AP4B1

  Summary from T1DBase   Top   Help
Gene Description:   adaptor-related protein complex AP-4, beta 1; adaptor-related protein complex 4, beta 1 subunit
Synonyms:   1810038H16Rik, BETA-4, AV004952, Ap4b1, Ap4b4, CPSQ5, AP4B1
Orthologs:   Human AP4B1 (protein-coding), Mouse Ap4b1 (protein-coding), Rat Ap4b1 (protein-coding)
 
expander Sources
  Regions of Interest Overlapping this feature from T1DBase   Top   Help
Regions Overlapping this Feature:  Human: 1 Mouse: 2 Rat: 4
expander Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Region Species Chromosomal Location Mb Number of genes Marker
1p13.2 Human chr1:113818477..114658477 0.84 73 rs2476601
expander Linkage Regions: Available
expander Other Regions: Available
  Gene Overview from T1DBase   Top   Help
expander (Human) GRCh37 - chr1:114437370..114447823 (10.45 kb)  View in Genome Browser
expander (Mouse) NCBIM37 - chr3:103613440..103625948 (12.51 kb)  View in Genome Browser
expander (Rat) RGSC3.4 - chr2:199034351..199046334 (11.98 kb)  View in Genome Browser
  Beta Cell Gene Atlas from T1DBase   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
Human Mouse Rat
ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas
 
 
 
no data  
 
 
 
 
 
 
 
 
expander Expression Legend
  Tissue Expression   Top   Help

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
 
/expression/atlas-PB_CD14+_Monocytes.png /expression/atlas-PB_CD56+_NK_Cells.png /expression/atlas-PB_CD19-_B_Cells.png /expression/atlas-PB_CD4+_T_Cells.png /expression/atlas-PB_CD8+_T_Cells.png /expression/atlas-PB_BDCA4+_Dendritic_Cells.png /expression/atlas-721_B_Lymphoblasts.png /expression/atlas-Lymph_Node.png /expression/atlas-Thymus.png /expression/atlas-Salivary_Gland.png /expression/atlas-Bone_Marrow.png /expression/atlas-BM_CD34+.png /expression/atlas-Heart.png /expression/atlas-Skeletal_Muscle.png /expression/atlas-Kidney.png /expression/atlas-Liver.png /expression/atlas-Lung.png /expression/atlas-Pancreas.png /expression/atlas-Pancreatic_Islets.png /expression/atlas-Trachea.png /expression/atlas-Pituitary.png /expression/atlas-Thyroid.png /expression/atlas-Amygdala.png /expression/atlas-Caudate_Nucleus.png /expression/atlas-Cerebellum.png /expression/atlas-Hypothalamus.png /expression/atlas-Spinal_cord.png /expression/atlas-Thalamus.png /expression/atlas-Skin.png /expression/atlas-Ovary.png /expression/atlas-Placenta.png /expression/atlas-Prostate.png /expression/atlas-Testis.png /expression/atlas-Uterus.png
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
expander Expression Legend
  HaemAtlas Expression   Top   Help
Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.
CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56
Expression Pattern Moderate Moderate Not Detected Moderate Moderate Moderate Moderate High HaemAtlasProfile
expander Expression Legend
  Interactions from T1DBase   Top   Help
expander Interactions Table for AP4B1:
  Cross-Reference to Pathways and GO Terms   Top   Help
expander View all
expander KEGG Network: 1
Biocarta: None available
expander Reactome: 4
NCI-Nature Pathway Interaction Database: None available
expander Gene Ontology: 11
  Publications   Top   Help
expander Publications: 22
  Model Organism Phenotype Links   Top   Help
This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
Organism Phenotype Resources
Mouse MGI:1337130 IKMC
  External Links   Top   Help
  Human Mouse Rat
Entrez Gene 10717 67489 310746
EnsEMBL Gene(s) ENSG00000134262 ENSMUSG00000032952 ENSRNOG00000019455
Unigene Hs.515048 Mm.197568 Rn.8746
Homologene AP4B1 Ap4b1 Ap4b1
OMIM 607245 N/A N/A
GeneCards AP4B1 N/A N/A
Beta Cell Genomics DT.100682194 DT.100685471 DT.215048 DT.95099109 DT.95300298 DT.101255340 DT.101272109 DT.101342709 DT.101735507 DT.40180772 DT.99857395 N/A
Reactome Q9Y6B7 N/A N/A
Plasma Peptide Atlas N/A N/A N/A
MGI N/A MGI:1337130 N/A
WikiGenes 10717 67489 310746
  External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network   Top   Help
dkCOIN_click Relevant resources:
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