hasegawa G, Usuda H, Ebe Y, Naito M, Shultz LD
J Submicrosc Cytol Pathol. 1998
PubMed ID: 9648288
Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E.
de Villiers WJ, Smith JD, Miyata M, Dansky HM, Darley E, Gordon S
Arterioscler Thromb Vasc Biol. 1998
PubMed ID: 9555870
Aberrant regulation of bone trace elements in motheaten and osteopetrosis mutant mice.
Yamada G, Nakamura S, Haraguchi R, Sakai M, Suzuki K, Miyado K, Hasuwa H, Ogino Y, Minami T, Tohno Y, Blum M, Shultz LD
Cell Mol Biol (Noisy-le-grand). 1998
PubMed ID: 9593582
The cell-surface form of colony-stimulating factor-1 is regulated by osteotropic agents and supports formation of multinucleated osteoclast-like cells.
Yao GQ, Sun B, Hammond EE, Spencer EN, Horowitz MC, Insogna KL, Weir EC
J Biol Chem. 1998
PubMed ID: 9461606
Effect of macrophage colony-stimulating factor (M-CSF) on mouse immune responses in vivo.
Sakurai T, Wakimoto N, Yamada M, Shimamura S, Motoyoshi K
Immunopharmacol Immunotoxicol. 1998
PubMed ID: 9543701
Normal development of dental innervation and nerve/tissue interactions in the colony-stimulating factor-1 deficient osteopetrotic mouse.
Nagahama SI, Cunningham ML, Lee MY, Byers MR
Dev Dyn. 1998
PubMed ID: 9438423
Heterogeneity among cells that express osteoclast-associated genes in developing bone.
Jemtland R, Lee K, Segre GV
Endocrinology. 1998
PubMed ID: 9421432
Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.
Davis JN, Rock CO, Cheng M, Watson JB, Ashmun RA, Kirk H, Kay RJ, Roussel MF
Mol Cell Biol. 1997
PubMed ID: 9372970
Hypophosphatemia and the development of rickets in osteopetrotic (op/op) mice.
McCary LC, Smith CM, DeLuca HF
J Bone Miner Res. 1997
PubMed ID: 9383699
The effects of colony-stimulating factor-1 on the number and ultrastructure of osteoclasts in toothless (tl) rats and osteopetrotic (op) mice.
Marks SC, Iizuka T, MacKay CA, Mason-Savas A, Cielinski MJ
Tissue Cell. 1997
PubMed ID: 9364807
Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice.
Cohen PE, Hardy MP, Pollard JW
Mol Endocrinol. 1997
PubMed ID: 9328346
Priming of mouse macrophages with the macrophage colony-stimulating factor (CSF-1) induces a variety of pathways that regulate expression of the interleukin 6 (Il6) and granulocyte-macrophage colony-stimulating factor (Csfgm) genes.
Kamdar SJ, Fuller JA, Nishikawa SI, Evans R
Exp Cell Res. 1997
PubMed ID: 9281358
CSF-1 signal transduction.
Hamilton JA
J Leukoc Biol. 1997
PubMed ID: 9261328
Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice.
Lagasse E, Weissman IL
Cell. 1997
PubMed ID: 9215625
Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells.
Ashihara E, Vannucchi AM, Migliaccio G, Migliaccio AR
J Cell Physiol. 1997
PubMed ID: 9180904
Expression of macrophage colony-stimulating factor and its receptor in hepatic granulomas of Kupffer-cell-depleted mice.
Moriyama H, Yamamoto T, Takatsuka H, Umezu H, Tokunaga K, Nagano T, Arakawa M, Naito M
Am J Pathol. 1997
PubMed ID: 9176397
CSF-1-induced and constitutive Il6 gene expression in mouse macrophages: evidence for PKC-dependent and -independent pathways.
Kamdar SJ, Fuller JA, Evans R
Exp Cell Res. 1997
PubMed ID: 9168824
Effect of the colony-stimulating factor-1 null mutation, osteopetrotic (csfm(op)), on the distribution of macrophages in the male mouse reproductive tract.
Pollard JW, Dominguez MG, Mocci S, Cohen PE, Stanley ER
Biol Reprod. 1997
PubMed ID: 9160730
Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.
Qiao JH, Tripathi J, Mishra NK, Cai Y, Tripathi S, Wang XP, Imes S, Fishbein MC, Clinton SK, Libby P, Lusis AJ, Rajavashisth TB
Am J Pathol. 1997
PubMed ID: 9137093
The promoter of macrophage colony-stimulating factor receptor is active in astrocytes.
Tkachuk M, Gisler RH
Neurosci Lett. 1997
PubMed ID: 9147389
Restoration of disturbed tooth eruption in osteopetrotic (op/op) mice by injection of macrophage colony-stimulating factor.
Niida S, Abe M, Suemune S, Yoshiko Y, Maeda N, Yamasaki A
Exp Anim. 1997
PubMed ID: 9145288
Colony-forming cells expressing high levels of CD34 are the main targets for granulocyte colony-stimulating factor and macrophage colony-stimulating factor in the human fetal liver.
Muench MO, Roncarolo MG, Rosnet O, Birnbaum D, Namikawa R
Exp Hematol. 1997
PubMed ID: 9131001
Increased circulating colony-stimulating factor-1 (CSF-1) in SJL/J mice with radiation-induced acute myeloid leukemia (AML) is associated with autocrine regulation of AML cells by CSF-1.
Haran-Ghera N, Krautghamer R, Lapidot T, Peled A, Dominguez MG, Stanley ER
Blood. 1997
PubMed ID: 9116300
Osteoclast formation during tumor osteolysis does not require proliferating osteoclast precursor cells.
Clohisy DR, Ramnaraine ML
J Orthop Res. 1997
PubMed ID: 9167635
Absence of colony stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice disrupts estrous cycles and ovulation.
Cohen PE, Zhu L, Pollard JW
Biol Reprod. 1997
PubMed ID: 9002639
Macrophage differentiation and granulomatous inflammation in osteopetrotic mice (op/op) defective in the production of CSF-1.
Naito M, Umeda S, Takahashi K, Shultz LD
Mol Reprod Dev. 1997
PubMed ID: 8981368
Relative role of CSF-1, MCP-1/JE, and RANTES in macrophage recruitment during successful pregnancy.
Wood GW, Hausmann E, Choudhuri R
Mol Reprod Dev. 1997
PubMed ID: 8981365
Role of colony-stimulating factor-1 in reproduction and development.
Pollard JW
Mol Reprod Dev. 1997
PubMed ID: 8981364
Transcriptional regulation of the mouse CSF-1 gene.
Harrington M, Konicek BW, Xia XL, Song A
Mol Reprod Dev. 1997
PubMed ID: 8981362
CSF-1 and cell cycle control in macrophages.
Hamilton JA
Mol Reprod Dev. 1997
PubMed ID: 8981359
Biology and action of colony--stimulating factor-1.
Stanley ER, Berg KL, Einstein DB, Lee PS, Pixley FJ, Wang Y, Yeung YG
Mol Reprod Dev. 1997
PubMed ID: 8981357
Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand.
McClanahan T, Culpepper J, Campbell D, Wagner J, Franz-Bacon K, Mattson J, Tsai S, Luh J, Guimaraes MJ, Mattei MG, Rosnet O, Birnbaum D, Hannum CH
Blood. 1996
PubMed ID: 8896402
Cytokine regulation of the macrophage (M phi) system studied using the colony stimulating factor-1-deficient op/op mouse.
Wiktor-Jedrzejczak W, Gordon S
Physiol Rev. 1996
PubMed ID: 8874489
Myoblast-mediated expression of colony stimulating factor-1 (CSF-1) in the cytokine-deficient op/op mouse.
Dhawan J, Rando TA, Elson SE, Lee F, Stanley ER, Blau HM
Somat Cell Mol Genet. 1996
PubMed ID: 9039846
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Glomerular expression of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in patients with various forms of glomerulonephritis.
Matsuda M, Shikata K, Makino H, Sugimoto H, Ota Z
Lab Invest. 1996
PubMed ID: 8804363
CSF-1 deficiency in mice results in abnormal brain development.
Michaelson MD, Bieri PL, Mehler MF, Xu H, Arezzo JC, Pollard JW, Kessler JA
Development. 1996
PubMed ID: 8787741
Activation of mesangial cells with TNF-alpha stimulates M-CSF gene expression and monocyte proliferation: evidence for involvement of protein kinase C and protein tyrosine kinase.
Kamanna VS, Pai R, Bassa B, Kirschenbaum MA
Biochim Biophys Acta. 1996
PubMed ID: 8781564
Absence of colony-stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects.
Cohen PE, Chisholm O, Arceci RJ, Stanley ER, Pollard JW
Biol Reprod. 1996
PubMed ID: 8828834
Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor.
Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN
Mol Cell Biol. 1996
PubMed ID: 8754800
Tumor necrosis factor-alpha induces transcription of the colony-stimulating factor-1 gene in murine osteoblasts.
Kaplan DL, Eielson CM, Horowitz MC, Insogna KL, Weir EC
J Cell Physiol. 1996
PubMed ID: 8647916
Colony stimulating factor-1 expression is developmentally regulated in the mouse.
Roth P, Stanley ER
J Leukoc Biol. 1996
PubMed ID: 8691066
A defect in beta-galactosidase of B lymphocytes in the osteopetrotic (op/op) mouse.
Yamamoto N, Naraparaju VR
Immunol Lett. 1996
PubMed ID: 8793557
Osteopetrotic (op/op) mice are unable to maintain serum calcium levels despite hyperabsorption of calcium.
McCary LC, DeLuca HF
Endocrinology. 1996
PubMed ID: 8603573
Bone morphogenetic protein-induced heterotopic bone in osteopetrosis.
Miyazawa K, Kawai T, Urist MR
Clin Orthop Relat Res. 1996
PubMed ID: 8595766
Follicular development and ovulation in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Araki M, Fukumatsu Y, Katabuchi H, Shultz LD, Takahashi K, Okamura H
Biol Reprod. 1996
PubMed ID: 8788202
Recent developments in the understanding of the pathophysiology of osteopetrosis.
Felix R, Hofstetter W, Cecchini MG
Eur J Endocrinol. 1996
PubMed ID: 8630510
Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficient op/op mouse: evidence for a role of CSF-1-dependent macrophages in formation of tumor stroma.
Nowicki A, Szenajch J, Ostrowska G, Wojtowicz A, Wojtowicz K, Kruszewski AA, Maruszynski M, Aukerman SL, Wiktor-Jedrzejczak W
Int J Cancer. 1996
PubMed ID: 8543387
Neonatal changes of osteoclasts in osteopetrosis (op/op) mice defective in production of functional macrophage colony-stimulating factor (M-CSF) protein and effects of M-CSF on osteoclast development and differentiation.
Umeda S, Takahashi K, Naito M, Shultz LD, Takagi K
J Submicrosc Cytol Pathol. 1996
PubMed ID: 8929623
Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts.
Novak U, Harpur AG, Paradiso L, Kanagasundaram V, Jaworowski A, Wilks AF, Hamilton JA
Blood. 1995
PubMed ID: 7579387
Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E.
Smith JD, Trogan E, Ginsberg M, Grigaux C, Tian J, Miyata M
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7667279
IL-3, IL-5, and granulocyte-macrophage colony-stimulating factor potentiate basophil mediator release stimulated by eosinophil granule major basic protein.
Sarmiento EU, Espiritu BR, Gleich GJ, Thomas LL
J Immunol. 1995
PubMed ID: 7543541
Detection of transcripts and binding sites for colony-stimulating factor-1 during bone development.
Hofstetter W, Wetterwald A, Cecchini MG, Mueller C, Felix R
Bone. 1995
PubMed ID: 8554922
Glucocorticoid-attenuated response genes encode intercellular mediators, including a new C-X-C chemokine.
Smith JB, Herschman HR
J Biol Chem. 1995
PubMed ID: 7622488
Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse.
Nilsson SK, Lieschke GJ, Garcia-Wijnen CC, Williams B, Tzelepis D, Hodgson G, Grail D, Dunn AR, Bertoncello I
Blood. 1995
PubMed ID: 7795257
Cytotoxic antibodies trigger inflammation through Fc receptors.
Clynes R, Ravetch JV
Immunity. 1995
PubMed ID: 7621075
Cloning and expression of unique murine macrophage colony-stimulating factor transcripts.
Pogue-Geile K, Sakakeeny MA, Panza JL, Sell SL, Greenberger JS
Blood. 1995
PubMed ID: 7780134
Regulation of urokinase-type plasminogen activator gene transcription by macrophage colony-stimulating factor.
Stacey KJ, Fowles LF, Colman MS, Ostrowski MC, Hume DA
Mol Cell Biol. 1995
PubMed ID: 7760840
The hematopoietic cytokine, colony-stimulating factor 1, is also a growth factor in the CNS: congenital absence of CSF-1 in mice results in abnormal microglial response and increased neuron vulnerability to injury.
Berezovskaya O, Maysinger D, Fedoroff S
Int J Dev Neurosci. 1995
PubMed ID: 7572282
Role of macrophages and colony-stimulating factor-1 in murine antiglomerular basement membrane glomerulonephritis.
Neugarten J, Feith GW, Assmann KJ, Shan Z, Stanley ER, Schlondorff D
J Am Soc Nephrol. 1995
PubMed ID: 7542490
Osteopetrotic (op/op) mice deficient in macrophages have the ability to mount a normal T-cell-dependent immune response.
Chang MD, Stanley ER, Khalili H, Chisholm O, Pollard JW
Cell Immunol. 1995
PubMed ID: 7704903
Is the osteopetrotic (op/op mutant) mouse completely deficient in expression of macrophage colony-stimulating factor?
Hume DA, Favot P
J Interferon Cytokine Res. 1995
PubMed ID: 7627801
Differential regulation of fyn-associated protein tyrosine kinase activity by macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF).
Li Y, Chen B
J Leukoc Biol. 1995
PubMed ID: 7884321
Microglia in colony-stimulating factor 1-deficient op/op mice.
Blevins G, Fedoroff S
J Neurosci Res. 1995
PubMed ID: 7616613
Colony-stimulating factor-1 injections improve but do not cure skeletal sclerosis in osteopetrotic (op) mice.
Sundquist KT, Cecchini MG, Marks SC
Bone. 1995
PubMed ID: 7742081
Models for the study of cementogenesis.
D'Errico JA, MacNeil RL, Strayhorn CL, Piotrowski BT, Somerman MJ
Connect Tissue Res. 1995
PubMed ID: 7554968
Chromosomal location of the murine anion exchanger genes encoding AE2 and AE3.
White RA, Geissler EN, Adkison LR, Dowler LL, Alper SL, Lux SE
Mamm Genome. 1994
PubMed ID: 7894173
Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse.
Raivich G, Moreno-Flores MT, Möller JC, Kreutzberg GW
Eur J Neurosci. 1994
PubMed ID: 7850025
Colony stimulating factor 1 is required for mammary gland development during pregnancy.
Pollard JW, Hennighausen L
Proc Natl Acad Sci U S A. 1994
PubMed ID: 7937762
The development and establishment of hemopoiesis in fetal and newborn osteopetrotic (op/op) mice.
Nilsson SK, Bertoncello I
Dev Biol. 1994
PubMed ID: 8045348
Mice lacking both macrophage- and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease.
Lieschke GJ, Stanley E, Grail D, Hodgson G, Sinickas V, Gall JA, Sinclair RA, Dunn AR
Blood. 1994
PubMed ID: 8018921
Role of colony-stimulating factor-1 in bone metabolism.
Felix R, Hofstetter W, Wetterwald A, Cecchini MG, Fleisch H
J Cell Biochem. 1994
PubMed ID: 7962166
Bacterial translocation and lipopolysaccharide-induced mortality in genetically macrophage-deficient op/op mice.
Feltis BA, Jechorek RP, Erlandsen SL, Wells CL
Shock. 1994
PubMed ID: 7735981
Phospholipase D is activated by phorbol ester but not CSF-1 in murine bone marrow-derived macrophages.
Jaworowski A, Argyriou S, Yusoff P, Hamilton JA
Biochem Biophys Res Commun. 1994
PubMed ID: 8003009
Cytokines in the central nervous system: expression of macrophage colony stimulating factor and its receptor during development.
Chang Y, Albright S, Lee F
J Neuroimmunol. 1994
PubMed ID: 8207122
The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
Takahashi K, Naito M, Umeda S, Shultz LD
Am J Pathol. 1994
PubMed ID: 8203474
Macrophage colony-stimulating factor-induced bone marrow macrophages do not synthesize or release prostaglandin E2.
Shibata Y, Bjorkman DR, Schmidt M, Oghiso Y, Volkman A
Blood. 1994
PubMed ID: 8193367
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse.
Cecchini MG, Dominguez MG, Mocci S, Wetterwald A, Felix R, Fleisch H, Chisholm O, Hofstetter W, Pollard JW, Stanley ER
Development. 1994
PubMed ID: 8050349
Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activi
Takahashi K, Umeda S, Shultz LD, Hayashi S, Nishikawa S
J Leukoc Biol. 1994
PubMed ID: 8182336
Age-related changes in extramedullary hematopoiesis in the spleen of normal and perturbed osteopetrotic (op/op) mice.
Nilsson SK, Bertoncello I
Exp Hematol. 1994
PubMed ID: 8150037
Granulocyte-macrophage colony-stimulating factor corrects macrophage deficiencies, but not osteopetrosis, in the colony-stimulating factor-1-deficient op/op mouse.
Wiktor-Jedrzejczak W, Urbanowska E, Szperl M
Endocrinology. 1994
PubMed ID: 8137761
Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.
Lock LF, Gilbert DJ, Street VA, Migeon MB, Jenkins NA, Copeland NG, Tempel BL
Genomics. 1994
PubMed ID: 8034307
Pivotal role of colony stimulating factor-1 in lupus nephritis.
Rubin Kelley V, Bloom RD, Yui MA, Martin C, Price D
Kidney Int Suppl. 1994
PubMed ID: 8158905
Colony stimulating factor-1 expression in human glioma.
Alterman RL, Stanley ER
Mol Chem Neuropathol. 1994
PubMed ID: 8086034
Ultrastructure of macrophages and dendritic cells in osteopetrosis (op) mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1) activity.
Usuda H, Naito M, Umeda S, Takahashi K, Shultz LD
J Submicrosc Cytol Pathol. 1994
PubMed ID: 8149328
GM-CSF and CSF-1 stimulate DNA synthesis but not cell proliferation in short-term cultures of mid-gestation murine trophoblast.
Drake BL, Head JR
J Reprod Immunol. 1994
PubMed ID: 8040836
The biology and action of colony stimulating factor-1.
Stanley ER, Berg KL, Einstein DB, Lee PS, Yeung YG
Stem Cells. 1994
PubMed ID: 7696959
The effect of activating mutations on dimerization, tyrosine phosphorylation and internalization of the macrophage colony stimulating factor receptor.
Carlberg K, Rohrschneider L
Mol Biol Cell. 1994
PubMed ID: 7514458
Immune cell defects affect bone remodelling in osteopetrotic op/op mice.
Philippart C, Tzehoval E, Moricard Y, Bringuier AF, Seebold C, Lemoine FM, Arys A, Dourov N, Labat ML
Bone Miner. 1993
PubMed ID: 8148672
Transgenic mice in the study of cytokine function.
Taverne J
Int J Exp Pathol. 1993
PubMed ID: 7507352
TGF-beta 2 gene and protein expression in maternal and fetal tissues at various stages of murine development.
Cheng HL, Schneider SL, Kane CM, Gollnick SO, Grande C, Thompson D, Pietrzak E, Tomasi TB
J Reprod Immunol. 1993
PubMed ID: 8164195
Normal distribution of tumor necrosis factor-alpha messenger ribonucleic acid and protein in the uteri, placentas, and embryos of osteopetrotic (op/op) mice lacking colony-stimulating factor-1.
Hunt JS, Chen HL, Hu XL, Pollard JW
Biol Reprod. 1993
PubMed ID: 8399834
Experimental studies of osteopetrosis in laboratory animals.
Seifert MF, Popoff SN, Jackson ME, MacKay CA, Cielinski M, Marks SC
Clin Orthop Relat Res. 1993
PubMed ID: 8358920
Identification of the ligand-binding regions in the macrophage colony-stimulating factor receptor extracellular domain.
Wang ZE, Myles GM, Brandt CS, Lioubin MN, Rohrschneider L
Mol Cell Biol. 1993
PubMed ID: 8355686
Isolation and characterization of a cDNA clone encoding for rat CSF-1 gene. Post-transcriptional repression occurs in myogenic differentiation.
Borycki A, Lenormund J, Guillier M, Leibovitch SA
Biochim Biophys Acta. 1993
PubMed ID: 8357831
The structure of recombinant human carboxy-terminal-truncated macrophage colony-stimulating factor derived from mammalian cells.
Yamanishi K, Yasuda S, Masui Y, Nishida T, Shindo Y, Takano M, Ohmoto Y, Takahashi M, Adachi M
J Biochem. 1993
PubMed ID: 8262907
Analysis of the synergistic stimulation of mouse macrophage proliferation by macrophage colony-stimulating factor (CSF-1) and tumor necrosis factor alpha (TNF-alpha).
Guilbert LJ, Winkler-Lowen B, Smith A, Branch DR, Garcia-Lloret M
J Leukoc Biol. 1993
PubMed ID: 8336080
Colony stimulating factor-1 in the induction of lupus nephritis.
Bloom RD, Florquin S, Singer GG, Brennan DC, Kelley VR
Kidney Int. 1993
PubMed ID: 8510378
Combination macrophage-colony stimulating factor and interferon-gamma administration ameliorates the osteopetrotic condition in microphthalmic (mi/mi) mice.
Rodriguiz RM, Key LL, Ries WL
Pediatr Res. 1993
PubMed ID: 8479820
Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse.
Witmer-Pack MD, Hughes DA, Schuler G, Lawson L, McWilliam A, Inaba K, Steinman RM, Gordon S
J Cell Sci. 1993
PubMed ID: 8314887
Assignment of the inter- and intramolecular disulfide linkages in recombinant human macrophage colony stimulating factor using fast atom bombardment mass spectrometry.
Glocker MO, Arbogast B, Schreurs J, Deinzer ML
Biochemistry. 1993
PubMed ID: 8422357
Macrophage colon-stimulating factor (M-CSF) is essential for differentiation rather than proliferation of osteoclast progenitors.
Suda T, Tanaka S, Takahashi N
Osteoporos Int. 1993
PubMed ID: 8461535
Transient recruitment of osteoclasts and expression of their function in osteopetrotic (op/op) mice by a single injection of macrophage colony-stimulating factor.
Kodama H, Yamasaki A, Abe M, Niida S, Hakeda Y, Kawashima H
J Bone Miner Res. 1993
PubMed ID: 8427048
Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Takahashi K, Naito M, Shultz LD, Hayashi S, Nishikawa S
J Leukoc Biol. 1993
PubMed ID: 8426088
Delayed hematopoietic development in osteopetrotic (op/op) mice.
Begg SK, Radley JM, Pollard JW, Chisholm OT, Stanley ER, Bertoncello I
J Exp Med. 1993
PubMed ID: 8418205
Immunophenotypic and ultrastructural differentiation and maturation of nonlymphoid dendritic cells in osteopetrotic (op) mice with the total absence of macrophage colony stimulating factor activity.
Takahashi K, Naito M, Morioka Y, Schultz LD
Adv Exp Med Biol. 1993
PubMed ID: 8379385
Developmental regulation of cytokine expression in the mouse brain.
Burns TM, Clough JA, Klein RM, Wood GW, Berman NE
Growth Factors. 1993
PubMed ID: 8148154
Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system.
Gout I, Dhand R, Panayotou G, Fry MJ, Hiles I, Otsu M, Waterfield MD
Biochem J. 1992
PubMed ID: 1334406
Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.
Pandit J, Bohm A, Jancarik J, Halenbeck R, Koths K, Kim SH
Science. 1992
PubMed ID: 1455231
Differentiation of epidermal Langerhans cells in macrophage colony-stimulating-factor-deficient mice homozygous for the osteopetrosis (op) mutation.
Takahashi K, Naito M, Shultz LD
J Invest Dermatol. 1992
PubMed ID: 1431208
A study of granulated metrial gland cell differentiation in pregnant, macrophage-deficient, osteopetrotic (op/op) mice.
Kiso Y, Pollard JW, Croy BA
Experientia. 1992
PubMed ID: 1426147
CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages.
Wiktor-Jedrzejczak W, Ratajczak MZ, Ptasznik A, Sell KW, Ahmed-Ansari A, Ostertag W
Exp Hematol. 1992
PubMed ID: 1505635
Distinct in vivo functions of two macrophage subpopulations as evidenced by studies using macrophage-deficient op/op mouse.
Wiktor-Jedrzejczak W, Ansari AA, Szperl M, Urbanowska E
Eur J Immunol. 1992
PubMed ID: 1378025
Macrophage colony-stimulating factor is produced by activated T lymphocytes in vitro and is detected in vivo in T cells from reactive lymph nodes.
Praloran V, Chevalier S, Gascan H
Blood. 1992
PubMed ID: 1571567
Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development.
Arceci RJ, Pampfer S, Pollard JW
Dev Biol. 1992
PubMed ID: 1374350
Epidermal growth factor stimulates macrophage colony-stimulating factor (M-CSF) mRNA expression and M-CSF release in cultured murine stromal cells.
Abboud SL
Br J Haematol. 1992
PubMed ID: 1581229
Identification of a high molecular weight macrophage colony-stimulating factor as a glycosaminoglycan-containing species.
Suzu S, Ohtsuki T, Yanai N, Takatsu Z, Kawashima T, Takaku F, Nagata N, Motoyoshi K
J Biol Chem. 1992
PubMed ID: 1531650
Reassignment of the human macrophage colony stimulating factor gene to chromosome 1p13-21.
Saltman DL, Dolganov GM, Hinton LM, Lovett M
Biochem Biophys Res Commun. 1992
PubMed ID: 1540160
The predominant form of secreted colony stimulating factor-1 is a proteoglycan.
Price LK, Choi HU, Rosenberg L, Stanley ER
J Biol Chem. 1992
PubMed ID: 1733926
Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis.
Clinton SK, Underwood R, Hayes L, Sherman ML, Kufe DW, Libby P
Am J Pathol. 1992
PubMed ID: 1739124
Expression of colony-stimulating factors and inflammatory cytokines in the uterus of CD1 mice during days 1 to 3 of pregnancy.
Sanford TR, De M, Wood GW
J Reprod Fertil. 1992
PubMed ID: 1552482
Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1.
Pampfer S, Tabibzadeh S, Chuan FC, Pollard JW
Mol Endocrinol. 1991
PubMed ID: 1791839
Mitogenic response to colony-stimulating factor 1.
Sherr CJ
Trends Genet. 1991
PubMed ID: 1840317
A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility.
Pollard JW, Hunt JS, Wiktor-Jedrzejczak W, Stanley ER
Dev Biol. 1991
PubMed ID: 1834496
Reassignment of the human CSF1 gene to chromosome 1p13-p21.
Morris SW, Valentine MB, Shapiro DN, Sublett JE, Deaven LL, Foust JT, Roberts WM, Cerretti DP, Look AT
Blood. 1991
PubMed ID: 1912583
Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin.
Owens GC, Bunge RP
Neuron. 1991
PubMed ID: 1718333
Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor.
Naito M, Hayashi S, Yoshida H, Nishikawa S, Shultz LD, Takahashi K
Am J Pathol. 1991
PubMed ID: 1887865
Cloning and characterization of the murine promoter for the colony-stimulating factor-1-encoding gene.
Harrington MA, Edenberg HJ, Saxman S, Pedigo LM, Daub R, Broxmeyer HE
Gene. 1991
PubMed ID: 1874443
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle.
Matsushime H, Roussel MF, Ashmun RA, Sherr CJ
Cell. 1991
PubMed ID: 1827757
Colony stimulating factor 1 (CSF-1) and its in vivo role as delineated using osteopetrotic op/op mice.
Wiktor-Jedrzejczak W
Postepy Biochem. 1991
PubMed ID: 1840281
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse.
Felix R, Cecchini MG, Fleisch H
Endocrinology. 1990
PubMed ID: 2146111
Direct stimulation of cells expressing receptors for macrophage colony-stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1.
Stein J, Borzillo GV, Rettenmier CW
Blood. 1990
PubMed ID: 2145044
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.
Wiktor-Jedrzejczak W, Bartocci A, Ferrante AW, Ahmed-Ansari A, Sell KW, Pollard JW, Stanley ER
Proc Natl Acad Sci U S A. 1990
PubMed ID: 2191302
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene.
Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H, Sudo T, Shultz LD, Nishikawa S
Nature. 1990
PubMed ID: 2188141
Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development.
Arceci RJ, Shanahan F, Stanley ER, Pollard JW
Proc Natl Acad Sci U S A. 1989
PubMed ID: 2554332
Localization of the murine macrophage colony-stimulating factor gene to chromosome 3 using interspecific backcross analysis.
Buchberg AM, Jenkins NA, Copeland NG
Genomics. 1989
PubMed ID: 2676841
Amino-terminal region of human macrophage colony-stimulating factor (M-CSF) is sufficient for its in vitro biological activity: molecular cloning and expression of carboxyl-terminal deletion mutants of human M-CSF.
Takahashi M, Hirato T, Takano M, Nishida T, Nagamura K, Kamogashira T, Nakai S, Hirai Y
Biochem Biophys Res Commun. 1989
PubMed ID: 2660794
The murine M-CSF gene is localized on chromosome 3.
Gisselbrecht S, Sola B, Fichelson S, Bordereaux D, Tambourin P, Mattei MG, Simon D, Guenet JL
Blood. 1989
PubMed ID: 2565740
Expression and processing of a recombinant human macrophage colony-stimulating factor in mouse cells.
Manos MM
Mol Cell Biol. 1988
PubMed ID: 3264878
Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs.
Rettenmier CW, Roussel MF
Mol Cell Biol. 1988
PubMed ID: 3264877
Integration of the BALB/c ecotropic provirus into the colony-stimulating factor-1 growth factor locus in a myc retrovirus-induced murine monocyte tumor.
Baumbach WR, Colston EM, Cole MD
J Virol. 1988
PubMed ID: 3261346
cDNA cloning and expression of murine macrophage colony-stimulating factor from L929 cells.
Ladner MB, Martin GA, Noble JA, Wittman VP, Warren MK, McGrogan M, Stanley ER
Proc Natl Acad Sci U S A. 1988
PubMed ID: 2457916
Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.
Cerretti DP, Wignall J, Anderson D, Tushinski RJ, Gallis BM, Stya M, Gillis S, Urdal DL, Cosman D
Mol Immunol. 1988
PubMed ID: 2460758
Macrophage colony-stimulating factor is produced by human T lymphoblastoid cell line, CEM-ON: identification by amino-terminal amino acid sequence analysis.
Takahashi M, Hong YM, Yasuda S, Takano M, Kawai K, Nakai S, Hirai Y
Biochem Biophys Res Commun. 1988
PubMed ID: 3259875
Macrophage colony-stimulating factor purified from normal human urine. Amino-terminal sequence and amino acid composition.
Sakai N, Umeda T, Suzuki H, Ishimatsu Y, Shikita M
FEBS Lett. 1987
PubMed ID: 3498652
Human CSF-1: gene structure and alternative splicing of mRNA precursors.
Ladner MB, Martin GA, Noble JA, Nikoloff DM, Tal R, Kawasaki ES, White TJ
EMBO J. 1987
PubMed ID: 3500041
Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.
Rettenmier CW, Roussel MF, Ashmun RA, Ralph P, Price K, Sherr CJ
Mol Cell Biol. 1987
PubMed ID: 3039346
Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.
Wong GG, Temple PA, Leary AC, Witek-Giannotti JS, Yang YC, Ciarletta AB, Chung M, Murtha P, Kriz R, Kaufman RJ
Science. 1987
PubMed ID: 3493529
Nucleotide sequence of a cDNA encoding murine CSF-1 (Macrophage-CSF).
DeLamarter JF, Hession C, Semon D, Gough NM, Rothenbuhler R, Mermod JJ
Nucleic Acids Res. 1987
PubMed ID: 3494232
Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA.
Rajavashisth TB, Eng R, Shadduck RK, Waheed A, Ben-Avram CM, Shively JE, Lusis AJ
Proc Natl Acad Sci U S A. 1987
PubMed ID: 3493488
Induction of clonal monocyte-macrophage tumors in vivo by a mouse c-myc retrovirus: rearrangement of the CSF-1 gene as a secondary transforming event.
Baumbach WR, Stanley ER, Cole MD
Mol Cell Biol. 1987
PubMed ID: 3547079
The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors.
Metcalf D
Blood. 1986
PubMed ID: 3002522
Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1).
Kawasaki ES, Ladner MB, Wang AM, Van Arsdell J, Warren MK, Coyne MY, Schweickart VL, Lee MT, Wilson KJ, Boosman A
Science. 1985
PubMed ID: 2996129
The granulocyte-macrophage colony-stimulating factors.
Metcalf D
Science. 1985
PubMed ID: 2990035
Amino-terminal amino acid sequence of murine colony-stimulating factor 1.
Ben-Avram CM, Shively JE, Shadduck RK, Waheed A, Rajavashisth T, Lusis AJ
Proc Natl Acad Sci U S A. 1985
PubMed ID: 3925458
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.
Sherr CJ, Rettenmier CW, Sacca R, Roussel MF, Look AT, Stanley ER
Cell. 1985
PubMed ID: 2408759
Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiation.
Wiktor-Jedrzejczak WW, Ahmed A, Szczylik C, Skelly RR
J Exp Med. 1982
PubMed ID: 7130905
Gene order in linkage group XVI of the house mouse.
Lane PW, Eicher EM
J Hered. 1979
PubMed ID: 489953
Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse.
Marks SC, Lane PW
J Hered. 1976
PubMed ID: 1262696
Nodisjunction and reduced fertility caused by the tobacco mouse metacentric chromosomes.
Cattanach BM, Moseley H
Cytogenet Cell Genet. 1973
PubMed ID: 4796241
Esterase genetics in Mus musculus: expression, linkage, and polymorphism of locus Es-2.
Ruddle FH, Shows TB, Roderick TH
Genetics. 1969
PubMed ID: 5372803

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	1435	12977	78965
EnsEMBL Gene(s)	ENSG00000184371	ENSMUSG00000014599	ENSRNOG00000018659
Unigene	Hs.173894	Mm.795	Rn.83632
Homologene	CSF1	Csf1	Csf1
OMIM	120420	N/A	N/A
GeneCards	CSF1	N/A	N/A
Beta Cell Genomics	DT.100772555 DT.100784442 DT.440766 DT.86846409 DT.99929429	DT.101312104 DT.111042454 DT.94133549 DT.94150590	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	ENSP00000327513	N/A	N/A
WikiGenes	1435	12977	78965

External resources from NIDDK Consortium Interconnectivity Network Top Help

Relevant resources:

View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
CSF1	RGS14	IntAct	empirical	16267818
CSF1	CAMKK2	IntAct	empirical	16267818
CSF1	GAB3	HPRD	empirical	11739737
CSF1	SIRPA	IntAct	empirical	16267818
CSF1	CSF1	HPRD	empirical	1733926 8422357
CSF1	CSF1R	HPRD, BioGRID	empirical	2408759 8355686
CSF1	DYNC1H1	IntAct	empirical	16267818
CSF1	EEF1A1	IntAct	empirical	16267818
CSF1	EEF1G	IntAct	empirical	16267818
CSF1	CELSR3	IntAct	empirical	16267818
CSF1	MARK2	IntAct	empirical	16267818
CSF1	AK1	IntAct	empirical	16267818
CSF1	FLNB	IntAct	empirical	16267818
CSF1	MAPK8IP2	IntAct	empirical	16267818
CSF1	GAPDH	IntAct	empirical	16267818
CSF1	C20orf4	IntAct	empirical	16267818
CSF1	MKNK2	IntAct	empirical	16267818
CSF1	ANXA1	IntAct	empirical	16267818
CSF1	HLA-B	HPRD	empirical	15494511
CSF1	JAK2	IntAct	empirical	16267818
CSF1	MAP3K3	IntAct	empirical	16267818
CSF1	MAP3K5	IntAct	empirical	16267818
CSF1	MYC	IntAct	empirical	21150319
CSF1	MYD88	IntAct	empirical	16267818
CSF1	MYH9	IntAct	empirical	16267818
CSF1	MYH10	IntAct	empirical	16267818
CSF1	MYH11	IntAct	empirical	16267818
CSF1	MYO1A	IntAct	empirical	16267818
CSF1	MYO1C	IntAct	empirical	16267818
CSF1	MYO5A	IntAct	empirical	16267818
CSF1	OPA1	IntAct	empirical	16267818
CSF1	CLDN11	IntAct	empirical	16267818
CSF1	PIK3R1	IntAct	empirical	16267818
CSF1	PIK3R2	BioGRID	empirical	1334406
CSF1	PPP1R12C	IntAct	empirical	16267818
CSF1	PPP1R3A	IntAct	empirical	16267818
CSF1	ACTB	IntAct	empirical	16267818
CSF1	MYO1G	IntAct	empirical	16267818
CSF1	SLC7A1	IntAct	empirical	16267818
CSF1	SRC	IntAct	empirical	16267818
CSF1	SYK	IntAct	empirical	16267818
CSF1	ICAM5	IntAct	empirical	16267818
CSF1	TNF	HPRD	empirical	8336080
CSF1	TPM3	IntAct	empirical	16267818
CSF1	UBC	BioGRID	empirical	17353186
CSF1	SOCS1	HPRD	empirical	11297560
CSF1	CBL	BioGRID	empirical	17353186
CSF1	IQGAP1	IntAct	empirical	16267818
CSF1	ITM2B	IntAct	empirical	16267818
CSF1	ROCK2	IntAct	empirical	16267818