CP
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(Human) GRCh37 - chr3:148880197..148939842 (59.65 kb) View in Genome Browser
(Mouse) NCBIM37 - chr3:19857054..19909145 (529 kb) View in Genome Browser
(Rat) RGSC3.4 - chr2:105086278..105145860 (59.58 kb) View in Genome Browser
HaemAtlas Expression Table for CP:
Expression Legend
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Cell Types Showing Expression: Available
Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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| ductal cells | exocrine pancreas | pancreatic islets | primary beta cells | Pancreatic Islets MPSS | beta cell line | pancreatic islets | whole pancreas | alpha cell | beta cell line | pancreatic islets | primary beta cells | whole pancreas |
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The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues.
A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.
Tissues Showing Expression: Available
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| Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions Table for CP:The CP interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction.
The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources.
| Interactor | Interactor | Sources | Classification | Pubmed IDs |
| CP | GAST | HPRD | empirical | 463490 |
| CP | SLC40A1 | IntAct, Reactome | empirical | 20817278 |
| CP | APOA1 | IntAct | empirical | 15174051 |
| CP | IGHG1 | IntAct | empirical | 15174051 |
| CP | LTF | HPRD, BioGRID | empirical | 10666301 |
| CP | MPO | HPRD | empirical | 9097926 |
| CP | PLG | HPRD | empirical | 146197 6582496 |
| CP | ATP7A | HPRD | empirical | 11040994 |
| CP | PROC | HPRD | empirical | 2105310 |
| CP | UBC | BioGRID | empirical | 19850743 |
| CP | BTRC | IntAct | empirical | 21988832 |
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Type 1 Diabetes Publications: 2
-
Evaluation of oxidative stress in Insulin Dependent Diabetes Mellitus (IDDM) patients.
Ramakrishna V, Jailkhani R
Diagn Pathol. 2007
PubMed ID: 17603912
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Characterization of a nonsense mutation in the ceruloplasmin gene resulting in diabetes and neurodegenerative disease.
Takahashi Y, Miyajima H, Shirabe S, Nagataki S, Suenaga A, Gitlin JD
Hum Mol Genet. 1996
PubMed ID: 8789443
Publications: 205
-
Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF.
Texel SJ, Camandola S, Ladenheim B, Rothman SM, Mughal MR, Unger EL, Cadet JL, Mattson MP
J Neurochem. 2012
PubMed ID: 22035068
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Plasma ceruloplasmin ferroxidase activity correlates with the nigral sonographic area in Parkinson's disease patients: a pilot study.
Martínez-Hernández R, Montes S, Higuera-Calleja J, Yescas P, Boll MC, Diaz-Ruiz A, Rios C
Neurochem Res. 2011
PubMed ID: 21706376
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Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake.
Ranganathan PN, Lu Y, Jiang L, Kim C, Collins JF
Blood. 2011
PubMed ID: 21768302
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A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
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Ceruloplasmin expression in rat liver cells is attenuated by insulin: role of FoxO transcription factors.
Leyendecker M, Korsten P, Reinehr R, Speckmann B, Schmoll D, Scherbaum WA, Bornstein SR, Barthel A, Klotz LO
Horm Metab Res. 2011
PubMed ID: 21332026
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DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, Misra S, Chaudhuri G, Buaas FW, Braun RE, Hinton DR, Zhang Q, Grossniklaus HE, Provis JM, Madigan MC, Milam AH, Justice NL, Albuquerque RJ, Blandford AD, Bogdanovich S, Hirano Y, Witta J, Fuchs E, Littman DR, Ambati BK, Rudin CM, Chong MM, Provost P, Kugel JF, Goodrich JA, Dunaief JL, Baffi JZ, Ambati J
Nature. 2011
PubMed ID: 21297615
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The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration.
Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Grieco S, Lee J, Lyubarsky A, Pratico D, Connelly J, Spino M, Harris ZL, Dunaief JL
Invest Ophthalmol Vis Sci. 2011
PubMed ID: 21051716
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FOXO1 stimulates ceruloplasmin promoter activity in human hepatoma cells treated with IL-6.
Sidhu A, Miller PJ, Hollenbach AD
Biochem Biophys Res Commun. 2011
PubMed ID: 21185807
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Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke.
Texel SJ, Zhang J, Camandola S, Unger EL, Taub DD, Koehler RC, Harris ZL, Mattson MP
PLoS One. 2011
PubMed ID: 21949858
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
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Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson's disease.
Jin L, Wang J, Zhao L, Jin H, Fei G, Zhang Y, Zeng M, Zhong C
Brain. 2011
PubMed ID: 21109502
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Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice.
Hadziahmetovic M, Song Y, Ponnuru P, Iacovelli J, Hunter A, Haddad N, Beard J, Connor JR, Vaulont S, Dunaief JL
Invest Ophthalmol Vis Sci. 2011
PubMed ID: 20811044
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Interaction of ceruloplasmin and 5-lipoxygenase.
Sokolov AV, Golenkina EA, Kostevich VA, Vasilyev VB, Sud'ina GF
Biochemistry (Mosc). 2010
PubMed ID: 21314617
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Hepatic but not brain iron is rapidly chelated by deferasirox in aceruloplasminemia due to a novel gene mutation.
Finkenstedt A, Wolf E, Höfner E, Gasser BI, Bösch S, Bakry R, Creus M, Kremser C, Schocke M, Theurl M, Moser P, Schranz M, Bonn G, Poewe W, Vogel W, Janecke AR, Zoller H
J Hepatol. 2010
PubMed ID: 20801540
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Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin.
Kono S, Yoshida K, Tomosugi N, Terada T, Hamaya Y, Kanaoka S, Miyajima H
Biochim Biophys Acta. 2010
PubMed ID: 20655381
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Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells.
Chen H, Attieh ZK, Syed BA, Kuo YM, Stevens V, Fuqua BK, Andersen HS, Naylor CE, Evans RW, Gambling L, Danzeisen R, Bacouri-Haidar M, Usta J, Vulpe CD, McArdle HJ
J Nutr. 2010
PubMed ID: 20685892
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Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Tevfik Dorak M
Mol Hum Reprod. 2010
PubMed ID: 20587610
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Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI
Cell. 2010
PubMed ID: 20817278
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Interactions of caeruloplasmin with other proteins participating in inflammation.
Vasilyev VB
Biochem Soc Trans. 2010
PubMed ID: 20658982
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Evidence for a critical role of ceruloplasmin oxidase activity in iron metabolism of Wilson disease gene knockout mice.
Merle U, Tuma S, Herrmann T, Muntean V, Volkmann M, Gehrke SG, Stremmel W
J Gastroenterol Hepatol. 2010
PubMed ID: 20594231
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Ceruloplasmin-induced aggregation of P19 neurons involves a serine protease activity and is accompanied by reelin cleavage.
Ducharme P, Maltais D, Desroches D, Mateescu MA, Paquin J
Neuroscience. 2010
PubMed ID: 20188154
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Levels of plasma ceruloplasmin protein are markedly lower following dietary copper deficiency in rodents.
Broderius M, Mostad E, Wendroth K, Prohaska JR
Comp Biochem Physiol C Toxicol Pharmacol. 2010
PubMed ID: 20170749
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Increased oxidized low density lipoprotein associated with high ceruloplasmin activity in patients with active acromegaly.
Boero L, Cuniberti L, Magnani N, Manavela M, Yapur V, Bustos M, Rosso LG, Meroño T, Marziali L, Viale L, Evelson P, Negri G, Brites F
Clin Endocrinol (Oxf). 2010
PubMed ID: 19681912
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Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats.
Mizukami S, Ichimura R, Kemmochi S, Taniai E, Shimamoto K, Ohishi T, Takahashi M, Mitsumori K, Shibutani M
Arch Toxicol. 2010
PubMed ID: 20091025
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Identification of human plasma proteins as major clients for the extracellular chaperone clusterin.
Wyatt AR, Wilson MR
J Biol Chem. 2010
PubMed ID: 19996109
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Increased ceruloplasmin and fibrinogen in type 2 diabetes corresponds to decreased anti-oxidant activity in a preliminary tertiary South Indian hospital study.
Chacko SK, Cheluvappa R
Exp Clin Endocrinol Diabetes. 2010
PubMed ID: 19834873
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Ferritin ferroxidase activity: a potent inhibitor of osteogenesis.
Zarjou A, Jeney V, Arosio P, Poli M, Zavaczki E, Balla G, Balla J
J Bone Miner Res. 2010
PubMed ID: 19821764
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TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.
Vanderwerf SM, Svahn J, Olson S, Rathbun RK, Harrington C, Yates J, Keeble W, Anderson DC, Anur P, Pereira NF, Pilonetto DV, Pasquini R, Bagby GC
Blood. 2009
PubMed ID: 19850743
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Diurnal changes in urinary excretion of IgG, transferrin, and ceruloplasmin depend on diurnal changes in systemic blood pressure in normotensive, normoalbuminuric type 2 diabetic patients.
Hosoba M, Fujita H, Miura T, Morii T, Shimotomai T, Koshimura J, Yamada Y, Ito S, Narita T
Horm Metab Res. 2009
PubMed ID: 19670106
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Study of interaction of ceruloplasmin, lactoferrin, and myeloperoxidase by photon correlation spectroscopy.
Sokolov AV, Prozorovskii VN, Vasilyev VB
Biochemistry (Mosc). 2009
PubMed ID: 19916937
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Enrichment of glycopeptides for glycan structure and attachment site identification.
Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G
Nat Methods. 2009
PubMed ID: 19838169
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Computational modeling of the dizinc-ferroxidase complex of human H ferritin: direct comparison of the density functional theory calculated and experimental structures.
Binning RC, Bacelo DE
J Biol Inorg Chem. 2009
PubMed ID: 19585161
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Lipid profile, low-density lipoprotein oxidation and ceruloplasmin in the progeny of families with a positive history of cardiovascular diseases and/or hyperlipidemia.
Makedou KG, Mikhailidis DP, Makedou A, Iliadis S, Kourtis A, Vavatsi-Christaki N, Papageorgiou GE
Angiology. 2009
PubMed ID: 19648144
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Differential impact of copper deficiency in rats on blood cuproproteins.
Broderius MA, Prohaska JR
Nutr Res. 2009
PubMed ID: 19700037
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Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
-
A novel and one-step purification of human ceruloplasmin by acharan sulfate affinity chromatography.
Park Y, Lee IS, Joo EJ, Hahn BS, Kim YS
Arch Pharm Res. 2009
PubMed ID: 19471883
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Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model.
Woo GH, Takahashi M, Inoue K, Fujimoto H, Igarashi K, Kanno J, Hirose M, Nishikawa A, Shibutani M
Cancer Sci. 2009
PubMed ID: 19298605
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Ceruloplasmin/Transferrin system is related to clinical status in acute stroke.
Altamura C, Squitti R, Pasqualetti P, Gaudino C, Palazzo P, Tibuzzi F, Lupoi D, Cortesi M, Rossini PM, Vernieri F
Stroke. 2009
PubMed ID: 19228837
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Methanolic extract of Ruta graveolens L. inhibits inflammation and oxidative stress in adjuvant induced model of arthritis in rats.
Ratheesh M, Shyni GL, Helen A
Inflammopharmacology. 2009
PubMed ID: 19205849
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Copper proteins and ferroxidases in human plasma and that of wild-type and ceruloplasmin knockout mice.
Gray LW, Kidane TZ, Nguyen A, Akagi S, Petrasek K, Chu YL, Cabrera A, Kantardjieff K, Mason AZ, Linder MC
Biochem J. 2009
PubMed ID: 19076073
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[Regulation of ceruloplasmin gene activity in mammary gland cells]
Tsymbalenko NV, Giulikhandanova NE, Platononova NA, Babich VS, Evsiukova II, Puchkova LV
Genetika. 2009
PubMed ID: 19382692
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The oxidative response in the chronic constriction injury model of neuropathic pain.
Tan EC, Bahrami S, Kozlov AV, Kurvers HA, Ter Laak HJ, Nohl H, Redl H, Goris RJ
J Surg Res. 2009
PubMed ID: 18708193
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Dominant mutants of ceruloplasmin impair the copper loading machinery in aceruloplasminemia.
di Patti MC, Maio N, Rizzo G, De Francesco G, Persichini T, Colasanti M, Polticelli F, Musci G
J Biol Chem. 2009
PubMed ID: 19095659
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Efficacy of grape seed proanthocyanidins on cardioprotection during isoproterenol-induced myocardial injury in rats.
Karthikeyan K, Bai BR, Devaraj SN
J Cardiovasc Pharmacol. 2009
PubMed ID: 19188839
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Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
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Ceruloplasmin is a better predictor of the long-term prognosis compared with fibrinogen, CRP, and IL-6 in patients with severe unstable angina.
Ziakas A, Gavrilidis S, Souliou E, Giannoglou G, Stiliadis I, Karvounis H, Efthimiadis G, Mochlas S, Vayona MA, Hatzitolios A, Savopoulos C, Pidonia I, Parharidis G
Angiology. 2009
PubMed ID: 18388036
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Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases.
Tapryal N, Mukhopadhyay C, Das D, Fox PL, Mukhopadhyay CK
J Biol Chem. 2009
PubMed ID: 19019832
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Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson's disease.
Bharucha KJ, Friedman JK, Vincent AS, Ross ED
J Neurol. 2008
PubMed ID: 19159062
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Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ
Mech Ageing Dev. 2008
PubMed ID: 18977241
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Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice.
Kaneko K, Hineno A, Yoshida K, Ikeda S
Neurosci Lett. 2008
PubMed ID: 18804145
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Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.
Rathore KI, Kerr BJ, Redensek A, López-Vales R, Jeong SY, Ponka P, David S
J Neurosci. 2008
PubMed ID: 19036966
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Pro- and antioxidants in the central lymph in experimental chronic toxic hepatitis.
Borodin JI, Bashkirova JV, Lyubarsky MS, Kolpakov MA
Bull Exp Biol Med. 2008
PubMed ID: 19526092
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Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other.
Sokolov AV, Ageeva KV, Pulina MO, Cherkalina OS, Samygina VR, Vlasova II, Panasenko OM, Zakharova ET, Vasilyev VB
Free Radic Res. 2008
PubMed ID: 19031316
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Hyaluronan regulates ceruloplasmin production by gliomas and their treatment-resistant multipotent progenitors.
Tye SL, Gilg AG, Tolliver LB, Wheeler WG, Toole BP, Maria BL
J Child Neurol. 2008
PubMed ID: 18952589
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Placental expression of ceruloplasmin in pregnancies complicated by severe preeclampsia.
Guller S, Buhimschi CS, Ma YY, Huang ST, Yang L, Kuczynski E, Zambrano E, Lockwood CJ, Buhimschi IA
Lab Invest. 2008
PubMed ID: 18679377
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Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases.
Boll MC, Alcaraz-Zubeldia M, Montes S, Rios C
Neurochem Res. 2008
PubMed ID: 18307039
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Multiple motor system dysfunction associated with a heterozygous ceruloplasmin gene mutation.
Jiménez-Huete A, Bernar J, Miyajima H, Takahashi Y, Alvarez-Linera J, Franch O, van der Knaap MS
J Neurol. 2008
PubMed ID: 18293024
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Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.
Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL
Invest Ophthalmol Vis Sci. 2008
PubMed ID: 18326691
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Features of ceruloplasmin in the cerebrospinal fluid of Alzheimer's disease patients.
Capo CR, Arciello M, Squitti R, Cassetta E, Rossini PM, Calabrese L, Rossi L
Biometals. 2008
PubMed ID: 18060472
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High brain iron level in asymptomatic carriers of heterozygous ceruloplasmin gene mutations.
Chen Q, Chen XP, Zou L, Zhou D, Gong QY, Burgunder JM, Shang HF
Mov Disord. 2008
PubMed ID: 18311828
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Aceruloplasminemia: a novel mutation in a family with marked phenotypic variability.
Fasano A, Colosimo C, Miyajima H, Tonali PA, Re TJ, Bentivoglio AR
Mov Disord. 2008
PubMed ID: 18200628
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Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin.
Hudson DM, Krisinger MJ, Griffiths TA, Macgillivray RT
J Cell Biochem. 2008
PubMed ID: 18022819
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Transcripts of ceruloplasmin but not hepcidin, both major iron metabolism genes, exhibit a decreasing pattern along the portocentral axis of mouse liver.
Troadec MB, Fautrel A, Drénou B, Leroyer P, Camberlein E, Turlin B, Guillouzo A, Brissot P, Loréal O
Biochim Biophys Acta. 2008
PubMed ID: 18222182
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The measurement of serum ceruloplasmin is useful for diagnostic differentiation of immune thrombocytopenic purpura.
Chousa M, Ito H, Saito K, Takahashi K, Takemura M, Takahashi T, Tomita E, Seishima M
Clin Chim Acta. 2008
PubMed ID: 18187043
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Role of copper in thermal stability of human ceruloplasmin.
Sedlák E, Zoldák G, Wittung-Stafshede P
Biophys J. 2008
PubMed ID: 17965133
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An inhibition of ceruloplasmin expression induced by cerebral ischemia in the cortex and hippocampus of rats.
Li YW, Li L, Zhao JY
Neurosci Bull. 2008
PubMed ID: 18273071
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Ceruloplasmin expression by human peripheral blood lymphocytes: a new link between immunity and iron metabolism.
Banha J, Marques L, Oliveira R, Martins Mde F, Paixão E, Pereira D, Malhó R, Penque D, Costa L
Free Radic Biol Med. 2008
PubMed ID: 17991445
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Ceruloplasmin fragmentation is implicated in 'free' copper deregulation of Alzheimer's disease.
Squitti R, Quattrocchi CC, Salustri C, Rossini PM
Prion. 2008
PubMed ID: 19164917
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Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.
Imami K, Sugiyama N, Kyono Y, Tomita M, Ishihama Y
Anal Sci. 2008
PubMed ID: 18187866
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Patterns of correlation of plasma ceruloplasmin in sepsis.
Chiarla C, Giovannini I, Siegel JH
J Surg Res. 2008
PubMed ID: 17688883
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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
Cell. 2007
PubMed ID: 18083107
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Cys-881 is essential for the trafficking and secretion of truncated mutant ceruloplasmin in aceruloplasminemia.
Kono S, Suzuki H, Oda T, Shirakawa K, Takahashi Y, Kitagawa M, Miyajima H
J Hepatol. 2007
PubMed ID: 17637479
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Hyperthyroidism is associated with increased aortic oxidative DNA damage in a rat model.
Moulakakis KG, Poulakou MV, Paraskevas KI, Dontas I, Vlachos IS, Sokolis DP, Dosios T, Karayannacos PE, Perrea D
In Vivo. 2007
PubMed ID: 18210749
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Structural characterization of the ceruloplasmin: lactoferrin complex in solution.
Sabatucci A, Vachette P, Vasilyev VB, Beltramini M, Sokolov A, Pulina M, Salvato B, Angelucci CB, Maccarrone M, Cozzani I, Dainese E
J Mol Biol. 2007
PubMed ID: 17597152
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Discrete roles of copper ions in chemical unfolding of human ceruloplasmin.
Sedlak E, Wittung-Stafshede P
Biochemistry. 2007
PubMed ID: 17661447
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Neutrophil activation, protein oxidation and ceruloplasmin levels in children with Henoch-Schönlein purpura.
Ece A, Kelekçi S, Hekimoğlu A, Kocamaz H, Balik H, Yolbaş I, Erel O
Pediatr Nephrol. 2007
PubMed ID: 17404760
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Expression of ferroportin1, hephaestin and ceruloplasmin in rat heart.
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Biochim Biophys Acta. 2007
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Neurochem Int. 2007
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Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.
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J Proteome Res. 2007
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Regulation of ceruloplasmin in human hepatic cells by redox active copper: identification of a novel AP-1 site in the ceruloplasmin gene.
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Biochem J. 2007
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Genetic study of variation in normal mouse iron homeostasis reveals ceruloplasmin as an HFE-hemochromatosis modifier gene.
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Gastroenterology. 2007
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Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites.
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Acta Crystallogr D Biol Crystallogr. 2007
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A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
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BMC Genet. 2007
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Genes involved in the balance between neuronal survival and death during inflammation.
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PLoS ONE. 2007
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Novel mutation in the ceruloplasmin gene causing a cognitive and movement disorder with diabetes mellitus.
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Mov Disord. 2006
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Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.
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Invest Ophthalmol Vis Sci. 2006
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Effect of fungal polysaccharides on the modulation of plasma proteins in streptozotocin-induced diabetic rats.
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Proteomics. 2006
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Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice.
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J Neurosci. 2006
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Antioxidant and antibacterial genes are upregulated in early involution of the mouse mammary gland: sharp increase of ceruloplasmin and lactoferrin in accumulating breast milk.
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DNA Cell Biol. 2006
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Proteome-wide characterization of N-glycosylation events by diagonal chromatography.
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J Proteome Res. 2006
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Hepatic iron overload associated with a decreased serum ceruloplasmin level in a novel clinical type of aceruloplasminemia.
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Gastroenterology. 2006
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J Biochem Mol Biol. 2006
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Antioxidant ceruloplasmin is expressed by glomerular parietal epithelial cells and secreted into urine in association with glomerular aging and high-calorie diet.
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J Am Soc Nephrol. 2006
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The DNA sequence, annotation and analysis of human chromosome 3.
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Nature. 2006
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PLoS Biol. 2006
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Consequences of copper accumulation in the livers of the Atp7b-/- (Wilson disease gene) knockout mice.
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Am J Pathol. 2006
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Biochemical features of ceruloplasmin gene mutations linked to aceruloplasminemia.
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Neuromolecular Med. 2006
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Acta Neurochir Suppl. 2006
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Increased urinary excretions of immunoglobulin g, ceruloplasmin, and transferrin predict development of microalbuminuria in patients with type 2 diabetes.
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Diabetes Care. 2006
PubMed ID: 16373913
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Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
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J Proteome Res. 2005
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Unexpected role of ceruloplasmin in intestinal iron absorption.
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Cell Metab. 2005
PubMed ID: 16271531
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Functional relevance of ceruloplasmin mutations in Parkinson's disease.
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FASEB J. 2005
PubMed ID: 16150804
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Science. 2005
PubMed ID: 16141073
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The transcriptional landscape of the mammalian genome.
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Science. 2005
PubMed ID: 16141072
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Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, Mukhopadhyay CK, Eckhardt K, Tröger J, Barth S, Camenisch G, Wenger RH
Blood. 2005
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The revelation of expressing region in the processed ceruloplasmin gene in human genome by biocomputational and biochemical methods.
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Biophys Chem. 2005
PubMed ID: 15752613
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The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.
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J Biol Chem. 2005
PubMed ID: 15634671
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Ceruloplasmin - acute-phase reactant or endogenous antioxidant? The case of cardiovascular disease.
Giurgea N, Constantinescu MI, Stanciu R, Suciu S, Muresan A
Med Sci Monit. 2005
PubMed ID: 15668644
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Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
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Phenotype and allele frequencies of some serum protein polymorphisms in populations of the Balkans.
Scheil HG, Schmidt HD, Efremovska L, Mikerezi I, Huckenbeck W
Anthropol Anz. 2004
PubMed ID: 15648851
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Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease.
Hochstrasser H, Bauer P, Walter U, Behnke S, Spiegel J, Csoti I, Zeiler B, Bornemann A, Pahnke J, Becker G, Riess O, Berg D
Neurology. 2004
PubMed ID: 15557511
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Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice.
Cherukuri S, Tripoulas NA, Nurko S, Fox PL
Blood Cells Mol Dis. 2004
PubMed ID: 15528156
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Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation.
Sampath P, Mazumder B, Seshadri V, Gerber CA, Chavatte L, Kinter M, Ting SM, Dignam JD, Kim S, Driscoll DM, Fox PL
Cell. 2004
PubMed ID: 15479637
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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Genome Res. 2004
PubMed ID: 15489334
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Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.
Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15365174
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Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina.
Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL
Mol Vis. 2004
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A proteomic analysis of human bile.
Kristiansen TZ, Bunkenborg J, Gronborg M, Molina H, Thuluvath PJ, Argani P, Goggins MG, Maitra A, Pandey A
Mol Cell Proteomics. 2004
PubMed ID: 15084671
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A fungal multicopper oxidase restores iron homeostasis in aceruloplasminemia.
Harris ZL, Davis-Kaplan SR, Gitlin JD, Kaplan J
Blood. 2004
PubMed ID: 14739215
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Interleukin-1beta up-regulates iron efflux in rat C6 glioma cells through modulation of ceruloplasmin and ferroportin-1 synthesis.
di Patti MC, Persichini T, Mazzone V, Polticelli F, Colasanti M, Musci G
Neurosci Lett. 2004
PubMed ID: 15172111
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Parallel increase in urinary excretion rates of immunoglobulin G, ceruloplasmin, transferrin, and orosomucoid in normoalbuminuric type 2 diabetic patients.
Narita T, Sasaki H, Hosoba M, Miura T, Yoshioka N, Morii T, Shimotomai T, Koshimura J, Fujita H, Kakei M, Ito S
Diabetes Care. 2004
PubMed ID: 15111541
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The relationship between haptoglobin polymorphism and serum ceruloplasmin ferroxidase activity.
Janaydeh M, Hamad M, Awadallah S
Clin Exp Med. 2004
PubMed ID: 15103512
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Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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Nature. 2004
PubMed ID: 15057822
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The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, Veenstra TD, Adkins JN, Pounds JG, Fagan R, Lobley A
Mol Cell Proteomics. 2004
PubMed ID: 14718574
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Involvement of glycosylphosphatidylinositol-linked ceruloplasmin in the copper/zinc-nitric oxide-dependent degradation of glypican-1 heparan sulfate in rat C6 glioma cells.
Mani K, Cheng F, Havsmark B, David S, Fransson LA
J Biol Chem. 2004
PubMed ID: 14707133
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Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR
Proteomics. 2004
PubMed ID: 14760718
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
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Nat Genet. 2004
PubMed ID: 14702039
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Sarkar J, Seshadri V, Tripoulas NA, Ketterer ME, Fox PL
J Biol Chem. 2003
PubMed ID: 12952974
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Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system.
Jeong SY, David S
J Biol Chem. 2003
PubMed ID: 12743117
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Increased expression of ceruloplasmin in the retina following photic injury.
Chen L, Dentchev T, Wong R, Hahn P, Wen R, Bennett J, Dunaief JL
Mol Vis. 2003
PubMed ID: 12724641
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Expression of a membrane-bound form of the ferroxidase ceruloplasmin by leptomeningeal cells.
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Glia. 2003
PubMed ID: 12555201
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Translational control by the 3'-UTR: the ends specify the means.
Mazumder B, Seshadri V, Fox PL
Trends Biochem Sci. 2003
PubMed ID: 12575997
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The blue copper ceruloplasmin induces aggregation of newly differentiated neurons: a potential modulator of nervous system organization.
Maltais D, Desroches D, Aouffen M, Mateescu MA, Wang R, Paquin J
Neuroscience. 2003
PubMed ID: 12946701
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Copper and ceruloplasmin status in serum of prostate and colon cancer patients.
Nayak SB, Bhat VR, Upadhyay D, Udupa SL
Indian J Physiol Pharmacol. 2003
PubMed ID: 12708132
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
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Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice.
Yamamoto K, Yoshida K, Miyagoe Y, Ishikawa A, Hanaoka K, Nomoto S, Kaneko K, Ikeda S, Takeda S
Biochim Biophys Acta. 2002
PubMed ID: 12393173
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
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Mechanisms of copper incorporation into human ceruloplasmin.
Hellman NE, Kono S, Mancini GM, Hoogeboom AJ, De Jong GJ, Gitlin JD
J Biol Chem. 2002
PubMed ID: 12351628
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A key structural role for active site type 3 copper ions in human ceruloplasmin.
Vachette P, Dainese E, Vasyliev VB, Di Muro P, Beltramini M, Svergun DI, De Filippis V, Salvato B
J Biol Chem. 2002
PubMed ID: 12177070
-
Dual role of insulin in transcriptional regulation of the acute phase reactant ceruloplasmin.
Seshadri V, Fox PL, Mukhopadhyay CK
J Biol Chem. 2002
PubMed ID: 12029093
-
Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.
Patel BN, Dunn RJ, Jeong SY, Zhu Q, Julien JP, David S
J Neurosci. 2002
PubMed ID: 12151537
-
Ceruloplasmin carries the anionic glycan oligo/poly alpha2,8 deaminoneuraminic acid.
Ziak M, Meier M, Novak-Hofer I, Roth J
Biochem Biophys Res Commun. 2002
PubMed ID: 12099680
-
Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification.
Kang JH, Kim KS, Choi SY, Kwon HY, Won MH, Kang TC
Mol Cells. 2002
PubMed ID: 12132593
-
Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.
Wistow G, Bernstein SL, Wyatt MK, Fariss RN, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K
Mol Vis. 2002
PubMed ID: 12107410
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A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.
Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD
Science. 2002
PubMed ID: 12040188
-
Dietary iron status has little effect on expression of ceruloplasmin but alters that of ferritin in rats.
Tran T, Ashraf M, Jones L, Westbrook T, Hazegh-Azam M, Linder MC
J Nutr. 2002
PubMed ID: 11880554
-
Levels of antioxidant proteins and soluble intercellular adhesion molecule-1 in serum of patients with rheumatoid arthritis.
Cogalgil S, Taysi S
Ann Clin Lab Sci. 2002
PubMed ID: 12175089
-
Ceruloplasmin metabolism and function.
Hellman NE, Gitlin JD
Annu Rev Nutr. 2002
PubMed ID: 12055353
-
Studies of the ceruloplasmin-lactoferrin complex.
Pulina MO, Zakharova ET, Sokolov AV, Shavlovski MM, Bass MG, Solovyov KV, Kokryakov VN, Vasilyev VB
Biochem Cell Biol. 2002
PubMed ID: 11908641
-
Molecular characterization of human and bovine ceruloplasmin using MALDI-TOF mass spectrometry.
Boivin S, Aouffen M, Fournier A, Mateescu MA
Biochem Biophys Res Commun. 2001
PubMed ID: 11689010
-
The gene mutated in cocoa mice, carrying a defect of organelle biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3 gene.
Suzuki T, Li W, Zhang Q, Novak EK, Sviderskaya EV, Wilson A, Bennett DC, Roe BA, Swank RT, Spritz RA
Genomics. 2001
PubMed ID: 11707070
-
Ceruloplasmin promotes iron uptake rather than release in BT325 cells.
Qian ZM, Tsoi YK, Ke Y, Wong MS
Exp Brain Res. 2001
PubMed ID: 11681312
-
Copper transport and metabolism are normal in aceruloplasminemic mice.
Meyer LA, Durley AP, Prohaska JR, Harris ZL
J Biol Chem. 2001
PubMed ID: 11461924
-
A study of genes that may modulate the expression of hereditary hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin.
Lee PL, Gelbart T, West C, Halloran C, Felitti V, Beutler E
Blood Cells Mol Dis. 2001
PubMed ID: 11783942
-
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
-
Improved radiation hybrid map of rat chromosome 2: colocalization of the genes encoding corticotropin-releasing hormone and IL6-receptor with quantitative trait loci regulating the inflammatory response.
Laes JF, Ravoet M, Quan X, Van Vooren P, Szpirer J, Szpirer C
Cytogenet Cell Genet. 2001
PubMed ID: 11306811
-
The effect of ceruloplasmin on iron release from placental (BeWo) cells; evidence for an endogenous Cu oxidase.
Danzeisen R, Ponnambalam S, Lea RG, Page K, Gambling L, McArdle HJ
Placenta. 2000
PubMed ID: 11095930
-
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
-
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
-
[Identification of a fragment of ceruloplasmin, interacting with copper-transporting Menkes ATPase]
Tsymbalenko NV, Platonova NA, Puchkova LV, Mokshina SV, Sasina LK, Skvortsova NN, Mishchenko BS, Egorov TsA, Gaĭtskoki VS
Bioorg Khim. 2000
PubMed ID: 11040994
-
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Ko MS, Kitchen JR, Wang X, Threat TA, Wang X, Hasegawa A, Sun T, Grahovac MJ, Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S, Paonessa PD, Sauls AD, DePalma GE, Sharara R, Rowe LB, Eppig J, Morrell C, Doi H
Development. 2000
PubMed ID: 10725249
-
Interaction of lactoferrin with ceruloplasmin.
Zakharova ET, Shavlovski MM, Bass MG, Gridasova AA, Pulina MO, De Filippis V, Beltramini M, Di Muro P, Salvato B, Fontana A, Vasilyev VB, Gaitskhoki VS
Arch Biochem Biophys. 2000
PubMed ID: 10666301
-
Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain.
Patel BN, Dunn RJ, David S
J Biol Chem. 2000
PubMed ID: 10660599
-
Delayed translational silencing of ceruloplasmin transcript in gamma interferon-activated U937 monocytic cells: role of the 3' untranslated region.
Mazumder B, Fox PL
Mol Cell Biol. 1999
PubMed ID: 10490627
-
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux.
Harris ZL, Durley AP, Man TK, Gitlin JD
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10485908
-
Dexamethasone induced alterations in the levels of proteases involved in blood pressure homeostasis and blood coagulation in rats.
Rajashree S, Puvanakrishnan R
Mol Cell Biochem. 1999
PubMed ID: 10485340
-
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
-
Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin.
Salzer JL, Lovejoy L, Linder MC, Rosen C
J Neurosci Res. 1998
PubMed ID: 9788274
-
Comparative gene mapping: a fine-scale survey of chromosome rearrangements between ruminants and humans.
Schibler L, Vaiman D, Oustry A, Giraud-Delville C, Cribiu EP
Genome Res. 1998
PubMed ID: 9750190
-
Aceruloplasminemia.
Gitlin JD
Pediatr Res. 1998
PubMed ID: 9727700
-
The bilirubin-binding motif of bilitranslocase and its relation to conserved motifs in ancient biliproteins.
Battiston L, Passamonti S, Macagno A, Sottocasa GL
Biochem Biophys Res Commun. 1998
PubMed ID: 9647754
-
Intracellular distribution of the Wilson's disease gene product (ATPase7B) after in vitro and in vivo exogenous expression in hepatocytes from the LEC rat, an animal model of Wilson's disease.
Nagano K, Nakamura K, Urakami KI, Umeyama K, Uchiyama H, Koiwai K, Hattori S, Yamamoto T, Matsuda I, Endo F
Hepatology. 1998
PubMed ID: 9500710
-
Role of ceruloplasmin in cellular iron uptake.
Mukhopadhyay CK, Attieh ZK, Fox PL
Science. 1998
PubMed ID: 9445478
-
Comparative analysis of the molecular heterogeneity of ceruloplasmin from human blood and breast milk.
Puchkova LV, Zakharova ET, Aleinikova TD, Mokshina SV, Tsymbalenko NV, Sasina LK, Shirmanova MR, Rogacheva NP, Gaitskhoki VS
Biochemistry (Mosc). 1997
PubMed ID: 9360306
-
Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?
Segelmark M, Persson B, Hellmark T, Wieslander J
Clin Exp Immunol. 1997
PubMed ID: 9097926
-
Expression of the ceruloplasmin gene in the human retina and brain: implications for a pathogenic model in aceruloplasminemia.
Klomp LW, Gitlin JD
Hum Mol Genet. 1996
PubMed ID: 8968753
-
Ceruloplasmin gene expression in the murine central nervous system.
Klomp LW, Farhangrazi ZS, Dugan LL, Gitlin JD
J Clin Invest. 1996
PubMed ID: 8690795
-
Expression of ceruloplasmin gene in human and rat lymphocytes.
Pan Y, Katula K, Failla ML
Biochim Biophys Acta. 1996
PubMed ID: 8679709
-
Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.
Harris ZL, Takahashi Y, Miyajima H, Serizawa M, MacGillivray RT, Gitlin JD
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7708681
-
Fine structure of the human ceruloplasmin gene.
Daimon M, Yamatani K, Igarashi M, Fukase N, Kawanami T, Kato T, Tominaga M, Sasaki H
Biochem Biophys Res Commun. 1995
PubMed ID: 7702601
-
Four human chromosome 3q and four human chromosome 21 loci map onto sheep chromosome 1q.
Broad TE, Burkin DJ, Cambridge LM, Lewis PE, Maher DW, Ansari HA, Pearce PD, Jones C
Mamm Genome. 1995
PubMed ID: 7749229
-
A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans.
Yoshida K, Furihata K, Takeda S, Nakamura A, Yamamoto K, Morita H, Hiyamuta S, Ikeda S, Shimizu N, Yanagisawa N
Nat Genet. 1995
PubMed ID: 7539672
-
Caeruloplasmin biosynthesis by the human uterus.
Schilsky ML, Stockert RJ, Pollard JW
Biochem J. 1992
PubMed ID: 1463466
-
Structural and functional analysis of the 5'-flanking region of the rat ceruloplasmin gene.
Fleming RE, Gitlin JD
J Biol Chem. 1992
PubMed ID: 1730611
-
Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.
Threadgill DS, Womack JE
Genomics. 1991
PubMed ID: 1783381
-
Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing.
Yang FM, Friedrichs WE, Cupples RL, Bonifacio MJ, Sanford JA, Horton WA, Bowman BH
J Biol Chem. 1990
PubMed ID: 2355023
-
Primary structure of rat ceruloplasmin and analysis of tissue-specific gene expression during development.
Fleming RE, Gitlin JD
J Biol Chem. 1990
PubMed ID: 2332446
-
Detection of multiple forms of human ceruloplasmin. A novel Mr 200,000 form.
Sato M, Schilsky ML, Stockert RJ, Morell AG, Sternlieb I
J Biol Chem. 1990
PubMed ID: 2154449
-
Characterization of an interaction between protein C and ceruloplasmin.
Walker FJ, Fay PJ
J Biol Chem. 1990
PubMed ID: 2105310
-
Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively.
Royle NJ, Irwin DM, Koschinsky ML, MacGillivray RT, Hamerton JL
Somat Cell Mol Genet. 1987
PubMed ID: 3474786
-
Rat ceruloplasmin. Molecular cloning and gene expression in liver, choroid plexus, yolk sac, placenta, and testis.
Aldred AR, Grimes A, Schreiber G, Mercer JF
J Biol Chem. 1987
PubMed ID: 3818625
-
Chromosomal localization of ceruloplasmin and transferrin genes in laboratory rats, mice and in man by hybridization with specific DNA probes.
Baranov VS, Schwartzman AL, Gorbunova VN, Gaitskhoki VS, Rubtsov NB, Timchenko NA, Neifakh SA
Chromosoma. 1987
PubMed ID: 3436225
-
Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence.
Mercer JF, Grimes A
FEBS Lett. 1986
PubMed ID: 3755405
-
Complete cDNA sequence of human preceruloplasmin.
Koschinsky ML, Funk WD, van Oost BA, MacGillivray RT
Proc Natl Acad Sci U S A. 1986
PubMed ID: 2873574
-
Characterization, mapping, and expression of the human ceruloplasmin gene.
Yang F, Naylor SL, Lum JB, Cutshaw S, McCombs JL, Naberhaus KH, McGill JR, Adrian GS, Moore CM, Barnett DR
Proc Natl Acad Sci U S A. 1986
PubMed ID: 3486416
-
[Mapping of the ceruloplasmin gene on human and laboratory mouse chromosomes by direct in situ hybridization]
Baranov VS, Shvartsman AL, Gorbunova VN, Gaĭtskhoki VS, Neĭfakh SA
Genetika. 1985
PubMed ID: 3886485
-
Origins of biliary copper.
Kressner MS, Stockert RJ, Morell AG, Sternlieb I
Hepatology. 1984
PubMed ID: 6479854
-
Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule.
Takahashi N, Ortel TL, Putnam FW
Proc Natl Acad Sci U S A. 1984
PubMed ID: 6582496
-
Internal triplication in the structure of human ceruloplasmin.
Takahashi N, Bauman RA, Ortel TL, Dwulet FE, Wang CC, Putnam FW
Proc Natl Acad Sci U S A. 1983
PubMed ID: 6571985
-
Subcellular localization in normal and vitamin A-deficient rat liver of vitamin A serum transport proteins, albumin, ceruloplasmin and class I major histocompatibility antigens.
Rask L, Valtersson C, Anundi H, Kvist S, Eriksson U, Dallner G, Peterson PA
Exp Cell Res. 1983
PubMed ID: 6337857
-
Complete amino acid sequence of a 50,000-dalton fragment of human ceruloplasmin.
Dwulet FE, Putnam FW
Proc Natl Acad Sci U S A. 1981
PubMed ID: 6940148
-
Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. II. Amino acid sequence of the tryptic peptides.
Kingston IB, Kingston BL, Putnam FW
J Biol Chem. 1980
PubMed ID: 6987230
-
Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. I. Amino acid sequence of the cyanogen bromide peptides.
Kingston IB, Kingston BL, Putnam FW
J Biol Chem. 1980
PubMed ID: 6987229
-
Interaction of synthetic human big gastrin with blood proteins of man and animals.
Polosatov MV, Klimov PK, Masevich CG, Samartsev MA, Wünsch E
Acta Hepatogastroenterol (Stuttg). 1979
PubMed ID: 463490
-
Chemical evidence that proteolytic cleavage causes the heterogeneity present in human ceruloplasmin preparations.
Kingston IB, Kingston BL, Putnam FW
Proc Natl Acad Sci U S A. 1977
PubMed ID: 146197
-
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