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FLOT1

Gene Description:   flotillin 1 Synonyms:   reggie-2, Rareg, FLOT1, Flot1 Orthologs:   Human FLOT1 (protein-coding), Mouse Flot1 (protein-coding), Rat Flot1 (protein-coding)   Sources Sources Human-Mouse: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Human-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Mouse-Rat: HomoloGene, MGD, RGD, Inparanoid, OrthoMCL Possible sources: HomoloGene, MGD, RGD, Ensembl, Inparanoid, OrthoMCL, KEGG

Regions Overlapping this Feature:  Human: 1 Mouse: 1

Associated Regions: Available

Regions were calculated based on variants available for a large study with a convincing p-value (P < 5 x 10^-8) +/- 0.1cM, and then these regions were examined for genes based on the current set of T1DBase gene spans.

Region	Species	Chromosomal Location	Mb	Number of genes	Marker
MHC	Human	chr6:29910021..33498585	3.59	688

Linkage Regions: Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd24	Mouse	chr17:35340111..41438922	6.10	184

(Human) GRCh37 - chr6:30695486..30710510 (152 kb)  View in Genome Browser

(Mouse) NCBIM37 - chr17:35960175..35969736 (9.56 kb)  View in Genome Browser

(Rat) RGSC3.4 - chr20:3065783..3076166 (10.38 kb)  View in Genome Browser

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human Mouse Rat ductal cells exocrine pancreas pancreatic islets primary beta cells Pancreatic Islets MPSS beta cell line pancreatic islets whole pancreas alpha cell beta cell line pancreatic islets primary beta cells whole pancreas

Expression Legend   Range 0                                                                                                     100                                                                                                       No Data The Beta Cell Gene Atlas is a collection of almost all available public microarray data generated with pancreatic beta cells and related cell lines and types. The expression data comes from 131 array analyses derived from 28 experiments (open details in a new window). The basal (untreated cell) expression signal intensity values in each array were converted to ranks within the experiments; the highest value was used for genes represented by more than one probe. The rank values of genes in a given cell type were averaged with other calculated values from experiments performed with the same cell type. The rank transformation of the expression values enable comparison of gene expression across different organisms and tissues. A red border around a cell indicates greater certainty in the data; specifically, the gene has >0.95 probability of being expressed in the tissue.

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Range 0                                                                                                     100                                                                                                       No Data

Signal intensity values were converted to ranks within the experiments. For genes represented by more than one probeset, we averaged the intensity signals for each probeset across all tissues and chose the probeset with the highest average value. The rank transformation of the expression values enables comparison of gene expression across different organisms and tissues.

Symbols represent expression compared with the overall mean. Please click 'HaemAtlasProfile' link below for associated probe mappings and a detailed profile.

CD Marker EB MK CD66b CD14 CD19 CD8 CD4 CD56 Expression Pattern HaemAtlasProfile

Expression Legend CD Marker Cell Type Lineage EB Erythroblast PRECURSOR MK Megakaryocyte PRECURSOR CD66b Granulocyte MYELOID CD14 Monocyte MYELOID CD19 B Lymphocyte LYMPHOID CD8 Tc Lymphocyte LYMPHOID CD4 Th Lymphocyte LYMPHOID CD56 Natural Killer cell LYMPHOID Symbol Expression Level High Moderate Low Not Detected

Interactions Table for FLOT1: The FLOT1 interactions are shown below. Each row lists the two interactors, the sources which document this as an interaction, a classification of the interaction as empirical or predicted, and Pubmed IDs (if any) for the interaction. The table of interactions is downloadable as a text file. Please note that the text file will not include data from HPRD due to restrictions imposed by the HPRD funding sources. Interactor Interactor Sources Classification Pubmed IDs FLOT1   SORBS3   BioGRID  empirical  11481476  FLOT1   SORBS1   HPRD, BioGRID  empirical  11481476  15128873  11001060  FLOT1   CBX1   IntAct  empirical  20360068  FLOT1   COPS5   IntAct  empirical  18850735  FLOT1   TRIM69   IntAct  empirical  20360068  FLOT1   FLOT2   HPRD, MINT  empirical  17113085  19298817  FLOT1   FYN   HPRD  empirical  11598189  FLOT1   SESN1   Sanger Interaction Map  predicted  15345047  FLOT1   GRIN1   MINT  empirical  19298817  FLOT1   GRIN2A   MINT  empirical  19298817  FLOT1   GRIN2B   MINT  empirical  19298817  FLOT1   APP   HPRD, IntAct  empirical  16480949  FLOT1   ARG1   HPRD, MINT  empirical  17113085  FLOT1   LAMP2   MINT  empirical  16917501  FLOT1   GOLM1   HPRD, MINT, IntAct  empirical  16169070  FLOT1   ATP6V1A   IntAct  empirical  21674799  FLOT1   BBS7   IntAct  empirical  18000879  FLOT1   NGB   HPRD  empirical  15120622  FLOT1   BBS1   IntAct  empirical  18000879  FLOT1   BBS2   IntAct  empirical  18000879  FLOT1   BBS4   IntAct  empirical  18000879  FLOT1   SHBG   HPRD  empirical  15862967  FLOT1   SLC2A4   IntAct  empirical  16396496  FLOT1   UBC   BioGRID  empirical  16196087  FLOT1   YWHAB   IntAct  empirical  16635246  FLOT1   SORBS2   HPRD, BioGRID  empirical  15128873  FLOT1   CAV1   IntAct, BioGRID  empirical  10212252  FLOT1   CBL   BioGRID  empirical  11001060

View all

KEGG Network: 1   Insulin signaling pathway Human - 4910 Mouse - 4910 Rat - 4910

Biocarta: None available   None available.

Reactome: None available   None available.

NCI-Nature Pathway Interaction Database: None available   None available.

Gene Ontology: 12   Protein binding GO:0005515 Membrane fraction GO:0005624 Endosome GO:0005768 Microtubule organizing center GO:0005815 Plasma membrane GO:0005886 Caveola GO:0005901 Signalosome GO:0008180 Integral to membrane GO:0016021 Flotillin complex GO:0016600 Centriolar satellite GO:0034451 Melanosome GO:0042470 Membrane raft GO:0045121

	KEGG Network: 1 Insulin signaling pathway Human - 4910 Mouse - 4910 Rat - 4910
	Biocarta: None available
	Reactome: None available
	NCI-Nature Pathway Interaction Database: None available
	Gene Ontology: 12 Protein binding GO:0005515 Membrane fraction GO:0005624 Endosome GO:0005768 Microtubule organizing center GO:0005815 Plasma membrane GO:0005886 Caveola GO:0005901 Signalosome GO:0008180 Integral to membrane GO:0016021 Flotillin complex GO:0016600 Centriolar satellite GO:0034451 Melanosome GO:0042470 Membrane raft GO:0045121

Publications: 85

• Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.
  Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A
  Nat Neurosci. 2011
  PubMed ID: 21399631
   
  
• Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.
  Ge L, Qi W, Wang LJ, Miao HH, Qu YX, Li BL, Song BL
  Proc Natl Acad Sci U S A. 2011
  PubMed ID: 21187433
   
  
• A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
  Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
  PLoS Biol. 2011
  PubMed ID: 21267068
   
  
• Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment.
  Ludwig A, Otto GP, Riento K, Hams E, Fallon PG, Nichols BJ
  J Cell Biol. 2010
  PubMed ID: 21059848
   
  
• Flotillin-mediated endocytic events dictate cell type-specific responses to semaphorin 3A.
  Carcea I, Ma'ayan A, Mesias R, Sepulveda B, Salton SR, Benson DL
  J Neurosci. 2010
  PubMed ID: 21068336
   
  
• Flotillin-1 promotes formation of glutamatergic synapses in hippocampal neurons.
  Swanwick CC, Shapiro ME, Vicini S, Wenthold RJ
  Dev Neurobiol. 2010
  PubMed ID: 20669324
   
  
• Flotillin-1 mediates neurite branching induced by synaptic adhesion-like molecule 4 in hippocampal neurons.
  Swanwick CC, Shapiro ME, Vicini S, Wenthold RJ
  Mol Cell Neurosci. 2010
  PubMed ID: 20600927
   
  
• A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.
  Gorbea C, Pratt G, Ustrell V, Bell R, Sahasrabudhe S, Hughes RE, Rechsteiner M
  J Biol Chem. 2010
  PubMed ID: 20682791
   
  
• LGI3 interacts with flotillin-1 to mediate APP trafficking and exosome formation.
  Okabayashi S, Kimura N
  Neuroreport. 2010
  PubMed ID: 20461023
   
  
• The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
  Hryciw T, MacDonald JI, Phillips R, Seah C, Pasternak S, Meakin SO
  J Neurochem. 2010
  PubMed ID: 19943849
   
  
• The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.
  Lee BY, Jethwaney D, Schilling B, Clemens DL, Gibson BW, Horwitz MA
  Mol Cell Proteomics. 2010
  PubMed ID: 19815536
   
  
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
  PLoS Genet. 2009
  PubMed ID: 19851445
   
  
• Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis.
  Babuke T, Ruonala M, Meister M, Amaddii M, Genzler C, Esposito A, Tikkanen R
  Cell Signal. 2009
  PubMed ID: 19318123
   
  
• Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
  Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
  Anal Chem. 2009
  PubMed ID: 19413330
   
  
• Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons.
  Munderloh C, Solis GP, Bodrikov V, Jaeger FA, Wiechers M, Málaga-Trillo E, Stuermer CA
  J Neurosci. 2009
  PubMed ID: 19458231
   
  
• Protein delivery with transportans is mediated by caveolae rather than flotillin-dependent pathways.
  Säälik P, Padari K, Niinep A, Lorents A, Hansen M, Jokitalo E, Langel U, Pooga M
  Bioconjug Chem. 2009
  PubMed ID: 19348413
   
  
• Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm.
  Miranda PV, Allaire A, Sosnik J, Visconti PE
  Biol Reprod. 2009
  PubMed ID: 19144954
   
  
• NMDA receptors interact with flotillin-1 and -2, lipid raft-associated proteins.
  Swanwick CC, Shapiro ME, Yi Z, Chang K, Wenthold RJ
  FEBS Lett. 2009
  PubMed ID: 19298817
   
  
• Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase.
  Riento K, Frick M, Schafer I, Nichols BJ
  J Cell Sci. 2009
  PubMed ID: 19258392
   
  
• Flotillin-1 stabilizes caveolin-1 in intestinal epithelial cells.
  Vassilieva EV, Ivanov AI, Nusrat A
  Biochem Biophys Res Commun. 2009
  PubMed ID: 19121286
   
  
• Flotillins are involved in the polarization of primitive and mature hematopoietic cells.
  Rajendran L, Beckmann J, Magenau A, Boneberg EM, Gaus K, Viola A, Giebel B, Illges H
  PLoS One. 2009
  PubMed ID: 20027317
   
  
• Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
  Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
  Sci Signal. 2009
  PubMed ID: 19690332
   
  
• Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod.
  Rossy J, Schlicht D, Engelhardt B, Niggli V
  PLoS One. 2009
  PubMed ID: 19404397
   
  
• Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
  Wang B, Malik R, Nigg EA, Körner R
  Anal Chem. 2008
  PubMed ID: 19007248
   
  
• Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.
  Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ, Huang L
  J Proteome Res. 2008
  PubMed ID: 18850735
   
  
• Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
  Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Körner R, Greff Z, Kéri G, Stemmann O, Mann M
  Mol Cell. 2008
  PubMed ID: 18691976
   
  
• Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
  Lu Y, Dollé ME, Imholz S, Slot RV, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM
  J Lipid Res. 2008
  PubMed ID: 18660489
   
  
• Toward a confocal subcellular atlas of the human proteome.
  Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
  Mol Cell Proteomics. 2008
  PubMed ID: 18029348
   
  
• Novel interaction partners of Bardet-Biedl syndrome proteins.
  Oeffner F, Moch C, Neundorf A, Hofmann J, Koch M, Grzeschik KH
  Cell Motil Cytoskeleton. 2008
  PubMed ID: 18000879
   
  
• Immunohistochemical study of flotillin-1 in the rat testis during postnatal development.
  Kim H, Moon C, Shin T
  Acta Histochem. 2008
  PubMed ID: 18155272
   
  
• Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
  Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ
  Cell. 2007
  PubMed ID: 18083107
   
  
• Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection.
  Hagedorn M, Soldati T
  Cell Microbiol. 2007
  PubMed ID: 17587329
   
  
• Nerve growth factor stimulates the concentration of TrkA within lipid rafts and extracellular signal-regulated kinase activation through c-Cbl-associated protein.
  Limpert AS, Karlo JC, Landreth GE
  Mol Cell Biol. 2007
  PubMed ID: 17548467
   
  
• Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding.
  Frick M, Bright NA, Riento K, Bray A, Merrified C, Nichols BJ
  Curr Biol. 2007
  PubMed ID: 17600709
   
  
• The lipid raft proteins flotillins/reggies interact with Galphaq and are involved in Gq-mediated p38 mitogen-activated protein kinase activation through tyrosine kinase.
  Sugawara Y, Nishii H, Takahashi T, Yamauchi J, Mizuno N, Tago K, Itoh H
  Cell Signal. 2007
  PubMed ID: 17307333
   
  
• Immunohistochemical study of flotillin-1 in rat testis with ischemia/reperfusion injury.
  Jeong CW, Kim H, Kim S, Kim SH, Moon C, Shin T
  Cell Biol Int. 2007
  PubMed ID: 17218121
   
  
• Reggie/flotillin proteins are organized into stable tetramers in membrane microdomains.
  Solis GP, Hoegg M, Munderloh C, Schrock Y, Malaga-Trillo E, Rivera-Milla E, Stuermer CA
  Biochem J. 2007
  PubMed ID: 17206938
   
  
• Arginase-flotillin interaction brings arginase to red blood cell membrane.
  Jiang M, Ding Y, Su Y, Hu X, Li J, Zhang Z
  FEBS Lett. 2006
  PubMed ID: 17113085
   
  
• Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
  Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF
  J Proteome Res. 2006
  PubMed ID: 17081065
   
  
• Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells.
  Kato N, Nakanishi M, Hirashima N
  J Immunol. 2006
  PubMed ID: 16785509
   
  
• Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.
  Fecchi K, Volonte D, Hezel MP, Schmeck K, Galbiati F
  FASEB J. 2006
  PubMed ID: 16455755
   
  
• The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein.
  Chen TY, Liu PH, Ruan CT, Chiu L, Kung FL
  Biochem Biophys Res Commun. 2006
  PubMed ID: 16480949
   
  
• Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells.
  Glebov OO, Bright NA, Nichols BJ
  Nat Cell Biol. 2006
  PubMed ID: 16341206
   
  
• Identification of flotillin-1 as a protein interacting with myocilin: implications for the pathogenesis of primary open-angle glaucoma.
  Joe MK, Sohn S, Choi YR, Park H, Kee C
  Biochem Biophys Res Commun. 2005
  PubMed ID: 16198165
   
  
• A human protein-protein interaction network: a resource for annotating the proteome.
  Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
  Cell. 2005
  PubMed ID: 16169070
   
  
• Antisense transcription in the mammalian transcriptome.
  Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
  Science. 2005
  PubMed ID: 16141073
   
  
• The transcriptional landscape of the mammalian genome.
  Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
  Science. 2005
  PubMed ID: 16141072
   
  
• Expression, purification, and characterization of recombinant human flotillin-1 in Escherichia coli.
  Ding Y, Jiang M, Jiang W, Su Y, Zhou H, Hu X, Zhang Z
  Protein Expr Purif. 2005
  PubMed ID: 15939299
   
  
• Protein tyrosine nitration in rat brain is associated with raft proteins, flotillin-1 and alpha-tubulin: effect of biological aging.
  Dremina ES, Sharov VS, Schöneich C
  J Neurochem. 2005
  PubMed ID: 15934946
   
  
• Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin.
  Pope SN, Lee IR
  J Steroid Biochem Mol Biol. 2005
  PubMed ID: 15862967
   
  
• Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
  Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
  Nat Methods. 2004
  PubMed ID: 15782199
   
  
• D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells.
  Yu P, Yang Z, Jones JE, Wang Z, Owens SA, Mueller SC, Felder RA, Jose PA
  Kidney Int. 2004
  PubMed ID: 15569306
   
  
• Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
  Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G
  Mol Biol Cell. 2004
  PubMed ID: 15469992
   
  
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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