TAGAP

  Summary from T1DBase   Top   Help
Gene Description:   T-cell activation Rho GTPase-activating protein; T-cell activation RhoGTPase activating protein
Synonyms:   FLJ39771, TAGAP, TAGAP1, 2610315E15Rik, ARHGAP47, Tagap, MGC27381, FLJ32631, MGC31468, IDDM21, MGC133247
Orthologs:   Human TAGAP (protein-coding), Mouse Tagap (protein-coding), Rat Tagap (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1 Mouse: 2 Rat: 1
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
6q25.3 Human chr6:159317512..159526689 0.21 18 rs1738074
expander Linkage Regions: Available
expander Other Regions: Available
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr6:159455500..159466184 (10.68 kb)  View in Genome Browser
expander (Mouse) NCBIM37 - chr17:8118865..8127762 (8.90 kb)  View in Genome Browser
expander (Rat) RGSC3.4 - chr1:41385839..41392522 (6.68 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
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expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern Not Detected Low High High High High High Moderate HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
Interactions: 0
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
KEGG Network: None available
Biocarta: None available
expander Reactome: 2
NCI-Nature Pathway Interaction Database: None available
expander Gene Ontology: 6
  Publications   Top   Help
expander Type 1 Diabetes Publications: 4
expander Publications: 24
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
Organism Phenotype Resources
Mouse MGI:3615484 IKMC
  External Links   Top   Help
  Human Mouse Rat
Entrez Gene 117289 72536 308097
EnsEMBL Gene(s) ENSG00000164691 ENSMUSG00000033450 ENSMUSG00000079571 N/A
Unigene Hs.529984 Mm.119680 N/A
Homologene TAGAP Tagap Tagap
OMIM 609667 N/A N/A
GeneCards TAGAP N/A N/A
Beta Cell Genomics DT.100776153 DT.40125502 DT.40308071 DT.40312762 DT.97772033 DT.101371232 DT.531149 N/A
Reactome Q8N103 N/A N/A
Plasma Peptide Atlas N/A N/A N/A
MGI N/A MGI:3615484 N/A
WikiGenes 117289 72536 308097
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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