HCG9
| Gene Description: |
HLA complex group 9 (non-protein coding) |
| Synonyms: |
HCGIX, HCG9, HCGIX4 |
| Orthologs: |
Human HCG9 (miscRNA)
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Sources
Sources
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Possible sources:
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HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG
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Regions of Interest Overlapping this feature from T1DBase
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Regions Overlapping this Feature:
Human: 1
Associated Regions: Available
Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.
Gene Overview from T1DBase
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Beta Cell Gene Atlas from T1DBase
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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The Beta Cell Gene Atlas is a collection of almost all available public microarray
data generated with pancreatic beta cells and related cell lines and types. The
expression data comes from 131 array analyses derived from 28 experiments
(open details in a new window).
The basal (untreated cell) expression signal intensity values in each array
were converted to ranks within the experiments; the highest value was used for
genes represented by more than one probe. The rank values of genes in a given cell
type were averaged with other calculated values from experiments performed with the
same cell type. The rank transformation of the expression values enable comparison
of gene expression across different organisms and tissues.
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A red border around a cell indicates greater certainty in the data;
specifically, the gene has >0.95 probability of being expressed in the tissue.
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| Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.
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Expression Legend
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Signal intensity values were converted to ranks within the experiments.
For genes represented by more than one probeset, we averaged the intensity
signals for each probeset across all tissues and chose the probeset with the
highest average value. The rank transformation of the expression values enables
comparison of gene expression across different organisms and tissues.
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Cross-Reference to Pathways and GO Terms
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KEGG Network: None available
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Biocarta: None available
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Reactome: None available
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NCI-Nature Pathway Interaction Database: None available
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Gene Ontology: None available
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KEGG Network: None available
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NCI-Nature Pathway Interaction Database: None available
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Gene Ontology: None available
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Publications: 9
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Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
Jin Y, Birlea SA, Fain PR, Gowan K, Riccardi SL, Holland PJ, Mailloux CM, Sufit AJ, Hutton SM, Amadi-Myers A, Bennett DC, Wallace MR, McCormack WT, Kemp EH, Gawkrodger DJ, Weetman AP, Picardo M, Leone G, Taïeb A, Jouary T, Ezzedine K, van Geel N, Lambert J, Overbeck A, Spritz RA
N Engl J Med. 2010
PubMed ID: 20410501
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A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.
Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL, IMAGEN, IMSGC
PLoS One. 2010
PubMed ID: 20593013
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High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
PLoS Genet. 2009
PubMed ID: 19851445
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Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, Gojobori T, Inoko H, Bahram S
Genetics. 2006
PubMed ID: 16702430
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Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
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Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region.
Shiina T, Tamiya G, Oka A, Takishima N, Yamagata T, Kikkawa E, Iwata K, Tomizawa M, Okuaki N, Kuwano Y, Watanabe K, Fukuzumi Y, Itakura S, Sugawara C, Ono A, Yamazaki M, Tashiro H, Ando A, Ikemura T, Soeda E, Kimura M, Bahram S, Inoko H
Proc Natl Acad Sci U S A. 1999
PubMed ID: 10557312
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A 356-Kb sequence of the subtelomeric part of the MHC Class I region.
Hampe A, Coriton O, Andrieux N, Carn G, Lepourcelet M, Mottier S, Dréano S, Gatius MT, Hitte C, Soriano N, Galibert F
DNA Seq. 1999
PubMed ID: 10727083
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A new non-HLA multigene family associated with the PERB11 family within the MHC class I region.
Pichon L, Hampe A, Giffon T, Carn G, Legall JY, David V
Immunogenetics. 1996
PubMed ID: 8753856
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Physical map of the HLA-A/HLA-F subregion and identification of two new coding sequences.
Pichon L, Giffon T, Chauvel B, Carn G, Bouric P, El Kahloun A, Legall JY, David V
Immunogenetics. 1996
PubMed ID: 8575815
Model Organism Phenotype Links
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This section provides links to model organism phenotype resources. Currently only to mouse phenotypes.
No mouse phenotype links available for this gene.
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Human
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Mouse
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Rat
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Entrez Gene
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10255
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N/A
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N/A
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EnsEMBL Gene(s)
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N/A
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N/A
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N/A
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Unigene
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Hs.656251
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N/A
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N/A
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Homologene
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HCG9
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N/A
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N/A
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OMIM
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N/A
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N/A
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N/A
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GeneCards
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HCG9
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N/A
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N/A
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Beta Cell Genomics
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DT.307579
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N/A
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N/A
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Reactome
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N/A
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N/A
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N/A
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Plasma Peptide Atlas
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N/A
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N/A
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N/A
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MGI
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N/A
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N/A
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N/A
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WikiGenes
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10255
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N/A
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N/A
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External resources (dkCOIN) from NIDDK Consortium Interconnectivity Network
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Relevant resources:
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