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CCR5

Gene Description:   chemokine (C-C motif) receptor 5 Synonyms:   CCR5, CD195, Cmkbr5, CKR5, FLJ78003, CCCKR5, CC-CKR-5, CMKBR5, IDDM22, Ckr5, AM4-7, CKR-5, Ccr5 Orthologs:   Human CCR5 (protein-coding), Mouse Ccr5 (protein-coding), Rat Ccr5 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, KEGG Human-Rat: HomoloGene, MGD, RGD, KEGG Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL, KEGG Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1 Rat: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
3p21.31	Human	chr3:45980673..46654132	0.67	77	rs333 rs11711054

Other Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Human 3p21.31 Orthologous Region	Mouse	chr9:123713859..124045161	0.33	9
Human 3p21.31 Orthologous Region	Rat	chr8:128563968..128916583	0.35	8

(Human) GRCh37 - chr3:46411633..46417697 (66 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr9:124036282..124062438 (26.16 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr8:128907157..128912272 (5.12 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for CCR5: The CCR5 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs CCR5   CREB3   IntAct  empirical  15001559  CCR5   ARL6IP5   HPRD, MINT  empirical  15757671  CCR5   PRAF2   HPRD, MINT  empirical  15757671  CCR5   CCR5   HPRD  empirical  12065593  12176010  CCR5   ADRBK1   HPRD  empirical  10085131  CCR5   ADRBK2   HPRD  empirical  10085131  CCR5   AFP   HPRD, BioGRID  empirical  12176010  CCR5   DNM2   HPRD  empirical  10477567  CCR5   PTK2B   HPRD  empirical  9446638  CCR5   GNAI1   HPRD  empirical  15251452  CCR5   GNAI2   HPRD  empirical  15251452  CCR5   GNAI3   HPRD  empirical  15251452  CCR5   GNAO1   HPRD  empirical  15251452  CCR5   GNAQ   HPRD  empirical  15251452  CCR5   JAK1   HPRD  empirical  10037796  CCR5   JAK2   HPRD, BioGRID  empirical  11591716  11278738  CCR5   LCK   HPRD  empirical  11591716  CCR5   ARRB1   HPRD, BioGRID  empirical  12065593  CCR5   CCL3L3   HPRD  empirical  11734558  10364178  CCR5   MYH9   IntAct  empirical  12421915  CCR5   ORM1   HPRD  empirical  11336643  CCR5   PIK3R2   BioGRID  empirical  11350939  CCR5   PSMA5   HPRD  empirical  11877445  CCR5   PTK2   HPRD, BioGRID  empirical  10384144  CCR5   CCL2   HPRD  empirical  10477718  CCR5   CCL3   HPRD, BioGRID  empirical  11700073  10477718  CCR5   CCL3L1   HPRD  empirical  11734558  11449371  CCR5   CCL4   HPRD  empirical  12427015  8663314  CCR5   CCL5   HPRD, BioGRID, Reactome  empirical  9289016  8663314  11116158  14637022  10477718  11449371  8639485  7642634  7622448  CCR5   CCL7   HPRD  empirical  10477718  CCR5   CCL8   HPRD  empirical  9468473  10477718  CCR5   CCL11   HPRD  empirical  11264152  10477718  CCR5   CCL13   HPRD  empirical  10477718  CCR5   CCL14   HPRD  empirical  11085751  CCR5   CCL16   HPRD  empirical  11470772  CCR5   STAT1   HPRD  empirical  14674010  CCR5   STAT3   HPRD, BioGRID  empirical  14674010  11350939  CCR5   STAT5A   HPRD  empirical  10037796  CCR5   STAT5B   BioGRID  empirical  11350939  CCR5   TXK   HPRD  empirical  11859127  CCR5   CXCR4   HPRD, IntAct  empirical  12429730  15660419  CCR5   CD4   HPRD, IntAct, BioGRID  empirical  10816381  15660419

View all

KEGG Network: 4   Chemokine signaling pathway Human - 4062 Mouse - 4062 Rat - 4062 Cytokine-cytokine receptor interaction Human - 4060 Mouse - 4060 Rat - 4060 Endocytosis Human - 4144 Mouse - 4144 Rat - 4144 Toxoplasmosis Human - 5145 Mouse - 5145 Rat - 5145

Biocarta: 5   HIV Induced T Cell Apoptosis Human Mouse IL12 and Stat4 Dependent Signaling Pathway in Th1 Development Human Mouse NO2-dependent IL 12 Pathway in NK cells Human Mouse Pertussis toxin-insensitive CCR5 Signaling in Macrophage Human Mouse Selective expression of chemokine receptors during T-cell polarization Human Mouse

Reactome: 8   Chemokine receptors bind chemokines REACT_15344 Class A/1 (Rhodopsin-like receptors) REACT_14828 Early Phase of HIV Life Cycle REACT_6266 G alpha (i) signalling events REACT_19231 GPCR downstream signaling REACT_19184 GPCR ligand binding REACT_21340 Peptide ligand-binding receptors REACT_14819 Signaling by GPCR REACT_14797

NCI-Nature Pathway Interaction Database: 1   IL12-mediated signaling events

Gene Ontology: 28   Dendritic cell chemotaxis GO:0002407 Actin binding GO:0003779 Phosphatidylinositol phospholipase C activity GO:0004435 Signal transducer activity GO:0004871 Receptor activity GO:0004872 G-protein coupled receptor activity GO:0004930 Chemokine receptor activity GO:0004950 Protein binding GO:0005515 Cytoplasm GO:0005737 Endosome GO:0005768 Plasma membrane GO:0005886 Integral to plasma membrane GO:0005887 Chemotaxis GO:0006935 Inflammatory response GO:0006954 Immune response GO:0006955 Cellular defense response GO:0006968 Cell surface receptor linked signaling pathway GO:0007166 G-protein coupled receptor protein signaling pathway GO:0007186 Elevation of cytosolic calcium ion concentration GO:0007204 Cell-cell signaling GO:0007267 External side of plasma membrane GO:0009897 Cell surface GO:0009986 Coreceptor activity GO:0015026 Viral reproduction GO:0016032 C-C chemokine receptor activity GO:0016493 Initiation of viral infection GO:0019059 Entry into host cell GO:0030260 Interspecies interaction between organisms GO:0044419

	KEGG Network: 4 Chemokine signaling pathway Human - 4062 Mouse - 4062 Rat - 4062 Cytokine-cytokine receptor interaction Human - 4060 Mouse - 4060 Rat - 4060 Endocytosis Human - 4144 Mouse - 4144 Rat - 4144 Toxoplasmosis Human - 5145 Mouse - 5145 Rat - 5145
	Biocarta: 5 HIV Induced T Cell Apoptosis Human Mouse IL12 and Stat4 Dependent Signaling Pathway in Th1 Development Human Mouse NO2-dependent IL 12 Pathway in NK cells Human Mouse Pertussis toxin-insensitive CCR5 Signaling in Macrophage Human Mouse Selective expression of chemokine receptors during T-cell polarization Human Mouse
	Reactome: 8 Chemokine receptors bind chemokines REACT_15344 Class A/1 (Rhodopsin-like receptors) REACT_14828 Early Phase of HIV Life Cycle REACT_6266 G alpha (i) signalling events REACT_19231 GPCR downstream signaling REACT_19184 GPCR ligand binding REACT_21340 Peptide ligand-binding receptors REACT_14819 Signaling by GPCR REACT_14797
	NCI-Nature Pathway Interaction Database: 1 IL12-mediated signaling events
	Gene Ontology: 28 Dendritic cell chemotaxis GO:0002407 Actin binding GO:0003779 Phosphatidylinositol phospholipase C activity GO:0004435 Signal transducer activity GO:0004871 Receptor activity GO:0004872 G-protein coupled receptor activity GO:0004930 Chemokine receptor activity GO:0004950 Protein binding GO:0005515 Cytoplasm GO:0005737 Endosome GO:0005768 Plasma membrane GO:0005886 Integral to plasma membrane GO:0005887 Chemotaxis GO:0006935 Inflammatory response GO:0006954 Immune response GO:0006955 Cellular defense response GO:0006968 Cell surface receptor linked signaling pathway GO:0007166 G-protein coupled receptor protein signaling pathway GO:0007186 Elevation of cytosolic calcium ion concentration GO:0007204 Cell-cell signaling GO:0007267 External side of plasma membrane GO:0009897 Cell surface GO:0009986 Coreceptor activity GO:0015026 Viral reproduction GO:0016032 C-C chemokine receptor activity GO:0016493 Initiation of viral infection GO:0019059 Entry into host cell GO:0030260 Interspecies interaction between organisms GO:0044419

Type 1 Diabetes Publications: 20

• Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy.
  Pettigrew KA, McKnight AJ, Patterson CC, Kilner J, Sadlier DM, Maxwell AP
  J Hum Genet. 2010
  PubMed ID: 20203694
   
  
• CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse.
  Solomon M, Balasa B, Sarvetnick N
  Autoimmunity. 2010
  PubMed ID: 19824873
   
  
• Chemokine receptor 532 mutation reduces the risk of acute rejection in liver transplantation.
  Heidenhain C, Puhl G, Moench C, Lautem A, Neuhaus P
  Ann Transplant. 2009
  PubMed ID: 19644158
   
  
• Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.
  Zhang N, Schröppel B, Lal G, Jakubzick C, Mao X, Chen D, Yin N, Jessberger R, Ochando JC, Ding Y, Bromberg JS
  Immunity. 2009
  PubMed ID: 19303390
   
  
• Shared and distinct genetic variants in type 1 diabetes and celiac disease.
  Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA
  N Engl J Med. 2008
  PubMed ID: 19073967
   
  
• Lack of CCR5 on dendritic cells promotes a proinflammatory environment in submandibular glands of the NOD mouse.
  Wildenberg ME, van Helden-Meeuwsen CG, van de Merwe JP, Moreno C, Drexhage HA, Versnel MA
  J Leukoc Biol. 2008
  PubMed ID: 18285404
   
  
• Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis.
  McKinney C, Merriman ME, Chapman PT, Gow PJ, Harrison AA, Highton J, Jones PB, McLean L, O'Donnell JL, Pokorny V, Spellerberg M, Stamp LK, Willis J, Steer S, Merriman TR
  Ann Rheum Dis. 2008
  PubMed ID: 17604289
   
  
• Blocking the CC chemokine receptor 5 pathway by antisense peptide nucleic acid prolongs islet allograft survival.
  Yang L, Liu YF, Wu G, Zhang JL, Wang FS, Fu DZ, Zhao GH, Li TM
  Transplant Proc. 2007
  PubMed ID: 17275502
   
  
• Genetic variants of RANTES are associated with serum RANTES level and protection for type 1 diabetes.
  Zhernakova A, Alizadeh BZ, Eerligh P, Hanifi-Moghaddam P, Schloot NC, Diosdado B, Wijmenga C, Roep BO, Koeleman BP
  Genes Immun. 2006
  PubMed ID: 16855620
   
  
• CCR5 in T cell-mediated liver diseases: what's going on?
  Ajuebor MN, Carey JA, Swain MG
  J Immunol. 2006
  PubMed ID: 16887960
   
  
• Where CD4+CD25+ T reg cells impinge on autoimmune diabetes.
  Chen Z, Herman AE, Matos M, Mathis D, Benoist C
  J Exp Med. 2005
  PubMed ID: 16301745
   
  
• Risk of diabetic nephropathy in type 1 diabetes is associated with functional polymorphisms in RANTES receptor gene (CCR5): a sex-specific effect.
  Mlynarski WM, Placha GP, Wolkow PP, Bochenski JP, Warram JH, Krolewski AS
  Diabetes. 2005
  PubMed ID: 16249462
   
  
• Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DR-BB rats.
  Mendez II, Chung YH, Jun HS, Yoon JW
  J Immunol. 2004
  PubMed ID: 15240727
   
  
• Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.
  Schröppel B, Zhang N, Chen P, Zang W, Chen D, Hudkins KL, Kuziel WA, Sung R, Bromberg JS, Murphy B
  J Am Soc Nephrol. 2004
  PubMed ID: 15213273
   
  
• Polymorphisms of chemokine and chemokine receptor genes in Type 1 diabetes mellitus and its complications.
  Yang B, Houlberg K, Millward A, Demaine A
  Cytokine. 2004
  PubMed ID: 15135805
   
  
• CC-chemokine receptor CCR5-del32 mutation as a modifying pathogenetic factor in type I diabetes.
  Kalev I, Oselin K, Pärlist P, Zilmer M, Rajasalu T, Podar T, Mikelsaar AV
  J Diabetes Complications. 2003
  PubMed ID: 14583186
   
  
• CCR5 genotyping in an Australian and New Zealand type 1 diabetes cohort.
  Buhler MM, Craig M, Donaghue KC, Badhwar P, Willis J, Manolios N, Tait BD, Silink M, Bennetts BH, Stewart GJ
  Autoimmunity. 2002
  PubMed ID: 12688247
   
  
• The role of CC chemokine receptor 5 (CCR5) in islet allograft rejection.
  Abdi R, Smith RN, Makhlouf L, Najafian N, Luster AD, Auchincloss H, Sayegh MH
  Diabetes. 2002
  PubMed ID: 12145162
   
  
• Reduced expression of Th1-associated chemokine receptors on peripheral blood lymphocytes at diagnosis of type 1 diabetes.
  Lohmann T, Laue S, Nietzschmann U, Kapellen TM, Lehmann I, Schroeder S, Paschke R, Kiess W
  Diabetes. 2002
  PubMed ID: 12145160
   
  
• A common stromal cell-derived factor-1 chemokine gene variant is associated with the early onset of type 1 diabetes.
  Dubois-Laforgue D, Hendel H, Caillat-Zucman S, Zagury JF, Winkler C, Boitard C, Timsit J
  Diabetes. 2001
  PubMed ID: 11334429
   
  

Publications: 1102

• Protein kinase Czeta mediates micro-opioid receptor-induced cross-desensitization of chemokine receptor CCR5.
  Song C, Rahim RT, Davey PC, Bednar F, Bardi G, Zhang L, Zhang N, Oppenheim JJ, Rogers TJ
  J Biol Chem. 2011
  PubMed ID: 21454526
   
  
• CCR5 chemokine receptor polymorphism in patients with HIV-1 from Western India.
  Shankarkumar A, Shankarkumar U, Ghosh K
  J Acquir Immune Defic Syndr. 2011
  PubMed ID: 21709449
   
  
• Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population.
  Mamtani M, Mummidi S, Ramsuran V, Pham MH, Maldonado R, Begum K, Valera MS, Sanchez R, Castiblanco J, Kulkarni H, Ndung'u T, He W, Anaya JM, Ahuja SK
  J Infect Dis. 2011
  PubMed ID: 21592988
   
  
• Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus.
  Sezgin E, van Natta ML, Ahuja A, Lyon A, Srivastava S, Troyer JL, O'Brien SJ, Jabs DA, Studies of the Ocular Complications of AIDS Research Group
  Am J Ophthalmol. 2011
  PubMed ID: 21396623
   
  
• Ccr5 deficiency regulates the proliferation and trafficking of natural killer cells under physiological conditions.
  Weiss ID, Shoham H, Wald O, Wald H, Beider K, Abraham M, Barashi N, Galun E, Nagler A, Peled A
  Cytokine. 2011
  PubMed ID: 21376626
   
  
• An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection.
  Kroetz DN, Deepe GS
  J Immunol. 2011
  PubMed ID: 21478401
   
  
• Role of the CCR5/Δ32CCR5 polymorphism in biopsy-proven giant cell arteritis.
  Carmona FD, Rodríguez-Rodríguez L, Castañeda S, Miranda-Filloy JA, Morado IC, Narváez J, Marí-Alfonso B, Unzurrunzaga A, Ríos-Fernández R, Blanco R, de Miguel E, Martín J, González-Gay MA
  Hum Immunol. 2011
  PubMed ID: 21354457
   
  
• CCR5 mediates pro-osteoclastic and osteoclastogenic leukocyte chemoattraction.
  Ferreira SB, Repeke CE, Raimundo FM, Nunes IS, Avila-Campos MJ, Ferreira BR, Santana da Silva J, Campanelli AP, Garlet GP
  J Dent Res. 2011
  PubMed ID: 21245464
   
  
• CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infection.
  Gouwy M, Struyf S, Berghmans N, Vanormelingen C, Schols D, Van Damme J
  Eur J Immunol. 2011
  PubMed ID: 21381021
   
  
• CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction.
  Zamilpa R, Kanakia R, Cigarroa J, Dai Q, Escobar GP, Martinez H, Jimenez F, Ahuja SS, Lindsey ML
  Am J Physiol Heart Circ Physiol. 2011
  PubMed ID: 21297029
   
  
• Experimental infection with Schistosoma mansoni in CCR5-deficient mice is associated with increased disease severity, as CCR5 plays a role in controlling granulomatous inflammation.
  Souza AL, Souza PR, Pereira CA, Fernandes A, Guabiraba R, Russo RC, Vieira LQ, Corrêa A, Teixeira MM, Negrão-Corrêa D
  Infect Immun. 2011
  PubMed ID: 21263020
   
  
• Using the distribution of the CCR5-Δ32 allele in third-generation Maltese citizens to disprove the Black Death hypothesis.
  Baron B, Schembri-Wismayer P
  Int J Immunogenet. 2011
  PubMed ID: 21156032
   
  
• Chemokine (CCR) and fractalkine (CX3CR) receptors and end stage renal disease.
  Borkar M, Tripathi G, Sharma RK, Sankhwar SN, Agrawal S
  Inflamm Res. 2011
  PubMed ID: 21132346
   
  
• Tests and estimates (transmission disequilibrium test) for allelic association of CCR5delta32 with asthma in high-risk families.
  Al-Abdulhadi SA, Al-Rabia MW
  J Pak Med Assoc. 2011
  PubMed ID: 21465943
   
  
• Polymorphisms in chemokine and receptor genes and gastric cancer risk and survival in a high risk Polish population.
  Gawron AJ, Fought AJ, Lissowska J, Ye W, Zhang X, Chow WH, Beane Freeman LE, Hou L
  Scand J Gastroenterol. 2011
  PubMed ID: 21091093
   
  
• CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa.
  Olive AJ, Gondek DC, Starnbach MN
  Mucosal Immunol. 2011
  PubMed ID: 20844481
   
  
• New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection.
  Garcia-Perez J, Rueda P, Staropoli I, Kellenberger E, Alcami J, Arenzana-Seisdedos F, Lagane B
  J Biol Chem. 2011
  PubMed ID: 21118814
   
  
• TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes.
  Fox JM, Letellier E, Oliphant CJ, Signoret N
  Blood. 2011
  PubMed ID: 21148810
   
  
• Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
  Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD
  Nat Immunol. 2011
  PubMed ID: 21217759
   
  
• Neurotrophins modulate the expression of chemokine receptors in the brain.
  Avdoshina V, Becker J, Campbell LA, Parsadanian M, Mhyre T, Tessarollo L, Mocchetti I
  J Neurovirol. 2011
  PubMed ID: 21165786
   
  
• Direct measurement of thermal stability of expressed CCR5 and stabilization by small molecule ligands.
  Knepp AM, Grunbeck A, Banerjee S, Sakmar TP, Huber T
  Biochemistry. 2011
  PubMed ID: 21155586
   
  
• Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage.
  Louboutin JP, Chekmasova A, Marusich E, Agrawal L, Strayer DS
  FASEB J. 2011
  PubMed ID: 20940264
   
  
• Interferon-γ links ultraviolet radiation to melanomagenesis in mice.
  Zaidi MR, Davis S, Noonan FP, Graff-Cherry C, Hawley TS, Walker RL, Feigenbaum L, Fuchs E, Lyakh L, Young HA, Hornyak TJ, Arnheiter H, Trinchieri G, Meltzer PS, De Fabo EC, Merlino G
  Nature. 2011
  PubMed ID: 21248750
   
  
• Concordance of CCR5 genotypes that influence cell-mediated immunity and HIV-1 disease progression rates.
  Catano G, Chykarenko ZA, Mangano A, Anaya JM, He W, Smith A, Bologna R, Sen L, Clark RA, Lloyd A, Shostakovich-Koretskaya L, Ahuja SK
  J Infect Dis. 2011
  PubMed ID: 21288827
   
  
• Chemokine receptor 5 polymorphism in myocardial infarction patients from Luxembourg.
  Rodius S, Lambert C, Devaux C, Schmit JC, Devaux Y, Wagner DR
  Bull Soc Sci Med Grand Duche Luxemb. 2011
  PubMed ID: 21634220
   
  
• Selected amino acid mutations in HIV-1 B subtype gp41 are associated with specific gp120v₃ signatures in the regulation of co-receptor usage.
  Dimonte S, Mercurio F, Svicher V, D'Arrigo R, Perno CF, Ceccherini-Silberstein F
  Retrovirology. 2011
  PubMed ID: 21569409
   
  
• Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially.
  Thielen A, Lengauer T, Swenson LC, Dong WW, McGovern RA, Lewis M, James I, Heera J, Valdez H, Harrigan PR
  Antivir Ther. 2011
  PubMed ID: 21555814
   
  
• Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.
  Malhotra R, Hu L, Song W, Brill I, Mulenga J, Allen S, Hunter E, Shrestha S, Tang J, Kaslow RA
  Retrovirology. 2011
  PubMed ID: 21429204
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• TNF-α levels are not increased in inflamed patients carrying the CCR5 deletion 32.
  Muntinghe FL, Carrero JJ, Navis G, Stenvinkel P
  Cytokine. 2011
  PubMed ID: 20932773
   
  
• CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network.
  Escola JM, Kuenzi G, Gaertner H, Foti M, Hartley O
  J Biol Chem. 2010
  PubMed ID: 21041313
   
  
• Functional CCR5 receptor protects patients with arthritis from high synovial burden of infecting Chlamydia trachomatis.
  Gérard HC, Stanich JA, Oszust CE, Whittum-Hudson JA, Carter JD, Schumacher HR, Hudson AP
  Am J Med Sci. 2010
  PubMed ID: 20811274
   
  
• Association of CCR5, TLR2, TLR4 and MBL genetic variations with genital tract infections and tubal factor infertility.
  Laisk T, Peters M, Saare M, Haller-Kikkatalo K, Karro H, Salumets A
  J Reprod Immunol. 2010
  PubMed ID: 20598754
   
  
• An additive effect of protective host genetic factors correlates with HIV-non progression status.
  Salgado M, Simón A, Sanz-Minguela B, Rallón NI, López M, Vicario JL, Benito JM, Rodés B
  J Acquir Immune Defic Syndr. 2010
  PubMed ID: 21084992
   
  
• Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer.
  Hammad MM, Kuang YQ, Yan R, Allen H, Dupré DJ
  J Biol Chem. 2010
  PubMed ID: 20801883
   
  
• Klebsiella pneumoniae-triggered DC recruit human NK cells in a CCR5-dependent manner leading to increased CCL19-responsiveness and activation of NK cells.
  Van Elssen CH, Vanderlocht J, Frings PW, Senden-Gijsbers BL, Schnijderberg MC, van Gelder M, Meek B, Libon C, Ferlazzo G, Germeraad WT, Bos GM
  Eur J Immunol. 2010
  PubMed ID: 20865789
   
  
• Lack of association of C-C chemokine receptor 5 Δ32 deletion status with rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and disease severity.
  Martens HA, Gross S, van der Steege G, Brouwer E, Berden JH, de Sevaux R, Derksen RH, Voskuyl AE, Berger SP, Navis GJ, Kallenberg CG, Bijl M
  J Rheumatol. 2010
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• Didecyldimethylammonium chloride induces pulmonary inflammation and fibrosis in mice.
  Ohnuma A, Yoshida T, Tajima H, Fukuyama T, Hayashi K, Yamaguchi S, Ohtsuka R, Sasaki J, Fukumori J, Tomita M, Kojima S, Takahashi N, Takeuchi Y, Kuwahara M, Takeda M, Kosaka T, Nakashima N, Harada T
  Exp Toxicol Pathol. 2010
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• [The expression of periphery blood leucocyte CCR3 and CCR5 in the children with Epstein-Barr virus associated infectious mononucleosis].
  Qi TX, Gao GH, Liu SH
  Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2010
  PubMed ID: 21280323
   
  
• Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.
  Keynan Y, Juno J, Meyers A, Ball TB, Kumar A, Rubinstein E, Fowke KR
  Emerg Infect Dis. 2010
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• Effect of CC chemokine ligand 5 and CC chemokine receptor 5 genes polymorphisms on the risk and clinicopathological development of oral cancer.
  Weng CJ, Chien MH, Lin CW, Chung TT, Zavras AI, Tsai CM, Chen MK, Yang SF
  Oral Oncol. 2010
  PubMed ID: 20729133
   
  
• Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
  Diabetes Care. 2010
  PubMed ID: 20628086
   
  
• Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-1alpha.
  Iida N, Nakamoto Y, Baba T, Nakagawa H, Mizukoshi E, Naito M, Mukaida N, Kaneko S
  Cancer Res. 2010
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• A fusion protein encoding the second extracellular domain of CCR5 arrests chemokine-induced cosignaling and effectively suppresses ongoing experimental autoimmune encephalomyelitis.
  Sapir Y, Vitenshtein A, Barsheshet Y, Zohar Y, Wildbaum G, Karin N
  J Immunol. 2010
  PubMed ID: 20639487
   
  
• Intrauterine growth restriction alters hippocampal expression and chromatin structure of Cyp19a1 variants.
  O'Grady SP, Caprau D, Ke XR, Contreras Y, Haley S, Ermini F, Penn A, Moyer-Mileur L, McKnight R, Lane R
  Syst Biol Reprod Med. 2010
  PubMed ID: 20662593
   
  
• Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism.
  Beckers MM, Ruven HJ, Haas FJ, Doevendans PA, ten Cate H, Prins MH, Biesma DH
  Eur J Intern Med. 2010
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• Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS.
  Sezgin E, Hendrickson SL, Jabs DA, Van Natta ML, Lewis RA, Troyer JL, O'Brien SJ, SOCA Research Group
  J Acquir Immune Defic Syndr. 2010
  PubMed ID: 20531015
   
  
• CCR5, RANTES and SDF-1 polymorphisms and mother-to-child HIV-1 transmission.
  Katz DA, John-Stewart GC, Richardson BA, Majiwa M, Mabuka JM, Lohman-Payne B, Farquhar C
  Int J Immunogenet. 2010
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• South African mutations of the CCR5 coreceptor for HIV modify interaction with chemokines and HIV Envelope protein.
  Folefoc AT, Fromme BJ, Katz AA, Flanagan CA
  J Acquir Immune Defic Syndr. 2010
  PubMed ID: 20442662
   
  
• Constrained use of CCR5 on CD4+ lymphocytes by R5X4 HIV-1: efficiency of Env-CCR5 interactions and low CCR5 expression determine a range of restricted CCR5-mediated entry.
  Loftin LM, Kienzle MF, Yi Y, Lee B, Lee FH, Gray L, Gorry PR, Collman RG
  Virology. 2010
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• APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors.
  Spector SA, Singh KK, Gupta S, Cystique LA, Jin H, Letendre S, Schrier R, Wu Z, Hong KX, Yu X, Shi C, Heaton RK, HNRC Group
  AIDS. 2010
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• Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
  Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
  Pediatr Pulmonol. 2010
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• A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
  Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, Yamazaki K, Hosono N, Myouzen K, Tsunoda T, Kamatani N, Furuichi T, Ikegawa S, Ohmura K, Mimori T, Matsuda F, Iwamoto T, Momohara S, Yamanaka H, Yamada R, Kubo M, Nakamura Y, Yamamoto K
  Nat Genet. 2010
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• Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.
  Sombekke MH, Arteta D, van de Wiel MA, Crusius JB, Tejedor D, Killestein J, Martínez A, Peña AS, Polman CH, Uitdehaag BM
  Mult Scler. 2010
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• CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.
  Nesbeth YC, Martinez DG, Toraya S, Scarlett UK, Cubillos-Ruiz JR, Rutkowski MR, Conejo-Garcia JR
  J Immunol. 2010
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• Association of the CCR5 gene with juvenile idiopathic arthritis.
  Hinks A, Martin P, Flynn E, Eyre S, Packham J, Childhood Arthritis Prospective Study (CAPS), UKRAG Consortium, BSPAR Study Group, Barton A, Worthington J, Thomson W
  Genes Immun. 2010
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• [Complex analsis of association of inflammation genes with myocardial infarction].
  Sudomoina MA, Sukhinina TS, Barsova RM, Favorov AV, Shakhnovich RM, Titov BV, Matveeva NA, Rybalkin IN, Vlasik TN, Ochs MF, Ruda MIa, Favorova OO
  Mol Biol (Mosk). 2010
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• Distribution of CCR5-{delta}32, CCR2-64I, and SDF1-3'A in Guangxi Zhuang population.
  Qijian Su, Zhidan Mai, Ning Zang, Shuzhi Wu, Xin Xiao, Hao Liang
  J Int Assoc Physicians AIDS Care (Chic Ill). 2010
  PubMed ID: 20530467
   
  
• Memory CD4+ T cells induce innate responses independently of pathogen.
  Strutt TM, McKinstry KK, Dibble JP, Winchell C, Kuang Y, Curtis JD, Huston G, Dutton RW, Swain SL
  Nat Med. 2010
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• CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells.
  Dobaczewski M, Xia Y, Bujak M, Gonzalez-Quesada C, Frangogiannis NG
  Am J Pathol. 2010
  PubMed ID: 20382703
   
  
• CCR5 dictates the equilibrium of proinflammatory IL-17+ and regulatory Foxp3+ T cells in fungal infection.
  Kroetz DN, Deepe GS
  J Immunol. 2010
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• Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.
  Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL, Thio CL
  J Infect Dis. 2010
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• Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations.
  Picton AC, Paximadis M, Tiemessen CT
  Infect Genet Evol. 2010
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• Genetic variation at the CCR5/CCR2 gene cluster and risk of psoriasis and psoriatic arthritis.
  Soto-Sánchez J, Santos-Juanes J, Coto-Segura P, Coto E, Díaz M, Rodríguez I, Alvarez V
  Cytokine. 2010
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• A haplotype in the CCR5 gene promoter was associated with the susceptibility to HIV-1 infection in a northern Chinese population.
  Xu L, Qiao Y, Zhang X, Sun H, Wang J, Sun D, Jia X, Shen C, Zhao Y, Jin Y, Yu Y, Ling H, Wang K, Fu S
  Mol Biol Rep. 2010
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• Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.
  Wang Y, Luk AO, Ma RC, So WY, Tam CH, Ng MC, Yang X, Baum L, Lam V, Tong PC, Chan JC
  Diabet Med. 2010
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• HIV infection and host genetic mutation among injecting drug-users of northeastern states of India.
  Sarkar K, Das SS, Pal R, Bal B, Madhusudan P, Chakraborti S
  J Health Popul Nutr. 2010
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• Conserved determinants of enhanced CCR5 binding in the human immunodeficiency virus subtype D envelope third variable loop.
  Teeravechyan S, Essex M, Lee TH
  AIDS Res Hum Retroviruses. 2010
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• New genetic associations detected in a host response study to hepatitis B vaccine.
  Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
  Genes Immun. 2010
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• Multiple common variants for celiac disease influencing immune gene expression.
  Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA
  Nat Genet. 2010
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• Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients.
  Hyde CL, Macinnes A, Sanders FA, Thompson JF, Mazzarella RA, Faergeman O, van Wijk DF, Wood L, Lira M, Paciga SA
  Circ Cardiovasc Genet. 2010
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• Evidences of the cooperative role of the chemokines CCL3, CCL4 and CCL5 and its receptors CCR1+ and CCR5+ in RANKL+ cell migration throughout experimental periodontitis in mice.
  Repeke CE, Ferreira SB, Claudino M, Silveira EM, de Assis GF, Avila-Campos MJ, Silva JS, Garlet GP
  Bone. 2010
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• Is long-term virological response related to CCR5 Delta32 deletion in HIV-1-infected patients started on highly active antiretroviral therapy?
  Laurichesse JJ, Taieb A, Capoulade-Metay C, Katlama C, Villes V, Drobacheff-Thiebaud MC, Raffi F, Chêne G, Theodorou I, Leport C, ANRS C08 Aproco-Copilote Study Group
  HIV Med. 2010
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• Donor and recipient chemokine receptor CCR5 genotype is associated with survival after bone marrow transplantation.
  McDermott DH, Conway SE, Wang T, Ricklefs SM, Agovi MA, Porcella SF, Tran HT, Milford E, Spellman S, Abdi R
  Blood. 2010
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• Short communication: identification of the conformational requirement for the specificities of coreceptors for human and simian immunodeficiency viruses.
  Shimizu N, Tanaka A, Jinno-Oue A, Mori T, Ohtsuki T, Hoshino H
  AIDS Res Hum Retroviruses. 2010
  PubMed ID: 20334567
   
  
• Linkage and haplotype analysis for chemokine receptors clustered on chromosome 3p21.3 and transmitted in family pedigrees with asthma and atopy.
  Al-Abdulhadi SA, Al-Rabia MW
  Ann Saudi Med. 2010
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• Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population.
  Chen DQ, Zeng Y, Zhou J, Yang L, Jiang S, Huang JD, Lu L, Zheng BJ
  J Med Virol. 2010
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• Immune regulation and vascular inflammation in genetic hypertension.
  Viel EC, Lemarié CA, Benkirane K, Paradis P, Schiffrin EL
  Am J Physiol Heart Circ Physiol. 2010
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• Chemokine polymorphisms and lymphoma: a pooled analysis.
  Bracci PM, Skibola CF, Conde L, Halperin E, Lightfoot T, Smith A, Paynter RA, Skibola DR, Agana L, Roman E, Kane E, Wiencke JK
  Leuk Lymphoma. 2010
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• Chemokine receptor CCR5 mediates alloimmune responses in graft-versus-host disease.
  Palmer LA, Sale GE, Balogun JI, Li D, Jones D, Molldrem JJ, Storb RF, Ma Q
  Biol Blood Marrow Transplant. 2010
  PubMed ID: 20025985
   
  
• Distribution of CCR5-Delta32, CCR5m303A, CCR2-64I and SDF1-3'A in HIV-1 infected and uninfected high-risk Uighurs in Xinjiang, China.
  Tan XH, Zhang JY, Di CH, Hu AR, Yang L, Qu S, Zhao RL, Yang PR, Guo SX
  Infect Genet Evol. 2010
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• Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.
  Karaali ZE, Sozen S, Yurdum M, Cacina C, Toptas B, Gok O, Agachan B
  Mol Biol Rep. 2010
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• Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice.
  Gregg RK, Nichols L, Chen Y, Lu B, Engelhard VH
  J Immunol. 2010
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• Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.
  Salem ML, Al-Khami AA, El-Naggar SA, Díaz-Montero CM, Chen Y, Cole DJ
  J Immunol. 2010
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• Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection.
  Chen J, Lau YF, Lamirande EW, Paddock CD, Bartlett JH, Zaki SR, Subbarao K
  J Virol. 2010
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• Toll-like receptor and chemokine receptor expression in HIV-infected T lymphocyte subsets.
  Miller Sanders C, Cruse JM, Lewis RE
  Exp Mol Pathol. 2010
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• CCR5 deficiency is a risk factor for early clinical manifestations of West Nile virus infection but not for viral transmission.
  Lim JK, McDermott DH, Lisco A, Foster GA, Krysztof D, Follmann D, Stramer SL, Murphy PM
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• C-C chemokine receptor 5 (CCR 5) polymorphisms in beryllium disease.
  Sato H, Silveira L, Spagnolo P, Gillespie M, Gottschall EB, Welsh KI, du Bois RM, Newman LS, Maier LA
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• Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice.
  Guabiraba R, Marques RE, Besnard AG, Fagundes CT, Souza DG, Ryffel B, Teixeira MM
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• GB virus C coinfection in advanced HIV type-1 disease is associated with low CCR5 and CXCR4 surface expression on CD4(+) T-cells.
  Schwarze-Zander C, Neibecker M, Othman S, Tural C, Clotet B, Blackard JT, Kupfer B, Luechters G, Chung RT, Rockstroh JK, Spengler U
  Antivir Ther. 2010
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• Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.
  Mamtani M, Matsubara T, Shimizu C, Furukawa S, Akagi T, Onouchi Y, Hata A, Fujino A, He W, Ahuja SK, Burns JC
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• Expression of Nef from unintegrated HIV-1 DNA downregulates cell surface CXCR4 and CCR5 on T-lymphocytes.
  Sloan RD, Donahue DA, Kuhl BD, Bar-Magen T, Wainberg MA
  Retrovirology. 2010
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• Effect of TNF-alpha genetic variants and CCR5 Delta 32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards.
  Veloso S, Olona M, García F, Domingo P, Alonso-Villaverde C, Broch M, Peraire J, Viladés C, Plana M, Pedrol E, López-Dupla M, Aguilar C, Gutiérrez M, Leon A, Tasias M, Gatell JM, Richart C, Vidal F
  BMC Med Genet. 2010
  PubMed ID: 20420684
   
  
• IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo.
  Stoddart CA, Keir ME, McCune JM
  PLoS Pathog. 2010
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• Regulation of CCR5 expression in human placenta: insights from a study of mother-to-child transmission of HIV in Malawi.
  Joubert BR, Franceschini N, Mwapasa V, North KE, Meshnick SR
  PLoS One. 2010
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• CCR5 expression on cells from HLA-matched unrelated marrow donors and graft-versus-host disease.
  Ma Q, Gooley TA, Storb RF
  Biol Blood Marrow Transplant. 2010
  PubMed ID: 20053336
   
  
• Do human polyoma viruses and human immunodeficiency virus share common co-receptors?
  Borissov K, Tsekov I, Gavazova R, Kalvatchev Z, Argirova R
  J Med Virol. 2010
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• Chemokine receptor Ccr5 deficiency induces alternative macrophage activation and improves long-term renal allograft outcome.
  Dehmel S, Wang S, Schmidt C, Kiss E, Loewe RP, Chilla S, Schlöndorff D, Gröne HJ, Luckow B
  Eur J Immunol. 2010
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• Differential modulation of CCR5-tropic human immunodeficiency virus-1 transfer from macrophages towards T cells under interleukin-4/interleukin-13 microenvironment.
  Saïdi H, Carbonneil C, Magri G, Eslahpazir J, Sekaly RP, Bélec L
  Hum Immunol. 2010
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• The chemokine receptor antagonist, TAK-779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function.
  Ni J, Zhu YN, Zhong XG, Ding Y, Hou LF, Tong XK, Tang W, Ono S, Yang YF, Zuo JP
  Br J Pharmacol. 2009
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• CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells.
  Basu S, Broxmeyer HE
  J Immunol. 2009
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• Beta-chemokine receptor CCR5 in human spermatozoa and its relationship with seminal parameters.
  Barbonetti A, Vassallo MR, Pelliccione F, D'Angeli A, Santucci R, Muciaccia B, Stefanini M, Francavilla F, Francavilla S
  Hum Reprod. 2009
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• Chemokine and chemokine receptor expression analysis in target organs of acute graft-versus-host disease.
  Bouazzaoui A, Spacenko E, Mueller G, Miklos S, Huber E, Holler E, Andreesen R, Hildebrandt GC
  Genes Immun. 2009
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• FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration.
  Toda E, Terashima Y, Sato T, Hirose K, Kanegasaki S, Matsushima K
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• Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
  Sohy D, Yano H, de Nadai P, Urizar E, Guillabert A, Javitch JA, Parmentier M, Springael JY
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• Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
  Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
  Am J Hum Genet. 2009
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• Association of CCR5-59029 A/G and CCL3L1 copy number polymorphism with HIV type 1 transmission/progression among HIV type 1-seropositive and repeatedly sexually exposed HIV type 1-seronegative North Indians.
  Rathore A, Chatterjee A, Sivarama P, Yamamoto N, Singhal PK, Dhole TN
  AIDS Res Hum Retroviruses. 2009
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• Common CCR 5 polymorphism in stroke: the CCR 5 delta32 polymorphism differentiates cardioembolism from other aetiologies of ischaemic cerebrovascular diseases.
  Kostulas N, Nikolaos K, Markaki I, Ioanna M, Kostulas V, Vasilios K, Hillert J, Jan H, Kostulas K, Konstantinos K
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• CCR5Delta32 genotype is associated with outcome in type 2 diabetes mellitus.
  Muntinghe FL, Gross S, Bakker SJ, Landman GW, van der Harst P, Bilo HJ, Navis G, Zuurman MW
  Diabetes Res Clin Pract. 2009
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• A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains.
  Johnston SH, Lobritz MA, Nguyen S, Lassen K, Delair S, Posta F, Bryson YJ, Arts EJ, Chou T, Lee B
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• Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4.
  Agrawal-Gamse C, Lee FH, Haggarty B, Jordan AP, Yi Y, Lee B, Collman RG, Hoxie JA, Doms RW, Laakso MM
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• CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
  Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
  Arthritis Rheum. 2009
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• Frequency of the CCR5-Delta32 polymorphism in the Maltese population at birth.
  Vidal C, Xuereb-Anastasi A
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• CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection.
  Kohlmeier JE, Cookenham T, Miller SC, Roberts AD, Christensen JP, Thomsen AR, Woodland DL
  J Immunol. 2009
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• Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide.
  Passos GF, Figueiredo CP, Prediger RD, Pandolfo P, Duarte FS, Medeiros R, Calixto JB
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• CCR5 is required for regulation of alloreactive T-cell responses to single class II MHC-mismatched murine cardiac grafts.
  Nozaki T, Rosenblum JM, Schenk AD, Ishii D, Fairchild RL
  Am J Transplant. 2009
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• Human immunodeficiency virus type 1 V1-to-V5 envelope variants from the chronic phase of infection use CCR5 and fuse more efficiently than those from early after infection.
  Etemad B, Fellows A, Kwambana B, Kamat A, Feng Y, Lee S, Sagar M
  J Virol. 2009
  PubMed ID: 19625411
   
  
• Chemokines released from astrocytes promote chemokine receptor 5-mediated neuronal cell differentiation.
  Park MH, Lee YK, Lee YH, Kim YB, Yun YW, Nam SY, Hwang SJ, Han SB, Kim SU, Hong JT
  Exp Cell Res. 2009
  PubMed ID: 19559698
   
  
• CCR5 deficiency induces astrocyte activation, Abeta deposit and impaired memory function.
  Lee YK, Kwak DH, Oh KW, Nam SY, Lee BJ, Yun YW, Kim YB, Han SB, Hong JT
  Neurobiol Learn Mem. 2009
  PubMed ID: 19394434
   
  
• Peripheral blood T4 cell surface CCR5 density as a marker of activity in rheumatoid arthritis treated with anti-CD20 monoclonal antibody.
  Portalès P, Fabre S, Vincent T, Desmetz C, Réant B, Noël D, Clot J, Jorgensen C, Corbeau P
  Immunology. 2009
  PubMed ID: 19740335
   
  
• Is CCR5-Delta32 mutation associated with diabetic nephropathy in type 2 diabetes?
  Arababadi MK, Naghavi N, Hassanshahi G, Mahmoodi M
  Ann Saudi Med. 2009
  PubMed ID: 19700905
   
  
• Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner.
  Baba T, Nakamoto Y, Mukaida N
  J Immunol. 2009
  PubMed ID: 19675159
   
  
• Toxoplasma gondii cyclophilin 18-mediated production of nitric oxide induces Bradyzoite conversion in a CCR5-dependent manner.
  Ibrahim HM, Bannai H, Xuan X, Nishikawa Y
  Infect Immun. 2009
  PubMed ID: 19564392
   
  
• Genetic interactions between the donor and the recipient for susceptibility to acute rejection in kidney transplantation: polymorphisms of CCR5.
  Cha RH, Yang SH, Kim HS, Kim SM, Park MH, Ha J, Kim YS
  Nephrol Dial Transplant. 2009
  PubMed ID: 19561149
   
  
• Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
  Schaier M, Vorwalder S, Sommerer C, Dikow R, Hug F, Gross ML, Waldherr R, Zeier M
  Am J Physiol Renal Physiol. 2009
  PubMed ID: 19535570
   
  
• Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics.
  Batra J, Ghosh B
  Genomics. 2009
  PubMed ID: 19520154
   
  
• CARD15/NOD2 polymorphisms are associated with severe pulmonary sarcoidosis.
  Sato H, Williams HR, Spagnolo P, Abdallah A, Ahmad T, Orchard TR, Copley SJ, Desai SR, Wells AU, du Bois RM, Welsh KI
  Eur Respir J. 2009
  PubMed ID: 19679608
   
  
• Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes.
  Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, for the EPICURO/Spanish Bladder Cancer Study investigators
  Eur Urol. 2009
  PubMed ID: 19692168
   
  
• CCR2-64I allele is associated with the progression of AIDS in a Han Chinese population.
  Xu L, Qiao Y, Zhang X, Sun H, Wang J, Sun D, Jin Y, Yu Y, Chen F, Bai J, Ling H, Wang K, Fu S
  Mol Biol Rep. 2009
  PubMed ID: 19669591
   
  
• Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
  Berro R, Sanders RW, Lu M, Klasse PJ, Moore JP
  PLoS Pathog. 2009
  PubMed ID: 19680536
   
  
• Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
  Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y
  Int J Mol Med. 2009
  PubMed ID: 19578796
   
  
• Donor variation in in vitro HIV-1 susceptibility of monocyte-derived macrophages.
  Bol SM, van Remmerden Y, Sietzema JG, Kootstra NA, Schuitemaker H, van't Wout AB
  Virology. 2009
  PubMed ID: 19535121
   
  
• Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice.
  Luckow B, Hänggli A, Maier H, Chilla S, Loewe RP, Dehmel S, Schlöndorff D, Loetscher P, Zerwes HG, Müller M
  Genesis. 2009
  PubMed ID: 19517561
   
  
• Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling.
  Song XY, Lee SY, Ma RC, So WY, Cai JH, Tam C, Lam V, Ying W, Ng MC, Chan JC
  Diabetologia. 2009
  PubMed ID: 19479237
   
  
• The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms.
  Sandford B, Bown M, London N, Sayers R
  Int J Immunogenet. 2009
  PubMed ID: 19476483
   
  
• CCL5/CCR5 axis promotes the motility of human oral cancer cells.
  Chuang JY, Yang WH, Chen HT, Huang CY, Tan TW, Lin YT, Hsu CJ, Fong YC, Tang CH
  J Cell Physiol. 2009
  PubMed ID: 19334035
   
  
• Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis.
  McDougal KE, Fallin MD, Moller DR, Song Z, Cutler DJ, Steiner LL, Cutting GR, ACCESS Research Group
  J Invest Dermatol. 2009
  PubMed ID: 19225544
   
  
• PTEN identified as important risk factor of chronic obstructive pulmonary disease.
  Hosgood HD, Menashe I, He X, Chanock S, Lan Q
  Respir Med. 2009
  PubMed ID: 19625176
   
  
• Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.
  Richter R, Casarosa P, Ständker L, Münch J, Springael JY, Nijmeijer S, Forssmann WG, Vischer HF, Vakili J, Detheux M, Parmentier M, Leurs R, Smit MJ
  J Immunol. 2009
  PubMed ID: 19553544
   
  
• Evaluation of the genetic background of standard-immunosuppressant-related toxicity in a cohort of 200 paediatric renal allograft recipients--a retrospective study.
  Grenda R, Prokurat S, Ciechanowicz A, Piatosa B, Kaliciński P
  Ann Transplant. 2009
  PubMed ID: 19644155
   
  
• CCR1 and CCR5 promote hepatic fibrosis in mice.
  Seki E, De Minicis S, Gwak GY, Kluwe J, Inokuchi S, Bursill CA, Llovet JM, Brenner DA, Schwabe RF
  J Clin Invest. 2009
  PubMed ID: 19603542
   
  
• The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity.
  Jeffrey PL, Wang Y, Seidl T, Babaahmady K, Vaughan R, Lehner T
  Eur J Immunol. 2009
  PubMed ID: 19585516
   
  
• A candidate gene association study of 77 polymorphisms in migraine.
  Schürks M, Kurth T, Buring JE, Zee RY
  J Pain. 2009
  PubMed ID: 19559392
   
  
• Distribution of CCR5 genotypes and HLA Class I B alleles in HIV-1 infected and uninfected injecting drug users from Rio de Janeiro, Brazil.
  Teixeira SL, Bastos FI, Hacker MA, Morgado MG
  Infect Genet Evol. 2009
  PubMed ID: 19460331
   
  
• CCR5 deletion protects against inflammation-associated mortality in dialysis patients.
  Muntinghe FL, Verduijn M, Zuurman MW, Grootendorst DC, Carrero JJ, Qureshi AR, Luttropp K, Nordfors L, Lindholm B, Brandenburg V, Schalling M, Stenvinkel P, Boeschoten EW, Krediet RT, Navis G, Dekker FW
  J Am Soc Nephrol. 2009
  PubMed ID: 19389855
   
  
• Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.
  Mikhak Z, Farsidjani A, Luster AD
  J Immunol. 2009
  PubMed ID: 19494319
   
  
• Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain.
  Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Sheffief S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, Gorry PR
  J Virol. 2009
  PubMed ID: 19321618
   
  
• CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic.
  Abraha A, Nankya IL, Gibson R, Demers K, Tebit DM, Johnston E, Katzenstein D, Siddiqui A, Herrera C, Fischetti L, Shattock RJ, Arts EJ
  J Virol. 2009
  PubMed ID: 19297481
   
  
• Characterization of HIV-2 chimeric viruses unable to use CCR5 and CXCR4 coreceptors.
  Santos-Costa Q, Mansinho K, Moniz-Pereira J, Azevedo-Pereira JM
  Virus Res. 2009
  PubMed ID: 19200444
   
  
• CCR5-Delta32 Allele is Associated with the Risk of Developing Multiple Sclerosis in the Iranian Population.
  Shahbazi M, Ebadi H, Fathi D, Roshandel D, Mahamadhoseeni M, Rashidbaghan A, Mahammadi N, Mahammadi MR, Zamani M
  Cell Mol Neurobiol. 2009
  PubMed ID: 19479371
   
  
• Perioperative Genomic Profiles Using Structure-Specific Oligonucleotide Probes.
  Hogan KJ, Burmester JK, Caldwell MD, Hogan QH, Coursin DB, Green DN, Selzer RM, Broderick TP, Rusy DA, Poroli M, Lutz AL, Sanders AM, Oldenburg MC, Koelbl JA, de Arruda-Indig M, Halsey JL, Day SP, Domanico MJ
  Clin Med Res. 2009
  PubMed ID: 19474452
   
  
• A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).
  Yamamoto R, Nagasawa Y, Shoji T, Inoue K, Uehata T, Kaneko T, Okada T, Yamauchi A, Tsubakihara Y, Imai E, Isaka Y, Rakugi H
  Nephrol Dial Transplant. 2009
  PubMed ID: 19420105
   
  
• Lineage-specific biology revealed by a finished genome assembly of the mouse.
  Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
  PLoS Biol. 2009
  PubMed ID: 19468303
   
  
• Role of CCR5 Delta32 bp deletion in RA and SLE.
  Martens HA, Kallenberg CG, Bijl M
  Autoimmunity. 2009
  PubMed ID: 19811270
   
  
• Analyses of associations with asthma in four asthma population samples from Canada and Australia.
  Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ
  Hum Genet. 2009
  PubMed ID: 19247692
   
  
• Genetic diversity of RANTES gene promoter and susceptibility to coronary artery disease and restenosis after percutaneous coronary intervention.
  Vogiatzi K, Voudris V, Apostolakis S, Kochiadakis GE, Thomopoulou S, Zaravinos A, Spandidos DA
  Thromb Res. 2009
  PubMed ID: 19201454
   
  
• Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
  Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q
  Environ Mol Mutagen. 2009
  PubMed ID: 19170196
   
  
• Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
  Zee RY, Bubes V, Shrivastava S, Ridker PM, Glynn RJ
  Clin Chim Acta. 2009
  PubMed ID: 19263529
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
  Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R
  Pediatr Infect Dis J. 2009
  PubMed ID: 19258923
   
  
• Cytokine (IL-10 -1082 and -819) and chemokine receptor (CCR2 and CCR5) gene polymorphism in North Indian patients with end-stage renal disease.
  Manchanda PK, Singh R, Mittal RD
  DNA Cell Biol. 2009
  PubMed ID: 19196047
   
  
• Differential upregulation of chemokine receptors on CD56 NK cells and their transmigration to the site of infection in tuberculous pleurisy.
  Pokkali S, Das SD, Selvaraj A
  FEMS Immunol Med Microbiol. 2009
  PubMed ID: 19159432
   
  
• Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.
  Anastassopoulou CG, Ketas TJ, Klasse PJ, Moore JP
  Proc Natl Acad Sci U S A. 2009
  PubMed ID: 19289833
   
  
• Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia.
  Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, Strayer DS
  J Gen Virol. 2009
  PubMed ID: 19218218
   
  
• CCR5 and p53 codon 72 gene polymorphisms: implications in breast cancer development.
  Aoki MN, da Silva do Amaral Herrera AC, Amarante MK, do Val Carneiro JL, Fungaro MH, Watanabe MA
  Int J Mol Med. 2009
  PubMed ID: 19212663
   
  
• A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
  Wang X, Cheng S, Brophy VH, Erlich HA, Mannhalter C, Berger K, Lalouschek W, Browner WS, Shi Y, Ringelstein EB, Kessler C, Luedemann J, Lindpaintner K, Liu L, Ridker PM, Zee RY, Cook NR, RMS Stroke SNP Consortium
  Stroke. 2009
  PubMed ID: 19131662
   
  
• Association between IL4 (-590), ACE (I)/(D), CCR5 (Delta32), CTLA4 (+49) and IL1-RN (VNTR in intron 2) gene polymorphisms and vitiligo.
  Pehlivan S, Ozkinay F, Alper S, Onay H, Yuksel E, Pehlivan M, Ozkinay C
  Eur J Dermatol. 2009
  PubMed ID: 19129082
   
  
• Role for CCR5 in dissemination of vaccinia virus in vivo.
  Rahbar R, Murooka TT, Fish EN
  J Virol. 2009
  PubMed ID: 19073715
   
  
• M- and T-tropic HIVs promote apoptosis in rat neurons.
  Bachis A, Biggio F, Major EO, Mocchetti I
  J Neuroimmune Pharmacol. 2009
  PubMed ID: 19034668
   
  
• CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
  Achour L, Scott MG, Shirvani H, Thuret A, Bismuth G, Labbé-Jullié C, Marullo S
  Blood. 2009
  PubMed ID: 19064722
   
  
• Relationship between expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4(+) T cells and spontaneous abortion in mice.
  Jiang PJ, Lin QD, Bao SM, Zhao AM, Zhang Y, Xiao SJ
  Chin Med J (Engl). 2009
  PubMed ID: 19302742
   
  
• Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120.
  Brower ET, Schön A, Klein JC, Freire E
  Biochemistry. 2009
  PubMed ID: 19170639
   
  
• Historic, demographic, and genetic evidence for increased population frequencies of CCR5Delta32 mutation in Croatian Island isolates after lethal 15th century epidemics.
  Biloglav Z, Zgaga L, Smoljanović M, Hayward C, Polasek O, Kolcić I, Vitart V, Zemunik T, Boraska V, Torlak V, Mulić R, Ropac D, Grković I, Rudan D, Ristić S, Barbalić M, Campbell H, Wright AF, Rudan I
  Croat Med J. 2009
  PubMed ID: 19260142
   
  
• CCR5 proinflammatory allele in prostate cancer risk: a pilot study in patients and centenarians from Sicily .
  Balistreri CR, Carruba G, Calabrò M, Campisi I, Di Carlo D, Lio D, Colonna-Romano G, Candore G, Caruso C
  Ann N Y Acad Sci. 2009
  PubMed ID: 19250219
   
  
• Chemotactic mediators of Th1 T-cell trafficking in smokers and COPD patients.
  Brozyna S, Ahern J, Hodge G, Nairn J, Holmes M, Reynolds PN, Hodge S
  COPD. 2009
  PubMed ID: 19229703
   
  
• Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer.
  Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, Eberlein TJ, Hsieh CS, Linehan DC
  J Immunol. 2009
  PubMed ID: 19155524
   
  
• Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection.
  van Manen D, Kootstra NA, Boeser-Nunnink B, Handulle MA, van't Wout AB, Schuitemaker H
  AIDS. 2009
  PubMed ID: 19050382
   
  
• Chemokine Receptor-5Delta32 Mutation is No Risk Factor for Ischemic-Type Biliary Lesion in Liver Transplantation.
  Heidenhain C, Puhl G, Moench C, Lautem A, Neuhaus P
  J Transplant. 2009
  PubMed ID: 20107582
   
  
• Fat-storing multilocular cells expressing CCR5 increase in the thymus with advancing age: potential role for CCR5 ligands on the differentiation and migration of preadipocytes.
  Mello Coelho V, Bunbury A, Rangel LB, Giri B, Weeraratna A, Morin PJ, Bernier M, Taub DD
  Int J Med Sci. 2009
  PubMed ID: 20046229
   
  
• Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
  Holmes MV, Shah T, Vickery C, Smeeth L, Hingorani AD, Casas JP
  PLoS One. 2009
  PubMed ID: 19956635
   
  
• [Genetic predisposition to multiple sclerosis as a polygenic autoimmune disease]
  Favorova OO, Favorov AV, Boĭko AN, Sudomoina MA, Andreevskiĭ TV, Alekseenkov AD, Kulakova OG, Gusev EI, Parmigiani G, Ochs MF
  Zh Nevrol Psikhiatr Im S S Korsakova. 2009
  PubMed ID: 19894308
   
  
• V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
  Bozek K, Thielen A, Sierra S, Kaiser R, Lengauer T
  PLoS One. 2009
  PubMed ID: 19816596
   
  
• Effects of the CCR5-Delta32 mutation on hepatitis C virus-specific immune responses in patients with haemophilia.
  Ahlenstiel G, Woitas RP, Iwan A, Nattermann J, Feldmann G, Rockstroh JK, Oldenburg J, Kupfer B, Sauerbruch T, Spengler U
  Immunol Invest. 2009
  PubMed ID: 19811439
   
  
• Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis.
  Rossol M, Pierer M, Arnold S, Keysser G, Burkhardt H, Baerwald C, Wagner U
  Arthritis Res Ther. 2009
  PubMed ID: 19538721
   
  
• Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis.
  Nyquist PA, Winkler CA, McKenzie LM, Yanek LR, Becker LC, Becker DM
  Cerebrovasc Dis. 2009
  PubMed ID: 19506371
   
  
• Sequence variants of chemokine receptor genes and susceptibility to HIV-1 infection.
  Parczewski M, Leszczyszyn-Pynka M, Kaczmarczyk M, Adler G, Binczak-Kuleta A, Loniewska B, Boron-Kaczmarska A, Ciechanowicz A
  J Appl Genet. 2009
  PubMed ID: 19433914
   
  
• Chemokine receptor and ligand upregulation in the diaphragm during endotoxemia and Pseudomonas lung infection.
  Demoule A, Divangahi M, Yahiaoui L, Danialou G, Gvozdic D, Petrof BJ
  Mediators Inflamm. 2009
  PubMed ID: 19421418
   
  
• Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.
  Ahluwalia TS, Khullar M, Ahuja M, Kohli HS, Bhansali A, Mohan V, Venkatesan R, Rai TS, Sud K, Singal PK
  PLoS One. 2009
  PubMed ID: 19357773
   
  
• Effects of the CCR5-Delta32 mutation on hepatitis C virus-specific immune responses in patients with haemophilia.
  Ahlenstiel G, Woitas RP, Iwan A, Nattermann J, Feldmann G, Rockstroh JK, Oldenburg J, Kupfer B, Sauerbruch T, Spengler U
  Immunol Invest. 2009
  PubMed ID: 19172482
   
  
• CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.
  Camargo JF, Quinones MP, Mummidi S, Srinivas S, Gaitan AA, Begum K, Jimenez F, VanCompernolle S, Unutmaz D, Ahuja SS, Ahuja SK
  J Immunol. 2009
  PubMed ID: 19109148
   
  
• Impact of chemokine receptor CCR2 and CCR5 gene polymorphism on allograft outcome in North Indian renal transplant recipients.
  Singh R, Kapoor R, Srivastava A, Mittal RD
  Scand J Immunol. 2009
  PubMed ID: 19037908
   
  
• Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay.
  Greisenegger S, Zehetmayer S, Bauer P, Endler G, Ferrari J, Lang W, Janisiw M, Steiner L, Cheng S, Lalouschek W, Mannhalter C
  Clin Chem. 2009
  PubMed ID: 19028820
   
  
• Association of chemokines receptor (CCR5 Delta32) in idiopathic recurrent miscarriages among north Indians.
  Parveen F, Tripathi G, Singh B, Agrawal S
  Arch Gynecol Obstet. 2008
  PubMed ID: 19116725
   
  
• Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection.
  Bierly AL, Shufesky WJ, Sukhumavasi W, Morelli AE, Denkers EY
  J Immunol. 2008
  PubMed ID: 19050266
   
  
• Distribution of HIV-1 resistant polymorphisms among HIV infected patients in Georgia.
  Karchava M, Nelson KE, Gochitashvili N, Dvali N, Tsertsvadze T
  Georgian Med News. 2008
  PubMed ID: 19124913
   
  
• Association of CCR5-59029 A/G and CCR2-V64I variants with renal allograft survival.
  Omrani MD, Mokhtari MR, Tagizadae A, Bagheri M, Ahmad-Poor P
  Iran J Immunol. 2008
  PubMed ID: 19098363
   
  
• MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.
  Sheahan T, Morrison TE, Funkhouser W, Uematsu S, Akira S, Baric RS, Heise MT
  PLoS Pathog. 2008
  PubMed ID: 19079579
   
  
• No association between common chemokine and chemokine receptor gene variants and prostate cancer risk.
  Petersen DC, Severi G, Hoang HN, Padilla EJ, Southey MC, English DR, Hopper JL, Giles GG, Hayes VM
  Cancer Epidemiol Biomarkers Prev. 2008
  PubMed ID: 19064579
   
  
• CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality.
  Fadel SA, Bromley SK, Medoff BD, Luster AD
  Eur J Immunol. 2008
  PubMed ID: 19039768
   
  
• High-affinity binding of southern African HIV type 1 subtype C envelope protein, gp120, to the CCR5 coreceptor.
  Fromme BJ, Coetsee M, Van Der Watt P, Chan MC, Sperling KM, Katz AA, Flanagan CA
  AIDS Res Hum Retroviruses. 2008
  PubMed ID: 19018669
   
  
• Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
  Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
  J Immunol. 2008
  PubMed ID: 19017998
   
  
• Interaction between RANTES promoter variant and CCR5Delta32 favors recovery from hepatitis B.
  Thio CL, Astemborski J, Thomas R, Mosbruger T, Witt MD, Goedert JJ, Hoots K, Winkler C, Thomas DL, Carrington M
  J Immunol. 2008
  PubMed ID: 19017985
   
  
• Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus.
  Abe J, Ueha S, Suzuki J, Tokano Y, Matsushima K, Ishikawa S
  Am J Pathol. 2008
  PubMed ID: 19008373
   
  
• Gene-expression profiles of peripheral blood mononuclear cell subpopulations in acute graft-vs-host disease following cord blood transplantation.
  Takahashi N, Sato N, Takahashi S, Tojo A
  Exp Hematol. 2008
  PubMed ID: 18814951
   
  
• MIP-3alpha and MIP-1alpha rapidly mobilize dendritic cell precursors into the peripheral blood.
  He S, Cao Q, Yoneyama H, Ge H, Zhang Y, Zhang Y
  J Leukoc Biol. 2008
  PubMed ID: 18791167
   
  
• CCR5 polymorphism and plague resistance in natural populations of the black rat in Madagascar.
  Tollenaere C, Rahalison L, Ranjalahy M, Rahelinirina S, Duplantier JM, Brouat C
  Infect Genet Evol. 2008
  PubMed ID: 18703167
   
  
• Effect of variation in RANTES promoter on serum RANTES levels and risk of recurrent wheezing after RSV bronchiolitis in children from Han, Southern China.
  Tian M, Liu F, Wen GY, Shi SY, Chen RH, Zhao DY
  Eur J Pediatr. 2008
  PubMed ID: 19005677
   
  
• G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity.
  Gamo K, Kiryu-Seo S, Konishi H, Aoki S, Matsushima K, Wada K, Kiyama H
  J Neurosci. 2008
  PubMed ID: 19005063
   
  
• Distribution of CCR5-Delta32, CCR2-64I, SDF1-3'A, CX3CR1-249I, and CX3CR1-280M in Chinese populations.
  Qian Y, Sun H, Lin K, Shi L, Shi L, Chu J
  AIDS Res Hum Retroviruses. 2008
  PubMed ID: 19032065
   
  
• Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells.
  Kang SJ, Liang HE, Reizis B, Locksley RM
  Immunity. 2008
  PubMed ID: 19006696
   
  
• Association of CCR5-delta32 mutation with reduced risk of nonatopic asthma in Slovenian children.
  Berce V, Repnik K, Potocnik U
  J Asthma. 2008
  PubMed ID: 18972295
   
  
• Frequency of CCR5-Delta32 deletion in human immunodeficiency virus type 1 (HIV-1) in healthy blood donors, HIV-1-exposed seronegative and HIV-1-seropositive individuals of southern Brazilian population.
  Reiche EM, Ehara Watanabe MA, Bonametti AM, Morimoto HK, Akira Morimoto A, Wiechmann SL, Matsuo T, Carvalho De Oliveira J, Vissoci Reiche F
  Int J Mol Med. 2008
  PubMed ID: 18949389
   
  
• CCR5 deficiency aggravates crescentic glomerulonephritis in mice.
  Turner JE, Paust HJ, Steinmetz OM, Peters A, Meyer-Schwesinger C, Heymann F, Helmchen U, Fehr S, Horuk R, Wenzel U, Kurts C, Mittrücker HW, Stahl RA, Panzer U
  J Immunol. 2008
  PubMed ID: 18941245
   
  
• CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process.
  Wu Y, Li YY, Matsushima K, Baba T, Mukaida N
  J Immunol. 2008
  PubMed ID: 18941229
   
  
• Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals.
  Singh KK, Hughes MD, Chen J, Phiri K, Rousseau C, Kuhn L, Coutsoudis A, Jackson JB, Guay LA, Musoke P, Mmiro F, Semba RD, Spector SA
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18845960
   
  
• SDF1-3'A Gene Mutation Is Correlated with Increased Susceptibility to HIV Type 1 Infection by Sexual Transmission in Han Chinese.
  Wang Y, Wang X, Peng J, Chen L, Cheng J, Nie S, Feng T, Zhao G, Zhao J, Shi X
  AIDS Res Hum Retroviruses. 2008
  PubMed ID: 18928397
   
  
• CD8 chemokine receptors in chronic obstructive pulmonary disease.
  Smyth LJ, Starkey C, Gordon FS, Vestbo J, Singh D
  Clin Exp Immunol. 2008
  PubMed ID: 18727632
   
  
• Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
  Hosgood HD, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q
  Carcinogenesis. 2008
  PubMed ID: 18676680
   
  
• Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice.
  Iida N, Nakamoto Y, Baba T, Kakinoki K, Li YY, Wu Y, Matsushima K, Kaneko S, Mukaida N
  J Leukoc Biol. 2008
  PubMed ID: 18644849
   
  
• Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
  Habermann TM, Wang SS, Maurer MJ, Morton LM, Lynch CF, Ansell SM, Hartge P, Severson RK, Rothman N, Davis S, Geyer SM, Cozen W, Chanock SJ, Cerhan JR
  Blood. 2008
  PubMed ID: 18633131
   
  
• Impact of Delta 32-CCR5 heterozygosity on HIV-1 genetic evolution and variability--a study of 4 individuals infected with closely related HIV-1 strains.
  Chalmet K, Van Wanzeele F, Demecheleer E, Dauwe K, Pelgrom J, Van Der Gucht B, Vogelaers D, Plum J, Stuyver L, Vandekerckhove L, Verhofstede C
  Virology. 2008
  PubMed ID: 18692212
   
  
• Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition.
  Maeda K, Das D, Yin PD, Tsuchiya K, Ogata-Aoki H, Nakata H, Norman RB, Hackney LA, Takaoka Y, Mitsuya H
  J Mol Biol. 2008
  PubMed ID: 18590744
   
  
• Better CD4+ T cell recovery in Brazilian HIV-infected individuals under HAART due to cumulative carriage of SDF-1-3'A, CCR2-V64I, CCR5-D32 and CCR5-promoter 59029A/G polymorphisms.
  Rigato PO, Hong MA, Casseb J, Ueda M, de Castro I, Benard G, Duarte AJ
  Curr HIV Res. 2008
  PubMed ID: 18855658
   
  
• Pathogenesis of herpetic stromal keratitis in CCR5- and/or CXCR3-deficient mice.
  Komatsu K, Miyazaki D, Morohoshi K, Kuo CH, Kakimaru-Hasegawa A, Komatsu N, Namba S, Haino M, Matsushima K, Inoue Y
  Curr Eye Res. 2008
  PubMed ID: 18798077
   
  
• Genetic factors that confer sensitivity to HAART in HIV-infected subjects: implication of a benefit of an earlier initiation of HAART.
  Nakajima T, Kimura A
  Pharmacogenomics. 2008
  PubMed ID: 18781860
   
  
• CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor.
  Kuipers HF, Biesta PJ, Montagne LJ, van Haastert ES, van der Valk P, van den Elsen PJ
  Blood. 2008
  PubMed ID: 18511806
   
  
• Downregulation of CCR5 on activated CD4 T cells in HIV-infected Indians.
  Dubey S, Khalid M, Wesley C, Khan SA, Wanchu A, Jameel S
  J Clin Virol. 2008
  PubMed ID: 18462992
   
  
• Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain.
  Ahmed F, Tessarollo L, Thiele C, Mocchetti I
  Brain Res. 2008
  PubMed ID: 18588860
   
  
• Cytokine expression after vaginal distention of different durations in virgin Sprague-Dawley rats.
  Wood HM, Kuang M, Woo L, Hijaz A, Butler RS, Penn M, Rackley R, Damaser MS
  J Urol. 2008
  PubMed ID: 18554634
   
  
• Dendritic cells preferentially transfer CXCR4-using human immunodeficiency virus type 1 variants to CD4+ T lymphocytes in trans.
  van Montfort T, Thomas AA, Pollakis G, Paxton WA
  J Virol. 2008
  PubMed ID: 18524826
   
  
• CXCR4-CCR5: a couple modulating T cell functions.
  Contento RL, Molon B, Boularan C, Pozzan T, Manes S, Marullo S, Viola A
  Proc Natl Acad Sci U S A. 2008
  PubMed ID: 18632580
   
  
• The CCR5 (-2135C/T) Polymorphism may be Associated with the Development of Kawasaki Disease in Korean Children.
  Jhang WK, Kang MJ, Jin HS, Yu J, Kim BJ, Kim BS, Lee JK, Seo EJ, Yoo HW, Park IS, Hong YM, Hong SJ
  J Clin Immunol. 2008
  PubMed ID: 18629619
   
  
• The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections.
  Kohlmeier JE, Miller SC, Smith J, Lu B, Gerard C, Cookenham T, Roberts AD, Woodland DL
  Immunity. 2008
  PubMed ID: 18617426
   
  
• CCR5 expression on macrophages/microglia is associated with early remyelination in multiple sclerosis lesions.
  Trebst C, König F, Ransohoff R, Brück W, Stangel M
  Mult Scler. 2008
  PubMed ID: 18611987
   
  
• C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.
  van Deventer HW, Wu QP, Bergstralh DT, Davis BK, O'Connor BP, Ting JP, Serody JS
  Am J Pathol. 2008
  PubMed ID: 18535183
   
  
• Independent Effects of Genetic Variations in Mannose-Binding Lectin Influence the Course of HIV Disease: The Advantage of Heterozygosity for Coding Mutations.
  Catano G, Agan BK, Kulkarni H, Telles V, Marconi VC, Dolan MJ, Ahuja SK
  J Infect Dis. 2008
  PubMed ID: 18498240
   
  
• Chemokine-receptor upregulation and disease severity in respiratory syncytial virus infection.
  Morrison PT, Sharland M, Thomas LH, Manna S, Handforth J, Tibby S, Friedland JS
  Clin Immunol. 2008
  PubMed ID: 18439876
   
  
• Type C coping, alexithymia, and heart rate reactivity are associated independently and differentially with specific immune mechanisms linked to HIV progression.
  Temoshok LR, Waldstein SR, Wald RL, Garzino-Demo A, Synowski SJ, Sun L, Wiley JA
  Brain Behav Immun. 2008
  PubMed ID: 18346864
   
  
• Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.
  Luttrell LM
  Mol Biotechnol. 2008
  PubMed ID: 18240029
   
  
• Expression of the chemokine antagonist vMIP II using a non-viral vector can prolong corneal allograft survival.
  Pillai RG, Beutelspacher SC, Larkin DF, George AJ
  Transplantation. 2008
  PubMed ID: 18551072
   
  
• Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.
  Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge JE, Abe J, Shono Y, Kitabatake M, Kakimi K, Mukaida N, Matsushima K
  Blood. 2008
  PubMed ID: 18375791
   
  
• An alteration of human immunodeficiency virus gp41 leads to reduced CCR5 dependence and CD4 independence.
  Taylor BM, Foulke JS, Flinko R, Heredia A, DeVico A, Reitz M
  J Virol. 2008
  PubMed ID: 18353949
   
  
• Functional Th1 cells are required for surgical adhesion formation in a murine model.
  Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
  J Immunol. 2008
  PubMed ID: 18453619
   
  
• CCR5 Delta32 polymorphism: associated with gallbladder cancer susceptibility.
  Srivastava A, Pandey SN, Choudhuri G, Mittal B
  Scand J Immunol. 2008
  PubMed ID: 18405329
   
  
• Female-specific association of C-C chemokine receptor 5 gene polymorphisms with Löfgren's syndrome.
  Fischer A, Valentonyte R, Nebel A, Nothnagel M, Müller-Quernheim J, Schürmann M, Schreiber S
  J Mol Med. 2008
  PubMed ID: 18311470
   
  
• Risk for HIV-1 infection is not associated with repeat-region polymorphism in the DC-SIGN neck domain and novel genetic DC-SIGN variants among North Indians.
  Rathore A, Chatterjee A, Sood V, Khan SZ, Banerjea AC, Yamamoto N, Dhole TN
  Clin Chim Acta. 2008
  PubMed ID: 18255039
   
  
• The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization.
  Chakera A, Seeber RM, John AE, Eidne KA, Greaves DR
  Mol Pharmacol. 2008
  PubMed ID: 18230715
   
  
• Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy.
  Ugurel S, Schrama D, Keller G, Schadendorf D, Bröcker EB, Houben R, Zapatka M, Fink W, Kaufman HL, Becker JC
  Cancer Immunol Immunother. 2008
  PubMed ID: 17909797
   
  
• Common CCR5-del32 Frameshift Mutation Associated With Serum Levels of Inflammatory Markers and Cardiovascular Disease Risk in the Bruneck Population.
  Afzal AR, Kiechl S, Daryani YP, Weerasinghe A, Zhang Y, Reindl M, Mayr A, Weger S, Xu Q, Willeit J
  Stroke. 2008
  PubMed ID: 18436884
   
  
• CCR5 is involved in controlling the early stage of Cryptosporidium parvum infection in neonates but is dispensable for parasite elimination.
  Lacroix-Lamandé S, Mancassola R, Auray G, Bernardet N, Laurent F
  Microbes Infect. 2008
  PubMed ID: 18403229
   
  
• T cell polarization identifies distinct clinical phenotypes in scleroderma lung disease.
  Boin F, De Fanis U, Bartlett SJ, Wigley FM, Rosen A, Casolaro V
  Arthritis Rheum. 2008
  PubMed ID: 18383361
   
  
• Role of polymorphisms of CC-chemokine receptor-5 gene in acute myocardial infarction and biological implications for longevity.
  Balistreri CR, Candore G, Caruso M, Incalcaterra E, Franceschi C, Caruso C
  Haematologica. 2008
  PubMed ID: 18379014
   
  
• Combined CXCR3/CCR5 blockade attenuates acute and chronic rejection.
  Schnickel GT, Bastani S, Hsieh GR, Shefizadeh A, Bhatia R, Fishbein MC, Belperio J, Ardehali A
  J Immunol. 2008
  PubMed ID: 18354195
   
  
• Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
  Terme M, Chaput N, Combadiere B, Ma A, Ohteki T, Zitvogel L
  J Immunol. 2008
  PubMed ID: 18354191
   
  
• Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice.
  Combadière C, Potteaux S, Rodero M, Simon T, Pezard A, Esposito B, Merval R, Proudfoot A, Tedgui A, Mallat Z
  Circulation. 2008
  PubMed ID: 18347211
   
  
• The CCR5 32-bp deletion allele is rare in a Chinese population.
  Wang F, Xiu MH, Zhou DF, Cao LY, Wu GY, Kosten TA, Kosten TR, Zhang XY
  Schizophr Res. 2008
  PubMed ID: 18295459
   
  
• The effects of RANTES/CCR5 promoter polymorphisms on HIV disease progression in HIV-infected Koreans.
  Jang DH, Choi BS, Kim SS
  Int J Immunogenet. 2008
  PubMed ID: 18218038
   
  
• Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages.
  Fantuzzi L, Spadaro F, Purificato C, Cecchetti S, Podo F, Belardelli F, Gessani S, Ramoni C
  Blood. 2008
  PubMed ID: 18203956
   
  
• A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation.
  Suzaki Y, Hamada K, Nomi T, Ito T, Sho M, Kai Y, Nakajima Y, Kimura H
  Eur Respir J. 2008
  PubMed ID: 18094012
   
  
• Host Genetic Influences on Highly Active Antiretroviral Therapy Efficacy and AIDS-Free Survival.
  Hendrickson SL, Jacobson LP, Nelson GW, Phair JP, Lautenberger J, Johnson RC, Kingsley L, Margolick JB, Detels R, Goedert JJ, O'Brien SJ
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18391751
   
  
• Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group.
  Davies SM, Borowitz MJ, Rosner GL, Ritz K, Devidas M, Winick N, Martin PL, Bowman P, Elliott J, Willman C, Das S, Cook EH, Relling MV
  Blood. 2008
  PubMed ID: 18182569
   
  
• [Markers of hepatitis B, C and HIV among orthopedic patients and staff at a Polish university hospital]
  Gańczak M, Bohatyrewicz A, Szych Z, Białecki P
  Chir Narzadow Ruchu Ortop Pol. 2008
  PubMed ID: 18846999
   
  
• CCR5-Dependent Regulatory T Cell Migration Mediates Fungal Survival and Severe Immunosuppression.
  Moreira AP, Cavassani KA, Massafera Tristão FS, Campanelli AP, Martinez R, Rossi MA, Silva JS
  J Immunol. 2008
  PubMed ID: 18292527
   
  
• Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice.
  Liu C, Lou Y, Lizée G, Qin H, Liu S, Rabinovich B, Kim GJ, Wang YH, Ye Y, Sikora AG, Overwijk WW, Liu YJ, Wang G, Hwu P
  J Clin Invest. 2008
  PubMed ID: 18259609
   
  
• Effects of CCR2 and CCRS polymorphisms on HIV-1 infection in Thai females.
  Wichukchinda N, Nakayama EE, Rojanawiwat A, Pathipvanich P, Auwanit W, Vongsheree S, Ariyoshi K, Sawanpanyalert P, Shioda T
  J Acquir Immune Defic Syndr. 2008
  PubMed ID: 18197127
   
  
• HIV-1 protecting CCR5-Delta32 allele in medieval Poland.
  Zawicki P, Witas HW
  Infect Genet Evol. 2008
  PubMed ID: 18162443
   
  
• Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists.
  Kondru R, Zhang J, Ji C, Mirzadegan T, Rotstein D, Sankuratri S, Dioszegi M
  Mol Pharmacol. 2008
  PubMed ID: 18096812
   
  
• CCR5Delta32 59537-G/A promoter polymorphism is associated with low translational efficiency and the loss of CCR5Delta32 protective effects.
  Jin Q, Agrawal L, Meyer L, Tubiana R, Theodorou I, Alkhatib G
  J Virol. 2008
  PubMed ID: 18094161
   
  
• Chemokine receptor 5 (CCR5) deletion polymorphism in North Indian patients with coronary artery disease.
  Sharda S, Gilmour A, Harris V, Singh VP, Sinha N, Tewari S, Ramesh V, Agrawal S, Mastana S
  Int J Cardiol. 2008
  PubMed ID: 17383752
   
  
• Chemokine system polymorphisms, survival and hepatocellular carcinoma occurrence in patients with hepatitis C virus-related cirrhosis.
  Nahon P, Sutton A, Rufat P, Simon C, Trinchet JC, Gattegno L, Beaugrand M, Charnaux N
  World J Gastroenterol. 2008
  PubMed ID: 18205260
   
  
• [Relationship between CCR5 gene polymorphism and condyloma acuminata]
  Zuo YG, Wang BX, Liu XR, Zhao P, Yan QS
  Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008
  PubMed ID: 18361062
   
  
• The chemokine CCL5 regulates the in vivo cell surface expression of its receptor, CCR5.
  Lin YL, Mettling C, Portalès P, Rouzier R, Clot J, Reynes J, Corbeau P
  AIDS. 2008
  PubMed ID: 18195571
   
  
• Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES.
  Borczuk AC, Papanikolaou N, Toonkel RL, Sole M, Gorenstein LA, Ginsburg ME, Sonett JR, Friedman RA, Powell CA
  Oncogene. 2008
  PubMed ID: 17653092
   
  
• A deletion in the chemokine receptor 5 (CCR5) gene is associated with tickborne encephalitis.
  Kindberg E, Mickiene A, Ax C, Akerlind B, Vene S, Lindquist L, Lundkvist A, Svensson L
  J Infect Dis. 2008
  PubMed ID: 18179389
   
  
• Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic.
  Lim JK, Louie CY, Glaser C, Jean C, Johnson B, Johnson H, McDermott DH, Murphy PM
  J Infect Dis. 2008
  PubMed ID: 18179388
   
  
• Initial spontaneous clearance and re-infection with a distinct hepatitis C virus genotype leading to chronic hepatitis C in an HIV+ intravenous drug user.
  Vispo E, Martinez-Alarcon J, Poveda E, Toro C, Soriano V
  AIDS. 2008
  PubMed ID: 18097239
   
  
• Analysis of the CC chemokine receptor 5Delta32 polymorphism in pediatric liver transplant recipients.
  Fischer-Maas L, Schneppenheim R, Oyen F, Grabhorn E, Richter A, Fischer L, Ganschow R
  Pediatr Transplant. 2008
  PubMed ID: 18194353
   
  
• Prevalence of a 32 bp deletion in the gene for human immunodeficiency virus 1 co-receptor ccr5 in slovak population.
  Takacova M, Nogova P, Habekova M, Stanekova D
  Acta Virol. 2008
  PubMed ID: 19143484
   
  
• Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis.
  Trinh L, Brignole-Baudouin F, Pauly A, Liang H, Houssier M, Baudouin C
  Mol Vis. 2008
  PubMed ID: 19104678
   
  
• Role of CCL3L1-CCR5 genotypes in the epidemic spread of HIV-1 and evaluation of vaccine efficacy.
  Kulkarni H, Marconi VC, Agan BK, McArthur C, Crawford G, Clark RA, Dolan MJ, Ahuja SK
  PLoS ONE. 2008
  PubMed ID: 18989363
   
  
• Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.
  Atik B, Skwor TA, Kandel RP, Sharma B, Adhikari HK, Steiner L, Erlich H, Dean D
  PLoS ONE. 2008
  PubMed ID: 18974840
   
  
• Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands.
  Guan Y, Abdelwahab S, Kamin-Lewis R, DeVico AL, Lewis GK
  PLoS ONE. 2008
  PubMed ID: 18941536
   
  
• Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors.
  Isik N, Hereld D, Jin T
  PLoS ONE. 2008
  PubMed ID: 18923649
   
  
• HIV-1 with multiple CCR5/CXCR4 chimeric receptor use is predictive of immunological failure in infected children.
  Cavarelli M, Karlsson I, Zanchetta M, Antonsson L, Plebani A, Giaquinto C, Fenyö EM, De Rossi A, Scarlatti G
  PLoS ONE. 2008
  PubMed ID: 18820725
   
  
• Essential contribution of CCL3 to alkali-induced corneal neovascularization by regulating vascular endothelial growth factor production by macrophages.
  Lu P, Li L, Wu Y, Mukaida N, Zhang X
  Mol Vis. 2008
  PubMed ID: 18776949
   
  
• CCL3L1-CCR5 genotype improves the assessment of AIDS Risk in HIV-1-infected individuals.
  Kulkarni H, Agan BK, Marconi VC, O'Connell RJ, Camargo JF, He W, Delmar J, Phelps KR, Crawford G, Clark RA, Dolan MJ, Ahuja SK
  PLoS ONE. 2008
  PubMed ID: 18776933
   
  
• CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.
  Oh DY, Jessen H, Kücherer C, Neumann K, Oh N, Poggensee G, Bartmeyer B, Jessen A, Pruss A, Schumann RR, Hamouda O
  PLoS ONE. 2008
  PubMed ID: 18648518
   
  
• Association study of CCR5 delta 32 polymorphism among the HLA-DRB1 Caucasian population in Northern Paraná, Brazil.
  Muxel SM, Borelli SD, Amarante MK, Voltarelli JC, Aoki MN, de Oliveira CE, Ehara Watanabe MA
  J Clin Lab Anal. 2008
  PubMed ID: 18623133
   
  
• Dissociation of heterotrimeric g proteins in cells.
  Lambert NA
  Sci Signal. 2008
  PubMed ID: 18577758
   
  
• CCR5-Delta32 polymorphism and susceptibility to cervical cancer: association with early stage of cervical cancer.
  Singh H, Sachan R, Jain M, Mittal B
  Oncol Res. 2008
  PubMed ID: 18543610
   
  
• SDF-1 and CCR5 Genes Polymorphism in Patients with Head and Neck Cancer.
  Khademi B, Razmkhah M, Erfani N, Gharagozloo M, Ghaderi A
  Pathol Oncol Res. 2008
  PubMed ID: 18386165
   
  
• Differential CCR5Delta32 allelic frequencies in juvenile idiopathic arthritis subtypes: evidence for different regulatory roles of CCR5 in rheumatological diseases.
  Scheibel I, Veit T, Neves AG, Souza L, Prezzi S, Machado S, Kohem C, Icarelli M, Xavier R, Brenol JC, Chies JA
  Scand J Rheumatol. 2008
  PubMed ID: 18189189
   
  
• Genetic control of chemokines in severe human internal carotid artery stenosis.
  Ghilardi G, Biondi ML, Turri O, Pateri F, d'Eril GM, Scorza R
  Cytokine. 2008
  PubMed ID: 18060801
   
  
• Analysis of CCR5, CCR2, SDF1 and RANTES gene polymorphisms in subjects with HIV-related PML and not determined leukoencephalopathy.
  Guerini FR, Delbue S, Zanzottera M, Agliardi C, Saresella M, Mancuso R, Maserati R, Marchioni E, Gori A, Ferrante P
  Biomed Pharmacother. 2008
  PubMed ID: 17560067
   
  
• Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.
  Hallgren J, Jones TG, Abonia JP, Xing W, Humbles A, Austen KF, Gurish MF
  Proc Natl Acad Sci U S A. 2007
  PubMed ID: 18077323
   
  
• Species selectivity of small-molecular antagonists for the CCR5 chemokine receptor.
  Saita Y, Kondo M, Shimizu Y
  Int Immunopharmacol. 2007
  PubMed ID: 17920529
   
  
• Identification of the CCR5-Delta32 HIV resistance allele and new mutations of the CCR5 gene in different Tunisian populations.
  Jlizi A, Edouard J, Fadhlaoui-Zid K, Frigi S, Debré P, Slim A, Theodorou I, El Gaaied AB, Carpentier W
  Hum Immunol. 2007
  PubMed ID: 18191728
   
  
• CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.
  Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK
  Nat Immunol. 2007
  PubMed ID: 17952079
   
  
• Identification of a postendocytic sorting sequence in CCR5.
  Delhaye M, Gravot A, Ayinde D, Niedergang F, Alizon M, Brelot A
  Mol Pharmacol. 2007
  PubMed ID: 17855654
   
  
• CCR5 signaling through phospholipase D involves p44/42 MAP-kinases and promotes HIV-1 LTR-directed gene expression.
  Paruch S, Heinis M, Lemay J, Hoeffel G, Marañón C, Hosmalin A, Périanin A
  FASEB J. 2007
  PubMed ID: 17627030
   
  
• CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach.
  Baker AM, Saulière A, Gaibelet G, Lagane B, Mazères S, Fourage M, Bachelerie F, Salomé L, Lopez A, Dumas F
  J Biol Chem. 2007
  PubMed ID: 17855336
   
  
• CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythematosus.
  Mamtani M, Rovin B, Brey R, Camargo JF, Kulkarni H, Herrera M, Correa P, Holliday S, Anaya JM, Ahuja SK
  Ann Rheum Dis. 2007
  PubMed ID: 17971457
   
  
• CC chemokine receptor 5 influences late-stage atherosclerosis.
  Quinones MP, Martinez HG, Jimenez F, Estrada CA, Dudley M, Willmon O, Kulkarni H, Reddick RL, Fernandes G, Kuziel WA, Ahuja SK, Ahuja SS
  Atherosclerosis. 2007
  PubMed ID: 17466311
   
  
• Genetic variability of major inflammatory mediators has no impact on the outcome of kidney transplantation.
  Brabcova I, Petrasek J, Hribova P, Hyklova K, Bartosova K, Lacha J, Viklický O
  Transplantation. 2007
  PubMed ID: 17989610
   
  
• Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice.
  Krohn R, Raffetseder U, Bot I, Zernecke A, Shagdarsuren E, Liehn EA, van Santbrink PJ, Nelson PJ, Biessen EA, Mertens PR, Weber C
  Circulation. 2007
  PubMed ID: 17893273
   
  
• Single nucleotide polymorphism of CC chemokine ligand 5 promoter gene in recipients may predict the risk of chronic graft-versus-host disease and its severity after allogeneic transplantation.
  Kim DH, Jung HD, Lee NY, Sohn SK
  Transplantation. 2007
  PubMed ID: 17984846
   
  
• Antibody-mediated rejection of cardiac allografts in CCR5-deficient recipients.
  Nozaki T, Amano H, Bickerstaff A, Orosz CG, Novick AC, Tanabe K, Fairchild RL
  J Immunol. 2007
  PubMed ID: 17911609
   
  
• Influence of insulin therapy on expression of chemokine receptor CCR5 and selected inflammatory markers in patients with type 2 diabetes mellitus.
  Bogdanski P, Pupek-Musialik D, Dytfeld J, Jagodzinski PP, Jablecka A, Kujawa A, Musialik K
  Int J Clin Pharmacol Ther. 2007
  PubMed ID: 17966842
   
  
• CCL5 and CCR5 genotypes modify clinical, radiological and pathological features of multiple sclerosis.
  van Veen T, Nielsen J, Berkhof J, Barkhof F, Kamphorst W, Bö L, Ravid R, Verweij CL, Huitinga I, Polman CH, Uitdehaag BM
  J Neuroimmunol. 2007
  PubMed ID: 17884183
   
  
• Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice.
  Bracke KR, D'hulst AI, Maes T, Demedts IK, Moerloose KB, Kuziel WA, Joos GF, Brusselle GG
  Clin Exp Allergy. 2007
  PubMed ID: 17883726
   
  
• Polymorphisms in CCR5 chemokine receptor gene in Japan.
  Liu H, Nakayama EE, Theodorou I, Nagai Y, Likanonsakul S, Wasi C, Debre P, Iwamoto A, Shioda T
  Int J Immunogenet. 2007
  PubMed ID: 17845302
   
  
• Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.
  Breunis WB, Biezeveld MH, Geissler J, Kuipers IM, Lam J, Ottenkamp J, Hutchinson A, Welch R, Chanock SJ, Kuijpers TW
  Clin Exp Immunol. 2007
  PubMed ID: 17672867
   
  
• Peptide mimotopes selected with HIV-1-blocking monoclonal antibodies against CCR5 represent motifs specific for HIV-1 entry.
  Königs C, Pustowka A, Irving J, Kessel C, Klich K, Wegner V, Rowley MJ, Mackay IR, Kreuz W, Griesinger C, Dietrich U
  Immunol Cell Biol. 2007
  PubMed ID: 17607321
   
  
• Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.
  Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD
  Science. 2007
  PubMed ID: 17901336
   
  
• The human CC chemokine MIP-1beta dimer is not competent to bind to the CCR5 receptor.
  Jin H, Shen X, Baggett BR, Kong X, LiWang PJ
  J Biol Chem. 2007
  PubMed ID: 17644519
   
  
• Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
  Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B
  J Infect Dis. 2007
  PubMed ID: 17703412
   
  
• Structural and functional characterization of CC chemokine CCL14.
  Blain KY, Kwiatkowski W, Zhao Q, La Fleur D, Naik C, Chun TW, Tsareva T, Kanakaraj P, Laird MW, Shah R, George L, Sanyal I, Moore PA, Demeler B, Choe S
  Biochemistry. 2007
  PubMed ID: 17691823
   
  
• The chemokine receptor CCR5 genetic polymorphism and expression in rheumatoid arthritis patients.
  Kohem CL, Brenol JC, Xavier RM, Bredemeier M, Brenol CV, Dedavid e Silva TL, de Castilhos Mello A, Cañedo AD, Neves AG, Chies JA
  Scand J Rheumatol. 2007
  PubMed ID: 17963165
   
  
• CCR5-Delta32 genetic polymorphism associated with benign clinical course and magnetic resonance imaging findings in Brazilian patients with multiple sclerosis.
  Kaimen-Maciel DR, Reiche EM, Brum Souza DG, Frota Comini ER, Bobroff F, Morimoto HK, Ehara Watanabe MA, Carvalho De Oliveira J, Matsuo T, Lopes J, Donadi EA
  Int J Mol Med. 2007
  PubMed ID: 17671738
   
  
• Dynamic imaging of chemokine-dependent CD8+ T cell help for CD8+ T cell responses.
  Hugues S, Scholer A, Boissonnas A, Nussbaum A, Combadière C, Amigorena S, Fetler L
  Nat Immunol. 2007
  PubMed ID: 17660821
   
  
• CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.
  Freeman CM, Curtis JL, Chensue SW
  Am J Pathol. 2007
  PubMed ID: 17640964
   
  
• CCR5 and CXCR3 are dispensable for liver infiltration, but CCR5 protects against virus-induced T-cell-mediated hepatic steatosis.
  Holst PJ, Orskov C, Qvortrup K, Christensen JP, Thomsen AR
  J Virol. 2007
  PubMed ID: 17626099
   
  
• Acute cellular allograft rejection in homozygous CCR5 Delta32 patients after renal transplantation.
  Steinmetz OM, Fischereder M, Weiss M, Helmchen U, Stahl RA, Panzer U
  Transplantation. 2007
  PubMed ID: 17713445
   
  
• Porphyromonas gingivalis selectively up-regulates the HIV-1 coreceptor CCR5 in oral keratinocytes.
  Giacaman RA, Nobbs AH, Ross KF, Herzberg MC
  J Immunol. 2007
  PubMed ID: 17675516
   
  
• CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats.
  Machado RR, Soares DM, Proudfoot AE, Souza GE
  Brain Res. 2007
  PubMed ID: 17604006
   
  
• Deletion of CCR2 but not CCR5 or CXCR3 inhibits aortic aneurysm formation.
  MacTaggart JN, Xiong W, Knispel R, Baxter BT
  Surgery. 2007
  PubMed ID: 17689697
   
  
• Controls for lung dendritic cell maturation and migration during respiratory viral infection.
  Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, Agapov E, Holtzman MJ
  J Immunol. 2007
  PubMed ID: 17641009
   
  
• Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission.
  Moutsopoulos NM, Nares S, Nikitakis N, Rangel Z, Wen J, Munson P, Sauk J, Wahl SM
  Am J Pathol. 2007
  PubMed ID: 17620369
   
  
• CCR5Delta32 protein expression and stability are critical for resistance to human immunodeficiency virus type 1 in vivo.
  Agrawal L, Jin Q, Altenburg J, Meyer L, Tubiana R, Theodorou I, Alkhatib G
  J Virol. 2007
  PubMed ID: 17522201
   
  
• Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching.
  Pastore C, Nedellec R, Ramos A, Hartley O, Miamidian JL, Reeves JD, Mosier DE
  J Virol. 2007
  PubMed ID: 17507486
   
  
• Influence of CCR5-Delta32 genotype in Spanish population with multiple sclerosis.
  Otaegui D, Ruíz-Martínez J, Olaskoaga J, Emparanza JI, de Munain AL
  Neurogenetics. 2007
  PubMed ID: 17351762
   
  
• Allelic distribution of the CCR5, CCR2, and SDF1 gene polymorphisms associated with HIV-1/AIDS resistance in Russian populations.
  Kofiadi IA, Rebrikov DV, Trofimov DY, Alexeev LP, Khaitov RM
  Dokl Biol Sci. 2007
  PubMed ID: 17929678
   
  
• The presence of functional CCR5 and EBV reactivation after allogeneic haematopoietic stem cell transplantation.
  Bogunia-Kubik K, Jaskula E, Lange A
  Bone Marrow Transplant. 2007
  PubMed ID: 17530006
   
  
• Analysis of CC chemokine receptor 5 and 2 polymorphisms and renal transplant survival.
  Yigit B, Bozkurt N, Berber I, Titiz I, Isbir T
  Cell Biochem Funct. 2007
  PubMed ID: 16598837
   
  
• Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-gamma signaling.
  Turner SJ, Olivas E, Gutierrez A, Diaz G, Doherty PC
  J Immunol. 2007
  PubMed ID: 17548597
   
  
• CCR4-dependent regulatory T cell function in inflammatory bowel disease.
  Yuan Q, Bromley SK, Means TK, Jones KJ, Hayashi F, Bhan AK, Luster AD
  J Exp Med. 2007
  PubMed ID: 17548518
   
  
• RANTES, MCP-1, CCR2, CCR5, CXCR1 and CXCR4 gene polymorphisms are not associated with the outcome of hepatitis B virus infection: results from a large scale single ethnic population.
  Cheong JY, Cho SW, Choi JY, Lee JA, Kim MH, Lee JE, Hahm KB, Kim JH
  J Korean Med Sci. 2007
  PubMed ID: 17596666
   
  
• CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis.
  Ajuebor MN, Wondimu Z, Hogaboam CM, Le T, Proudfoot AE, Swain MG
  Am J Pathol. 2007
  PubMed ID: 17525265
   
  
• Chemokine receptor CCR5 in interferon-treated multiple sclerosis.
  Sellebjerg F, Kristiansen TB, Wittenhagen P, Garred P, Eugen-Olsen J, Frederiksen JL, Sørensen TL
  Acta Neurol Scand. 2007
  PubMed ID: 17511851
   
  
• CCR5 Delta 32 mutation, Mycoplasma pneumoniae infection, and asthma.
  Ungvári I, Tölgyesi G, Semsei AF, Nagy A, Radosits K, Keszei M, Kozma GT, Falus A, Szalai C
  J Allergy Clin Immunol. 2007
  PubMed ID: 17445875
   
  
• Culture and differentiation of preadipocytes in two-dimensional and three-dimensional in vitro systems.
  Daya S, Loughlin AJ, Macqueen HA
  Differentiation. 2007
  PubMed ID: 17286602
   
  
• [Population study of the Udmurt population: analysis of ten polymorphic DNA loci of the nuclear genome]
  Bermisheva MA, Petrova NV, Zinchenko RA, Timkovskaia EE, Malyshev PIu, Gavrilina SG, Ginter EK, Kusnutdinova EK
  Genetika. 2007
  PubMed ID: 17633563
   
  
• Polymorphism in the CCR5 gene promoter and HIV-1 infection in North Indians.
  Kaur G, Singh P, Rapthap CC, Kumar N, Vajpayee M, Sharma SK, Wanchu A, Mehra NK
  Hum Immunol. 2007
  PubMed ID: 17462514
   
  
• Inhibition of chemokine receptor CCR2 and CCR5 expression contributes to simvastatin-induced attenuation of cardiac allograft vasculopathy.
  Yin R, Zhu J, Shao H, Cheng X, Feng X, Li Z, Jing H
  J Heart Lung Transplant. 2007
  PubMed ID: 17449418
   
  
• Production of specific mRNA transcripts, usage of an alternate promoter, and octamer-binding transcription factors influence the surface expression levels of the HIV coreceptor CCR5 on primary T cells.
  Mummidi S, Adams LM, VanCompernolle SE, Kalkonde M, Camargo JF, Kulkarni H, Bellinger AS, Bonello G, Tagoh H, Ahuja SS, Unutmaz D, Ahuja SK
  J Immunol. 2007
  PubMed ID: 17442950
   
  
• Lack of association of some chemokine system polymorphisms with the risks of death and hepatocellular carcinoma occurrence in patients with alcoholic cirrhosis: a prospective study.
  Nahon P, Sutton A, Rufat P, Faisant C, Simon C, Barget N, Trinchet JC, Beaugrand M, Gattegno L, Charnaux N
  Eur J Gastroenterol Hepatol. 2007
  PubMed ID: 17413295
   
  
• Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
  Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV
  J Immunol. 2007
  PubMed ID: 17404315
   
  
• CCR5 genotypes and progression to HIV disease in perinatally infected children.
  de Angelis DS, Freire WS, Pannuti CS, Succi RC, Machado DM
  Braz J Infect Dis. 2007
  PubMed ID: 17625759
   
  
• Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection.
  Oswald-Richter K, Grill SM, Leelawong M, Tseng M, Kalams SA, Hulgan T, Haas DW, Unutmaz D
  PLoS Pathog. 2007
  PubMed ID: 17465678
   
  
• CCR5 receptor: biologic and genetic implications in age-related diseases.
  Balistreri CR, Caruso C, Grimaldi MP, Listì F, Vasto S, Orlando V, Campagna AM, Lio D, Candore G
  Ann N Y Acad Sci. 2007
  PubMed ID: 17460174
   
  
• Prevalence of CCR5Delta32 polymorphism in long-term survivors of heart transplantation.
  Hummel M, Bara C, Hirt S, Haverich A, Hetzer R
  Transpl Immunol. 2007
  PubMed ID: 17331851
   
  
• Interleukin-24, RANTES and CCR5 gene polymorphisms are not associated with chronic adult periodontitis.
  Savarrio L, Donati M, Carr C, Kinane DF, Berglundh T
  J Periodontal Res. 2007
  PubMed ID: 17305874
   
  
• Susceptibility of CCR5-deficient mice to genital herpes simplex virus type 2 is linked to NK cell mobilization.
  Thapa M, Kuziel WA, Carr DJ
  J Virol. 2007
  PubMed ID: 17267483
   
  
• Melanoma susceptibility and progression: Association study between polymorphisms of the chemokine (CCL2) and chemokine receptors (CX3CR1, CCR5).
  Rodero M, Rodero P, Descamps V, Lebbe C, Wolkenstein P, Aegerter P, Vitoux D, Basset-Seguin N, Dupin N, Grandchamp B, Soufir N, Combadière C, Saiag P, Melan-cohort investigators
  J Dermatol Sci. 2007
  PubMed ID: 17169533
   
  
• Mutations in the V3 stem versus the V3 crown and C4 region have different effects on the binding and fusion steps of human immunodeficiency virus type 1 gp120 interaction with the CCR5 coreceptor.
  Suphaphiphat P, Essex M, Lee TH
  Virology. 2007
  PubMed ID: 17101166
   
  
• Deletion of the chemokine receptor CCR1 prolongs corneal allograft survival.
  Hamrah P, Yamagami S, Liu Y, Zhang Q, Vora SS, Lu B, Gerard CJ, Dana MR
  Invest Ophthalmol Vis Sci. 2007
  PubMed ID: 17325167
   
  
• Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration.
  Ishida Y, Kimura A, Kondo T, Hayashi T, Ueno M, Takakura N, Matsushima K, Mukaida N
  Am J Pathol. 2007
  PubMed ID: 17322370
   
  
• Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: implications of the interaction with chemokine receptor CCR5.
  Morikis D, Rizos AK, Spandidos DA, Krambovitis E
  Int J Mol Med. 2007
  PubMed ID: 17273779
   
  
• Distribution of CCR5delta32, CCR2-64I and SDF1-3'A and plasma levels of SDF-1 in HIV-1 seronegative North Indians.
  Verma R, Gupta RB, Singh K, Bhasin R, Anand Shukla A, Chauhan SS, Luthra K
  J Clin Virol. 2007
  PubMed ID: 17240189
   
  
• Distribution of the HIV resistance CCR5-Delta32 allele among Egyptians and Syrians.
  Salem AH, Batzer MA
  Mutat Res. 2007
  PubMed ID: 17166523
   
  
• Inhibition of HIV-1 infection by synthetic peptides derived CCR5 fragments.
  Imai M, Baranyi L, Okada N, Okada H
  Biochem Biophys Res Commun. 2007
  PubMed ID: 17210123
   
  
• Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon.
  Torimiro JN, Wolfe ND, Thomas A, Martin MP, Mpoudi-Ngole E, Tamoufe U, Birx DL, Carrington M, Burke DS, Carr JK
  AIDS. 2007
  PubMed ID: 17301575
   
  
• High prevalence of the CCR5Delta32 HIV-resistance mutation among Estonian HIV type 1-infected individuals.
  Adojaan M, Mölder T, Männik A, Kivisild T, Villems R, Krispin T, Ustav M
  AIDS Res Hum Retroviruses. 2007
  PubMed ID: 17331026
   
  
• Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells.
  Pido-Lopez J, Whittall T, Wang Y, Bergmeier LA, Babaahmady K, Singh M, Lehner T
  J Immunol. 2007
  PubMed ID: 17237417
   
  
• Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.
  Braunersreuther V, Zernecke A, Arnaud C, Liehn EA, Steffens S, Shagdarsuren E, Bidzhekov K, Burger F, Pelli G, Luckow B, Mach F, Weber C
  Arterioscler Thromb Vasc Biol. 2007
  PubMed ID: 17138939
   
  
• Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux.
  Melar M, Ott DE, Hope TJ
  J Virol. 2007
  PubMed ID: 17121788
   
  
• Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a cohort of Spanish HIV-1-infected subjects.
  Viladés C, Broch M, Plana M, Domingo P, Alonso-Villaverde C, Pedrol E, Knobel H, Dalmau D, Peraire J, Gutiérrez C, López A, Sambeat MA, Olona M, Garcia F, Richart C, Gatell JM, Vidal F, Chemokines and Long-Term Nonprogressors Study Group
  J Acquir Immune Defic Syndr. 2007
  PubMed ID: 17091019
   
  
• A closed-tube assay for genotyping of the 32-bp deletion polymorphism in the chemokine receptor 5 (CCR5) gene: dissociation analysis of amplified fragments of DNA.
  Rasmussen H, Werge T
  Mol Cell Probes. 2007
  PubMed ID: 16879946
   
  
• HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.
  Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA
  Cell Death Differ. 2007
  PubMed ID: 16841089
   
  
• Recognition of RANTES by extracellular parts of the CCR5 receptor.
  Duma L, Häussinger D, Rogowski M, Lusso P, Grzesiek S
  J Mol Biol. 2007
  PubMed ID: 17101151
   
  
• Alloantigen-enhanced accumulation of CCR5+ 'effector' regulatory T cells in the gravid uterus.
  Kallikourdis M, Andersen KG, Welch KA, Betz AG
  Proc Natl Acad Sci U S A. 2007
  PubMed ID: 17197426
   
  
• Interaction between allelic variation in IL12B and CCR5 affects the development of AIDS: IL12B/CCR5 interaction and HIV/AIDS.
  Gabutero E, Moore C, Mallal S, Stewart G, Williamson P
  AIDS. 2007
  PubMed ID: 17148969
   
  
• Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors.
  Bhangoo S, Ren D, Miller RJ, Henry KJ, Lineswala J, Hamdouchi C, Li B, Monahan PE, Chan DM, Ripsch MS, White FA
  Mol Pain. 2007
  PubMed ID: 18076762
   
  
• Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages.
  Sundaravaradan V, Das SR, Ramakrishnan R, Sehgal S, Gopalan S, Ahmad N, Jameel S
  Virol J. 2007
  PubMed ID: 18036244
   
  
• Complementary DNA microarray analysis of chemokines and their receptors in allergic rhinitis.
  Zhang RX, Yu SQ, Jiang JZ, Liu GJ
  J Investig Allergol Clin Immunol. 2007
  PubMed ID: 17982926
   
  
• CCR5 haplotypes and mother-to-child HIV transmission in Malawi.
  Pedersen BR, Kamwendo D, Blood M, Mwapasa V, Molyneux M, North K, Rogerson SJ, Zimmerman P, Meshnick SR
  PLoS ONE. 2007
  PubMed ID: 17786209
   
  
• The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment.
  Melikyan GB, Platt EJ, Kabat D
  Retrovirology. 2007
  PubMed ID: 17686153
   
  
• CD4-independent use of the CCR5 receptor by sequential primary SIVsm isolates.
  Laurén A, Vincic E, Hoshino H, Thorstensson R, Fenyö EM
  Retrovirology. 2007
  PubMed ID: 17645788
   
  
• The significant role of RANTES and CCR5 in progressive tubulointerstitial lesions in lupus nephropathy.
  Stasikowska O, Danilewicz M, Wagrowska-Danilewicz M
  Pol J Pathol. 2007
  PubMed ID: 17585540
   
  
• Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis.
  Lindner E, Nordang GB, Melum E, Flatø B, Selvaag AM, Thorsby E, Kvien TK, Førre OT, Lie BA
  BMC Med Genet. 2007
  PubMed ID: 17565662
   
  
• Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE.
  Eltayeb S, Berg AL, Lassmann H, Wallström E, Nilsson M, Olsson T, Ericsson-Dahlstrand A, Sunnemark D
  J Neuroinflammation. 2007
  PubMed ID: 17484785
   
  
• Association of TGFbeta1, TNFalpha, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians.
  Prasad P, Tiwari AK, Kumar KM, Ammini AC, Gupta A, Gupta R, Thelma BK
  BMC Med Genet. 2007
  PubMed ID: 17428349
   
  
• Polymorphisms of chemokine and chemokine receptor genes in idiopathic immune-mediated posterior segment uveitis.
  Ahad MA, Missotten T, Abdallah A, Lympany PA, Lightman S
  Mol Vis. 2007
  PubMed ID: 17417600
   
  
• Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
  Huang HY, Thuita L, Strickland P, Hoffman SC, Comstock GW, Helzlsouer KJ
  BMC Genet. 2007
  PubMed ID: 17355643
   
  
• Analysis of the CC chemokine receptor 5 delta32 polymorphism in a Brazilian population with cutaneous leishmaniasis.
  Brajão de Oliveira K, Reiche EM, Kaminami Morimoto H, Pelegrinelli Fungaro MH, Estevão D, Pontello R, Franco Nasser T, Watanabe MA
  J Cutan Pathol. 2007
  PubMed ID: 17214851
   
  
• Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.
  Tacke F, Alvarez D, Kaplan TJ, Jakubzick C, Spanbroek R, Llodra J, Garin A, Liu J, Mack M, van Rooijen N, Lira SA, Habenicht AJ, Randolph GJ
  J Clin Invest. 2007
  PubMed ID: 17200718
   
  
• Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis.
  Nakamura H, Higashikawa F, Nobukuni Y, Miyagawa K, Endo T, Imai T, Hatta K, Ozasa K, Motohashi Y, Matsuzaki I, Sasahara S, Ogino K, Akimaru K, Eboshida A
  Int Arch Allergy Immunol. 2007
  PubMed ID: 17135764
   
  
• Genetic protection against hepatitis B virus conferred by CCR5Delta32: Evidence that CCR5 contributes to viral persistence.
  Thio CL, Astemborski J, Bashirova A, Mosbruger T, Greer S, Witt MD, Goedert JJ, Hilgartner M, Majeske A, O'Brien SJ, Thomas DL, Carrington M
  J Virol. 2007
  PubMed ID: 17079285
   
  
• CCR5 interactions with the variable 3 loop of gp120.
  Napier KB, Wang ZX, Peiper SC, Trent JO
  J Mol Model. 2007
  PubMed ID: 16721558
   
  
• Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease.
  Apostolakis S, Baritaki S, Kochiadakis GE, Igoumenidis NE, Panutsopulos D, Spandidos DA
  Thromb Res. 2007
  PubMed ID: 16480760
   
  
• Frequency of the CCR5-delta32 mutation in the Atlantic island populations of Madeira, the Azores, Cabo Verde, and São Tomé e Príncipe.
  Freitas T, Brehm A, Fernandes AT
  Hum Biol. 2006
  PubMed ID: 17564248
   
  
• Role of CXCR3 and CCR5 in allograft rejection.
  Schnickel GT, Hsieh GR, Garcia C, Shefizadeh A, Fishbein MC, Ardehali A
  Transplant Proc. 2006
  PubMed ID: 17175228
   
  
• CCR5 deletion mutation and its association with the risk of developing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
  Bogunia-Kubik K, Duda D, Suchnicki K, Lange A
  Haematologica. 2006
  PubMed ID: 17145599
   
  
• Association of genetic variations in CCR5 and its ligand, RANTES with clearance of hepatitis B virus in Korea.
  Ahn SH, Kim do Y, Chang HY, Hong SP, Shin JS, Kim YS, Kim H, Kim JK, Paik YH, Lee KS, Chon CY, Moon YM, Han KH
  J Med Virol. 2006
  PubMed ID: 17063508
   
  
• Chemokine receptor CCR5 deficiency exacerbates cerulein-induced acute pancreatitis in mice.
  Moreno C, Nicaise C, Gustot T, Quertinmont E, Nagy N, Parmentier M, Louis H, Devière J
  Am J Physiol Gastrointest Liver Physiol. 2006
  PubMed ID: 16891300
   
  
• HIV gp120-induced interaction between CD4 and CCR5 requires cholesterol-rich microenvironments revealed by live cell fluorescence resonance energy transfer imaging.
  Yi L, Fang J, Isik N, Chim J, Jin T
  J Biol Chem. 2006
  PubMed ID: 16963439
   
  
• Polymorphisms in CCL2&CCL5 chemokines/chemokine receptors genes and their association with diseases.
  Navratilova Z
  Biomed Pap Med Fac Univ Palacky Olomouc Czech Repu. 2006
  PubMed ID: 17426779
   
  
• Association between the polymorphism of CCR5 and Alzheimer's disease: results of a study performed on male and female patients from Northern Italy.
  Balistreri CR, Grimaldi MP, Vasto S, Listi F, Chiappelli M, Licastro F, Lio D, Caruso C, Candore G
  Ann N Y Acad Sci. 2006
  PubMed ID: 17261788
   
  
• CCR5-, DC-SIGN-dependent endocytosis and delayed reverse transcription after human immunodeficiency virus type 1 infection in human astrocytes.
  Deiva K, Khiati A, Hery C, Salim H, Leclerc P, Horellou P, Tardieu M
  AIDS Res Hum Retroviruses. 2006
  PubMed ID: 17147503
   
  
• Simvastatin down regulates mRNA expression of RANTES and CCR5 in posttransplant renal recipients with hyperlipidemia.
  Li Q, Wang D, Wang Y, Xu Q
  Transplant Proc. 2006
  PubMed ID: 17112859
   
  
• Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression.
  Ariel A, Fredman G, Sun YP, Kantarci A, Van Dyke TE, Luster AD, Serhan CN
  Nat Immunol. 2006
  PubMed ID: 17013391
   
  
• CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.
  Yurchenko E, Tritt M, Hay V, Shevach EM, Belkaid Y, Piccirillo CA
  J Exp Med. 2006
  PubMed ID: 17015634
   
  
• Resistance profile of a neutralizing anti-HIV monoclonal antibody, KD-247, that shows favourable synergism with anti-CCR5 inhibitors.
  Yoshimura K, Shibata J, Kimura T, Honda A, Maeda Y, Koito A, Murakami T, Mitsuya H, Matsushita S
  AIDS. 2006
  PubMed ID: 17053352
   
  
• Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5.
  Floto RA, MacAry PA, Boname JM, Mien TS, Kampmann B, Hair JR, Huey OS, Houben EN, Pieters J, Day C, Oehlmann W, Singh M, Smith KG, Lehner PJ
  Science. 2006
  PubMed ID: 17053144
   
  
• Blood pressure regulation by CCR genes.
  Mettimano M, Specchia ML, La Torre G, Bruno A, Ricciardi G, Savi L, Romano-Spica V
  Clin Exp Hypertens. 2006
  PubMed ID: 17060059
   
  
• Cytokine and chemokine transcription profile during Mycoplasma pulmonis infection in susceptible and resistant strains of mice: macrophage inflammatory protein 1beta (CCL4) and monocyte chemoattractant protein 2 (CCL8) and accumulation of CCR5+ Th cells.
  Sun X, Jones HP, Hodge LM, Simecka JW
  Infect Immun. 2006
  PubMed ID: 16988274
   
  
• Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia.
  Hunt PW, Harrigan PR, Huang W, Bates M, Williamson DW, McCune JM, Price RW, Spudich SS, Lampiris H, Hoh R, Leigler T, Martin JN, Deeks SG
  J Infect Dis. 2006
  PubMed ID: 16960780
   
  
• Molecular switch for alternative conformations of the HIV-1 V3 region: implications for phenotype conversion.
  Rosen O, Sharon M, Quadt-Akabayov SR, Anglister J
  Proc Natl Acad Sci U S A. 2006
  PubMed ID: 16966601
   
  
• CCR5 expression on monocytes and T cells: modulation by transmigration across the blood-brain barrier in vitro.
  Ubogu EE, Callahan MK, Tucky BH, Ransohoff RM
  Cell Immunol. 2006
  PubMed ID: 17257590
   
  
• Genetic polymorphism of chemokine receptors CCR2 and CCR5 in Swedish cervical cancer patients.
  Zheng B, Wiklund F, Gharizadeh B, Sadat M, Gambelunghe G, Hallmans G, Dillner J, Wallin KL, Ghaderi M
  Anticancer Res. 2006
  PubMed ID: 17094383
   
  
• Association of chemokine receptor 5 (CCR5) delta32 mutation with Behçet's disease is dependent on gender in Iranian patients.
  Mojtahedi Z, Ahmadi SB, Razmkhah M, Azad TK, Rajaee A, Ghaderi A
  Clin Exp Rheumatol. 2006
  PubMed ID: 17067435
   
  
• Gene polymorphisms in CCR5, CCR2, CX3CR1, SDF-1 and RANTES in exposed but uninfected partners of HIV-1 infected individuals in North India.
  Suresh P, Wanchu A, Sachdeva RK, Bhatnagar A
  J Clin Immunol. 2006
  PubMed ID: 16865553
   
  
• CCL5-CCR5-mediated apoptosis in T cells: Requirement for glycosaminoglycan binding and CCL5 aggregation.
  Murooka TT, Wong MM, Rahbar R, Majchrzak-Kita B, Proudfoot AE, Fish EN
  J Biol Chem. 2006
  PubMed ID: 16807236
   
  
• HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein.
  Ronaldson PT, Bendayan R
  Mol Pharmacol. 2006
  PubMed ID: 16790532
   
  
• Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis.
  Prahalad S, Bohnsack JF, Jorde LB, Whiting A, Clifford B, Dunn D, Weiss R, Moroldo M, Thompson SD, Glass DN, Bamshad MJ
  Genes Immun. 2006
  PubMed ID: 16775617
   
  
• Caffeic acid phenethyl ester modifies the Th1/Th2 balance in ileal mucosa after gamma-irradiation in the rat by modulating the cytokine pattern.
  Grémy O, Benderitter M, Linard C
  World J Gastroenterol. 2006
  PubMed ID: 16937495
   
  
• The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages.
  Tomkowicz B, Lee C, Ravyn V, Cheung R, Ptasznik A, Collman RG
  Blood. 2006
  PubMed ID: 16621960
   
  
• CCR5Delta32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C.
  Goyal A, Suneetha PV, Kumar GT, Shukla DK, Arora N, Sarin SK
  World J Gastroenterol. 2006
  PubMed ID: 16937446
   
  
• Effect of T helper 1 (Th1)/Th2 cytokine on chemokine-induced dendritic cell functions.
  Clingan JM, Yanagawa Y, Iwabuchi K, Onoé K
  Cell Immunol. 2006
  PubMed ID: 17098215
   
  
• Gene expression profiling of skin and draining lymph nodes of rats affected with cutaneous contact hypersensitivity.
  Hartmann B, Staedtler F, Hartmann N, Meingassner J, Firat H
  Inflamm Res. 2006
  PubMed ID: 16977379
   
  
• Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
  Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
  Mol Cell. 2006
  PubMed ID: 16916647
   
  
• Historic exposure to plague and present-day frequency of CCR5del32 in two isolated island communities of Dalmatia, Croatia.
  Smoljanović M, Ristić S, Hayward C
  Croat Med J. 2006
  PubMed ID: 16909455
   
  
• Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: impact of chemokines and adhesion molecules.
  Herold S, von Wulffen W, Steinmueller M, Pleschka S, Kuziel WA, Mack M, Srivastava M, Seeger W, Maus UA, Lohmeyer J
  J Immunol. 2006
  PubMed ID: 16849492
   
  
• Human cytomegalovirus modulation of CCR5 expression on myeloid cells affects susceptibility to human immunodeficiency virus type 1 infection.
  King CA, Baillie J, Sinclair JH
  J Gen Virol. 2006
  PubMed ID: 16847113
   
  
• Role of bone marrow-derived CC-chemokine receptor 5 in the development of atherosclerosis of low-density lipoprotein receptor knockout mice.
  Potteaux S, Combadière C, Esposito B, Lecureuil C, Ait-Oufella H, Merval R, Ardouin P, Tedgui A, Mallat Z
  Arterioscler Thromb Vasc Biol. 2006
  PubMed ID: 16763157
   
  
• Functional impact of HIV coreceptor-binding site mutations.
  Biscone MJ, Miamidian JL, Muchiri JM, Baik SS, Lee FH, Doms RW, Reeves JD
  Virology. 2006
  PubMed ID: 16631222
   
  
• The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients.
  Melum E, Karlsen TH, Broomé U, Thorsby E, Schrumpf E, Boberg KM, Lie BA
  Tissue Antigens. 2006
  PubMed ID: 16774544
   
  
• Chemotactic cytokine receptor 5 (CCR5) gene promoter polymorphism (59029A/G) is associated with diabetic nephropathy in Japanese patients with type 2 diabetes: a 10-year longitudinal study.
  Mokubo A, Tanaka Y, Nakajima K, Watada H, Hirose T, Kawasumi M, Sakai K, Kanazawa A, Maeda S, Hosokawa K, Atsumi Y, Matsuoka K, Kawamori R
  Diabetes Res Clin Pract. 2006
  PubMed ID: 16442182
   
  
• CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection.
  Khan IA, Thomas SY, Moretto MM, Lee FS, Islam SA, Combe C, Schwartzman JD, Luster AD
  PLoS Pathog. 2006
  PubMed ID: 16789839
   
  
• No association of CCR5delta32 gene mutation with multiple sclerosis in Croatian and Slovenian patients.
  Ristić S, Lovrecić L, Starcević-Cizmarević N, Brajenović-Milić B, Jazbec SS, Barac-Latas V, Vejnović D, Sepcić J, Kapović M, Peterlin B
  Mult Scler. 2006
  PubMed ID: 16764352
   
  
• CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism.
  Shideman CR, Hu S, Peterson PK, Thayer SA
  J Neurosci Res. 2006
  PubMed ID: 16547971
   
  
• Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness.
  Walker JK, Ahumada A, Frank B, Gaspard R, Berman K, Quackenbush J, Schwartz DA
  Am J Respir Cell Mol Biol. 2006
  PubMed ID: 16474097
   
  
• Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10.
  Zernecke A, Liehn EA, Gao JL, Kuziel WA, Murphy PM, Weber C
  Blood. 2006
  PubMed ID: 16467202
   
  
• Structural and molecular interactions of CCR5 inhibitors with CCR5.
  Maeda K, Das D, Ogata-Aoki H, Nakata H, Miyakawa T, Tojo Y, Norman R, Takaoka Y, Ding J, Arnold GF, Arnold E, Mitsuya H
  J Biol Chem. 2006
  PubMed ID: 16476734
   
  
• Lack of higher frequency of the chemokine receptor 5-delta32/delta32 genotype in hepatitis C.
  Tommasi AM, Fabris P, Carderi I, Baragiotta A, Baldo V, Venturi C, Giordani MT, Tositti G, Floreani A
  J Clin Gastroenterol. 2006
  PubMed ID: 16721228
   
  
• Induction of human immunodeficiency virus neutralizing antibodies using fusion complexes.
  Zipeto D, Matucci A, Ripamonti C, Scarlatti G, Rossolillo P, Turci M, Sartoris S, Tridente G, Bertazzoni U
  Microbes Infect. 2006
  PubMed ID: 16702010
   
  
• Polymorphisms in the genes encoding chemokine receptor 5, interleukin-10, and monocyte chemoattractant protein 1 contribute to cytomegalovirus reactivation and disease after allogeneic stem cell transplantation.
  Loeffler J, Steffens M, Arlt EM, Toliat MR, Mezger M, Suk A, Wienker TF, Hebart H, Nürnberg P, Boeckh M, Ljungman P, Trenschel R, Einsele H
  J Clin Microbiol. 2006
  PubMed ID: 16672419
   
  
• Angiotensin II-induced mononuclear leukocyte interactions with arteriolar and venular endothelium are mediated by the release of different CC chemokines.
  Mateo T, Abu Nabah YN, Abu Taha M, Mata M, Cerdá-Nicolás M, Proudfoot AE, Stahl RA, Issekutz AC, Cortijo J, Morcillo EJ, Jose PJ, Sanz MJ
  J Immunol. 2006
  PubMed ID: 16622027
   
  
• The multiple personalities of the chemokine receptor CCR7 in dendritic cells.
  Sánchez-Sánchez N, Riol-Blanco L, Rodríguez-Fernández JL
  J Immunol. 2006
  PubMed ID: 16621978
   
  
• Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease.
  Suneetha PV, Sarin SK, Goyal A, Kumar GT, Shukla DK, Hissar S
  J Hepatol. 2006
  PubMed ID: 16545485
   
  
• Spatially distinct and functionally independent mechanisms of axonal degeneration in a model of HIV-associated sensory neuropathy.
  Melli G, Keswani SC, Fischer A, Chen W, Höke A
  Brain. 2006
  PubMed ID: 16537566
   
  
• Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women.
  Pai JK, Kraft P, Cannuscio CC, Manson JE, Rexrode KM, Albert CM, Hunter D, Rimm EB
  Atherosclerosis. 2006
  PubMed ID: 16055130
   
  
• The DNA sequence, annotation and analysis of human chromosome 3.
  Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA
  Nature. 2006
  PubMed ID: 16641997
   
  
• Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling.
  Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, Lee CG, Elias JA
  J Immunol. 2006
  PubMed ID: 16585593
   
  
• Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.
  Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN
  Nature. 2006
  PubMed ID: 16612374
   
  
• Genomic organization, expression profile, and characterization of the new protein PRA1 domain family, member 2 (PRAF2).
  Fo CS, Coleman CS, Wallick CJ, Vine AL, Bachmann AS
  Gene. 2006
  PubMed ID: 16481131
   
  
• CC-type chemokine receptor 5-Delta32 mutation protects against primary sclerosing cholangitis.
  Henckaerts L, Fevery J, Van Steenbergen W, Verslype C, Yap P, Nevens F, Roskams T, Libbrecht L, Rutgeerts P, Vermeire S
  Inflamm Bowel Dis. 2006
  PubMed ID: 16633049
   
  
• Inflammation, genetic polymorphisms in proinflammatory genes TNF-A, RANTES, and CCR5, and risk of pancreatic adenocarcinoma.
  Duell EJ, Casella DP, Burk RD, Kelsey KT, Holly EA
  Cancer Epidemiol Biomarkers Prev. 2006
  PubMed ID: 16614115
   
  
• BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
  Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
  PLoS Biol. 2006
  PubMed ID: 16602821
   
  
• Negative association between the chemokine receptor CCR5-Delta32 polymorphism and rheumatoid arthritis: a meta-analysis.
  Prahalad S
  Genes Immun. 2006
  PubMed ID: 16541097
   
  
• Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia.
  Cowell RM, Xu H, Parent JM, Silverstein FS
  J Neuroimmunol. 2006
  PubMed ID: 16516309
   
  
• Maturation of the viral core enhances the fusion of HIV-1 particles with primary human T cells and monocyte-derived macrophages.
  Jiang J, Aiken C
  Virology. 2006
  PubMed ID: 16375941
   
  
• CXCR4 and CCR5 mediate homing of primitive bone marrow-derived hematopoietic cells to the postnatal thymus.
  Robertson P, Means TK, Luster AD, Scadden DT
  Exp Hematol. 2006
  PubMed ID: 16543065
   
  
• Association between the CCR5 32-bp deletion allele and late onset of schizophrenia.
  Rasmussen HB, Timm S, Wang AG, Søeby K, Lublin H, Fenger M, Hemmingsen R, Werge T
  Am J Psychiatry. 2006
  PubMed ID: 16513874
   
  
• No association between selected candidate gene polymorphisms and severe chronic periodontitis.
  Wohlfahrt JC, Wu T, Hodges JS, Hinrichs JE, Michalowicz BS
  J Periodontol. 2006
  PubMed ID: 16512757
   
  
• Frequency of CCR5delta32 in Brazilian populations.
  Vargas AE, Marrero AR, Salzano FM, Bortolini MC, Chies JA
  Braz J Med Biol Res. 2006
  PubMed ID: 16501811
   
  
• CCR5 use by human immunodeficiency virus type 1 is associated closely with the gp120 V3 loop N-linked glycosylation site.
  Clevestig P, Pramanik L, Leitner T, Ehrnst A
  J Gen Virol. 2006
  PubMed ID: 16476981
   
  
• Abnormal immune response of CCR5-deficient mice to ocular infection with herpes simplex virus type 1.
  Carr DJ, Ash J, Lane TE, Kuziel WA
  J Gen Virol. 2006
  PubMed ID: 16476970
   
  
• Involvement of CCR5 in the passage of Th1-type cells across the blood-retina barrier in experimental autoimmune uveitis.
  Crane IJ, Xu H, Wallace C, Manivannan A, Mack M, Liversidge J, Marquez G, Sharp PF, Forrester JV
  J Leukoc Biol. 2006
  PubMed ID: 16365158
   
  
• Chemokine receptor CXCR3 desensitization by IL-16/CD4 signaling is dependent on CCR5 and intact membrane cholesterol.
  Rahangdale S, Morgan R, Heijens C, Ryan TC, Yamasaki H, Bentley E, Sullivan E, Center DM, Cruikshank WW
  J Immunol. 2006
  PubMed ID: 16455991
   
  
• Polymorphisms in chemokine and chemokine receptor genes and the development of coal workers' pneumoconiosis.
  Nadif R, Mintz M, Rivas-Fuentes S, Jedlicka A, Lavergne E, Rodero M, Kauffmann F, Combadière C, Kleeberger SR
  Cytokine. 2006
  PubMed ID: 16524739
   
  
• Analysis of CCR5, CCR2, CX3CR1, and SDF1 polymorphisms in HIV-positive treated patients: impact on response to HAART and on peripheral T lymphocyte counts.
  Puissant B, Roubinet F, Massip P, Sandres-Saune K, Apoil PA, Abbal M, Pasquier C, Izopet J, Blancher A
  AIDS Res Hum Retroviruses. 2006
  PubMed ID: 16478397
   
  
• CC-chemokine receptor five gene polymorphism in primary IgA nephropathy: the 32 bp deletion allele is associated with late progression to end-stage renal failure with dialysis.
  Berthoux FC, Berthoux P, Mariat C, Thibaudin L, Afiani A, Linossier MT
  Kidney Int. 2006
  PubMed ID: 16395252
   
  
• Real-time analysis of human immunodeficiency virus type 1 Env-mediated membrane fusion by fluorescence resonance energy transfer.
  Furuta RA, Nishikawa M, Fujisawa J
  Microbes Infect. 2006
  PubMed ID: 16300985
   
  
• CCR5 promoter polymorphisms and HIV-1 perinatal transmission in Brazilian children.
  de Souza PR, Arraes LC, de Lima Filho JL, Bruneska D, Milanese M, Crovella S
  J Reprod Immunol. 2006
  PubMed ID: 16233918
   
  
• Expression of CCL5 (RANTES) and CCR5 in prostate cancer.
  Vaday GG, Peehl DM, Kadam PA, Lawrence DM
  Prostate. 2006
  PubMed ID: 16161154
   
  
• CCR5 deficiency increases risk of symptomatic West Nile virus infection.
  Glass WG, McDermott DH, Lim JK, Lekhong S, Yu SF, Frank WA, Pape J, Cheshier RC, Murphy PM
  J Exp Med. 2006
  PubMed ID: 16418398
   
  
• The role of T helper cell subsets in pathogenesis of Systemic Lupus Erythematosus and their relation to disease activity.
  Al-Saleh J, el-Eissawy S
  Egypt J Immunol. 2006
  PubMed ID: 18689270
   
  
• Effects of polymorphisms of chemokine receptors on neurodevelopment and the onset of encephalopathy in children with perinatal HIV-1 infection.
  Llorente A, Brouwers P, Thompson B, Cheng I, Macmillan C, Larussa P, Mofenson L, Blasini I, Chase C
  Appl Neuropsychol. 2006
  PubMed ID: 17361671
   
  
• Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model.
  Menu E, De Leenheer E, De Raeve H, Coulton L, Imanishi T, Miyashita K, Van Valckenborgh E, Van Riet I, Van Camp B, Horuk R, Croucher P, Vanderkerken K
  Clin Exp Metastasis. 2006
  PubMed ID: 17086356
   
  
• Partial protective effect of CCR5-Delta 32 heterozygosity in a cohort of heterosexual Italian HIV-1 exposed uninfected individuals.
  Trecarichi EM, Tumbarello M, de Gaetano Donati K, Tamburrini E, Cauda R, Brahe C, Tiziano FD
  AIDS Res Ther. 2006
  PubMed ID: 16999868
   
  
• Three allele combinations associated with multiple sclerosis.
  Favorova OO, Favorov AV, Boiko AN, Andreewski TV, Sudomoina MA, Alekseenkov AD, Kulakova OG, Gusev EI, Parmigiani G, Ochs MF
  BMC Med Genet. 2006
  PubMed ID: 16872485
   
  
• Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.
  Binley JM, Ngo-Abdalla S, Moore P, Bobardt M, Chatterji U, Gallay P, Burton DR, Wilson IA, Elder JH, de Parseval A
  Retrovirology. 2006
  PubMed ID: 16817962
   
  
• Impact of CCR5 Delta32/+ deletion on herpes zoster among HIV-1-infected homosexual men.
  Krol A, Lensen R, Veenstra J, Prins M, Schuitemaker H, Coutinho RA
  Eur J Epidemiol. 2006
  PubMed ID: 16703416
   
  
• Oral mucosal expression of HIV-1 receptors, co-receptors, and alpha-defensins: tableau of resistance or susceptibility to HIV infection?
  Cutler CW, Jotwani R
  Adv Dent Res. 2006
  PubMed ID: 16672549
   
  
• Genetic variations in CC chemokine receptors and hypertension.
  Zhang M, Ardlie K, Wacholder S, Welch R, Chanock S, O'Brien TR
  Am J Hypertens. 2006
  PubMed ID: 16461193
   
  
• Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations.
  Pastore C, Nedellec R, Ramos A, Pontow S, Ratner L, Mosier DE
  J Virol. 2006
  PubMed ID: 16378977
   
  
• Induction of RANTES and CCR5 through NF-kappaB activation via MAPK pathway in aged rat gingival tissues.
  Kim HK, Park HR, Sul KH, Chung HY, Chung J
  Biotechnol Lett. 2006
  PubMed ID: 16369869
   
  
• The CC chemokine receptor 5 is important in control of parasite replication and acute cardiac inflammation following infection with Trypanosoma cruzi.
  Hardison JL, Wrightsman RA, Carpenter PM, Kuziel WA, Lane TE, Manning JE
  Infect Immun. 2006
  PubMed ID: 16368966
   
  
• Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
  Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
  Genome Res. 2006
  PubMed ID: 16344560
   
  
• Behavioral risk exposure and host genetics of susceptibility to HIV-1 infection.
  Shrestha S, Strathdee SA, Galai N, Oleksyk T, Fallin MD, Mehta S, Schaid D, Vlahov D, O'Brien SJ, Smith MW
  J Infect Dis. 2006
  PubMed ID: 16323127
   
  
• Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue.
  Reichel CA, Khandoga A, Anders HJ, Schlöndorff D, Luckow B, Krombach F
  J Leukoc Biol. 2006
  PubMed ID: 16275892
   
  
• Spanish HIV-1-infected long-term nonprogressors of more than 15 years have an increased frequency of the CX3CR1 249I variant allele.
  Vidal F, Viladés C, Domingo P, Broch M, Pedrol E, Dalmau D, Knobel H, Peraire J, Gutiérrez C, Sambeat MA, Fontanet A, Deig E, Cairó M, Montero M, Richart C, Mallal S, Chemokines LTNP Study Group
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 16284527
   
  
• Short communication: Influence of active tuberculosis on chemokine and chemokine receptor expression in HIV-infected persons.
  Hanna LE, Bose JC, Nayak K, Subramanyam S, Swaminathan S
  AIDS Res Hum Retroviruses. 2005
  PubMed ID: 16379602
   
  
• Chemokine receptor expression in rat adjuvant-induced arthritis.
  Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE
  Arthritis Rheum. 2005
  PubMed ID: 16320322
   
  
• Polymorphisms of chemokine receptors and eNOS in Brazilian patients with sickle cell disease.
  Vargas AE, da Silva MA, Silla L, Chies JA
  Tissue Antigens. 2005
  PubMed ID: 16305685
   
  
• Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population.
  Apostolakis S, Baritaki S, Krambovitis E, Spandidos DA
  J Clin Virol. 2005
  PubMed ID: 16286055
   
  
• Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema.
  Ma B, Kang MJ, Lee CG, Chapoval S, Liu W, Chen Q, Coyle AJ, Lora JM, Picarella D, Homer RJ, Elias JA
  J Clin Invest. 2005
  PubMed ID: 16284650
   
  
• CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis.
  Kantarci OH, Morales Y, Ziemer PA, Hebrink DD, Mahad DJ, Atkinson EJ, Achenbach SJ, De Andrade M, Mack M, Ransohoff RM, Lassmann H, Bruck W, Weinshenker BG, Lucchinetti CF
  J Neuroimmunol. 2005
  PubMed ID: 16182378
   
  
• Beta-chemokine receptors 5 and 3 are expressed on the head region of human spermatozoon.
  Muciaccia B, Padula F, Vicini E, Gandini L, Lenzi A, Stefanini M
  FASEB J. 2005
  PubMed ID: 16174786
   
  
• [Single nucleotide polymorphisms of HIV coreceptor CCR5 gene in Chinese Yi ethnic group and its association with HIV infection]
  Ma LY, Hong KX, Lu XZ, Qin GM, Chen JP, Chen KL, Ruan YH, Xing H, Zhu JH, Shao YM
  Zhonghua Yi Xue Za Zhi. 2005
  PubMed ID: 16405836
   
  
• Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol.
  Blednov YA, Bergeson SE, Walker D, Ferreira VM, Kuziel WA, Harris RA
  Behav Brain Res. 2005
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• Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy.
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• A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs.
  de Parseval A, Bobardt MD, Chatterji A, Chatterji U, Elder JH, David G, Zolla-Pazner S, Farzan M, Lee TH, Gallay PA
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• CCR5, RANTES and CX3CR1 polymorphisms: possible genetic links with acute heart rejection.
  Simeoni E, Vassalli G, Seydoux C, Ramsay D, Noll G, von Segesser LK, Fleury S
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• G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers.
  Hüttenrauch F, Pollok-Kopp B, Oppermann M
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• [Comparison CCR5de132 mutation in the CCR5 gene frequencies in Russians, Tuvinians, and in different groups of HIV-infected individuals]
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• Lack of association of SDF-1 3'A variant allele with long-term nonprogressive HIV-1 infection is extended beyond 16 years.
  Vidal F, Peraire J, Domingo P, Broch M, Knobel H, Pedrol E, Dalmau D, Viladés C, Sambeat MA, Gutiérrez C, Richart C, Chemokines and Long-Term Nonprogressor Study Group
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• The case for selection at CCR5-Delta32.
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• CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection.
  Tyner JW, Uchida O, Kajiwara N, Kim EY, Patel AC, O'Sullivan MP, Walter MJ, Schwendener RA, Cook DN, Danoff TM, Holtzman MJ
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• Stromal cell-derived factor-1 genotype, coreceptor tropism, and HIV type 1 disease progression.
  Daar ES, Lynn HS, Donfield SM, Lail A, O'Brien SJ, Huang W, Winkler CA, Hemophilia Growth and Development Study
  J Infect Dis. 2005
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• Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
  Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, Taylor PA, McKinnon KP, Su L, Blazar BR, Serody JS
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• Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection.
  Glass WG, Lim JK, Cholera R, Pletnev AG, Gao JL, Murphy PM
  J Exp Med. 2005
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• Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma.
  Musha H, Ohtani H, Mizoi T, Kinouchi M, Nakayama T, Shiiba K, Miyagawa K, Nagura H, Yoshie O, Sasaki I
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• CCR5-deficient mice develop experimental autoimmune uveoretinitis in the context of a deviant effector response.
  Takeuchi A, Usui Y, Takeuchi M, Hattori T, Kezuka T, Suzuki J, Okunuki Y, Iwasaki T, Haino M, Matsushima K, Usui M
  Invest Ophthalmol Vis Sci. 2005
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• The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells.
  Mondal D, Williams CA, Ali M, Eilers M, Agrawal KC
  Exp Biol Med (Maywood). 2005
  PubMed ID: 16179731
   
  
• CCR5 deficiency exacerbates T-cell-mediated hepatitis in mice.
  Moreno C, Gustot T, Nicaise C, Quertinmont E, Nagy N, Parmentier M, Le Moine O, Devière J, Louis H
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• Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.
  Dong HF, Wigmore K, Carrington MN, Dean M, Turpin JA, Howard OM
  Genes Immun. 2005
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• C-C chemokine receptor 5 gene variants in relation to lung disease in sarcoidosis.
  Spagnolo P, Renzoni EA, Wells AU, Copley SJ, Desai SR, Sato H, Grutters JC, Abdallah A, Taegtmeyer A, du Bois RM, Welsh KI
  Am J Respir Crit Care Med. 2005
  PubMed ID: 15976369
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
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• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• [Effect of CCR5delta32, CCR5m303, CCR2-64I and SDF1-3'A gene polymorphism on the prognosis of Chinese HIV-1 carriers]
  Wang XH, Feng TJ, Wang FS, Chen L, Shi XD, Jin L
  Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2005
  PubMed ID: 16261210
   
  
• Combined effect of CCR5-Delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission.
  Hladik F, Liu H, Speelmon E, Livingston-Rosanoff D, Wilson S, Sakchalathorn P, Hwangbo Y, Greene B, Zhu T, McElrath MJ
  J Virol. 2005
  PubMed ID: 16140745
   
  
• A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.
  Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM
  Neuron. 2005
  PubMed ID: 16129397
   
  
• Isolation of TAK-779-resistant HIV-1 from an R5 HIV-1 GP120 V3 loop library.
  Yusa K, Maeda Y, Fujioka A, Monde K, Harada S
  J Biol Chem. 2005
  PubMed ID: 15983047
   
  
• Use of alternate coreceptors on primary cells by two HIV-1 isolates.
  Cilliers T, Willey S, Sullivan WM, Patience T, Pugach P, Coetzer M, Papathanasopoulos M, Moore JP, Trkola A, Clapham P, Morris L
  Virology. 2005
  PubMed ID: 15992849
   
  
• CCR5delta32, CCR2-64I, and SDF1-3'A polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population.
  Paz-y-Mino C, Morillo SA, Celi AP, Witte T, Muñoz Guijarro MJ, Collantes JC, Leone PE
  Hum Biol. 2005
  PubMed ID: 16485782
   
  
• The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients.
  Mikawa AY, Malavazi I, Tagliavini SA, Abrão EP, da Costa PI
  Braz J Infect Dis. 2005
  PubMed ID: 16270124
   
  
• Host inflammatory response and development of complications of Chlamydia trachomatis genital infection in CCR5-deficient mice and subfertile women with the CCR5delta32 gene deletion.
  Barr EL, Ouburg S, Igietseme JU, Morré SA, Okwandu E, Eko FO, Ifere G, Belay T, He Q, Lyn D, Nwankwo G, Lillard J, Black CM, Ananaba GA
  J Microbiol Immunol Infect. 2005
  PubMed ID: 16118671
   
  
• Frequency of CCR5 gene 32-basepair deletion in Croatian normal population.
  Ristić S, Starcević Cizmarević N, Brajenović-Milić B, Crnić-Martinović M, Kapović M
  Croat Med J. 2005
  PubMed ID: 16100775
   
  
• Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice.
  de Lemos C, Christensen JE, Nansen A, Moos T, Lu B, Gerard C, Christensen JP, Thomsen AR
  J Immunol. 2005
  PubMed ID: 16034118
   
  
• Age-dependent role for CCR5 in antiviral host defense against herpes simplex virus type 2.
  Ank N, Petersen K, Malmgaard L, Mogensen SC, Paludan SR
  J Virol. 2005
  PubMed ID: 16014944
   
  
• The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source.
  Goulding C, McManus R, Murphy A, MacDonald G, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D
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  PubMed ID: 15863470
   
  
• Chemokine receptor CCR7 is expressed in muscle fibers in juvenile dermatomyositis.
  Minetti C, Gattorno M, Repetto S, Gregorio A, Pedemonte M, Assereto S, Zara F, Bruno C, Martini A
  Biochem Biophys Res Commun. 2005
  PubMed ID: 15950936
   
  
• Migration of perilesional microglia after focal brain injury and modulation by CC chemokine receptor 5: an in situ time-lapse confocal imaging study.
  Carbonell WS, Murase S, Horwitz AF, Mandell JW
  J Neurosci. 2005
  PubMed ID: 16049180
   
  
• Restricted variable residues in the C-terminal segment of HIV-1 V3 loop regulate the molecular anatomy of CCR5 utilization.
  Hu Q, Napier KB, Trent JO, Wang Z, Taylor S, Griffin GE, Peiper SC, Shattock RJ
  J Mol Biol. 2005
  PubMed ID: 15964018
   
  
• Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.
  Burns JC, Shimizu C, Gonzalez E, Kulkarni H, Patel S, Shike H, Sundel RS, Newburger JW, Ahuja SK
  J Infect Dis. 2005
  PubMed ID: 15962231
   
  
• Decreased IgG production but increased MIP-1beta expression in collagen-induced arthritis in C-C chemokine receptor 5-deficient mice.
  Bao L, Zhu Y, Zhu J, Lindgren JU
  Cytokine. 2005
  PubMed ID: 15967376
   
  
• Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome.
  Gray L, Sterjovski J, Churchill M, Ellery P, Nasr N, Lewin SR, Crowe SM, Wesselingh SL, Cunningham AL, Gorry PR
  Virology. 2005
  PubMed ID: 15916792
   
  
• T-cell and chemokine receptor variation in south Amerindian populations.
  Hünemeier T, Neves AG, Nornberg I, Hill K, Hurtado AM, Carnese FR, Goicoechea AS, Hutz MH, Salzano FM, Chies JA
  Am J Hum Biol. 2005
  PubMed ID: 15981170
   
  
• Causal pathways of the effects of age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on AIDS development.
  Geskus RB, Meyer L, Hubert JB, Schuitemaker H, Berkhout B, Rouzioux C, Theodorou ID, Delfraissy JF, Prins M, Coutinho RA
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15980693
   
  
• HIV type 1 glycoprotein 120 inhibits human B cell chemotaxis to CXC chemokine ligand (CXCL) 12, CC chemokine ligand (CCL)20, and CCL21.
  Badr G, Borhis G, Treton D, Moog C, Garraud O, Richard Y
  J Immunol. 2005
  PubMed ID: 15972662
   
  
• Genotypes at chromosome 22q12-13 are associated with HIV-1-exposed but uninfected status in Italians.
  Kanari Y, Clerici M, Abe H, Kawabata H, Trabattoni D, Caputo SL, Mazzotta F, Fujisawa H, Niwa A, Ishihara C, Takei YA, Miyazawa M
  AIDS. 2005
  PubMed ID: 15958832
   
  
• Significance of chemokine receptor expression in aggressive NK cell leukemia.
  Makishima H, Ito T, Asano N, Nakazawa H, Shimodaira S, Kamijo Y, Nakazawa Y, Suzuki T, Kobayashi H, Kiyosawa K, Ishida F
  Leukemia. 2005
  PubMed ID: 15902300
   
  
• MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4.
  Ramos CD, Canetti C, Souto JT, Silva JS, Hogaboam CM, Ferreira SH, Cunha FQ
  J Leukoc Biol. 2005
  PubMed ID: 15831559
   
  
• Role of Rho family GTPases in CCR1- and CCR5-induced actin reorganization in macrophages.
  Di Marzio P, Dai WW, Franchin G, Chan AY, Symons M, Sherry B
  Biochem Biophys Res Commun. 2005
  PubMed ID: 15882964
   
  
• The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.
  Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX
  J Immunol. 2005
  PubMed ID: 15944326
   
  
• Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells.
  Ajuebor MN, Aspinall AI, Zhou F, Le T, Yang Y, Urbanski SJ, Sidobre S, Kronenberg M, Hogaboam CM, Swain MG
  J Immunol. 2005
  PubMed ID: 15944310
   
  
• [Mystery upon the origin for the selection of AIDS-protective CCR5Delta32]
  Janvier S, Heveker N
  Med Sci (Paris). 2005
  PubMed ID: 15985194
   
  
• [Association between CCR5 promoter polymorphisms and hepatitis B virus infection]
  Chang HY, Ahn SH, Kim DY, Shin JS, Kim YS, Hong SP, Chung HJ, Kim SO, Yoo WD, Han KH
  Korean J Hepatol. 2005
  PubMed ID: 15980670
   
  
• Donor CCR5 Delta32 polymorphism and outcome following cardiac transplantation.
  Fildes JE, Walker AH, Howlett R, Bittar MN, Hutchinson IV, Leonard CT, Yonan N
  Transplant Proc. 2005
  PubMed ID: 15964389
   
  
• Distribution of the mutated delta 32 allele of the CCR5 gene in a Sicilian population.
  Sidoti A, D'Angelo R, Rinaldi C, De Luca G, Pino F, Salpietro C, Giunta DE, Saltalamacchia F, Amato A
  Int J Immunogenet. 2005
  PubMed ID: 15932625
   
  
• CC chemokine receptor 5 (CCR5) deletion polymorphism does not protect Czech males against early myocardial infarction.
  Petrkova J, Cermakova Z, Lukl J, Petrek M
  J Intern Med. 2005
  PubMed ID: 15910562
   
  
• Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using, primary human immunodeficiency virus type 1 strains.
  Lusso P, Earl PL, Sironi F, Santoro F, Ripamonti C, Scarlatti G, Longhi R, Berger EA, Burastero SE
  J Virol. 2005
  PubMed ID: 15890935
   
  
• Increased expression of CXCR3 and CCR5 on memory CD4+ T-cells migrating into the cerebrospinal fluid of patients with neuroborreliosis: the role of CXCL10 and CXCL11.
  Lepej SZ, Rode OD, Jeren T, Vince A, Remenar A, Barsić B
  J Neuroimmunol. 2005
  PubMed ID: 15885315
   
  
• Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2.
  Abonia JP, Austen KF, Rollins BJ, Joshi SK, Flavell RA, Kuziel WA, Koni PA, Gurish MF
  Blood. 2005
  PubMed ID: 15705791
   
  
• Absence of recipient CCR5 promotes early and increased allospecific antibody responses to cardiac allografts.
  Amano H, Bickerstaff A, Orosz CG, Novick AC, Toma H, Fairchild RL
  J Immunol. 2005
  PubMed ID: 15879153
   
  
• Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.
  Xiang SH, Farzan M, Si Z, Madani N, Wang L, Rosenberg E, Robinson J, Sodroski J
  J Virol. 2005
  PubMed ID: 15857992
   
  
• Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 Variant in China's Sichuan population.
  Ma L, Dudoit Y, Tran T, Xing H, Chen J, Pancino G, Bismuth G, Debré P, Shao Y, Theodorou I, Capoulade-Métay C
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15851912
   
  
• Gene therapy to manipulate effector T cell trafficking to tumors for immunotherapy.
  Gough M, Crittenden M, Thanarajasingam U, Sanchez-Perez L, Thompson J, Jevremovic D, Vile R
  J Immunol. 2005
  PubMed ID: 15843579
   
  
• Post-reperfusion changes of monocyte function in coronary blood after extracorporeal circulation.
  Sbrana S, Bevilacqua S, Buffa M, Spiller D, Parri MS, Gianetti J, De Filippis R, Clerico A
  Cytometry B Clin Cytom. 2005
  PubMed ID: 15786508
   
  
• The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.
  Michel N, Allespach I, Venzke S, Fackler OT, Keppler OT
  Curr Biol. 2005
  PubMed ID: 15854903
   
  
• C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis.
  van Deventer HW, O'Connor W, Brickey WJ, Aris RM, Ting JP, Serody JS
  Cancer Res. 2005
  PubMed ID: 15833871
   
  
• The effect of RANTES chemokine genetic variants on early HIV-1 plasma RNA among African American injection drug users.
  Duggal P, Winkler CA, An P, Yu XF, Farzadegan H, O'Brien SJ, Beaty TH, Vlahov D
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15793370
   
  
• Functional analysis of naturally occurring mutations in the open reading frame of CCR5 in HIV-infected Chinese patients and healthy controls.
  Zhao XY, Lee SS, Wong KH, Chan KC, Ng F, Chan CC, Han D, Yam WC, Yuen KY, Ng MH, Zheng BJ
  J Acquir Immune Defic Syndr. 2005
  PubMed ID: 15793360
   
  
• p38 MAPK-dependent and YY1-mediated chemokine receptors CCR5 and CXCR4 up-regulation in U937 cell line infected by Mycobacterium tuberculosis or Actinobacillus actinomycetemcomitans.
  Lei J, Wu C, Wang X, Wang H
  Biochem Biophys Res Commun. 2005
  PubMed ID: 15737629
   
  
• CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis.
  Capelli A, Di Stefano A, Gnemmi I, Donner CF
  Eur Respir J. 2005
  PubMed ID: 15802346
   
  
• Effects of the NF-kappaB inhibitor pyrrolidine dithiocarbamate on experimentally induced autoimmune anterior uveitis.
  Yang CH, Fang IM, Lin CP, Yang CM, Chen MS
  Invest Ophthalmol Vis Sci. 2005
  PubMed ID: 15790900
   
  
• CCR5 chemokine receptor mediates recruitment of MHC class II-positive Langerhans cells in the mouse corneal epithelium.
  Yamagami S, Hamrah P, Miyamoto K, Miyazaki D, Dekaris I, Dawson T, Lu B, Gerard C, Dana MR
  Invest Ophthalmol Vis Sci. 2005
  PubMed ID: 15790880
   
  
• Distribution of human chemokine (C-X3-C) receptor 1 (CX3CR1) gene polymorphisms and haplotypes of the CC chemokine receptor 5 (CCR5) promoter in Chinese people, and the effects of CCR5 haplotypes on CCR5 expression.
  Li C, Lu SC, Hsieh PS, Huang YH, Huang HI, Ying TH, Shieh B
  Int J Immunogenet. 2005
  PubMed ID: 15787642
   
  
• Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan.
  Platt EJ, Shea DM, Rose PP, Kabat D
  J Virol. 2005
  PubMed ID: 15767436
   
  
• Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus.
  Platt EJ, Durnin JP, Kabat D
  J Virol. 2005
  PubMed ID: 15767435
   
  
• Donor T-cell production of RANTES significantly contributes to the development of idiopathic pneumonia syndrome after allogeneic stem cell transplantation.
  Hildebrandt GC, Olkiewicz KM, Choi S, Corrion LA, Clouthier SG, Liu C, Serody JS, Cooke KR
  Blood. 2005
  PubMed ID: 15546955
   
  
• JM4 is a four-transmembrane protein binding to the CCR5 receptor.
  Schweneker M, Bachmann AS, Moelling K
  FEBS Lett. 2005
  PubMed ID: 15757671
   
  
• MIP-1alpha utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells.
  Oba Y, Lee JW, Ehrlich LA, Chung HY, Jelinek DF, Callander NS, Horuk R, Choi SJ, Roodman GD
  Exp Hematol. 2005
  PubMed ID: 15730850
   
  
• CXCR3, IP-10, and Mig are required for CD4+ T cell recruitment during the DTH response to HSV-1 yet are independent of the mechanism for viral clearance.
  Molesworth-Kenyon S, Mates A, Yin R, Strieter R, Oakes J, Lausch R
  Virology. 2005
  PubMed ID: 15708587
   
  
• The delta32 allele distribution of the CCR5 gene and its relationship with certain cancers in a Turkish population.
  Degerli N, Yilmaz E, Bardakci F
  Clin Biochem. 2005
  PubMed ID: 15708547
   
  
• Evidence for negative association of the chemokine receptor CCR5 d32 polymorphism with rheumatoid arthritis.
  Pokorny V, McQueen F, Yeoman S, Merriman M, Merriman A, Harrison A, Highton J, McLean L
  Ann Rheum Dis. 2005
  PubMed ID: 15331395
   
  
• CCR5 plays a critical role in the development of myocarditis and host protection in mice infected with Trypanosoma cruzi.
  Machado FS, Koyama NS, Carregaro V, Ferreira BR, Milanezi CM, Teixeira MM, Rossi MA, Silva JS
  J Infect Dis. 2005
  PubMed ID: 15655788
   
  
• Association of CCR5 human haplogroup E with rapid HIV type 1 disease progression.
  Li M, Song R, Masciotra S, Soriano V, Spira TJ, Lal RB, Yang C
  AIDS Res Hum Retroviruses. 2005
  PubMed ID: 15725749
   
  
• CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.
  Blaak H, Boers PH, Gruters RA, Schuitemaker H, van der Ende ME, Osterhaus AD
  J Virol. 2005
  PubMed ID: 15650194
   
  
• The frequency of CCR5Delta32 and CCR2-64I in southern Iranian normal population.
  Gharagozloo M, Doroudchi M, Farjadian S, Pezeshki AM, Ghaderi A
  Immunol Lett. 2005
  PubMed ID: 15585333
   
  
• [Effects of CCR5-delta32, CCR2-64I and SDF-1-3'A polymorphic alleles on human immunodeficiency virus 1 (HIV-1) infection in the Polish population]
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• Short communication. Association of the CCR5delta32 mutation with clinical response and >5-year survival following initiation of first triple antiretroviral regimen.
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• Lack of association of CCR gene polymorphisms and left ventricular hypertrophy in essential hypertension.
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  Br J Biomed Sci. 2005
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• Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease.
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  Neuroscience. 2005
  PubMed ID: 15979806
   
  
• 32-nucleotide deletion, associated with defence against hiv/aids, is a predominant mutation of CCR5 gene in the population of Georgia.
  Kamkamidze G, Capoulade-Metay C, Butsashvili M, Dudoit Y, Chubinishvili O, Debre P, Theodorou L
  Georgian Med News. 2005
  PubMed ID: 15821335
   
  
• Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction.
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  Retrovirology. 2005
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• Frequency of the CCR5-Delta32 mutant allele is not increased in Belgian hepatitis C virus-infected patients.
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  Viral Immunol. 2005
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• [The fusion construction of HIV-1 Tat gene and efficient expression in E.coli]
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  Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2005
  PubMed ID: 15629079
   
  
• The chemokine receptor 5 Delta32 mutation is associated with increased renal survival in patients with IgA nephropathy.
  Panzer U, Schneider A, Steinmetz OM, Wenzel U, Barth P, Reinking R, Becker JU, Harendza S, Zahner G, Fischereder M, Krämer BK, Krämer BH, Schlöndorff D, Ostendorf T, Floege J, Helmchen U, Stahl RA
  Kidney Int. 2005
  PubMed ID: 15610230
   
  
• R5 human immunodeficiency virus type 1 infection of fetal thymic organ culture induces cytokine and CCR5 expression.
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  J Virol. 2005
  PubMed ID: 15596839
   
  
• Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
  Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ
  Nat Biotechnol. 2005
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• [Genetic polymorphism of human immunodeficiency virus coreceptor CCR5Delta32 and CCR2-64I alleles in Chinese Yi Ethnic group in Sichuan]
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  Zhonghua Liu Xing Bing Xue Za Zhi. 2004
  PubMed ID: 15769362
   
  
• Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression.
  Winkler CA, Hendel H, Carrington M, Smith MW, Nelson GW, O'brien SJ, Phair J, Vlahov D, Jacobson LP, Rappaport J, Vasilescu A, Bertin-Maghit S, An P, Lu W, Andrieu JM, Schächter F, Therwath A, Zagury JF
  J Acquir Immune Defic Syndr. 2004
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• Chemokine receptor 5 and primary biliary cirrhosis: a two-centre genetic association study.
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  Liver Int. 2004
  PubMed ID: 15566517
   
  
• The CCR5Delta32 allele is associated with reduced liver inflammation in hepatitis C virus infection.
  Wald O, Pappo O, Ari ZB, Azzaria E, Wiess ID, Gafnovitch I, Wald H, Spengler U, Galun E, Peled A
  Eur J Immunogenet. 2004
  PubMed ID: 15548261
   
  
• Role of C-C chemokine receptors 1 and 5 and CCL3/macrophage inflammatory protein-1alpha in the cutaneous Arthus reaction: possible attenuation of their inhibitory effects by compensatory chemokine production.
  Yanaba K, Mukaida N, Matsushima K, Murphy PM, Takehara K, Sato S
  Eur J Immunol. 2004
  PubMed ID: 15517609
   
  
• New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia.
  Capoulade-Métay C, Ma L, Truong LX, Dudoit Y, Versmisse P, Nguyen NV, Nguyen M, Scott-Algara D, Barré-Sinoussi F, Debré P, Bismuth G, Pancino G, Theodorou I
  AIDS. 2004
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• Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease.
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  Neurosci Lett. 2004
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• Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4.
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  J Cell Biochem. 2004
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• Molecular characterization of CCR6: involvement of multiple domains in ligand binding and receptor signaling.
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  J Biomed Sci. 2004
  PubMed ID: 15591779
   
  
• The density of coreceptors at the surface of CD4+ T cells contributes to the extent of human immunodeficiency virus type 1 viral replication-mediated T cell death.
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  AIDS Res Hum Retroviruses. 2004
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• [Effect of HIV Tat protein on CCR5 expression in monocytes and infection with monocyte-tropic HIV strains]
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  Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004
  PubMed ID: 15586413
   
  
• Genetic risk factor characterizes abdominal aortic aneurysm from arterial occlusive disease in human beings: CCR5 Delta 32 deletion.
  Ghilardi G, Biondi ML, Battaglioli L, Zambon A, Guagnellini E, Scorza R
  J Vasc Surg. 2004
  PubMed ID: 15557916
   
  
• Abnormal expression of chemokine receptors in Behçet's disease: relationship to intracellular Th1/Th2 cytokines and to clinical manifestations.
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  J Autoimmun. 2004
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• Binding of HCV E2 to CD81 induces RANTES secretion and internalization of CC chemokine receptor 5.
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  J Viral Hepat. 2004
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• Infection of specific dendritic cells by CCR5-tropic human immunodeficiency virus type 1 promotes cell-mediated transmission of virus resistant to broadly neutralizing antibodies.
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  J Virol. 2004
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• CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease.
  Galimberti D, Fenoglio C, Lovati C, Gatti A, Guidi I, Venturelli E, Cutter GR, Mariani C, Forloni G, Pettenati C, Baron P, Conti G, Bresolin N, Scarpini E
  J Neurol Sci. 2004
  PubMed ID: 15465089
   
  
• [Distribution of the HIV-1 resistance-conferring alleles (CCR5delta32, CCR2-64I, and SDF1 3'A) in Russian, Ukrainian, and Belarusian populations]
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  Genetika. 2004
  PubMed ID: 15575507
   
  
• An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema.
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  PLoS Med. 2004
  PubMed ID: 15526056
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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  Genome Res. 2004
  PubMed ID: 15489334
   
  
• Impaired lung dendritic cell activation in CCR2 knockout mice.
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  Am J Pathol. 2004
  PubMed ID: 15466386
   
  
• Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy.
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  Kidney Int. 2004
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• Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men.
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  J Acquir Immune Defic Syndr. 2004
  PubMed ID: 15385740
   
  
• R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism.
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  J Leukoc Biol. 2004
  PubMed ID: 15258189
   
  
• Analysis of genetic polymorphisms in CCR5, CCR2, stromal cell-derived factor-1, RANTES, and dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin in seronegative individuals repeatedly exposed to HIV-1.
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  J Infect Dis. 2004
  PubMed ID: 15319853
   
  
• CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration.
  Algood HM, Flynn JL
  J Immunol. 2004
  PubMed ID: 15322191
   
  
• A novel assay to identify entry inhibitors that block binding of HIV-1 gp120 to CCR5.
  Zhao Q, He Y, Alespeiti G, Debnath AK
  Virology. 2004
  PubMed ID: 15321703
   
  
• Mobility of the human immunodeficiency virus (HIV) receptor CD4 and coreceptor CCR5 in living cells: implications for HIV fusion and entry events.
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  J Virol. 2004
  PubMed ID: 15308751
   
  
• Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice.
  Luckow B, Joergensen J, Chilla S, Li JP, Henger A, Kiss E, Wieczorek G, Roth L, Hartmann N, Hoffmann R, Kretzler M, Nelson PJ, Pérez de Lema G, Maier H, Wurst W, Balling R, Pfeffer K, Gröne HJ, Schlöndorff D, Zerwes HG
  Eur J Immunol. 2004
  PubMed ID: 15307189
   
  
• CCR5-Delta32 mutation is strongly associated with primary sclerosing cholangitis.
  Eri R, Jonsson JR, Pandeya N, Purdie DM, Clouston AD, Martin N, Duffy D, Powell EE, Fawcett J, Florin TH, Radford-Smith GL
  Genes Immun. 2004
  PubMed ID: 15215889
   
  
• I-TAC/CXCL11 is a natural antagonist for CCR5.
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  J Leukoc Biol. 2004
  PubMed ID: 15178708
   
  
• A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor.
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  AIDS. 2004
  PubMed ID: 15280786
   
  
• The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer's disease.
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  Neurosci Lett. 2004
  PubMed ID: 15288441
   
  
• Distribution of CCR5-delta32, CCR2-64I, and SDF1-3'A mutations in populations from the Brazilian Amazon region.
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  Hum Biol. 2004
  PubMed ID: 15754978
   
  
• Association of RANTES G-403A gene polymorphism with increased risk of coronary arteriosclerosis.
  Simeoni E, Winkelmann BR, Hoffmann MM, Fleury S, Ruiz J, Kappenberger L, März W, Vassalli G
  Eur Heart J. 2004
  PubMed ID: 15302103
   
  
• CCR5 deficiency does not prevent P0 peptide 180-199 immunized mice from experimental autoimmune neuritis.
  Duan RS, Chen Z, Bao L, Quezada HC, Nennesmo I, Winblad B, Zhu J
  Neurobiol Dis. 2004
  PubMed ID: 15262275
   
  
• Evolutionary genetics: Ambiguous role of CCR5 in Y. pestis infection.
  Elvin SJ, Williamson ED, Scott JC, Smith JN, Pérez De Lema G, Chilla S, Clapham P, Pfeffer K, Schlöndorff D, Luckow B
  Nature. 2004
  PubMed ID: 15272490
   
  
• CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and Gi proteins.
  Mueller A, Strange PG
  FEBS Lett. 2004
  PubMed ID: 15251452
   
  
• FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
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  J Immunol. 2004
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• Frequency of the CCR5-delta 32 chemokine receptor gene mutation in the Lebanese population.
  Karam W, Jurjus R, Khoury N, Khansa H, Assad C, Zalloua P, Jurjus A
  East Mediterr Health J. 2004
  PubMed ID: 16335661
   
  
• Rapid determination of the Delta32 deletion in the human CC-chemokine receptor 5 (CCR5) gene without DNA extraction by lightcycler real-time polymerase chain reaction.
  Nischalke HD, Nattermann J, Lichterfeld M, Woitas RP, Rockstroh JK, Sauerbruch T, Spengler U
  AIDS Res Hum Retroviruses. 2004
  PubMed ID: 15307921
   
  
• Is the CCR5-59029-G/G genotype a protective factor for cardiomyopathy in Chagas disease?
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  Hum Immunol. 2004
  PubMed ID: 15301862
   
  
• Association of highly active antiretroviral therapy failure with chemokine receptor 5 wild type.
  Bogner JR, Lutz B, Klein HG, Pollerer C, Troendle U, Goebel FD
  HIV Med. 2004
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• Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologies.
  Ruiz-Ferrer M, Barroso N, Antiñolo G, Aguilar-Reina J
  J Viral Hepat. 2004
  PubMed ID: 15230854
   
  
• CCR5 regulates high dose oral tolerance by modulating CC chemokine ligand 2 levels in the GALT.
  DePaolo RW, Lathan R, Karpus WJ
  J Immunol. 2004
  PubMed ID: 15210789
   
  
• pH-independent endocytic cycling of the chemokine receptor CCR5.
  Signoret N, Christophe T, Oppermann M, Marsh M
  Traffic. 2004
  PubMed ID: 15180829
   
  
• CCR5 promoter human haplogroups associated with HIV-1 disease progression in Thai injection drug users.
  Nguyen L, Li M, Chaowanachan T, Hu DJ, Vanichseni S, Mock PA, van Griensven F, Martin M, Sangkum U, Choopanya K, Tappero JW, Lal RB, Yang C
  AIDS. 2004
  PubMed ID: 15362666
   
  
• Increased adhesion molecule and chemokine receptor expression on CD8+ T cells trafficking to cerebrospinal fluid in HIV-1 infection.
  Shacklett BL, Cox CA, Wilkens DT, Karl Karlsson R, Nilsson A, Nixon DF, Price RW
  J Infect Dis. 2004
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• [Imbalanced T cell-specific transcription factors T-bet and GATA-3 contributes to type 2 T helper cell polarization in asthmatic patients].
  Liu CT, Wang G, Luo FM, Wang ZL, Liu R, Wang CL
  Zhonghua Jie He He Hu Xi Za Zhi. 2004
  PubMed ID: 15256090
   
  
• CCR5 receptor expression is down-regulated in HIV type 2 infection: implication for viral control and protection.
  Shea A, Sarr DA, Jones N, Penning L, Eisen G, Gueye-Ndiaye A, Mboup S, Kanki P, Cao H
  AIDS Res Hum Retroviruses. 2004
  PubMed ID: 15242539
   
  
• MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis.
  Peterson KE, Errett JS, Wei T, Dimcheff DE, Ransohoff R, Kuziel WA, Evans L, Chesebro B
  J Virol. 2004
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• Association of CCR5 delta32 deletion with early death in multiple sclerosis.
  Gade-Andavolu R, Comings DE, MacMurray J, Rostamkhani M, Cheng LS, Tourtellotte WW, Cone LA
  Genet Med. 2004
  PubMed ID: 15354329
   
  
• Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity.
  Reeves JD, Miamidian JL, Biscone MJ, Lee FH, Ahmad N, Pierson TC, Doms RW
  J Virol. 2004
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• Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients.
  Mascheretti S, Hinrichsen H, Ross S, Buggisch P, Hampe J, Foelsch UR, Schreiber S
  Clin Exp Immunol. 2004
  PubMed ID: 15086398
   
  
• Increase in CCR5 Delta32/Delta32 genotype in multiple sclerosis.
  Pulkkinen K, Luomala M, Kuusisto H, Lehtimäki T, Saarela M, Jalonen TO, Elovaara I
  Acta Neurol Scand. 2004
  PubMed ID: 15080861
   
  
• Role of CC chemokines in skeletal muscle functional restoration after injury.
  Warren GL, O'Farrell L, Summan M, Hulderman T, Mishra D, Luster MI, Kuziel WA, Simeonova PP
  Am J Physiol Cell Physiol. 2004
  PubMed ID: 15075201
   
  
• Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines.
  Ko J, Jang SW, Kim YS, Kim IS, Sung HJ, Kim HH, Park JY, Lee YH, Kim J, Na DS
  FASEB J. 2004
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• Influence of CCR5 delta32 polymorphism on multiple sclerosis susceptibility and disease course.
  Silversides JA, Heggarty SV, McDonnell GV, Hawkins SA, Graham CA
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• Lack of association of human chemokine receptor gene polymorphisms CCR2-64I and CCR5-Delta32 with autoimmune Addison's disease.
  Gambelunghe G, Ghaderi M, Gharizadeh B, Brozzetti A, Tortoioli C, Del Sindaco P, Sanjeevi CB, Hjelmström P, Sirsjö A, Nyren P, Santeusanio F, Falorni A
  Eur J Immunogenet. 2004
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• Differential sensitivities of pyrogenic chemokine fevers to CC chemokine receptor 5 antibodies.
  Tavares E, Miñano FJ
  Fundam Clin Pharmacol. 2004
  PubMed ID: 15066130
   
  
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
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  Nature. 2004
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• The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors.
  Billick E, Seibert C, Pugach P, Ketas T, Trkola A, Endres MJ, Murgolo NJ, Coates E, Reyes GR, Baroudy BM, Sakmar TP, Moore JP, Kuhmann SE
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• Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors.
  Pöhlmann S, Davis C, Meister S, Leslie GJ, Otto C, Reeves JD, Puffer BA, Papkalla A, Krumbiegel M, Marzi A, Lorenz S, Münch J, Doms RW, Kirchhoff F
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• Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection.
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  Blood. 2004
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• [VNTR-polymorphism of the PAH, e-NOS genes and deletion of the CCR5 gene in populations in the northern Caucasus]
  Korshunova TIu, Akhmetova VL, Kutuev IA, Khusainova RI, Guseĭnov GG, Khusnutdinova EK
  Genetika. 2004
  PubMed ID: 15125257
   
  
• Effects of human immunodeficiency virus type 1 infection on CCR5 and CXCR4 coreceptor expression on CD4 T lymphocyte subsets in infants and adolescents.
  Tuttle DL, Coberley CR, Xie X, Kou ZC, Sleasman JW, Goodenow MM
  AIDS Res Hum Retroviruses. 2004
  PubMed ID: 15117454
   
  
• Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States.
  Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
  J Acquir Immune Defic Syndr. 2004
  PubMed ID: 15076247
   
  
• Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis.
  Quinones MP, Ahuja SK, Jimenez F, Schaefer J, Garavito E, Rao A, Chenaux G, Reddick RL, Kuziel WA, Ahuja SS
  J Clin Invest. 2004
  PubMed ID: 15067318
   
  
• The amount of calcium-deficient hexagonal hydroxyapatite in aortic valves is influenced by gender and associated with genetic polymorphisms in patients with severe calcific aortic stenosis.
  Ortlepp JR, Schmitz F, Mevissen V, Weiss S, Huster J, Dronskowski R, Langebartels G, Autschbach R, Zerres K, Weber C, Hanrath P, Hoffmann R
  Eur Heart J. 2004
  PubMed ID: 15039132
   
  
• Blocking CC chemokine receptor (CCR) 1 and CCR5 during herpes simplex virus type 2 infection in vivo impairs host defence and perturbs the cytokine response.
  Sørensen LN, Paludan SR
  Scand J Immunol. 2004
  PubMed ID: 15030585
   
  
• CC chemokine receptor 5delta32 polymorphism-a risk factor for ischemic-type biliary lesions following orthotopic liver transplantation.
  Moench C, Uhrig A, Lohse AW, Otto G
  Liver Transpl. 2004
  PubMed ID: 15004773
   
  
• An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease.
  Welniak LA, Wang Z, Sun K, Kuziel W, Anver MR, Blazar BR, Murphy WJ
  Exp Hematol. 2004
  PubMed ID: 15003318
   
  
• Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals.
  Pollakis G, Abebe A, Kliphuis A, Chalaby MI, Bakker M, Mengistu Y, Brouwer M, Goudsmit J, Schuitemaker H, Paxton WA
  J Virol. 2004
  PubMed ID: 14990703
   
  
• Analysis of the involvement of CCR5-Delta32 and CCR2-V64I variants in the development of endometriosis.
  Antiñolo G, Fernández RM, Noval JA, Moliní JL, Borrego S
  Mol Hum Reprod. 2004
  PubMed ID: 14981141
   
  
• Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cells.
  Agrawal L, Lu X, Qingwen J, VanHorn-Ali Z, Nicolescu IV, McDermott DH, Murphy PM, Alkhatib G
  J Virol. 2004
  PubMed ID: 14963124
   
  
• Combined blockade of the chemokine receptors CCR1 and CCR5 attenuates chronic rejection.
  Yun JJ, Whiting D, Fischbein MP, Banerji A, Irie Y, Stein D, Fishbein MC, Proudfoot AE, Laks H, Berliner JA, Ardehali A
  Circulation. 2004
  PubMed ID: 14757698
   
  
• Specific inhibition of HIV-1 coreceptor activity by synthetic peptides corresponding to the predicted extracellular loops of CCR5.
  Agrawal L, VanHorn-Ali Z, Berger EA, Alkhatib G
  Blood. 2004
  PubMed ID: 14576050
   
  
• Evolutionary genetics: CCR5 mutation and plague protection.
  Mecsas J, Franklin G, Kuziel WA, Brubaker RR, Falkow S, Mosier DE
  Nature. 2004
  PubMed ID: 14961112
   
  
• Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice.
  Veillard NR, Kwak B, Pelli G, Mulhaupt F, James RW, Proudfoot AE, Mach F
  Circ Res. 2004
  PubMed ID: 14656931
   
  
• Analysis of the CC chemokine receptor 5 (CCR5) Delta32 polymorphism in Behçet's disease.
  Yang X, Ahmad T, Gogus F, Verity D, Wallace GR, Madanat W, Kanawati CA, Stanford MR, Fortune F, Jewell DP, Marshall SE
  Eur J Immunogenet. 2004
  PubMed ID: 15009175
   
  
• Chemokine receptor 5 is dispensable for innate and adaptive immune responses to Listeria monocytogenes infection.
  Zhong MX, Kuziel WA, Pamer EG, Serbina NV
  Infect Immun. 2004
  PubMed ID: 14742553
   
  
• Fraction of cases of acquired immunodeficiency syndrome prevented by the interactions of identified restriction gene variants.
  Silverberg MJ, Smith MW, Chmiel JS, Detels R, Margolick JB, Rinaldo CR, O'Brien SJ, Muñoz A
  Am J Epidemiol. 2004
  PubMed ID: 14742283
   
  
• Identification of amino acid residues crucial for chemokine receptor dimerization.
  Hernanz-Falcón P, Rodríguez-Frade JM, Serrano A, Juan D, del Sol A, Soriano SF, Roncal F, Gómez L, Valencia A, Martínez-A C, Mellado M
  Nat Immunol. 2004
  PubMed ID: 14716309
   
  
• Expression of chemokine receptors CXCR4, CCR2, CCR5 and CX3CR1 in neural progenitor cells isolated from the subventricular zone of the adult rat brain.
  Ji JF, He BP, Dheen ST, Tay SS
  Neurosci Lett. 2004
  PubMed ID: 14732474
   
  
• [Functional polymorphism of p53 and CCR5 genes in the long-lived of the Siberian region]
  Smetannikova MA, Beliavskaia VA, Smetannikova NA, Savkin IV, Denisova DV, Ustinov SN, Maksimov VN, Shabalin AV, Bolotnova TV, Voevoda MI
  Vestn Ross Akad Med Nauk. 2004
  PubMed ID: 15651660
   
  
• Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs.
  Seibert C, Sakmar TP
  Curr Pharm Des. 2004
  PubMed ID: 15279544
   
  
• CCR5 promoter polymorphism influences the interferon response of patients with chronic hepatitis C in Japan.
  Konishi I, Horiike N, Hiasa Y, Michitaka K, Onji M
  Intervirology. 2004
  PubMed ID: 15192276
   
  
• Stromal cell-derived factor (SDF) 1-3'A polymorphism may play a role in resistance to HIV-1 infection in seronegative high-risk Thais.
  Tiensiwakul P
  Intervirology. 2004
  PubMed ID: 15192272
   
  
• Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists.
  Princen K, Hatse S, Vermeire K, De Clercq E, Schols D
  Retrovirology. 2004
  PubMed ID: 15169555
   
  
• Prevalence of alleles associated with HIV resistance in Russia.
  Ryabov GS, Kazennova EV, Bobkova MR, Bobkov AF
  Genet Test. 2004
  PubMed ID: 15140377
   
  
• Chemokine receptor utilization and macrophage signaling by human immunodeficiency virus type 1 gp120: Implications for neuropathogenesis.
  Yi Y, Lee C, Liu QH, Freedman BD, Collman RG
  J Neurovirol. 2004
  PubMed ID: 14982745
   
  
• Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers.
  Shalekoff S, Gray GE, Tiemessen CT
  Clin Diagn Lab Immunol. 2004
  PubMed ID: 14715575
   
  
• Role of the ectodomain of the gp41 transmembrane envelope protein of human immunodeficiency virus type 1 in late steps of the membrane fusion process.
  Bär S, Alizon M
  J Virol. 2004
  PubMed ID: 14694113
   
  
• CC chemokine receptor 5 delta32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia.
  Wasmuth HE, Werth A, Mueller T, Berg T, Dietrich CG, Geier A, Schirin-Sokhan R, Gartung C, Lorenzen J, Matern S, Lammert F
  J Mol Med. 2004
  PubMed ID: 14673528
   
  
• Prevalence of the chemokine receptor CCR5-Delta32 gene mutation in periodontal disease.
  Folwaczny M, Glas J, Török HP, Fricke K, Folwaczny C
  Clin Immunol. 2003
  PubMed ID: 14697747
   
  
• Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis.
  Shahrara S, Amin MA, Woods JM, Haines GK, Koch AE
  Arthritis Rheum. 2003
  PubMed ID: 14674010
   
  
• Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection.
  Hellier S, Frodsham AJ, Hennig BJ, Klenerman P, Knapp S, Ramaley P, Satsangi J, Wright M, Zhang L, Thomas HC, Thursz M, Hill AV
  Hepatology. 2003
  PubMed ID: 14647058
   
  
• Chemokine-induced cell death in CCR5-expressing neuroblastoma cells.
  Cartier L, Dubois-Dauphin M, Hartley O, Irminger-Finger I, Krause KH
  J Neuroimmunol. 2003
  PubMed ID: 14644028
   
  
• Promoter polymorphism of IL-10 and severity of multiple sclerosis.
  Luomala M, Lehtimäki T, Huhtala H, Ukkonen M, Koivula T, Hurme M, Elovaara I
  Acta Neurol Scand. 2003
  PubMed ID: 14616291
   
  
• Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection.
  Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
  J Infect Dis. 2003
  PubMed ID: 14624371
   
  
• Cutting edge: IL-16/CD4 preferentially induces Th1 cell migration: requirement of CCR5.
  Lynch EA, Heijens CA, Horst NF, Center DM, Cruikshank WW
  J Immunol. 2003
  PubMed ID: 14607889
   
  
• CCR5 expression influences the progression of human breast cancer in a p53-dependent manner.
  Mañes S, Mira E, Colomer R, Montero S, Real LM, Gómez-Moutón C, Jiménez-Baranda S, Garzón A, Lacalle RA, Harshman K, Ruíz A, Martínez-A C
  J Exp Med. 2003
  PubMed ID: 14597737
   
  
• [Distribution of the HIV/AIDS associated CCR5Delta32,CCR2b-64I,SDF1-3'A allelesin Chinese Dai and Chingpaw populations from Dehong autonomous prefecture of Yunnan Province]
  Ye JJ, Wang FS, Peng L, Jin L, Ding M, Liu MX
  Yi Chuan. 2003
  PubMed ID: 15639953
   
  
• More about the Viking hypothesis of origin of the delta32 mutation in the CCR5 gene conferring resistance to HIV-1 infection.
  Lucotte G, Dieterlen F
  Infect Genet Evol. 2003
  PubMed ID: 14636691
   
  
• Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis.
  Field J, Marshall AC, J Hertzog P, Wells TN, Alderuccio F, Toh BH
  Clin Immunol. 2003
  PubMed ID: 14597223
   
  
• Structure and function of CC-chemokine receptor 5 homologues derived from representative primate species and subspecies of the taxonomic suborders Prosimii and Anthropoidea.
  Kunstman KJ, Puffer B, Korber BT, Kuiken C, Smith UR, Kunstman J, Stanton J, Agy M, Shibata R, Yoder AD, Pillai S, Doms RW, Marx P, Wolinsky SM
  J Virol. 2003
  PubMed ID: 14581567
   
  
• Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis.
  Zhao X, Gharizadeh B, Hjelmström P, Pirskanen R, Nyrén P, Lefvert AK, Ghaderi M
  Int J Mol Med. 2003
  PubMed ID: 14533004
   
  
• The relative activity of CXCR3 and CCR5 ligands in T lymphocyte migration: concordant and disparate activities in vitro and in vivo.
  Stanford MM, Issekutz TB
  J Leukoc Biol. 2003
  PubMed ID: 12960247
   
  
• Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.
  Lee C, Liu QH, Tomkowicz B, Yi Y, Freedman BD, Collman RG
  J Leukoc Biol. 2003
  PubMed ID: 12960231
   
  
• Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration.
  Schwabe RF, Bataller R, Brenner DA
  Am J Physiol Gastrointest Liver Physiol. 2003
  PubMed ID: 12829440
   
  
• Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages.
  Slimani H, Charnaux N, Mbemba E, Saffar L, Vassy R, Vita C, Gattegno L
  Biochim Biophys Acta. 2003
  PubMed ID: 14637022
   
  
• Predominant intracellular expression of CXCR4 and CCR5 in purified primary trophoblast cells from first trimester and term human placentae.
  Maldonado-Estrada J, Menu E, Roques P, Vaslin B, Dautry-Varsat A, Barré-Sinoussi F, Chaouat G
  Am J Reprod Immunol. 2003
  PubMed ID: 14672331
   
  
• Structural and functional characterization of the human CCR5 receptor in complex with HIV gp120 envelope glycoprotein and CD4 receptor by molecular modeling studies.
  Liu S, Fan S, Sun Z
  J Mol Model. 2003
  PubMed ID: 14517611
   
  
• Purified complexes of HIV-1 envelope glycoproteins with CD4 and CCR5(CXCR4): production, characterization and immunogenicity.
  Xiao X, Phogat S, Shu Y, Phogat A, Chow YH, Wei OL, Goldstein H, Broder CC, Dimitrov DS
  Vaccine. 2003
  PubMed ID: 14505910
   
  
• Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.
  Arias DA, Navenot JM, Zhang WB, Broach J, Peiper SC
  J Biol Chem. 2003
  PubMed ID: 12837756
   
  
• Blocking the docking of HIV-1.
  McKnight A, Weiss RA
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 12963807
   
  
• Variants of the chemokine receptor CCR5 are associated with severe bronchiolitis caused by respiratory syncytial virus.
  Hull J, Rowlands K, Lockhart E, Moore C, Sharland M, Kwiatkowski D
  J Infect Dis. 2003
  PubMed ID: 12964123
   
  
• CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells.
  Zhao X, Sato A, Dela Cruz CS, Linehan M, Luegering A, Kucharzik T, Shirakawa AK, Marquez G, Farber JM, Williams I, Iwasaki A
  J Immunol. 2003
  PubMed ID: 12960300
   
  
• Low CD4+ T-cell surface CCR5 density as a cause of resistance to in vivo HIV-1 infection.
  Reynes J, Baillat V, Portales P, Clot J, Corbeau P
  J Acquir Immune Defic Syndr. 2003
  PubMed ID: 14501804
   
  
• Early- and intermediate-stage variants of simian immunodeficiency virus replicate efficiently in cells lacking CCR5.
  Forte S, Harmon ME, Pineda MJ, Overbaugh J
  J Virol. 2003
  PubMed ID: 12915585
   
  
• Virus entry as a target for anti-HIV intervention.
  Esté JA
  Curr Med Chem. 2003
  PubMed ID: 12871111
   
  
• Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population.
  Munerato P, Azevedo ML, Sucupira MC, Pardini R, Pinto GH, Catroxo M, Souza IE, Diaz RS
  Braz J Infect Dis. 2003
  PubMed ID: 14533983
   
  
• Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4.
  Venkatesan S, Rose JJ, Lodge R, Murphy PM, Foley JF
  Mol Biol Cell. 2003
  PubMed ID: 12925765
   
  
• Functional analysis of the CC chemokine receptor 5 (CCR5) on virus-specific CD8+ T cells following coronavirus infection of the central nervous system.
  Glass WG, Lane TE
  Virology. 2003
  PubMed ID: 12919745
   
  
• Chemokine receptor CCR2/CCR5 polymorphism in Spanish patients with systemic lupus erythematosus.
  Aguilar F, Núñez-Roldán A, Torres B, Wichmann I, Sánchez-Román J, González-Escribano MF
  J Rheumatol. 2003
  PubMed ID: 12913933
   
  
• Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.
  Choe H, Li W, Wright PL, Vasilieva N, Venturi M, Huang CC, Grundner C, Dorfman T, Zwick MB, Wang L, Rosenberg ES, Kwong PD, Burton DR, Robinson JE, Sodroski JG, Farzan M
  Cell. 2003
  PubMed ID: 12887918
   
  
• CCR5 mimicry by sulfated human anti-HIV-1 antibodies.
  Lin G, Hoxie JA
  Cell. 2003
  PubMed ID: 12887913
   
  
• Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis.
  Ioannidis JP, Contopoulos-Ioannidis DG, Rosenberg PS, Goedert JJ, De Rossi A, Espanol T, Frenkel L, Mayaux MJ, Newell ML, Pahwa SG, Rousseau C, Scarlatti G, Sei S, Sen L, O'Brien TR, HIV Host Genetics International Meta-Analysis Group
  AIDS. 2003
  PubMed ID: 12853745
   
  
• A mutated CCR5 gene may have favorable prognostic implications in MS.
  Kantor R, Bakhanashvili M, Achiron A
  Neurology. 2003
  PubMed ID: 12874407
   
  
• HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors.
  Zaitseva M, Peden K, Golding H
  Biochim Biophys Acta. 2003
  PubMed ID: 12873765
   
  
• The HIV Env-mediated fusion reaction.
  Gallo SA, Finnegan CM, Viard M, Raviv Y, Dimitrov A, Rawat SS, Puri A, Durell S, Blumenthal R
  Biochim Biophys Acta. 2003
  PubMed ID: 12873764
   
  
• R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms.
  Kawamura T, Gulden FO, Sugaya M, McNamara DT, Borris DL, Lederman MM, Orenstein JM, Zimmerman PA, Blauvelt A
  Proc Natl Acad Sci U S A. 2003
  PubMed ID: 12815099
   
  
• The Delta 32 mutation of the chemokine-receptor 5 gene neither is correlated with chronic hepatitis C nor does it predict response to therapy with interferon-alpha and ribavirin.
  Glas J, Török HP, Simperl C, König A, Martin K, Schmidt F, Schaefer M, Schiemann U, Folwaczny C
  Clin Immunol. 2003
  PubMed ID: 12865070
   
  
• Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patients with Wegener's granulomatosis.
  Zhou Y, Huang D, Farver C, Hoffman GS
  J Rheumatol. 2003
  PubMed ID: 12858455
   
  
• Infiltrating CD8+ T cells in oral lichen planus predominantly express CCR5 and CXCR3 and carry respective chemokine ligands RANTES/CCL5 and IP-10/CXCL10 in their cytolytic granules: a potential self-recruiting mechanism.
  Iijima W, Ohtani H, Nakayama T, Sugawara Y, Sato E, Nagura H, Yoshie O, Sasano T
  Am J Pathol. 2003
  PubMed ID: 12819030
   
  
• The chemokine receptor CCR5 is not a necessary inflammatory mediator in kainic acid-induced hippocampal injury: evidence for a compensatory effect by increased CCR2 and CCR3.
  Chen Z, Yu S, Bakhiet M, Winblad B, Zhu J
  J Neurochem. 2003
  PubMed ID: 12807425
   
  
• Determination of the CCR2-64I/CCR5-59653T haplotype linkage disequilibrium in a sample of Polish population.
  Lewandowska M, Trzeciak WH, Jagodzinski PP
  Genetika. 2003
  PubMed ID: 12884524
   
  
• CCR5 delta32 heterozygosity is associated with an increase in CXCR4 cell surface expression.
  Shalekoff S, Tiemessen CT
  AIDS Res Hum Retroviruses. 2003
  PubMed ID: 12882661
   
  
• Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.
  TeKippe M, Harrison DE, Chen J
  Exp Hematol. 2003
  PubMed ID: 12829028
   
  
• Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression.
  LaBonte JA, Madani N, Sodroski J
  J Virol. 2003
  PubMed ID: 12767984
   
  
• Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2.
  Zaunders JJ, Moutouh-de Parseval L, Kitada S, Reed JC, Rought S, Genini D, Leoni L, Kelleher A, Cooper DA, Smith DE, Grey P, Estaquier J, Little S, Richman DD, Corbeil J
  J Infect Dis. 2003
  PubMed ID: 12751031
   
  
• CCR5 deficiency decreases susceptibility to experimental cerebral malaria.
  Belnoue E, Kayibanda M, Deschemin JC, Viguier M, Mack M, Kuziel WA, Rénia L
  Blood. 2003
  PubMed ID: 12560237
   
  
• Biological relevance of the polymorphism in the CCR5 gene in refractory and non-refractory rheumatoid arthritis in Mexicans.
  Zúñiga JA, Villarreal-Garza C, Flores E, Barquera R, Pérez-Hernández N, Montes de Oca JV, Cardiel MH, Vargas-Alarcón G, Granados J
  Clin Exp Rheumatol. 2003
  PubMed ID: 12846056
   
  
• Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry.
  Tsamis F, Gavrilov S, Kajumo F, Seibert C, Kuhmann S, Ketas T, Trkola A, Palani A, Clader JW, Tagat JR, McCombie S, Baroudy B, Moore JP, Sakmar TP, Dragic T
  J Virol. 2003
  PubMed ID: 12692222
   
  
• Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells.
  Aliberti J, Valenzuela JG, Carruthers VB, Hieny S, Andersen J, Charest H, Reis e Sousa C, Fairlamb A, Ribeiro JM, Sher A
  Nat Immunol. 2003
  PubMed ID: 12665855
   
  
• Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication.
  Steele AD, Henderson EE, Rogers TJ
  Virology. 2003
  PubMed ID: 12726730
   
  
• Host absence of CCR5 potentiates dendritic cell vaccination.
  Ng-Cashin J, Kuhns JJ, Burkett SE, Powderly JD, Craven RR, van Deventer HW, Kirby SL, Serody JS
  J Immunol. 2003
  PubMed ID: 12682253
   
  
• YY1 transcription factor down-regulates expression of CCR5, a major coreceptor for HIV-1.
  Moriuchi M, Moriuchi H
  J Biol Chem. 2003
  PubMed ID: 12571248
   
  
• Hormonal and embryonic regulation of chemokine receptors CXCR1, CXCR4, CCR5 and CCR2B in the human endometrium and the human blastocyst.
  Dominguez F, Galan A, Martin JJ, Remohi J, Pellicer A, Simón C
  Mol Hum Reprod. 2003
  PubMed ID: 12651900
   
  
• The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C.
  Cilliers T, Nhlapo J, Coetzer M, Orlovic D, Ketas T, Olson WC, Moore JP, Trkola A, Morris L
  J Virol. 2003
  PubMed ID: 12634405
   
  
• Evidence for CD4-enchanced signaling through the chemokine receptor CCR5.
  Staudinger R, Phogat SK, Xiao X, Wang X, Dimitrov DS, Zolla-Pazner S
  J Biol Chem. 2003
  PubMed ID: 12531905
   
  
• Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types.
  Ketas TJ, Klasse PJ, Spenlehauer C, Nesin M, Frank I, Pope M, Strizki JM, Reyes GR, Baroudy BM, Moore JP
  AIDS Res Hum Retroviruses. 2003
  PubMed ID: 12689409
   
  
• Genetic footprinting of the HIV co-receptor CCR5: delineation of surface expression and viral entry determinants.
  Quinonez R, Sinha I, Singh IR, Sutton RE
  Virology. 2003
  PubMed ID: 12667818
   
  
• CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice.
  Kuziel WA, Dawson TC, Quinones M, Garavito E, Chenaux G, Ahuja SS, Reddick RL, Maeda N
  Atherosclerosis. 2003
  PubMed ID: 12618265
   
  
• High frequency of CCR5-delta32 homozygosity in HCV-infected, HIV-1-uninfected hemophiliacs results from resistance to HIV-1.
  Zhang M, Goedert JJ, O'Brien TR
  Gastroenterology. 2003
  PubMed ID: 12612937
   
  
• Association of CCR5Delta32 with reduced risk of childhood but not adult asthma.
  Srivastava P, Helms PJ, Stewart D, Main M, Russell G
  Thorax. 2003
  PubMed ID: 12612298
   
  
• Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization.
  Suphaphiphat P, Thitithanyanont A, Paca-Uccaralertkun S, Essex M, Lee TH
  J Virol. 2003
  PubMed ID: 12610158
   
  
• RANTES promoter genotype is associated with diabetic nephropathy in type 2 diabetic subjects.
  Nakajima K, Tanaka Y, Nomiyama T, Ogihara T, Ikeda F, Kanno R, Iwashita N, Sakai K, Watada H, Onuma T, Kawamori R
  Diabetes Care. 2003
  PubMed ID: 12610055
   
  
• Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation.
  Croitoru-Lamoury J, Guillemin GJ, Boussin FD, Mognetti B, Gigout LI, Chéret A, Vaslin B, Le Grand R, Brew BJ, Dormont D
  Glia. 2003
  PubMed ID: 12555203
   
  
• Cytokine response to endotoxin in individuals heterozygous for the Delta32 mutation of chemokine receptor CCR5.
  Heesen M, Schippers EF, Bloemeke B, Kunz D, van Dissel JT
  Cytokine. 2003
  PubMed ID: 12788308
   
  
• CC chemokine receptor 5 genotype and susceptibility to transmission of human immunodeficiency virus type 1 in women.
  Philpott S, Weiser B, Tarwater P, Vermund SH, Kleeberger CA, Gange SJ, Anastos K, Cohen M, Greenblatt RM, Kovacs A, Minkoff H, Young MA, Miotti P, Dupuis M, Chen CH, Burger H
  J Infect Dis. 2003
  PubMed ID: 12599073
   
  
• Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection.
  Mulherin SA, O'Brien TR, Ioannidis JP, Goedert JJ, Buchbinder SP, Coutinho RA, Jamieson BD, Meyer L, Michael NL, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Theodorou ID, Vlahov D, Rosenberg PS, International Meta-Analysis of HIV Host Genetics
  AIDS. 2003
  PubMed ID: 12556692
   
  
• Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes.
  Lehoux G, Le Gouill C, Stankova J, Rola-Pleszczynski M
  Mediators Inflamm. 2003
  PubMed ID: 12745546
   
  
• [Single nucleotide polymorphism loci of HIV-1 coreceptor CCR5 gene in Chinese Han people]
  Liu MX, Wang FS, Hong WG, Wang B, Jin L, Lei ZY, Hou J
  Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003
  PubMed ID: 12579509
   
  
• Population survey of CCR5 delta32, CCR5 m303, CCR2b 64I, and SDF1 3'A allele frequencies in indigenous Chinese healthy individuals, and in HIV-1-infected and HIV-1-uninfected individuals in HIV-1 risk groups.
  Wang FS, Hong WG, Cao Y, Liu MX, Jin L, Hu LP, Wang Z, Feng TJ, Hou J, Zhang B, Shi M, Xu DP, Lei ZY, Wang B, Liu ZD, Ye JJ, Peng L, Qiu Y, Winkler C
  J Acquir Immune Defic Syndr. 2003
  PubMed ID: 12571520
   
  
• Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C.
  Promrat K, McDermott DH, Gonzalez CM, Kleiner DE, Koziol DE, Lessie M, Merrell M, Soza A, Heller T, Ghany M, Park Y, Alter HJ, Hoofnagle JH, Murphy PM, Liang TJ
  Gastroenterology. 2003
  PubMed ID: 12557141
   
  
• Sustained inhibition of corneal neovascularization by genetic ablation of CCR5.
  Ambati BK, Anand A, Joussen AM, Kuziel WA, Adamis AP, Ambati J
  Invest Ophthalmol Vis Sci. 2003
  PubMed ID: 12556387
   
  
• Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.
  François F, Klotman ME
  J Virol. 2003
  PubMed ID: 12551992
   
  
• Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction.
  Murai M, Yoneyama H, Ezaki T, Suematsu M, Terashima Y, Harada A, Hamada H, Asakura H, Ishikawa H, Matsushima K
  Nat Immunol. 2003
  PubMed ID: 12524535
   
  
• Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies.
  Pollok-Kopp B, Schwarze K, Baradari VK, Oppermann M
  J Biol Chem. 2003
  PubMed ID: 12403770
   
  
• Limited protective effect of the CCR5Delta32/CCR5Delta32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus.
  Iversen AK, Christiansen CB, Attermann J, Eugen-Olsen J, Schulman S, Berntorp E, Ingerslev J, Fugger L, Scheibel E, Tengborn L, Gerstoft J, Dickmeiss E, Svejgaard A, Skinhøj P
  J Infect Dis. 2003
  PubMed ID: 12552446
   
  
• Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking.
  Lipp M, Müller G
  Verh Dtsch Ges Pathol. 2003
  PubMed ID: 16888899
   
  
• CCR5-Delta32 allele frequencies in Ashkenazi Jews.
  Lucotte G, Smets P
  Genet Test. 2003
  PubMed ID: 15000812
   
  
• HIV-1 gp120 chemokine receptor-mediated signaling in human macrophages.
  Freedman BD, Liu QH, Del Corno M, Collman RG
  Immunol Res. 2003
  PubMed ID: 12857973
   
  
• CCR5 and CCR2 gene polymorphisms in hypertensive patients.
  Mettimano M, Specchia ML, Ianni A, Arzani D, Ricciardi G, Savi L, Romano-Spica V
  Br J Biomed Sci. 2003
  PubMed ID: 12680626
   
  
• Chemokine receptor genotype and response to interleukin-2 therapy in HIV-1-infected individuals.
  Clegg A, Williamson P, Biti R, Cooper D, Emery S, Carr A, Stewart G
  Clin Immunol. 2003
  PubMed ID: 12584049
   
  
• High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia.
  Chies JA, Hutz MH
  Braz J Med Biol Res. 2003
  PubMed ID: 12532229
   
  
• Chemokine receptor 5 expression in gastric mucosa of Helicobacter pylori-infected and noninfected children.
  Krauss-Etschmann S, Sammler E, Koletzko S, Konstantopoulos N, Aust D, Gebert B, Luckow B, Reinhardt D, Schendel DJ
  Clin Diagn Lab Immunol. 2003
  PubMed ID: 12522035
   
  
• Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: a meta-analysis.
  Contopoulos-Ioannidis DG, O'Brien TR, Goedert JJ, Rosenberg PS, Ioannidis JP
  J Acquir Immune Defic Syndr. 2003
  PubMed ID: 12514416
   
  
• CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5.
  Raja A, Venturi M, Kwong P, Sodroski J
  J Virol. 2003
  PubMed ID: 12477875
   
  
• Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
  Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12477932
   
  
• CC chemokine receptor 5 delta32 and CC chemokine receptor 2 64I polymorphisms do not influence the virologic and immunologic response to antiretroviral combination therapy in human immunodeficiency virus type 1-infected patients.
  Wit FW, van Rij RP, Weverling GJ, Lange JM, Schuitemaker H
  J Infect Dis. 2002
  PubMed ID: 12447757
   
  
• Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections.
  Zheng BJ, Zhao XY, Zhu NS, Chan CP, Wong KH, Chan KC, Yam WC, Yuen KY, Lee SS
  AIDS. 2002
  PubMed ID: 12461425
   
  
• The N-linked glycan g15 within the V3 loop of the HIV-1 external glycoprotein gp120 affects coreceptor usage, cellular tropism, and neutralization.
  Polzer S, Dittmar MT, Schmitz H, Schreiber M
  Virology. 2002
  PubMed ID: 12490404
   
  
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
  Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
  Nature. 2002
  PubMed ID: 12466851
   
  
• A new possible mechanism of human immunodeficiency virus type 1 infection of neural cells.
  Alvarez Losada S, Cantó-Nogués C, Muñoz-Fernández MA
  Neurobiol Dis. 2002
  PubMed ID: 12586555
   
  
• Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity.
  Paterlini MG
  Biophys J. 2002
  PubMed ID: 12496074
   
  
• Further support for the association of CCR5 allelic variants with asthma susceptibility.
  McGinnis R, Child F, Clayton S, Davies S, Lenney W, Illig T, Wjst M, Spurr N, Debouck C, Hajeer AH, Ollier WE, Strange R, Fryer AA
  Eur J Immunogenet. 2002
  PubMed ID: 12437612
   
  
• The chemokine receptor CCR5 deletion mutation is associated with MS in HLA-DR4-positive Russians.
  Favorova OO, Andreewski TV, Boiko AN, Sudomoina MA, Alekseenkov AD, Kulakova OG, Slanova AV, Gusev EI
  Neurology. 2002
  PubMed ID: 12451219
   
  
• Characterization of the role of the N-loop of MIP-1 beta in CCR5 binding.
  Bondue A, Jao SC, Blanpain C, Parmentier M, LiWang PJ
  Biochemistry. 2002
  PubMed ID: 12427015
   
  
• Exportin-5-mediated nuclear export of eukaryotic elongation factor 1A and tRNA.
  Calado A, Treichel N, Müller EC, Otto A, Kutay U
  EMBO J. 2002
  PubMed ID: 12426393
   
  
• Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.
  Bohnsack MT, Regener K, Schwappach B, Saffrich R, Paraskeva E, Hartmann E, Görlich D
  EMBO J. 2002
  PubMed ID: 12426392
   
  
• Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes.
  Rey M, Vicente-Manzanares M, Viedma F, Yáñez-Mó M, Urzainqui A, Barreiro O, Vázquez J, Sánchez-Madrid F
  J Immunol. 2002
  PubMed ID: 12421915
   
  
• [Identification of new mutant sites and 894C deletion variant genotyping of HIV-1 coreceptor CCR5 in indigenous Chinese populations]
  Liu M, Wang F, Hong W, Wang B, Jin L, Lei Z, Hou J
  Zhonghua Yi Xue Za Zhi. 2002
  PubMed ID: 12509908
   
  
• Ionic interaction of the HIV-1 V3 domain with CCR5 and deregulation of T lymphocyte function.
  Baritaki S, Zafiropoulos A, Sioumpara M, Politis M, Spandidos DA, Krambovitis E
  Biochem Biophys Res Commun. 2002
  PubMed ID: 12408990
   
  
• Analysis of gene polymorphisms in the regulatory region of MCP-1, RANTES, and CCR5 in liver transplant recipients.
  Schröppel B, Fischereder M, Lin M, Marder B, Schiano T, Krämer BK, Murphy B
  J Clin Immunol. 2002
  PubMed ID: 12462338
   
  
• Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.
  Kiss H, Darai E, Kiss C, Kost-Alimova M, Klein G, Dumanski JP, Imreh S
  Mamm Genome. 2002
  PubMed ID: 12461651
   
  
• Multiple determinants are involved in HIV coreceptor use as demonstrated by CCR4/CCL22 interaction in peripheral blood mononuclear cells (PBMCs).
  Agrawal L, Vanhorn-Ali Z, Alkhatib G
  J Leukoc Biol. 2002
  PubMed ID: 12429730
   
  
• CCR5 genotype and plasma beta-chemokine concentration of Brazilian HIV-infected individuals.
  Mikawa AY, Tagliavini SA, Costa PI
  Braz J Med Biol Res. 2002
  PubMed ID: 12426633
   
  
• Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells.
  Suzuki S, Chuang LF, Yau P, Doi RH, Chuang RY
  Exp Cell Res. 2002
  PubMed ID: 12413885
   
  
• Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding.
  Basmaciogullari S, Babcock GJ, Van Ryk D, Wojtowicz W, Sodroski J
  J Virol. 2002
  PubMed ID: 12368322
   
  
• Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region.
  Farzan M, Chung S, Li W, Vasilieva N, Wright PL, Schnitzler CE, Marchione RJ, Gerard C, Gerard NP, Sodroski J, Choe H
  J Biol Chem. 2002
  PubMed ID: 12183462
   
  
• The presence of chemokine (MCP-1, MIP-1alpha, MIP-1beta, IP-10, RANTES)-positive cells and chemokine receptor (CCR5, CXCR3)-positive cells in inflamed human gingival tissues.
  Kabashima H, Yoneda M, Nagata K, Hirofuji T, Maeda K
  Cytokine. 2002
  PubMed ID: 12445801
   
  
• Rescue of HIV-1 receptor function through cooperation between different forms of the CCR5 chemokine receptor.
  Chelli M, Alizon M
  J Biol Chem. 2002
  PubMed ID: 12154092
   
  
• Dichotomous effects of Plasmodium falciparum antigens on expression of human immunodeficiency virus (HIV) coreceptors and on infectability of CD4 cells by HIV.
  Moriuchi M, Moriuchi H, Mon HM, Kanbara H
  J Infect Dis. 2002
  PubMed ID: 12355376
   
  
• IFN-gamma and IL-12 differentially regulate CC-chemokine secretion and CCR5 expression in human T lymphocytes.
  Losana G, Bovolenta C, Rigamonti L, Borghi I, Altare F, Jouanguy E, Forni G, Casanova JL, Sherry B, Mengozzi M, Trinchieri G, Poli G, Gerosa F, Novelli F
  J Leukoc Biol. 2002
  PubMed ID: 12377943
   
  
• Expression of chemokine receptors in the different clinical forms of multiple sclerosis.
  Martínez-Cáceres EM, Espejo C, Brieva L, Pericot I, Tintoré M, Sáez-Torres I, Montalban X
  Mult Scler. 2002
  PubMed ID: 12356205
   
  
• CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor.
  Honczarenko M, Le Y, Glodek AM, Majka M, Campbell JJ, Ratajczak MZ, Silberstein LE
  Blood. 2002
  PubMed ID: 12239139
   
  
• Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma.
  Abe M, Hiura K, Wilde J, Moriyama K, Hashimoto T, Ozaki S, Wakatsuki S, Kosaka M, Kido S, Inoue D, Matsumoto T
  Blood. 2002
  PubMed ID: 12200385
   
  
• Increased number of CCR5+ CD4 T cells among south Indian adults probably associated with the low frequency of X4 phenotype of HIV-1 in India.
  Ramalingam S, Kannangai R, Vijayakumar TS, Subramanian S, Abraham OC, Rupali P, Jesudason MV, Sridharan G
  Indian J Med Res. 2002
  PubMed ID: 12619446
   
  
• CC chemokine receptor 5 and interleukin-1 receptor antagonist gene polymorphisms in patients with primary Sjögren's syndrome.
  Petrek M, Cermáková Z, Hutyrová B, Miceková D, Drábek J, Rovensky J, Bosák V
  Clin Exp Rheumatol. 2002
  PubMed ID: 12412204
   
  
• Distribution of the CCR5 gene 32-basepair deletion in 11 Chinese populations.
  Zhang C, Fu S, Xue Y, Wang Q, Huang X, Wang B, Liu A, Ma L, Yu Y, Shi R, Lv F, Shi Z, Zhang Y, Cheng W, Ai Q, Xu F, Huang C, Chen B, Kang X, Sun Y, Zhang G, Li P
  Anthropol Anz. 2002
  PubMed ID: 12378793
   
  
• The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor.
  Cormier EG, Dragic T
  J Virol. 2002
  PubMed ID: 12163614
   
  
• Human alpha-fetoprotein binds to primary macrophages.
  Atemezem A, Mbemba E, Marfaing R, Vaysse J, Pontet M, Saffar L, Charnaux N, Gattegno L
  Biochem Biophys Res Commun. 2002
  PubMed ID: 12176010
   
  
• Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif.
  Huttenrauch F, Nitzki A, Lin FT, Höning S, Oppermann M
  J Biol Chem. 2002
  PubMed ID: 12065593
   
  
• Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence.
  Seibert C, Cadene M, Sanfiz A, Chait BT, Sakmar TP
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12169668
   
  
• Chemokine receptor CCR5: polymorphism at protein level.
  Suzuki S, Miyagi T, Chuang LF, Yau PM, Doi RH, Chuang RY
  Biochem Biophys Res Commun. 2002
  PubMed ID: 12163044
   
  
• Role of nucleotide sequences in the V3 region in efficient replication of CCR5-utilizing human immunodeficiency virus type 1 in macrophages.
  Harada T, Tsunetsugu-Yokota Y, Koyanagi Y, Sata T, Kurata T, Kojima A
  Virology. 2002
  PubMed ID: 12202222
   
  
• The impact of polymorphisms in chemokine and chemokine receptors on outcomes in liver transplantation.
  Schröppel B, Fischereder M, Ashkar R, Lin M, Krämer BK, Mardera B, Schiano T, Murphy B
  Am J Transplant. 2002
  PubMed ID: 12201365
   
  
• Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRB1*1501, CCR5 deletion mutation, apolipoprotein E).
  Schreiber K, Otura AB, Ryder LP, Madsen HO, Jørgensen OS, Svejgaard A, Sorensen PS
  Mult Scler. 2002
  PubMed ID: 12166499
   
  
• Regional variation in CCR5-Delta32 gene distribution among women from the US HIV Epidemiology Research Study (HERS).
  Downer MV, Hodge T, Smith DK, Qari SH, Schuman P, Mayer KH, Klein RS, Vlahov D, Gardner LI, McNicholl JM
  Genes Immun. 2002
  PubMed ID: 12140749
   
  
• CCR5 mediates Fas- and caspase-8 dependent apoptosis of both uninfected and HIV infected primary human CD4 T cells.
  Algeciras-Schimnich A, Vlahakis SR, Villasis-Keever A, Gomez T, Heppelmann CJ, Bou G, Paya CV
  AIDS. 2002
  PubMed ID: 12131184
   
  
• Transepithelial transport of HIV-1 by M cells is receptor-mediated.
  Fotopoulos G, Harari A, Michetti P, Trono D, Pantaleo G, Kraehenbuhl JP
  Proc Natl Acad Sci U S A. 2002
  PubMed ID: 12093918
   
  
• [The HIV-infection outbreak in the town Lys'va (Perm region): homozygote genotype CCR5 delta32/CCR5 delta32 provides the high level of the persistence in the parenteral transmission of the virus]
  Riabov GS, Kazennova EV, Korepanova LB, Mal'tseva EA, Zhalnin VV, Krasnikova LA, Zverev SIa, Pokrovskiĭ VV, Bobkov AF, Weber JN
  Vopr Virusol. 2002
  PubMed ID: 12271718
   
  
• Prevalence of the CCR5Delta32 mutation in Brazilian populations and cell susceptibility to HIV-1 infection.
  Grimaldi R, Shindo N, Acosta AX, Dourado I, Brites C, de Melo Carvalho O, Brito I, Bou-Habib DC, Galvão-Castro B
  Hum Genet. 2002
  PubMed ID: 12136242
   
  
• Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.
  Greene WC, Peterlin BM
  Nat Med. 2002
  PubMed ID: 12091904
   
  
• Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity.
  Kim CH, Johnston B, Butcher EC
  Blood. 2002
  PubMed ID: 12070001
   
  
• Reduced CC chemokine receptor (CCR) 1 and CCR5 surface expression on peripheral blood T lymphocytes from patients with chronic hepatitis C infection.
  Lichterfeld M, Leifeld L, Nischalke HD, Rockstroh JK, Hess L, Sauerbruch T, Spengler U
  J Infect Dis. 2002
  PubMed ID: 12085329
   
  
• Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.
  Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A
  J Immunol. 2002
  PubMed ID: 12055206
   
  
• Cholesterol is essential for macrophage inflammatory protein 1 beta binding and conformational integrity of CC chemokine receptor 5.
  Nguyen DH, Taub D
  Blood. 2002
  PubMed ID: 12036855
   
  
• Crucial role of CCL3/MIP-1alpha in the recurrence of autoimmune anterior uveitis induced with myelin basic protein in Lewis rats.
  Manczak M, Jiang S, Orzechowska B, Adamus G
  J Autoimmun. 2002
  PubMed ID: 12144807
   
  
• Frequency of the HIV-protective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C.
  Woitas RP, Ahlenstiel G, Iwan A, Rockstroh JK, Brackmann HH, Kupfer B, Matz B, Offergeld R, Sauerbruch T, Spengler U
  Gastroenterology. 2002
  PubMed ID: 12055576
   
  
• Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8.
  Oliveira SH, Lira S, Martinez-A C, Wiekowski M, Sullivan L, Lukacs NW
  J Leukoc Biol. 2002
  PubMed ID: 12050188
   
  
• No association between asthma or allergy and the CCR5Delta 32 mutation.
  Nagy A, Kozma GT, Bojszkó A, Krikovszky D, Falus A, Szalai C
  Arch Dis Child. 2002
  PubMed ID: 12023175
   
  
• CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway.
  Fernandis AZ, Cherla RP, Chernock RD, Ganju RK
  J Biol Chem. 2002
  PubMed ID: 11877445
   
  
• Patterns of chemokine receptor expression on peripheral blood gamma delta T lymphocytes: strong expression of CCR5 is a selective feature of V delta 2/V gamma 9 gamma delta T cells.
  Glatzel A, Wesch D, Schiemann F, Brandt E, Janssen O, Kabelitz D
  J Immunol. 2002
  PubMed ID: 11994442
   
  
• Frequencies of 32 base pair deletion of the (Delta 32) allele of the CCR5 HIV-1 co-receptor gene in Caucasians: a comparative analysis.
  Lucotte G
  Infect Genet Evol. 2002
  PubMed ID: 12798016
   
  
• Prevalence of HIV co-receptor polymorphisms in HIV-infected patients and uninfected volunteers in Luxembourg.
  Roman F, Franck N, Burgy C, Servais J, Zimmer JM, Mossong J, Goubau P, Schneider F, Hemmer R, Schmit JC
  HIV Clin Trials. 2002
  PubMed ID: 12032878
   
  
• Localization and expression of CCR3 and CCR5 by interleukin-1 beta in the RIN-5AH insulin-producing model system: a protective mechanism involving down-regulation of chemokine receptors.
  Vassiliadis S, Balabanidou V, Papadopoulos GK, Athanassakis I
  JOP. 2002
  PubMed ID: 12004163
   
  
• Chemokine receptor gene polymorphisms and risk of human T lymphotropic virus type I infection in Jamaica.
  Hisada M, Lal RB, Masciotra S, Rudolph DL, Martin MP, Carrington M, Wilks RJ, Manns A
  J Infect Dis. 2002
  PubMed ID: 12001056
   
  
• Study of the HIV-1 receptors CD4, CXCR4, CCR5 and CCR3 in the human and rat testis.
  Habasque C, Aubry F, Jégou B, Samson M
  Mol Hum Reprod. 2002
  PubMed ID: 11994538
   
  
• CCR2 and CCR5 genotypes in HIV type 1-infected adolescents: limited contributions to variability in plasma HIV type 1 RNA concentration in the absence of antiretroviral therapy.
  Tang J, Wilson CM, Schaen M, Myracle A, Douglas SD, Kaslow RA, REACH Study Group
  AIDS Res Hum Retroviruses. 2002
  PubMed ID: 11958683
   
  
• Heterozygosity for CCR5-Delta32 but not CCR2b-64I protects against certain intracellular pathogens.
  Ashton LJ, Stewart GJ, Biti R, Law M, Cooper DA, Kaldor JM
  HIV Med. 2002
  PubMed ID: 12010355
   
  
• Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites.
  Milliken D, Scotton C, Raju S, Balkwill F, Wilson J
  Clin Cancer Res. 2002
  PubMed ID: 11948121
   
  
• Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity.
  Abdulaev NG, Strassmaier TT, Ngo T, Chen R, Luecke H, Oprian DD, Ridge KD
  Structure. 2002
  PubMed ID: 11937056
   
  
• Expression of human immunodeficiency virus coreceptors CXC chemokine receptor 4 and CC chemokine receptor 5 on monocytes is down-regulated during human endotoxemia.
  Juffermans NP, Weijer S, Verbon A, Speelman P, van der Poll T
  J Infect Dis. 2002
  PubMed ID: 11920324
   
  
• Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines.
  Wang J, Crawford K, Yuan M, Wang H, Gorry PR, Gabuzda D
  J Infect Dis. 2002
  PubMed ID: 11920312
   
  
• Chemokine receptor polymorphisms and GB virus C status in HIV-positive patients.
  Tillmann HL, Stoll M, Manns MP, Schmidt RE, Heiken H
  AIDS. 2002
  PubMed ID: 11964548
   
  
• Elevated expression of CCR5 by myeloid (CD11c+) blood dendritic cells in multiple sclerosis and acute optic neuritis.
  Pashenkov M, Teleshova N, Kouwenhoven M, Kostulas V, Huang YM, Soderstrom M, Link H
  Clin Exp Immunol. 2002
  PubMed ID: 11966770
   
  
• Graves' disease is associated with an altered CXCR3 and CCR5 expression in thyroid-derived compared to peripheral blood lymphocytes.
  Aust G, Sittig D, Steinert M, Lamesch P, Lohmann T
  Clin Exp Immunol. 2002
  PubMed ID: 11966764
   
  
• HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion.
  Sheppard HW, Celum C, Michael NL, O'Brien S, Dean M, Carrington M, Dondero D, Buchbinder SP
  J Acquir Immune Defic Syndr. 2002
  PubMed ID: 11873082
   
  
• CCR5 and CXCR4 usage by non-clade B human immunodeficiency virus type 1 primary isolates.
  Thompson DA, Cormier EG, Dragic T
  J Virol. 2002
  PubMed ID: 11861874
   
  
• Antibody-mediated enhancement of human immunodeficiency virus type 1 infectivity is determined by the structure of gp120 and depends on modulation of the gp120-CCR5 interaction.
  Guillon C, Schutten M, Boers PH, Gruters RA, Osterhaus AD
  J Virol. 2002
  PubMed ID: 11861850
   
  
• Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription.
  Takeba Y, Nagafuchi H, Takeno M, Kashiwakura J, Suzuki N
  J Immunol. 2002
  PubMed ID: 11859127
   
  
• Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation.
  Abdi R, Tran TB, Sahagun-Ruiz A, Murphy PM, Brenner BM, Milford EL, McDermott DH
  J Am Soc Nephrol. 2002
  PubMed ID: 11856781
   
  
• CC chemokine receptor 5 (CCR5) mRNA expression in pulmonary sarcoidosis.
  Petrek M, Gibejova A, Drabek J, Mrazek F, Kolek V, Weigl E, du Bois RM
  Immunol Lett. 2002
  PubMed ID: 11803051
   
  
• The role of CC chemokine receptor 5 in antiviral immunity.
  Nansen A, Christensen JP, Andreasen SØ, Bartholdy C, Christensen JE, Thomsen AR
  Blood. 2002
  PubMed ID: 11830471
   
  
• Identification of amino acid residues critical for LD78beta, a variant of human macrophage inflammatory protein-1alpha, binding to CCR5 and inhibition of R5 human immunodeficiency virus type 1 replication.
  Miyakawa T, Obaru K, Maeda K, Harada S, Mitsuya H
  J Biol Chem. 2002
  PubMed ID: 11734558
   
  
• Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
  Zamarchi R, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A
  Clin Exp Immunol. 2002
  PubMed ID: 11876757
   
  
• The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice.
  Schuh JM, Blease K, Hogaboam CM
  FASEB J. 2002
  PubMed ID: 11744622
   
  
• Increased macrophage inflammatory protein-1alpha and macrophage inflammatory protein-1beta levels in bronchoalveolar lavage fluid of patients affected by different stages of pulmonary sarcoidosis.
  Capelli A, Di Stefano A, Lusuardi M, Gnemmi I, Donner CF
  Am J Respir Crit Care Med. 2002
  PubMed ID: 11790661
   
  
• The role of the CD4 receptor versus HIV coreceptors in envelope-mediated apoptosis in peripheral blood mononuclear cells.
  Arthos J, Cicala C, Selig SM, White AA, Ravindranath HM, Van Ryk D, Steenbeke TD, Machado E, Khazanie P, Hanback MS, Hanback DB, Rabin RL, Fauci AS
  Virology. 2002
  PubMed ID: 11878912
   
  
• Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study.
  Fellay J, Marzolini C, Meaden ER, Back DJ, Buclin T, Chave JP, Decosterd LA, Furrer H, Opravil M, Pantaleo G, Retelska D, Ruiz L, Schinkel AH, Vernazza P, Eap CB, Telenti A, Swiss HIV Cohort Study
  Lancet. 2002
  PubMed ID: 11809184
   
  
• Frequency analysis of the CCR5delta32 mutation in patients with brucellosis.
  Skendros P, Boura P, Tsantas N, Debre P, Theodorou I
  Scand J Infect Dis. 2002
  PubMed ID: 12587636
   
  
• C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection.
  Dorak MT, Folayan GO, Niwas S, van Leeuwen DJ, Yee LJ, Tang J, Kaslow RA
  Immunol Res. 2002
  PubMed ID: 12403355
   
  
• Frequency of CCR5 Gene 32-bp deletion in Pakistani ethnic groups.
  Khaliq S, Hameed A, Ayub Q, Mazhar K, Mohyuddin A, Mansoor A, Mehdi SQ
  Genet Test. 2002
  PubMed ID: 12215252
   
  
• Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.
  Zee RY, Hoh J, Cheng S, Reynolds R, Grow MA, Silbergleit A, Walker K, Steiner L, Zangenberg G, Fernandez-Ortiz A, Macaya C, Pintor E, Fernandez-Cruz A, Ott J, Lindpainter K
  Pharmacogenomics J. 2002
  PubMed ID: 12082592
   
  
• Decreased density of the CCR5 receptor on the surface of CD4+ lymphocytes and monocytes/macrophages is associated with the CCR5-59653T transition in the promoter region.
  Lewandowska M, Jagodzinski PP, Trzeciak WH
  Folia Histochem Cytobiol. 2002
  PubMed ID: 12056598
   
  
• Analysis of CCR5Delta32 geographic distribution and its correlation with some climatic and geographic factors.
  Limborska SA, Balanovsky OP, Balanovskaya EV, Slominsky PA, Schadrina MI, Livshits LA, Kravchenko SA, Pampuha VM, Khusnutdinova EK, Spitsyn VA
  Hum Hered. 2002
  PubMed ID: 11901272
   
  
• Chemokine receptor genotype is associated with diabetic nephropathy in Japanese with type 2 diabetes.
  Nakajima K, Tanaka Y, Nomiyama T, Ogihara T, Piao L, Sakai K, Onuma T, Kawamori R
  Diabetes. 2002
  PubMed ID: 11756347
   
  
• Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression.
  Tang J, Shelton B, Makhatadze NJ, Zhang Y, Schaen M, Louie LG, Goedert JJ, Seaberg EC, Margolick JB, Mellors J, Kaslow RA
  J Virol. 2002
  PubMed ID: 11752157
   
  
• Up-regulation of CCR5 and CCR6 on distinct subpopulations of antigen-activated CD4+ T lymphocytes.
  Ebert LM, McColl SR
  J Immunol. 2002
  PubMed ID: 11751947
   
  
• Molecular characterization of the CCR 5 gene in seronegative individuals exposed to human immunodeficiency virus (HIV).
  Rugeles MT, Solano F, Díaz FJ, Bedoya VI, Patiño PJ
  J Clin Virol. 2002
  PubMed ID: 11595595
   
  
• Poxvirus infection rapidly activates tyrosine kinase signal transduction.
  Masters J, Hinek AA, Uddin S, Platanias LC, Zeng W, McFadden G, Fish EN
  J Biol Chem. 2001
  PubMed ID: 11591716
   
  
• Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines.
  Bannert N, Craig S, Farzan M, Sogah D, Santo NV, Choe H, Sodroski J
  J Exp Med. 2001
  PubMed ID: 11733580
   
  
• Distribution of HIV-1 resistance-conferring polymorphic alleles SDF-1-3'A, CCR2-64I and CCR5-Delta32 in diverse populations of Andhra Pradesh, South India.
  Ramana GV, Vasanthi A, Khaja M, Su B, Govindaiah V, Jin L, Singh L, Chakraborty R
  J Genet. 2001
  PubMed ID: 11988632
   
  
• Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated region.
  Platt EJ, Kuhmann SE, Rose PP, Kabat D
  J Virol. 2001
  PubMed ID: 11711617
   
  
• Associations of CCR5, CCR2, and stromal cell-derived factor 1 genotypes with human immunodeficiency virus disease progression in patients receiving nucleoside therapy.
  Lathey JL, Tierney C, Chang SY, D'Aquila RT, Bettendorf DM, Alexander HC, Santini CD, Hughes AM, Barroga CF, Spector SA, Landes JE, Hammer SM, Katzenstein DA
  J Infect Dis. 2001
  PubMed ID: 11709782
   
  
• Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptors.
  Pontow S, Ratner L
  J Virol. 2001
  PubMed ID: 11689632
   
  
• CCR5Delta32 and promoter polymorphisms are not correlated with initial virological or immunological treatment response.
  Brumme ZL, Chan KJ, Dong W, Hogg R, O'Shaughnessy MV, Montaner JS, Harrigan PR
  AIDS. 2001
  PubMed ID: 11698699
   
  
• HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling.
  Del Corno M, Liu QH, Schols D, de Clercq E, Gessani S, Freedman BD, Collman RG
  Blood. 2001
  PubMed ID: 11698270
   
  
• Host genetic background at CCR5 chemokine receptor and vitamin D receptor loci and human immunodeficiency virus (HIV) type 1 disease progression among HIV-seropositive injection drug users.
  Barber Y, Rubio C, Fernández E, Rubio M, Fibla J
  J Infect Dis. 2001
  PubMed ID: 11679916
   
  
• Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.
  Navenot JM, Wang ZX, Trent JO, Murray JL, Hu QX, DeLeeuw L, Moore PS, Chang Y, Peiper SC
  J Mol Biol. 2001
  PubMed ID: 11700073
   
  
• Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
  Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie LG, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O'Brien TR, International Meta-Analysis of HIV Host Genetics
  Ann Intern Med. 2001
  PubMed ID: 11694103
   
  
• Genotypes and polymorphisms of mutant CCR5-delta 32, CCR2-64I and SDF1-3' a HIV-1 resistance alleles in indigenous Han Chinese.
  Wang F, Jin L, Lei Z, Shi H, Hong W, Xu D, Jiang J, Wang Y, Zhang B, Liu M, Li Y
  Chin Med J (Engl). 2001
  PubMed ID: 11729511
   
  
• N-linked glycosylation in the V3 region of HIV type 1 surface antigen modulates coreceptor usage in viral infection.
  Li Y, Rey-Cuille MA, Hu SL
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11709091
   
  
• Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype.
  Choe W, Volsky DJ, Potash MJ
  J Virol. 2001
  PubMed ID: 11602715
   
  
• Adverse effect of the CCR5 promoter -2459A allele on HIV-1 disease progression.
  Knudsen TB, Kristiansen TB, Katzenstein TL, Eugen-Olsen J, Copenhagen AIDS Study Group
  J Med Virol. 2001
  PubMed ID: 11596075
   
  
• Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
  Babcock GJ, Mirzabekov T, Wojtowicz W, Sodroski J
  J Biol Chem. 2001
  PubMed ID: 11489906
   
  
• Protection from pulmonary fibrosis in the absence of CCR2 signaling.
  Moore BB, Paine R, Christensen PJ, Moore TA, Sitterding S, Ngan R, Wilke CA, Kuziel WA, Toews GB
  J Immunol. 2001
  PubMed ID: 11591761
   
  
• Length variation of glycoprotein 120 V2 region in relation to biological phenotypes and coreceptor usage of primary HIV type 1 isolates.
  Jansson M, Backström E, Scarlatti G, Björndal A, Matsuda S, Rossi P, Albert J, Wigzell H
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11679153
   
  
• Absence of the HIV-1 protective Delta ccr5 allele in most ethnic populations of India.
  Majumder PP, Dey B
  Eur J Hum Genet. 2001
  PubMed ID: 11781692
   
  
• Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization.
  Kraft K, Olbrich H, Majoul I, Mack M, Proudfoot A, Oppermann M
  J Biol Chem. 2001
  PubMed ID: 11448957
   
  
• Chemokine receptor CCR5 polymorphisms and Chagas' disease cardiomyopathy.
  Calzada JE, Nieto A, Beraún Y, Martín J
  Tissue Antigens. 2001
  PubMed ID: 11703822
   
  
• Biological characterization and chemokine receptor usage of HIV type 1 isolates prevalent in Brazil.
  Ferraro GA, Mello MA, Sutmöller F, Van Weyenbergh J, Shindo N, Galvão-Castro B, Bou-Habib DC, Brazilian Network for HIV Isolation and Characterization
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11559423
   
  
• Distribution of the CCR5 gene 32-basepair deletion in West Europe. A hypothesis about the possible dispersion of the mutation by the Vikings in historical times.
  Lucotte G
  Hum Immunol. 2001
  PubMed ID: 11543895
   
  
• Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp(a) and MCP-1 -2518 G/G genotype in CAD patients.
  Szalai C, Duba J, Prohászka Z, Kalina A, Szabó T, Nagy B, Horváth L, Császár A
  Atherosclerosis. 2001
  PubMed ID: 11500196
   
  
• Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection.
  Marmor M, Sheppard HW, Donnell D, Bozeman S, Celum C, Buchbinder S, Koblin B, Seage GR, HIV Network for Prevention Trials Vaccine Preparedness Protocol Team
  J Acquir Immune Defic Syndr. 2001
  PubMed ID: 11511825
   
  
• Allosteric regulation of CCR5 by guanine nucleotides and HIV-1 envelope.
  Staudinger R, Wang X, Bandrés JC
  Biochem Biophys Res Commun. 2001
  PubMed ID: 11485305
   
  
• Early intermediates in HIV-1 envelope glycoprotein-mediated fusion triggered by CD4 and co-receptor complexes.
  Dimitrov AS, Xiao X, Dimitrov DS, Blumenthal R
  J Biol Chem. 2001
  PubMed ID: 11397808
   
  
• Distribution of CCR5-Delta 32 and CCR2-64I alleles in an Argentine Amerindian population.
  Mangano A, Theiler G, Sala L, Capucchio M, Fainboim L, Sen L
  Tissue Antigens. 2001
  PubMed ID: 11696224
   
  
• [Genotyping of HIV resistant alleles in indigenous Tibetan ethnic group of China: low frequency of CCR5triangle32 and high frequency of CCR2b-64I alleles]
  Hong W, Wang F, Jin L, Xing L, Liu M, Du Q, Lei Z, Li J
  Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001
  PubMed ID: 11484163
   
  
• Human CC chemokine liver-expressed chemokine/CCL16 is a functional ligand for CCR1, CCR2 and CCR5, and constitutively expressed by hepatocytes.
  Nomiyama H, Hieshima K, Nakayama T, Sakaguchi T, Fujisawa R, Tanase S, Nishiura H, Matsuno K, Takamori H, Tabira Y, Yamamoto T, Miura R, Yoshie O
  Int Immunol. 2001
  PubMed ID: 11470772
   
  
• HIV-1 glycoprotein 120 induces the MMP-9 cytopathogenic factor production that is abolished by inhibition of the p38 mitogen-activated protein kinase signaling pathway.
  Missé D, Esteve PO, Renneboog B, Vidal M, Cerutti M, St Pierre Y, Yssel H, Parmentier M, Veas F
  Blood. 2001
  PubMed ID: 11468147
   
  
• RANTES-induced chemokine cascade in dendritic cells.
  Fischer FR, Luo Y, Luo M, Santambrogio L, Dorf ME
  J Immunol. 2001
  PubMed ID: 11466387
   
  
• Protective effect of CCR5 delta 32 heterozygosity is restricted by SDF-1 genotype in children with HIV-1 infection.
  Sei S, Boler AM, Nguyen GT, Stewart SK, Yang QE, Edgerly M, Wood LV, Brouwers P, Venzon DJ
  AIDS. 2001
  PubMed ID: 11504955
   
  
• Polymorphism of CCR5 affecting HIV disease progression in the Japanese population.
  Kageyama S, Mimaya J, Yamada K, Kurimura T, Shiraki K, Research Committee on Prevention of Developing Illness and Therapy for HIV-infected People
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11485615
   
  
• Role of CCR5, CCR2 and SDF-1 gene polymorphisms in a population of HIV-1 infected individuals.
  Mazzucchelli R, Corvasce S, Violin M, Riva C, Bianchi R, Dehò L, Velleca R, Cibella J, Bada M, Moroni M, Galli M, Balotta C
  J Biol Regul Homeost Agents. 2001
  PubMed ID: 11693435
   
  
• Apoptotic effects in primary human umbilical vein endothelial cell cultures caused by exposure to virion-associated and cell membrane-associated HIV-1 gp120.
  Huang MB, Khan M, Garcia-Barrio M, Powell M, Bond VC
  J Acquir Immune Defic Syndr. 2001
  PubMed ID: 11464139
   
  
• Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils.
  Struyf S, Menten P, Lenaerts JP, Put W, D'Haese A, De Clercq E, Schols D, Proost P, Van Damme J
  Eur J Immunol. 2001
  PubMed ID: 11449371
   
  
• The role of the C-C chemokine receptor-5 Delta32 polymorphism in asthma and in the production of regulated on activation, normal T cells expressed and secreted.
  Sandford AJ, Zhu S, Bai TR, Fitzgerald JM, Paré PD
  J Allergy Clin Immunol. 2001
  PubMed ID: 11447384
   
  
• Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES.
  Nardese V, Longhi R, Polo S, Sironi F, Arcelloni C, Paroni R, DeSantis C, Sarmientos P, Rizzi M, Bolognesi M, Pavone V, Lusso P
  Nat Struct Biol. 2001
  PubMed ID: 11427892
   
  
• Target cell populations of human immunodeficiency virus type 1 in peripheral blood lymphocytes with different chemokine receptors at various stages of disease progression.
  Auewarakul P, Sangsiriwut K, Suwanagool S, Wasi C
  J Virol. 2001
  PubMed ID: 11413305
   
  
• CCR5 promoter polymorphisms in a Kenyan perinatal human immunodeficiency virus type 1 cohort: association with increased 2-year maternal mortality.
  John GC, Bird T, Overbaugh J, Nduati R, Mbori-Ngacha D, Rostron T, Dong T, Kostrikis L, Richardson B, Rowland-Jones SL
  J Infect Dis. 2001
  PubMed ID: 11398114
   
  
• N-linked glycosylation sites adjacent to and within the V1/V2 and the V3 loops of dualtropic human immunodeficiency virus type 1 isolate DH12 gp120 affect coreceptor usage and cellular tropism.
  Ogert RA, Lee MK, Ross W, Buckler-White A, Martin MA, Cho MW
  J Virol. 2001
  PubMed ID: 11390601
   
  
• Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.
  Blanpain C, Wittamer V, Vanderwinden JM, Boom A, Renneboog B, Lee B, Le Poul E, El Asmar L, Govaerts C, Vassart G, Doms RW, Parmentier M
  J Biol Chem. 2001
  PubMed ID: 11323418
   
  
• HIV envelope proteins differentially utilize CXCR4 and CCR5 coreceptors for induction of apoptosis.
  Yao Q, Compans RW, Chen C
  Virology. 2001
  PubMed ID: 11414813
   
  
• CC chemokine receptor 5 and renal-transplant survival.
  Fischereder M, Luckow B, Hocher B, Wüthrich RP, Rothenpieler U, Schneeberger H, Panzer U, Stahl RA, Hauser IA, Budde K, Neumayer H, Krämer BK, Land W, Schlöndorff D
  Lancet. 2001
  PubMed ID: 11403814
   
  
• Interactions between HIV-1 gp120, chemokines, and cultured adult microglial cells.
  Albright AV, Martín J, O'Connor M, González-Scarano F
  J Neurovirol. 2001
  PubMed ID: 11517394
   
  
• Genetic variation at the chemokine receptors CCR5/CCR2 in myocardial infarction.
  González P, Alvarez R, Batalla A, Reguero JR, Alvarez V, Astudillo A, Cubero GI, Cortina A, Coto E
  Genes Immun. 2001
  PubMed ID: 11477473
   
  
• A multiethnic study of Delta32ccr5 and ccr2b-V64I allele distribution in four Los Angeles populations.
  Iyer RK, Kim PS, Bando JM, Lu KV, Gregg JP, Grody WW
  Diagn Mol Pathol. 2001
  PubMed ID: 11385319
   
  
• Polymorphism of CC chemokine receptors CCR2 and CCR5 in Crohn's disease.
  Herfarth H, Pollok-Kopp B, Göke M, Press A, Oppermann M
  Immunol Lett. 2001
  PubMed ID: 11377705
   
  
• A homologous naturally occurring mutation in Duffy and CCR5 leading to reduced receptor expression.
  Tamasauskas D, Powell V, Saksela K, Yazdanbakhsh K
  Blood. 2001
  PubMed ID: 11369664
   
  
• Antigenic variation within the CD4 binding site of human immunodeficiency virus type 1 gp120: effects on chemokine receptor utilization.
  Hammond AL, Lewis J, May J, Albert J, Balfe P, McKeating JA
  J Virol. 2001
  PubMed ID: 11356967
   
  
• Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes.
  Cormier EG, Tran DN, Yukhayeva L, Olson WC, Dragic T
  J Virol. 2001
  PubMed ID: 11356961
   
  
• Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor.
  Labrosse B, Treboute C, Brelot A, Alizon M
  J Virol. 2001
  PubMed ID: 11356952
   
  
• Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus.
  Mangano A, Gonzalez E, Dhanda R, Catano G, Bamshad M, Bock A, Duggirala R, Williams K, Mummidi S, Clark RA, Ahuja SS, Dolan MJ, Bologna R, Sen L, Ahuja SK
  J Infect Dis. 2001
  PubMed ID: 11335892
   
  
• CCR5 is the major coreceptor used by HIV-1 subtype C isolates from patients with active tuberculosis.
  Morris L, Cilliers T, Bredell H, Phoswa M, Martin DJ
  AIDS Res Hum Retroviruses. 2001
  PubMed ID: 11429110
   
  
• Chemokine receptor homo- or heterodimerization activates distinct signaling pathways.
  Mellado M, Rodríguez-Frade JM, Vila-Coro AJ, Fernández S, Martín de Ana A, Jones DR, Torán JL, Martínez-A C
  EMBO J. 2001
  PubMed ID: 11350939
   
  
• The synthetic peptide WKYMVm attenuates the function of the chemokine receptors CCR5 and CXCR4 through activation of formyl peptide receptor-like 1.
  Li BQ, Wetzel MA, Mikovits JA, Henderson EE, Rogers TJ, Gong W, Le Y, Ruscetti FW, Wang JM
  Blood. 2001
  PubMed ID: 11342415
   
  
• Human alpha1-acid glycoprotein binds to CCR5 expressed on the plasma membrane of human primary macrophages.
  Atemezem A, Mbemba E, Vassy R, Slimani H, Saffar L, Gattegno L
  Biochem J. 2001
  PubMed ID: 11336643
   
  
• HIV-1 gp120 stimulates the production of beta-chemokines in human peripheral blood monocytes through a CD4-independent mechanism.
  Fantuzzi L, Canini I, Belardelli F, Gessani S
  J Immunol. 2001
  PubMed ID: 11313374
   
  
• Human immunodeficiency virus type 1 clade A and D neurotropism: molecular evolution, recombination, and coreceptor use.
  Zhang K, Hawken M, Rana F, Welte FJ, Gartner S, Goldsmith MA, Power C
  Virology. 2001
  PubMed ID: 11312658
   
  
• The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
  Govaerts C, Blanpain C, Deupi X, Ballet S, Ballesteros JA, Wodak SJ, Vassart G, Pardo L, Parmentier M
  J Biol Chem. 2001
  PubMed ID: 11278962
   
  
• N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization.
  Pollakis G, Kang S, Kliphuis A, Chalaby MI, Goudsmit J, Paxton WA
  J Biol Chem. 2001
  PubMed ID: 11278567
   
  
• A CCR5-dependent novel mechanism for type 1 HIV gp120 induced loss of macrophage cell surface CD4.
  Hewson TJ, Logie JJ, Simmonds P, Howie SE
  J Immunol. 2001
  PubMed ID: 11290759
   
  
• Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells.
  Wong M, Uddin S, Majchrzak B, Huynh T, Proudfoot AE, Platanias LC, Fish EN
  J Biol Chem. 2001
  PubMed ID: 11278738
   
  
• The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity.
  Proudfoot AE, Fritchley S, Borlat F, Shaw JP, Vilbois F, Zwahlen C, Trkola A, Marchant D, Clapham PR, Wells TN
  J Biol Chem. 2001
  PubMed ID: 11116158
   
  
• The CC chemokine receptor 5 delta32 mutation is not associated with inflammatory bowel disease (IBD) in NE England.
  Craggs A, Welfare M, Donaldson PT, Mansfield JC
  Genes Immun. 2001
  PubMed ID: 11393656
   
  
• CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells.
  Singer II, Scott S, Kawka DW, Chin J, Daugherty BL, DeMartino JA, DiSalvo J, Gould SL, Lineberger JE, Malkowitz L, Miller MD, Mitnaul L, Siciliano SJ, Staruch MJ, Williams HR, Zweerink HJ, Springer MS
  J Virol. 2001
  PubMed ID: 11264367
   
  
• Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate.
  Martín J, LaBranche CC, González-Scarano F
  J Virol. 2001
  PubMed ID: 11264346
   
  
• Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5.
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• Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops.
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• Analysis of the CC chemokine receptor 5 (CCR5) delta-32 polymorphism in inflammatory bowel disease.
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• Frequency of CCR5 gene 32-basepair deletion in Chilean HIV-1 infected and non-infected individuals.
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• Polymorphisms in the CCR5 promoter region influence disease progression in perinatally human immunodeficiency virus type 1-infected children.
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• Inhibition of R5X4 dualtropic HIV-1 primary isolates by single chemokine co-receptor ligands.
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• Functional annotation of a full-length mouse cDNA collection.
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• Spectrofluorimetric analysis of CCR5-delta 32 allele using real-time polymerase chain reaction: prevalence in southern Spanish HIV(+) patients and noninfected population.
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• Effect of cocaine on chemokine and CCR-5 gene expression by mononuclear cells from normal donors and HIV-1 infected patients.
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• Role of V3 independent domains on a dualtropic human immunodeficiency virus type 1 (HIV-1) envelope gp120 in CCR5 coreceptor utilization and viral infectivity.
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• Delta 32 mutation of the chemokine-receptor 5 gene in inflammatory bowel disease.
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• A study on the density and distribution of uterine Natural Killer cells at mid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP-1 alpha.
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  J Reprod Immunol. 2001
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• Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140.
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• Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages).
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• [Polymorphisms of chemokine receptor alleles influencing genetic susceptibility to HIV-1 infection in Mongolia population in China]
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• Distribution of three HIV-1 resistance-conferring polymorphisms (SDF1-3'A, CCR2-641, and CCR5-delta32) in global populations.
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  Eur J Hum Genet. 2000
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• CCR5 delta32 deletion and response to highly active antiretroviral therapy in HIV-1-infected patients.
  Guérin S, Meyer L, Theodorou I, Boufassa F, Magierowska M, Goujard C, Rouzioux C, Debré P, Delfraissy JF, SEROCO/HEMOCO Study Group
  AIDS. 2000
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• Chemokine RANTES promoter polymorphism affects risk of both HIV infection and disease progression in the Multicenter AIDS Cohort Study.
  McDermott DH, Beecroft MJ, Kleeberger CA, Al-Sharif FM, Ollier WE, Zimmerman PA, Boatin BA, Leitman SF, Detels R, Hajeer AH, Murphy PM
  AIDS. 2000
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• Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia.
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  Exp Mol Pathol. 2000
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• Desensitization of CXC chemokine receptor 4, mediated by IL-16/CD4, is independent of p56lck enzymatic activity.
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  J Immunol. 2000
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• The N-terminal V3 loop glycan modulates the interaction of clade A and B human immunodeficiency virus type 1 envelopes with CD4 and chemokine receptors.
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• Molecular function of the CD4 D1 domain in coreceptor-mediated entry by HIV type 1.
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  AIDS Res Hum Retroviruses. 2000
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• Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties.
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• Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.
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• RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
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  Genome Res. 2000
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• Heterogeneous spectrum of coreceptor usage among variants within a dualtropic human immunodeficiency virus type 1 primary-isolate quasispecies.
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  J Virol. 2000
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• CCR2-64I polymorphism, syncytium-inducing human immunodeficiency virus strains, and disease progression.
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  J Infect Dis. 2000
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• A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry.
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  J Biol Chem. 2000
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• Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes.
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• A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors.
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  Proc Natl Acad Sci U S A. 2000
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• Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
  Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
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• Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization.
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• Absence of the association with CC chemokine receptor 5 polymorphism in polymyalgia rheumatica.
  Salvarani C, Boiardi L, Timms JM, Silvestri T, Ranzi A, Macchioni PL, Pulsatelli L, di Giovine FS
  Clin Exp Rheumatol. 2000
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• Multiple nonfunctional alleles of CCR5 are frequent in various human populations.
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• Co-receptor usage of HIV-1 primary isolates, viral burden, and CCR5 genotype in mother-to-child HIV-1 transmission.
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  AIDS. 2000
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• [Distribution of HIV resistance CCR5-delta 32, CCR2-64 I and SDF1-3'A alleles and their polymorphisms in the Han population in China]
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• Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection.
  Mañes S, del Real G, Lacalle RA, Lucas P, Gómez-Moutón C, Sánchez-Palomino S, Delgado R, Alcamí J, Mira E, Martínez-A C
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• Evidence for recent selection of the CCR5-delta 32 deletion from differences in its frequency between Ashkenazi and Sephardi Jews.
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  Genes Immun. 2000
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• Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1.
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  J Virol. 2000
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• V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies.
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  J Virol. 2000
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• CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokin
  Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS
  J Exp Med. 2000
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• CCR2+ and CCR5+ CD8+ T cells increase during viral infection and migrate to sites of infection.
  Nansen A, Marker O, Bartholdy C, Thomsen AR
  Eur J Immunol. 2000
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• Consistent and significant inhibition of human immunodeficiency virus type 1 envelope-mediated membrane fusion by beta-chemokines (RANTES) in primary human macrophages.
  Stantchev TS, Broder CC
  J Infect Dis. 2000
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• Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine.
  Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC
  J Immunol. 2000
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• Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.
  Dawson TC, Beck MA, Kuziel WA, Henderson F, Maeda N
  Am J Pathol. 2000
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• gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors.
  Catani MV, Corasaniti MT, Navarra M, Nisticò G, Finazzi-Agrò A, Melino G
  J Neurochem. 2000
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• Interactions of CCR5 and CXCR4 with CD4 and gp120 in human blood monocyte-derived dendritic cells.
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  Exp Mol Pathol. 2000
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• Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines.
  Shen W, Proost P, Li B, Gong W, Le Y, Sargeant R, Murphy PM, Van Damme J, Wang JM
  Biochem Biophys Res Commun. 2000
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• Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120.
  Cormier EG, Persuh M, Thompson DA, Lin SW, Sakmar TP, Olson WC, Dragic T
  Proc Natl Acad Sci U S A. 2000
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• Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120.
  Rizzuto C, Sodroski J
  AIDS Res Hum Retroviruses. 2000
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• Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European Network for In Utero Transmission of HIV-1.
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  J Acquir Immune Defic Syndr. 2000
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• Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs.
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  J Virol. 2000
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• HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.
  Liu QH, Williams DA, McManus C, Baribaud F, Doms RW, Schols D, De Clercq E, Kotlikoff MI, Collman RG, Freedman BD
  Proc Natl Acad Sci U S A. 2000
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• NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding.
  Tugarinov V, Zvi A, Levy R, Hayek Y, Matsushita S, Anglister J
  Structure. 2000
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• HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.
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  AIDS. 2000
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• Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation.
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• HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.
  Vila-Coro AJ, Mellado M, Martín de Ana A, Lucas P, del Real G, Martínez-A C, Rodríguez-Frade JM
  Proc Natl Acad Sci U S A. 2000
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• Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation.
  Agace WW, Roberts AI, Wu L, Greineder C, Ebert EC, Parker CM
  Eur J Immunol. 2000
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• Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5.
  Franchin G, Zybarth G, Dai WW, Dubrovsky L, Reiling N, Schmidtmayerova H, Bukrinsky M, Sherry B
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• Provincial distribution of three HIV-1 resistant polymorphisms (CCR5-Delta32, CCR2-64I, and SDF1-3' A) in China.
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• Modulation of CD4, CXCR-4, and CCR-5 makes human hematopoietic progenitor cell lines infected with human herpesvirus-6 susceptible to human immunodeficiency virus type 1.
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• Involvement of both the V2 and V3 regions of the CCR5-tropic human immunodeficiency virus type 1 envelope in reduced sensitivity to macrophage inflammatory protein 1alpha.
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• Retrovirally mediated IFN-beta transduction of macrophages induces resistance to HIV, correlated with up-regulation of RANTES production and down-regulation of C-C chemokine receptor-5 expression.
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• Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.
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• CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis.
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  Genes Immun. 2000
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• [Frequency of the mutated allele of CCR-5 receptor in HIV-1 positive and negative individuals in the Province of Chaco]
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• Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains.
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• Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.
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  Eur J Immunol. 2000
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• Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.
  Salzwedel K, Smith ED, Dey B, Berger EA
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• Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease.
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• New reporter cell lines to study macrophage-tropic HIV envelope protein-mediated cell-cell fusion.
  Hong YL, Wu LH, Cui M, McMaster G, Hunt SW, Chung FZ
  AIDS Res Hum Retroviruses. 1999
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• Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.
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• Role of HIV-1 Tat and CC chemokine MIP-1alpha in the pathogenesis of HIV associated central nervous system disorders.
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  J Neurovirol. 1999
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• Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates.
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• Relationship between productive HIV-1 infection of macrophages and CCR5 utilization.
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• Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.
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• Small amino acid changes in the V3 loop of human immunodeficiency virus type 2 determines the coreceptor usage for CXCR4 and CCR5.
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• Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans.
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• Peptide T blocks GP120/CCR5 chemokine receptor-mediated chemotaxis.
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• Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
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• In a human lymphomyeloid progenitor cell line (KG-1) HIV-1 gp120 binds to chemokine-receptors CXC-R4 and CCR5, only in the presence of CD4.
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• Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor.
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• Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization.
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• Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication.
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• Effect of extracellular human immunodeficiency virus type 1 glycoprotein 120 on primary human vascular endothelial cell cultures.
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  AIDS Res Hum Retroviruses. 1999
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• Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.
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• CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.
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• Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex.
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