CLTC

Summary Top Help

Gene Description:

clathrin, heavy polypeptide (Hc); clathrin, heavy chain (Hc)

Synonyms:

CHC17, CLTC, CLTCL2, R74732, Hc, CHC, 3110065L21Rik, CLH-17, Cltc

Orthologs:

Human CLTC (protein-coding), Mouse Cltc (protein-coding), Rat Cltc (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr17:57697050..57774317 (77.27 kb) View in Genome Browser

(Mouse) NCBIM37 - chr11:86507853..86571067 (63.21 kb) View in Genome Browser

(Rat) RGSC3.4 - chr10:74976825..75032529 (55.70 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CLTC:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CLTC:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 5

Biocarta: None available

Reactome: 18

NCI-Nature Pathway Interaction Database: 2

Gene Ontology: 25

Publications from PubMed Top Help

Type 1 Diabetes Publications: 2

Publications: 182

Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
Yang W, Thompson JW, Wang Z, Wang L, Sheng H, Foster MW, Moseley MA, Paschen W
J Proteome Res. 2012
PubMed ID: 22082260
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs).
Lopitz-Otsoa F, Rodriguez-Suarez E, Aillet F, Casado-Vela J, Lang V, Matthiesen R, Elortza F, Rodriguez MS
J Proteomics. 2011
PubMed ID: 22178446
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics.
Akimov V, Rigbolt KT, Nielsen MM, Blagoev B
Mol Biosyst. 2011
PubMed ID: 21956701
A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit.
Meyer zu Hörste M, Ströher E, Berchner-Pfannschmidt U, Schmitz-Spanke S, Pink M, Göthert JR, Fischer JW, Gulbins E, Eckstein AK
J Clin Endocrinol Metab. 2011
PubMed ID: 21917865
Clathrin is required for Scar/Wave-mediated lamellipodium formation.
Gautier JJ, Lomakina ME, Bouslama-Oueghlani L, Derivery E, Beilinson H, Faigle W, Loew D, Louvard D, Echard A, Alexandrova AY, Baum B, Gautreau A
J Cell Sci. 2011
PubMed ID: 22010197
Identification of ubiquitinated proteins from human multiple myeloma U266 cells by proteomics.
Jia H, Liu C, Ge F, Xiao C, Lu C, Wang T, He Q
Biomed Environ Sci. 2011
PubMed ID: 22108332
Clathrin heavy chain gene fusions expressed in human cancers: analysis of cellular functions.
Blixt MK, Royle SJ
Traffic. 2011
PubMed ID: 21362119
Human immunodeficiency virus type 1 and related primate lentiviruses engage clathrin through Gag-Pol or Gag.
Popov S, Strack B, Sanchez-Merino V, Popova E, Rosin H, Göttlinger HG
J Virol. 2011
PubMed ID: 21289110
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.
Booth DG, Hood FE, Prior IA, Royle SJ
EMBO J. 2011
PubMed ID: 21297582
Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating.
Böcking T, Aguet F, Harrison SC, Kirchhausen T
Nat Struct Mol Biol. 2011
PubMed ID: 21278753
Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.
Greco TM, Yu F, Guise AJ, Cristea IM
Mol Cell Proteomics. 2011
PubMed ID: 21081666
Endocytosis-independent function of clathrin heavy chain in the control of basal NF-κB activation.
Kim ML, Sorg I, Arrieumerlou C
PLoS One. 2011
PubMed ID: 21364927
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A human MAP kinase interactome.
Bandyopadhyay S, Chiang CY, Srivastava J, Gersten M, White S, Bell R, Kurschner C, Martin CH, Smoot M, Sahasrabudhe S, Barber DL, Chanda SK, Ideker T
Nat Methods. 2010
PubMed ID: 20936779
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes Care. 2010
PubMed ID: 20628086
Plasma membrane contributes to the formation of pre-autophagosomal structures.
Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC
Nat Cell Biol. 2010
PubMed ID: 20639872
Network organization of the human autophagy system.
Behrends C, Sowa ME, Gygi SP, Harper JW
Nature. 2010
PubMed ID: 20562859
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
Lin CH, Hu CK, Shih HM
J Cell Biol. 2010
PubMed ID: 20566684
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia.
Molla-Herman A, Ghossoub R, Blisnick T, Meunier A, Serres C, Silbermann F, Emmerson C, Romeo K, Bourdoncle P, Schmitt A, Saunier S, Spassky N, Bastin P, Benmerah A
J Cell Sci. 2010
PubMed ID: 20427320
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.
Swan LE, Tomasini L, Pirruccello M, Lunardi J, De Camilli P
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20133602
Endocytosis of FcalphaR is clathrin and dynamin dependent, but its cytoplasmic domain is not required.
Peng M, Yin N, Zhang W
Cell Res. 2010
PubMed ID: 19859085
Clostridial glucosylating toxins enter cells via clathrin-mediated endocytosis.
Papatheodorou P, Zamboglou C, Genisyuerek S, Guttenberg G, Aktories K
PLoS One. 2010
PubMed ID: 20498856
Identification of a function-specific mutation of clathrin heavy chain (CHC) required for p53 transactivation.
Ohata H, Ota N, Shirouzu M, Yokoyama S, Yokota J, Taya Y, Enari M
J Mol Biol. 2009
PubMed ID: 19766654
Clathrin-mediated post-Golgi membrane trafficking in the morphogenesis of hepatitis delta virus.
Huang C, Chang SC, Yang HC, Chien CL, Chang MF
J Virol. 2009
PubMed ID: 19793827
Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells.
Ezratty EJ, Bertaux C, Marcantonio EE, Gundersen GG
J Cell Biol. 2009
PubMed ID: 19951918
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium
Am J Hum Genet. 2009
PubMed ID: 19913121
Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway.
Hägele H, Allam R, Pawar RD, Reichel CA, Krombach F, Anders HJ
Am J Pathol. 2009
PubMed ID: 19834059
Identification of novel spartin-interactors shows spartin is a multifunctional protein.
Milewska M, McRedmond J, Byrne PC
J Neurochem. 2009
PubMed ID: 19765186
Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.
Matafora V, D'Amato A, Mori S, Blasi F, Bachi A
Mol Cell Proteomics. 2009
PubMed ID: 19596686
GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression.
Shimizu H, Nagamori I, Yabuta N, Nojima H
J Cell Sci. 2009
PubMed ID: 19654208
Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.
Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I
FASEB J. 2009
PubMed ID: 19423638
Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.
Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O
Proc Natl Acad Sci U S A. 2009
PubMed ID: 19666558
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.
Hood FE, Royle SJ
J Cell Sci. 2009
PubMed ID: 19509056
Large-scale proteomics analysis of the human kinome.
Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H
Mol Cell Proteomics. 2009
PubMed ID: 19369195
Characterization of clathrin and Syk interaction upon Shiga toxin binding.
Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K
Cell Signal. 2009
PubMed ID: 19289168
A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism.
Vassilopoulos S, Esk C, Hoshino S, Funke BH, Chen CY, Plocik AM, Wright WE, Kucherlapati R, Brodsky FM
Science. 2009
PubMed ID: 19478182
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Cross-linking of FcepsilonRI causes Ca2+ mobilization via a sphingosine kinase pathway in a clathrin-dependent manner.
Ryu SD, Lee HS, Suk HY, Park CS, Choi OH
Cell Calcium. 2009
PubMed ID: 18675457
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
Sci Signal. 2009
PubMed ID: 19690332
SNX4 in complex with clathrin and dynein: implications for endosome movement.
Skånland SS, Wälchli S, Brech A, Sandvig K
PLoS One. 2009
PubMed ID: 19529763
Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells.
Sarnataro D, Caputo A, Casanova P, Puri C, Paladino S, Tivodar SS, Campana V, Tacchetti C, Zurzolo C
PLoS One. 2009
PubMed ID: 19503793
The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand.
Chakrabandhu K, Huault S, Garmy N, Fantini J, Stebe E, Mailfert S, Marguet D, Hueber AO
Cell Death Differ. 2008
PubMed ID: 18670435
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions.
McFarland MA, Ellis CE, Markey SP, Nussbaum RL
Mol Cell Proteomics. 2008
PubMed ID: 18614564
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A
Genome Res. 2008
PubMed ID: 18799693
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
Double-membrane gap junction internalization requires the clathrin-mediated endocytic machinery.
Gumpert AM, Varco JS, Baker SM, Piehl M, Falk MM
FEBS Lett. 2008
PubMed ID: 18656476
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
Mol Cell. 2008
PubMed ID: 18691976
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.
Yamauchi T, Ishidao T, Nomura T, Shinagawa T, Tanaka Y, Yonemura S, Ishii S
EMBO J. 2008
PubMed ID: 18548008
FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes.
Jarczowski F, Fischer G, Edlich F
Biochemistry. 2008
PubMed ID: 18529014
Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.
Forsman A, Rüetschi U, Ekholm J, Rymo L
J Proteome Res. 2008
PubMed ID: 18457437
Monomeric but not trimeric clathrin heavy chain regulates p53-mediated transcription.
Ohmori K, Endo Y, Yoshida Y, Ohata H, Taya Y, Enari M
Oncogene. 2008
PubMed ID: 17952123
Regulation of clathrin-mediated endocytosis by p53.
Endo Y, Sugiyama A, Li SA, Ohmori K, Ohata H, Yoshida Y, Shibuya M, Takei K, Enari M, Taya Y
Genes Cells. 2008
PubMed ID: 18363968
Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB5 toxin that targets the endoplasmic reticulum chaperone BiP.
Chong DC, Paton JC, Thorpe CM, Paton AW
Cell Microbiol. 2008
PubMed ID: 18042253
Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
Ballif BA, Carey GR, Sunyaev SR, Gygi SP
J Proteome Res. 2008
PubMed ID: 18034455
A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction.
Rapoport I, Boll W, Yu A, Böcking T, Kirchhausen T
Mol Biol Cell. 2008
PubMed ID: 17978091
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
Cell. 2007
PubMed ID: 18083107
The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities.
Collin G, Franco M, Simon V, Bénistant C, Roche S
Mol Cell Biol. 2007
PubMed ID: 17785434
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation.
Shenoy SK, Barak LS, Xiao K, Ahn S, Berthouze M, Shukla AK, Luttrell LM, Lefkowitz RJ
J Biol Chem. 2007
PubMed ID: 17666399
Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR
Biochem J. 2007
PubMed ID: 17461779
The retromer complex and clathrin define an early endosomal retrograde exit site.
Popoff V, Mardones GA, Tenza D, Rojas R, Lamaze C, Bonifacino JS, Raposo G, Johannes L
J Cell Sci. 2007
PubMed ID: 17550971
Synaptotagmin I binds intestinal epithelial NHE3 and mediates cAMP- and Ca2+-induced endocytosis by recruitment of AP2 and clathrin.
Musch MW, Arvans DL, Walsh-Reitz MM, Uchiyama K, Fukuda M, Chang EB
Am J Physiol Gastrointest Liver Physiol. 2007
PubMed ID: 17307723
Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells.
Tu LC, Yan X, Hood L, Lin B
Mol Cell Proteomics. 2007
PubMed ID: 17220478
Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling.
Na J, Lykke-Andersen K, Torres Padilla ME, Zernicka-Goetz M
Dev Biol. 2007
PubMed ID: 17005174
The full-ORF clone resource of the German cDNA Consortium.
Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blöcker H, Heubner D, Hoerlein A, Michel G, Wedler H, Köhrer K, Ottenwälder B, Poustka A, Wiemann S, Schupp I
BMC Genomics. 2007
PubMed ID: 17974005
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
A role for clathrin in reassembly of the Golgi apparatus.
Radulescu AE, Siddhanta A, Shields D
Mol Biol Cell. 2007
PubMed ID: 17065556
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF
J Proteome Res. 2006
PubMed ID: 17081065
Identification of 14-3-3epsilon substrates from embryonic murine brain.
Ballif BA, Cao Z, Schwartz D, Carraway KL, Gygi SP
J Proteome Res. 2006
PubMed ID: 16944949
Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.
Schmid EM, Ford MG, Burtey A, Praefcke GJ, Peak-Chew SY, Mills IG, Benmerah A, McMahon HT
PLoS Biol. 2006
PubMed ID: 16903783
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.
Nakamura M, Tanaka N, Kitamura N, Komada M
Genes Cells. 2006
PubMed ID: 16716190
SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network.
Natsume W, Tanabe K, Kon S, Yoshida N, Watanabe T, Torii T, Satake M
Mol Biol Cell. 2006
PubMed ID: 16571680
Requirement of clathrin heavy chain for p53-mediated transcription.
Enari M, Ohmori K, Kitabayashi I, Taya Y
Genes Dev. 2006
PubMed ID: 16618797
Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.
Giri DK, Ali-Seyed M, Li LY, Lee DF, Ling P, Bartholomeusz G, Wang SC, Hung MC
Mol Cell Biol. 2005
PubMed ID: 16314522
A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors.
Urs NM, Jones KT, Salo PD, Severin JE, Trejo J, Radhakrishna H
J Cell Sci. 2005
PubMed ID: 16263766
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
Differential control of clathrin subunit dynamics measured with EW-FRAP microscopy.
Loerke D, Wienisch M, Kochubey O, Klingauf J
Traffic. 2005
PubMed ID: 16138905
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network.
Choudhury R, Diao A, Zhang F, Eisenberg E, Saint-Pol A, Williams C, Konstantakopoulos A, Lucocq J, Johannes L, Rabouille C, Greene LE, Lowe M
Mol Biol Cell. 2005
PubMed ID: 15917292
Clathrin-dependent and clathrin-independent retrieval of synaptic vesicles in retinal bipolar cells.
Jockusch WJ, Praefcke GJ, McMahon HT, Lagnado L
Neuron. 2005
PubMed ID: 15953416
Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells.
Merrifield CJ, Perrais D, Zenisek D
Cell. 2005
PubMed ID: 15907472
Clathrin is required for the function of the mitotic spindle.
Royle SJ, Bright NA, Lagnado L
Nature. 2005
PubMed ID: 15858577
Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo.
Chen CY, Brodsky FM
J Biol Chem. 2005
PubMed ID: 15533940
Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Moran AE, Hunt DH, Javid SH, Redston M, Carothers AM, Bertagnolli MM
J Biol Chem. 2004
PubMed ID: 15294912
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Büssow K, Buessow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE
Mol Cell. 2004
PubMed ID: 15383276
Purification and identification of protein-tyrosine kinase-binding proteins using synthetic phosphopeptides as affinity reagents.
Wilhelmsen K, Copp J, Glenn G, Hoffman RC, Tucker P, van der Geer P
Mol Cell Proteomics. 2004
PubMed ID: 15215307
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T
Curr Biol. 2004
PubMed ID: 15324660
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
Meek SE, Lane WS, Piwnica-Worms H
J Biol Chem. 2004
PubMed ID: 15161933
Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.
Towler MC, Gleeson PA, Hoshino S, Rahkila P, Manalo V, Ohkoshi N, Ordahl C, Parton RG, Brodsky FM
Mol Biol Cell. 2004
PubMed ID: 15133132
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference.
Huang F, Khvorova A, Marshall W, Sorkin A
J Biol Chem. 2004
PubMed ID: 14985334
T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization.
Crotzer VL, Mabardy AS, Weiss A, Brodsky FM
J Exp Med. 2004
PubMed ID: 15067034
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nat Genet. 2004
PubMed ID: 14702039
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin.
Yamakami M, Yoshimori T, Yokosawa H
J Biol Chem. 2003
PubMed ID: 14563850
Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.
Jackson M, Baird JW, Nichols J, Wilkie R, Ansell JD, Graham G, Forrester LM
Dev Dyn. 2003
PubMed ID: 14648851
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell. 2003
PubMed ID: 14651853
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components.
Lundmark R, Carlsson SR
J Biol Chem. 2003
PubMed ID: 12952949
Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells.
Hinrichsen L, Harborth J, Andrees L, Weber K, Ungewickell EJ
J Biol Chem. 2003
PubMed ID: 12960147
Clathrin-mediated endocytosis in AP-2-depleted cells.
Motley A, Bright NA, Seaman MN, Robinson MS
J Cell Biol. 2003
PubMed ID: 12952941
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Molecular and functional characterization of clathrin- and AP-2-binding determinants within a disordered domain of auxilin.
Scheele U, Alves J, Frank R, Duwel M, Kalthoff C, Ungewickell E
J Biol Chem. 2003
PubMed ID: 12732633
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J
Nat Biotechnol. 2003
PubMed ID: 12665801
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Aizawa H, Yuasa S, Nakajima D, Nagase T, Ohara O, Koga H
DNA Res. 2003
PubMed ID: 12693553
Adaptor and clathrin exchange at the plasma membrane and trans-Golgi network.
Wu X, Zhao X, Puertollano R, Bonifacino JS, Eisenberg E, Greene LE
Mol Biol Cell. 2003
PubMed ID: 12589051
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic Acids Res. 2003
PubMed ID: 12520002
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
A gene expression map of human chromosome 21 orthologues in the mouse.
Gitton Y, Dahmane N, Baik S, Ruiz i Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, HSA21 expression map initiative
Nature. 2002
PubMed ID: 12466855
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans.
Chen CY, Reese ML, Hwang PK, Ota N, Agard D, Brodsky FM
EMBO J. 2002
PubMed ID: 12426379
ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.
He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC
J Biol Chem. 2002
PubMed ID: 12221107
Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.
Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ
Mol Biol Cell. 2002
PubMed ID: 12429846
Mixed lineage kinase 2 interacts with clathrin and influences clathrin-coated vesicle trafficking.
Akbarzadeh S, Ji H, Frecklington D, Marmy-Conus N, Mok YF, Bowes L, Devereux L, Linsenmeyer M, Simpson RJ, Dorow DS
J Biol Chem. 2002
PubMed ID: 12105200
Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics.
Wasiak S, Legendre-Guillemin V, Puertollano R, Blondeau F, Girard M, de Heuvel E, Boismenu D, Bell AW, Bonifacino JS, McPherson PS
J Cell Biol. 2002
PubMed ID: 12213833
HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.
Legendre-Guillemin V, Metzler M, Charbonneau M, Gan L, Chopra V, Philie J, Hayden MR, McPherson PS
J Biol Chem. 2002
PubMed ID: 11889126
Regulation of arrestin-3 phosphorylation by casein kinase II.
Kim YM, Barak LS, Caron MG, Benovic JL
J Biol Chem. 2002
PubMed ID: 11877451
Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin.
Ivings L, Pennington SR, Jenkins R, Weiss JL, Burgoyne RD
Biochem J. 2002
PubMed ID: 11964161
The Cdc42 target ACK2 interacts with sorting nexin 9 (SH3PX1) to regulate epidermal growth factor receptor degradation.
Lin Q, Lo CG, Cerione RA, Yang W
J Biol Chem. 2002
PubMed ID: 11799118
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.
Di Paolo G, Sankaranarayanan S, Wenk MR, Daniell L, Perucco E, Caldarone BJ, Flavell R, Picciotto MR, Ryan TA, Cremona O, De Camilli P
Neuron. 2002
PubMed ID: 11879655
Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors.
Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS
Mol Cell Biol. 2001
PubMed ID: 11604514
HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.
Metzler M, Legendre-Guillemin V, Gan L, Chopra V, Kwok A, McPherson PS, Hayden MR
J Biol Chem. 2001
PubMed ID: 11517213
Multiple interactions of auxilin 1 with clathrin and the AP-2 adaptor complex.
Scheele U, Kalthoff C, Ungewickell E
J Biol Chem. 2001
PubMed ID: 11470803
Hrs recruits clathrin to early endosomes.
Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H
EMBO J. 2001
PubMed ID: 11532964
Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Piao Y, Ko NT, Lim MK, Ko MS
Genome Res. 2001
PubMed ID: 11544199
Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29.
Rotem-Yehudar R, Galperin E, Horowitz M
J Biol Chem. 2001
PubMed ID: 11423532
The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.
Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, Gauss C, Sathasivam K, Bates GP, Lehrach H, Wanker EE
Hum Mol Genet. 2001
PubMed ID: 11532990
Gamma subunit of the AP-1 adaptor complex binds clathrin: implications for cooperative binding in coated vesicle assembly.
Doray B, Kornfeld S
Mol Biol Cell. 2001
PubMed ID: 11451993
Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.
Zhu Y, Doray B, Poussu A, Lehto VP, Kornfeld S
Science. 2001
PubMed ID: 11387476
The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors.
Teo M, Tan L, Lim L, Manser E
J Biol Chem. 2001
PubMed ID: 11278436
The GGAs promote ARF-dependent recruitment of clathrin to the TGN.
Puertollano R, Randazzo PA, Presley JF, Hartnell LM, Bonifacino JS
Cell. 2001
PubMed ID: 11301005
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor.
Yano H, Lee FS, Kong H, Chuang J, Arevalo J, Perez P, Sung C, Chao MV
J Neurosci. 2001
PubMed ID: 11157096
Three ways to make a vesicle.
Kirchhausen T
Nat Rev Mol Cell Biol. 2000
PubMed ID: 11252894
A conserved clathrin assembly motif essential for synaptic vesicle endocytosis.
Morgan JR, Prasad K, Hao W, Augustine GJ, Lafer EM
J Neurosci. 2000
PubMed ID: 11102472
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation.
Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA
J Neurosci. 2000
PubMed ID: 10908605
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.
Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG
Nat Neurosci. 2000
PubMed ID: 10862698
Epsin binds to clathrin by associating directly with the clathrin-terminal domain. Evidence for cooperative binding through two discrete sites.
Drake MT, Downs MA, Traub LM
J Biol Chem. 2000
PubMed ID: 10692452
Secretory protein trafficking and organelle dynamics in living cells.
Lippincott-Schwartz J, Roberts TH, Hirschberg K
Annu Rev Cell Dev Biol. 2000
PubMed ID: 11031247
An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.
Engqvist-Goldstein AE, Kessels MM, Chopra VS, Hayden MR, Drubin DG
J Cell Biol. 1999
PubMed ID: 10613908
A requirement for ankyrin binding to clathrin during coated pit budding.
Michaely P, Kamal A, Anderson RG, Bennett V
J Biol Chem. 1999
PubMed ID: 10585476
The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.
Rosenthal JA, Chen H, Slepnev VI, Pellegrini L, Salcini AE, Di Fiore PP, De Camilli P
J Biol Chem. 1999
PubMed ID: 10567358
Signaling via Src family kinases is required for normal internalization of the receptor c-Kit.
Broudy VC, Lin NL, Liles WC, Corey SJ, O'Laughlin B, Mou S, Linnekin D
Blood. 1999
PubMed ID: 10477727
Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.
Tebar F, Bohlander SK, Sorkin A
Mol Biol Cell. 1999
PubMed ID: 10436022
Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells.
Hussain NK, Yamabhai M, Ramjaun AR, Guy AM, Baranes D, O'Bryan JP, Der CJ, Kay BK, McPherson PS
J Biol Chem. 1999
PubMed ID: 10336464
Clathrin self-assembly is mediated by a tandemly repeated superhelix.
Ybe JA, Brodsky FM, Hofmann K, Lin K, Liu SH, Chen L, Earnest TN, Fletterick RJ, Hwang PK
Nature. 1999
PubMed ID: 10360576
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.
Turner CE, Brown MC, Perrotta JA, Riedy MC, Nikolopoulos SN, McDonald AR, Bagrodia S, Thomas S, Leventhal PS
J Cell Biol. 1999
PubMed ID: 10330411
The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.
Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10097102
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker.
ter Haar E, Musacchio A, Harrison SC, Kirchhausen T
Cell. 1998
PubMed ID: 9827808
Role of phosphorylation in regulation of the assembly of endocytic coat complexes.
Slepnev VI, Ochoa GC, Butler MH, Grabs D, De Camilli P
Science. 1998
PubMed ID: 9694653
Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites.
Ramjaun AR, McPherson PS
J Neurochem. 1998
PubMed ID: 9603201
Association of the AP-3 adaptor complex with clathrin.
Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS
Science. 1998
PubMed ID: 9545220
In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly.
Witke W, Podtelejnikov AV, Di Nardo A, Sutherland JD, Gurniak CB, Dotti C, Mann M
EMBO J. 1998
PubMed ID: 9463375
Nef-mediated clathrin-coated pit formation.
Foti M, Mangasarian A, Piguet V, Lew DP, Krause KH, Trono D, Carpentier JL
J Cell Biol. 1997
PubMed ID: 9314527
Clathrin interacts specifically with amphiphysin and is displaced by dynamin.
McMahon HT, Wigge P, Smith C
FEBS Lett. 1997
PubMed ID: 9280305
Identification and characterization of a nerve terminal-enriched amphiphysin isoform.
Ramjaun AR, Micheva KD, Bouchelet I, McPherson PS
J Biol Chem. 1997
PubMed ID: 9195986
Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.
Goodman OB, Krupnick JG, Gurevich VV, Benovic JL, Keen JH
J Biol Chem. 1997
PubMed ID: 9169477
Normalization and subtraction: two approaches to facilitate gene discovery.
Bonaldo MF, Lennon G, Soares MB
Genome Res. 1996
PubMed ID: 8889548
Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.
Kedra D, Peyrard M, Fransson I, Collins JE, Dunham I, Roe BA, Dumanski JP
Hum Mol Genet. 1996
PubMed ID: 8733129
Isolation and characterization of distinct domains of sarcolemma and T-tubules from rat skeletal muscle.
Muñoz P, Rosemblatt M, Testar X, Palacín M, Zorzano A
Biochem J. 1995
PubMed ID: 7536412
Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement).
Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S
DNA Res. 1994
PubMed ID: 7584028
Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.
Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S
DNA Res. 1994
PubMed ID: 7584026
Interaction of vinculin with the clathrin heavy chain.
Fausser JL, Ungewickell E, Ruch JV, Lesot H
J Biochem. 1993
PubMed ID: 8276759
Possible involvement of clathrin in neuritogenesis induced by a protease inhibitor (benzyloxycarbonyl-Leu-Leu-Leu-aldehyde) in PC12 cells.
Saito Y, Tsubuki S, Ito H, Ohmi-Imajo S, Kawashima S
J Biochem. 1992
PubMed ID: 1490999
Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia.
Murphy JE, Keen JH
J Biol Chem. 1992
PubMed ID: 1587861
Spinal cord repair: future directions.
Fawcett JW
Paraplegia. 1992
PubMed ID: 1589293
Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter.
Dodge GR, Kovalszky I, McBride OW, Yi HF, Chu ML, Saitta B, Stokes DG, Iozzo RV
Genomics. 1991
PubMed ID: 1765375
Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3.
Scarmato P, Kirchhausen T
J Biol Chem. 1990
PubMed ID: 2406259
Insulin stimulates the assembly of cytosolic clathrin onto adipocyte plasma membranes.
Corvera S
J Biol Chem. 1990
PubMed ID: 2154445
A highly phosphorylated subpopulation of insulin-like growth factor II/mannose 6-phosphate receptors is concentrated in a clathrin-enriched plasma membrane fraction.
Corvera S, Folander K, Clairmont KB, Czech MP
Proc Natl Acad Sci U S A. 1988
PubMed ID: 2971973
Clathrin heavy chain: molecular cloning and complete primary structure.
Kirchhausen T, Harrison SC, Chow EP, Mattaliano RJ, Ramachandran KL, Smart J, Brosius J
Proc Natl Acad Sci U S A. 1987
PubMed ID: 3480512
The association of clathrin fragments with coated vesicle membranes.
Hanspal M, Luna E, Branton D
J Biol Chem. 1984
PubMed ID: 6147350

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	1213	67300	54241
EnsEMBL Gene(s)	ENSG00000141367	ENSMUSG00000047126	ENSRNOG00000004291
Unigene	Hs.491351	Mm.479526	Rn.3589
Homologene	CLTC	Cltc	Cltc
OMIM	118955	N/A	N/A
GeneCards	CLTC	N/A	N/A
Beta Cell Genomics	DT.100672405 DT.120930523 DT.219977 DT.91887587 DT.95338490	DT.101196375 DT.496029 DT.97356413 DT.99848317	N/A
Reactome	Q00610	N/A	N/A
Plasma Peptide Atlas	ENSP00000263200	N/A	N/A
WikiGenes	1213	67300	54241

External resources from NIDDK Consortium Interconnectivity Network Top Help

Relevant resources:

View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
CLTC	TANK	MINT, IntAct	empirical	14743216
CLTC	TOM1	HPRD	empirical	14563850
CLTC	TNK2	HPRD, MINT	empirical	11278436 16137687
CLTC	NDRG1	HPRD, IntAct	empirical	17220478
CLTC	RIPK3	MINT, IntAct	empirical	14743216
CLTC	STX1B	IntAct	empirical	19562802
CLTC	GABARAP	IntAct	empirical	20562859
CLTC	GABARAPL2	IntAct	empirical	20562859
CLTC	CHUK	IntAct	empirical	14743216
CLTC	LRRK2	IntAct	empirical	21307259
CLTC	CLTA	HPRD, Reactome	empirical	12426379 2406259
CLTC	CLTB	HPRD	empirical	12426379 15533940
CLTC	CLTC	HPRD	empirical	12952949 12426379 11532990
CLTC	MAP3K8	IntAct	empirical	14743216
CLTC	DYNLL2	Sanger Interaction Map	predicted	15345047
CLTC	AP1B1	HPRD	empirical	11451993
CLTC	AP1G1	HPRD	empirical	11451993
CLTC	DLG4	IntAct	empirical	19562802 19455133
CLTC	EP300	IntAct	empirical	21988832
CLTC	ERBB2	IntAct	empirical	16314522
CLTC	ESR1	IntAct	empirical	21182205
CLTC	EPN2	HPRD, MINT	empirical	10567358 10336464
CLTC	GGA2	HPRD, MINT	empirical	11301005 11387476
CLTC	SPG20	IntAct	empirical	19765186
CLTC	TAB2	MINT, IntAct	empirical	14743216
CLTC	GGA3	HPRD	empirical	11301005
CLTC	RPGRIP1L	IntAct	empirical	21565611
CLTC	CD2AP	IntAct	empirical	20360068
CLTC	GABARAPL1	IntAct	empirical	20562859
CLTC	XRCC6	HPRD, MINT, IntAct	empirical	15383276
CLTC	GAK	HPRD	empirical	12732633
CLTC	GGA1	HPRD	empirical	11301005
CLTC	LDLRAP1	HPRD	empirical	12221107
CLTC	AMPH	HPRD	empirical	9280305 9603201 9195986
CLTC	GRIA1	IntAct	empirical	19562802
CLTC	GRIN1	HPRD, MINT, IntAct	empirical	10862698 16635246
CLTC	GRIN2B	IntAct	empirical	10862698 16635246
CLTC	GRIN2D	HPRD	empirical	10862698
CLTC	NR3C1	IntAct	empirical	20195357
CLTC	EPN1	HPRD, MINT	empirical	10692452
CLTC	HIP1	HPRD, MINT	empirical	11532990 15383276
CLTC	HLA-C	IntAct	empirical	17353931
CLTC	IKBKB	MINT, IntAct	empirical	14743216
CLTC	KIT	HPRD	empirical	10477727
CLTC	KPNB1	IntAct	empirical	16314522
CLTC	ARR3	HPRD	empirical	9827808 11877451
CLTC	ARRB1	HPRD, IntAct	empirical	9169477 17620599
CLTC	ARRB2	HPRD	empirical	10097102 17666399
CLTC	MCC	IntAct	empirical	17353931
CLTC	MAP3K3	MINT, IntAct	empirical	14743216
CLTC	MAP3K10	HPRD	empirical	12105200
CLTC	MYB	MINT	empirical	18548008
CLTC	NFKB1	MINT	empirical	14743216
CLTC	NFKB2	MINT, IntAct	empirical	14743216
CLTC	NFKBIA	IntAct	empirical	14743216
CLTC	NFKBIB	IntAct	empirical	14743216
CLTC	NFKBIE	IntAct	empirical	14743216
CLTC	OCRL	HPRD, MINT	empirical	15917292 16902405
CLTC	SNX9	HPRD	empirical	11799118 12952949
CLTC	NCKIPSD	MINT	empirical	16999739
CLTC	ARMCX3	HPRD, MINT, IntAct	empirical	16169070
CLTC	PFN1	BioGRID	empirical	9463375
CLTC	PRKAB1	IntAct	empirical	17353931
CLTC	PRKACA	IntAct	empirical	20936779
CLTC	SCYL2	HPRD	empirical	1589293
CLTC	MAPK3	MINT	empirical	19935650
CLTC	MAPK13	IntAct	empirical	19135240
CLTC	PXN	HPRD	empirical	10330411
CLTC	QARS	IntAct	empirical	21988832
CLTC	REL	IntAct	empirical	14743216
CLTC	RELA	MINT, IntAct	empirical	14743216
CLTC	RELB	MINT, IntAct	empirical	14743216
CLTC	RPA2	Sanger Interaction Map	predicted	15345047
CLTC	BCR	MINT	empirical	15494376
CLTC	RPS9	IntAct	empirical	17461779
CLTC	SLC2A4	IntAct	empirical	16396496
CLTC	SUMO3	BioGRID	empirical	22082260
CLTC	SNAP25	IntAct	empirical	19562802
CLTC	SNCA	IntAct	empirical	18614564
CLTC	STX1A	IntAct	empirical	19562802
CLTC	MAP3K7	MINT, IntAct	empirical	14743216
CLTC	TFAP2A	HPRD	empirical	1587861
CLTC	TFE3	IntAct	empirical	17353931
CLTC	TNFRSF1A	MINT, IntAct	empirical	14743216
CLTC	TNFRSF1B	MINT, IntAct	empirical	14743216
CLTC	TRAF2	MINT, IntAct	empirical	14743216
CLTC	TRPC5	Sanger Interaction Map	predicted	15345047
CLTC	UBE2I	IntAct	empirical	20936779
CLTC	VCL	HPRD	empirical	8276759
CLTC	YWHAB	IntAct	empirical	16635246
CLTC	YWHAE	BioGRID	empirical	16944949
CLTC	YWHAG	HPRD	empirical	15324660
CLTC	YWHAZ	MINT, IntAct	empirical	15161933 19562802
CLTC	C10orf88	HPRD, IntAct	empirical	16169070
CLTC	AP3B2	HPRD	empirical	9545220
CLTC	CAMK2A	IntAct	empirical	19562802
CLTC	MAP1LC3B	IntAct	empirical	20562859
CLTC	PICALM	HPRD, MIPS	empirical	10436022
CLTC	TBC1D10A	Sanger Interaction Map	predicted	15345047
CLTC	NCALD	HPRD, BioGRID	empirical	11964161
CLTC	MAP1LC3A	IntAct	empirical	20562859
CLTC	IKBKG	MINT, IntAct	empirical	14743216
CLTC	AP3B1	HPRD	empirical	9545220
CLTC	CASK	IntAct	empirical	19022416
CLTC	TRADD	MINT, IntAct	empirical	14743216
CLTC	EED	IntAct	empirical	20064375
CLTC	HIP1R	HPRD	empirical	11889126
CLTC	HGS	HPRD	empirical	11532964
CLTC	PTTG1	IntAct	empirical	20360068
CLTC	IKBKE	MINT, IntAct	empirical	14743216 17353931
CLTC	CLINT1	HPRD, MINT	empirical	12429846 14675752
CLTC	DNAJC6	HPRD	empirical	11470803