TRIM28

Summary Top Help

Gene Description:

tripartite motif-containing 28; tripartite motif containing 28

Synonyms:

Tif1beta, TIF1B, RNF96, TF1B, KAP-1, AA408787, Trim28, KRIP-1, Kap1, Krip1, Tif1b, KAP1, TRIM28

Orthologs:

Human TRIM28 (protein-coding), Mouse Trim28 (protein-coding), Rat Trim28 (protein-coding)

Sources

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr19:59055836..59062082 (6.25 kb) View in Genome Browser

(Mouse) NCBIM37 - chr7:13609501..13616384 (6.88 kb) View in Genome Browser

(Rat) RGSC3.4 - chr1:72892399..72899070 (6.67 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for TRIM28:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for TRIM28:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: None available

Biocarta: None available

Reactome: None available

NCI-Nature Pathway Interaction Database: 4

Gene Ontology: 30

Publications from PubMed Top Help

Publications: 190

Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
Yang W, Thompson JW, Wang Z, Wang L, Sheng H, Foster MW, Moseley MA, Paschen W
J Proteome Res. 2012
PubMed ID: 22082260
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs).
Lopitz-Otsoa F, Rodriguez-Suarez E, Aillet F, Casado-Vela J, Lang V, Matthiesen R, Elortza F, Rodriguez MS
J Proteomics. 2011
PubMed ID: 22178446
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR
J Biol Chem. 2011
PubMed ID: 21987572
TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.
Shibata M, Blauvelt KE, Liem KF, García-García MJ
Development. 2011
PubMed ID: 22110054
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.
Altun M, Kramer HB, Willems LI, McDermott JL, Leach CA, Goldenberg SJ, Kumar KG, Konietzny R, Fischer R, Kogan E, Mackeen MM, McGouran J, Khoronenkova SV, Parsons JL, Dianov GL, Nicholson B, Kessler BM
Chem Biol. 2011
PubMed ID: 22118674
In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions.
Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D
Mol Cell. 2011
PubMed ID: 22055183
Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.
Liang Q, Deng H, Li X, Wu X, Tang Q, Chang TH, Peng H, Rauscher FJ, Ozato K, Zhu F
J Immunol. 2011
PubMed ID: 21940674
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.
Jeevan-Raj BP, Robert I, Heyer V, Page A, Wang JH, Cammas F, Alt FW, Losson R, Reina-San-Martin B
J Exp Med. 2011
PubMed ID: 21746811
KAP1 protein: an enigmatic master regulator of the genome.
Iyengar S, Farnham PJ
J Biol Chem. 2011
PubMed ID: 21652716
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.
Goodarzi AA, Kurka T, Jeggo PA
Nat Struct Mol Biol. 2011
PubMed ID: 21642969
The TRIM family protein KAP1 inhibits HIV-1 integration.
Allouch A, Di Primio C, Alpi E, Lusic M, Arosio D, Giacca M, Cereseto A
Cell Host Microbe. 2011
PubMed ID: 21669397
The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response.
Maruyama A, Nishikawa K, Kawatani Y, Mimura J, Hosoya T, Harada N, Yamamato M, Itoh K
Biochem J. 2011
PubMed ID: 21382013
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma.
Herquel B, Ouararhni K, Khetchoumian K, Ignat M, Teletin M, Mark M, Béchade G, Van Dorsselaer A, Sanglier-Cianférani S, Hamiche A, Cammas F, Davidson I, Losson R
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21531907
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation.
Okazaki IM, Okawa K, Kobayashi M, Yoshikawa K, Kawamoto S, Nagaoka H, Shinkura R, Kitawaki Y, Taniguchi H, Natsume T, Iemura S, Honjo T
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21518874
Functional analysis of KAP1 genomic recruitment.
Iyengar S, Ivanov AV, Jin VX, Rauscher FJ, Farnham PJ
Mol Cell Biol. 2011
PubMed ID: 21343339
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Jo Y, Sguigna PV, DeBose-Boyd RA
J Biol Chem. 2011
PubMed ID: 21343306
A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1.
Narayan V, Halada P, Hernychová L, Chong YP, Žáková J, Hupp TR, Vojtesek B, Ball KL
J Biol Chem. 2011
PubMed ID: 21245151
TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.
Herzog M, Wendling O, Guillou F, Chambon P, Mark M, Losson R, Cammas F
Dev Biol. 2011
PubMed ID: 21163256
Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.
Campbell GR, Baudhuin A, Vranizan K, Ngai J
Mol Cell Neurosci. 2011
PubMed ID: 21194568
Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.
Greco TM, Yu F, Guise AJ, Cristea IM
Mol Cell Proteomics. 2011
PubMed ID: 21081666
KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin.
Kepkay R, Attwood KM, Ziv Y, Shiloh Y, Dellaire G
Cell Cycle. 2011
PubMed ID: 21228624
MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression.
Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ
PLoS One. 2011
PubMed ID: 21876767
A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.
Meylan S, Groner AC, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman FD, Bucher P, Trono D
BMC Genomics. 2011
PubMed ID: 21791101
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J
BMC Syst Biol. 2011
PubMed ID: 21269460
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ
Nature. 2010
PubMed ID: 21150899
Identification of differential protein interactors of lamin A and progerin.
Kubben N, Voncken JW, Demmers J, Calis C, van Almen G, Pinto Y, Misteli T
Nucleus. 2010
PubMed ID: 21327095
Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1).
Higo S, Asano Y, Kato H, Yamazaki S, Nakano A, Tsukamoto O, Seguchi O, Asai M, Asakura M, Asanuma H, Sanada S, Minamino T, Komuro I, Kitakaze M, Takashima S
J Biol Chem. 2010
PubMed ID: 20675861
A human MAP kinase interactome.
Bandyopadhyay S, Chiang CY, Srivastava J, Gersten M, White S, Bell R, Kurschner C, Martin CH, Smoot M, Sahasrabudhe S, Barber DL, Chanda SK, Ideker T
Nat Methods. 2010
PubMed ID: 20936779
Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.
Gilmore-Hebert M, Ramabhadran R, Stern DF
Mol Cancer Res. 2010
PubMed ID: 20858735
MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.
Doyle JM, Gao J, Wang J, Yang M, Potts PR
Mol Cell. 2010
PubMed ID: 20864041
SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.
Mallette FA, Calabrese V, Ilangumaran S, Ferbeyre G
Aging (Albany NY). 2010
PubMed ID: 20622265
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.
Nozawa RS, Nagao K, Masuda HT, Iwasaki O, Hirota T, Nozaki N, Kimura H, Obuse C
Nat Cell Biol. 2010
PubMed ID: 20562864
ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC, Tora L
EMBO Rep. 2010
PubMed ID: 20508642
In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification.
Blomster HA, Imanishi SY, Siimes J, Kastu J, Morrice NA, Eriksson JE, Sistonen L
J Biol Chem. 2010
PubMed ID: 20388717
TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.
Seki Y, Kurisaki A, Watanabe-Susaki K, Nakajima Y, Nakanishi M, Arai Y, Shiota K, Sugino H, Asashima M
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20508149
The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation.
Losson R, Nielsen AL
Biochim Biophys Acta. 2010
PubMed ID: 20176155
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM
Science. 2010
PubMed ID: 20360068
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Dev Cell. 2010
PubMed ID: 20412781
An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, Han JH, Hashimoto T, Hide W, Hofmann O, Kamburov A, Kaur M, Kawaji H, Kubosaki A, Lassmann T, van Nimwegen E, MacPherson CR, Ogawa C, Radovanovic A, Schwartz A, Teasdale RD, Tegnér J, Lenhard B, Teichmann SA, Arakawa T, Ninomiya N, Murakami K, Tagami M, Fukuda S, Imamura K, Kai C, Ishihara R, Kitazume Y, Kawai J, Hume DA, Ideker T, Hayashizaki Y
Cell. 2010
PubMed ID: 20211142
Histone deacetylase 10 relieves repression on the melanogenic program by maintaining the deacetylation status of repressors.
Lai IL, Lin TP, Yao YL, Lin CY, Hsieh MJ, Yang WM
J Biol Chem. 2010
PubMed ID: 20032463
KAP1 is associated with peritoneal carcinomatosis in gastric cancer.
Yokoe T, Toiyama Y, Okugawa Y, Tanaka K, Ohi M, Inoue Y, Mohri Y, Miki C, Kusunoki M
Ann Surg Oncol. 2010
PubMed ID: 19898899
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
Noon AT, Shibata A, Rief N, Löbrich M, Stewart GS, Jeggo PA, Goodarzi AA
Nat Cell Biol. 2010
PubMed ID: 20081839
KAP1 controls endogenous retroviruses in embryonic stem cells.
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D
Nature. 2010
PubMed ID: 20075919
Aire's partners in the molecular control of immunological tolerance.
Abramson J, Giraud M, Benoist C, Mathis D
Cell. 2010
PubMed ID: 20085707
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes.
Frietze S, O'Geen H, Blahnik KR, Jin VX, Farnham PJ
PLoS One. 2010
PubMed ID: 21170338
Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.
Whitelaw NC, Chong S, Morgan DK, Nestor C, Bruxner TJ, Ashe A, Lambley E, Meehan R, Whitelaw E
Genome Biol. 2010
PubMed ID: 21092094
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.
Li X, Lin HH, Chen H, Xu X, Shih HM, Ann DK
Sci Signal. 2010
PubMed ID: 20424263
KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading.
Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D
PLoS Genet. 2010
PubMed ID: 20221260
Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.
Peng H, Ivanov AV, Oh HJ, Lau YF, Rauscher FJ
J Biol Chem. 2009
PubMed ID: 19850934
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Dev Cell. 2009
PubMed ID: 20059953
The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.
Crawford NP, Yang H, Mattaini KR, Hunter KW
J Biol Chem. 2009
PubMed ID: 19710015
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier.
Cardinale S, Bergmann JH, Kelly D, Nakano M, Valdivia MM, Kimura H, Masumoto H, Larionov V, Earnshaw WC
Mol Biol Cell. 2009
PubMed ID: 19656847
Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.
Matafora V, D'Amato A, Mori S, Blasi F, Bachi A
Mol Cell Proteomics. 2009
PubMed ID: 19596686
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M
Science. 2009
PubMed ID: 19608861
Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase.
Chang PC, Fitzgerald LD, Van Geelen A, Izumiya Y, Ellison TJ, Wang DH, Ann DK, Luciw PA, Kung HJ
Cancer Res. 2009
PubMed ID: 19584288
The impact of heterochromatin on DSB repair.
Goodarzi AA, Noon AT, Jeggo PA
Biochem Soc Trans. 2009
PubMed ID: 19442252
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S
Anal Chem. 2009
PubMed ID: 19413330
Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications.
Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D
J Virol. 2009
PubMed ID: 19279087
TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.
Rambaud J, Desroches J, Balsalobre A, Drouin J
J Biol Chem. 2009
PubMed ID: 19321449
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ
Mol Cell Proteomics. 2009
PubMed ID: 19131326
Embryonic stem cells use ZFP809 to silence retroviral DNAs.
Wolf D, Goff SP
Nature. 2009
PubMed ID: 19270682
Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.
Ouyang J, Shi Y, Valin A, Xuan Y, Gill G
Mol Cell. 2009
PubMed ID: 19394292
KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies.
Briers S, Crawford C, Bickmore WA, Sutherland HG
J Cell Sci. 2009
PubMed ID: 19258395
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F
PLoS One. 2009
PubMed ID: 19865483
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.
van Wijk SJ, de Vries SJ, Kemmeren P, Huang A, Boelens R, Bonvin AM, Timmers HT
Mol Syst Biol. 2009
PubMed ID: 19690564
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK
Sci Signal. 2009
PubMed ID: 19690332
An integrated workflow for charting the human interaction proteome: insights into the PP2A system.
Glatter T, Wepf A, Aebersold R, Gstaiger M
Mol Syst Biol. 2009
PubMed ID: 19156129
The phagosomal proteome in interferon-gamma-activated macrophages.
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P
Immunity. 2009
PubMed ID: 19144319
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis.
Wang B, Malik R, Nigg EA, Körner R
Anal Chem. 2008
PubMed ID: 19007248
KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress.
Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, Bensadoun JC, Cammas F, Losson R, Mansuy IM, Sandi C, Trono D
Neuron. 2008
PubMed ID: 19081377
Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
Carrascal M, Ovelleiro D, Casas V, Gay M, Abian J
J Proteome Res. 2008
PubMed ID: 19367720
Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry.
Zanivan S, Gnad F, Wickström SA, Geiger T, Macek B, Cox J, Fässler R, Mann M
J Proteome Res. 2008
PubMed ID: 19367708
The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha.
Quénet D, Gasser V, Fouillen L, Cammas F, Sanglier-Cianferani S, Losson R, Dantzer F
FASEB J. 2008
PubMed ID: 18676401
The novel protein complex with SMARCAD1/KIAA1122 binds to the vicinity of TSS.
Okazaki N, Ikeda S, Ohara R, Shimada K, Yanagawa T, Nagase T, Ohara O, Koga H
J Mol Biol. 2008
PubMed ID: 18675275
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.
Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P, Ferguson-Smith AC
Dev Cell. 2008
PubMed ID: 18854139
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.
Meierhofer D, Wang X, Huang L, Kaiser P
J Proteome Res. 2008
PubMed ID: 18781797
TRIM28 mediates primer binding site-targeted silencing of Lys1,2 tRNA-utilizing retroviruses in embryonic cells.
Wolf D, Hug K, Goff SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18713861
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18669648
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.
Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Löbrich M, Jeggo PA
Mol Cell. 2008
PubMed ID: 18657500
Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing.
Zeng L, Yap KL, Ivanov AV, Wang X, Mujtaba S, Plotnikova O, Rauscher FJ, Zhou MM
Nat Struct Mol Biol. 2008
PubMed ID: 18488044
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z
Nat Cell Biol. 2008
PubMed ID: 18454139
KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression.
Kamitani S, Ohbayashi N, Ikeda O, Togi S, Muromoto R, Sekine Y, Ohta K, Ishiyama H, Matsuda T
Biochem Biophys Res Commun. 2008
PubMed ID: 18381204
Physical and functional interactions between STAT3 and KAP1.
Tsuruma R, Ohbayashi N, Kamitani S, Ikeda O, Sato N, Muromoto R, Sekine Y, Oritani K, Matsuda T
Oncogene. 2008
PubMed ID: 18037959
Primer binding site-dependent restriction of murine leukemia virus requires HP1 binding by TRIM28.
Wolf D, Cammas F, Losson R, Goff SP
J Virol. 2008
PubMed ID: 18287239
GUDMAP: the genitourinary developmental molecular anatomy project.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project
J Am Soc Nephrol. 2008
PubMed ID: 18287559
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
Cantin GT, Yi W, Lu B, Park SK, Xu T, Lee JD, Yates JR
J Proteome Res. 2008
PubMed ID: 18220336
A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.
Suzuki C, Murakumo Y, Kawase Y, Sato T, Morinaga T, Fukuda N, Enomoto A, Ichihara M, Takahashi M
Biochem Biophys Res Commun. 2008
PubMed ID: 18060868
Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.
Chang CW, Chou HY, Lin YS, Huang KH, Chang CJ, Hsu TC, Lee SC
BMC Mol Biol. 2008
PubMed ID: 18590578
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.
Ivanov AV, Peng H, Yurchenko V, Yap KL, Negorev DG, Schultz DC, Psulkowski E, Fredericks WJ, White DE, Maul GG, Sadofsky MJ, Zhou MM, Rauscher FJ
Mol Cell. 2007
PubMed ID: 18082607
Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.
Li X, Lee YK, Jeng JC, Yen Y, Schultz DC, Shih HM, Ann DK
J Biol Chem. 2007
PubMed ID: 17942393
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD
J Proteome Res. 2007
PubMed ID: 17924679
Regulation of E2F1 function by the nuclear corepressor KAP1.
Wang C, Rauscher FJ, Cress WD, Chen J
J Biol Chem. 2007
PubMed ID: 17704056
TRIM28 mediates primer binding site-targeted silencing of murine leukemia virus in embryonic cells.
Wolf D, Goff SP
Cell. 2007
PubMed ID: 17923087
TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.
Pungaliya P, Kulkarni D, Park HJ, Marshall H, Zheng H, Lackland H, Saleem A, Rubin EH
J Proteome Res. 2007
PubMed ID: 17803295
Dynamic and selective interactions of the transcriptional corepressor TIF1 beta with the heterochromatin protein HP1 isotypes during cell differentiation.
Cammas F, Janoshazi A, Lerouge T, Losson R
Differentiation. 2007
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A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.
Smith JC, Duchesne MA, Tozzi P, Ethier M, Figeys D
J Proteome Res. 2007
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An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.
Holaska JM, Wilson KL
Biochemistry. 2007
PubMed ID: 17620012
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B
Mol Cell. 2007
PubMed ID: 17643375
The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain.
Peng H, Gibson LC, Capili AD, Borden KL, Osborne MJ, Harper SL, Speicher DW, Zhao K, Marmorstein R, Rock TA, Rauscher FJ
J Mol Biol. 2007
PubMed ID: 17512541
A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome.
Falsone SF, Gesslbauer B, Rek A, Kungl AJ
Proteomics. 2007
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Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.
O'Geen H, Squazzo SL, Iyengar S, Blahnik K, Rinn JL, Chang HY, Green R, Farnham PJ
PLoS Genet. 2007
PubMed ID: 17542650
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
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Science. 2007
PubMed ID: 17525332
Isolation and characterization of proteins associated with histone H3 tails in vivo.
Heo K, Kim B, Kim K, Choi J, Kim H, Zhan Y, Ranish JA, An W
J Biol Chem. 2007
PubMed ID: 17403666
Patterns of somatic mutation in human cancer genomes.
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR
Nature. 2007
PubMed ID: 17344846
Transcriptional and subcellular regulation of the TRIP-Br family.
Lai IL, Wang SY, Yao YL, Yang WM
Gene. 2007
PubMed ID: 17141982
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.
Molina H, Horn DM, Tang N, Mathivanan S, Pandey A
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17287340
A proximal activator of transcription in epithelial-mesenchymal transition.
Venkov CD, Link AJ, Jennings JL, Plieth D, Inoue T, Nagai K, Xu C, Dimitrova YN, Rauscher FJ, Neilson EG
J Clin Invest. 2007
PubMed ID: 17273560
Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells.
Lee YK, Thomas SN, Yang AJ, Ann DK
J Biol Chem. 2007
PubMed ID: 17079232
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR, Menssen A, Hermeking H
Cell Cycle. 2007
PubMed ID: 17314511
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D
Mol Syst Biol. 2007
PubMed ID: 17353931
KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions.
White DE, Negorev D, Peng H, Ivanov AV, Maul GG, Rauscher FJ
Cancer Res. 2006
PubMed ID: 17178852
KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction.
Okamoto K, Kitabayashi I, Taya Y
Biochem Biophys Res Commun. 2006
PubMed ID: 17056014
A protein interaction network for pluripotency of embryonic stem cells.
Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH
Nature. 2006
PubMed ID: 17093407
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell. 2006
PubMed ID: 17081983
The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression.
Sripathy SP, Stevens J, Schultz DC
Mol Cell Biol. 2006
PubMed ID: 16954381
Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1.
Hsieh MJ, Yao YL, Lai IL, Yang WM
Biochem Biophys Res Commun. 2006
PubMed ID: 16945326
A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP
Nat Biotechnol. 2006
PubMed ID: 16964243
The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase.
Delfino FJ, Shaffer JM, Smithgall TE
Biochem J. 2006
PubMed ID: 16792528
Identification of 14-3-3epsilon substrates from embryonic murine brain.
Ballif BA, Cao Z, Schwartz D, Carraway KL, Gygi SP
J Proteome Res. 2006
PubMed ID: 16944949
TIPUH1 encodes a novel KRAB zinc-finger protein highly expressed in human hepatocellular carcinomas.
Silva FP, Hamamoto R, Furukawa Y, Nakamura Y
Oncogene. 2006
PubMed ID: 16568080
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.
Ziv Y, Bielopolski D, Galanty Y, Lukas C, Taya Y, Schultz DC, Lukas J, Bekker-Jensen S, Bartek J, Shiloh Y
Nat Cell Biol. 2006
PubMed ID: 16862143
Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote.
Torres-Padilla ME, Zernicka-Goetz M
J Cell Biol. 2006
PubMed ID: 16880268
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
Large-scale analysis of the human ubiquitin-related proteome.
Matsumoto M, Hatakeyama S, Oyamada K, Oda Y, Nishimura T, Nakayama KI
Proteomics. 2005
PubMed ID: 16196087
The Krüppel-like zinc-finger protein ZNF224 represses aldolase A gene transcription by interacting with the KAP-1 co-repressor protein.
Medugno L, Florio F, De Cegli R, Grosso M, Lupo A, Costanzo P, Izzo P
Gene. 2005
PubMed ID: 16150558
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell. 2005
PubMed ID: 16169070
MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.
Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ, Chen J
EMBO J. 2005
PubMed ID: 16107876
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Global phosphoproteome of HT-29 human colon adenocarcinoma cells.
Kim JE, Tannenbaum SR, White FM
J Proteome Res. 2005
PubMed ID: 16083285
The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.
Lechner MS, Schultz DC, Negorev D, Maul GG, Rauscher FJ
Biochem Biophys Res Commun. 2005
PubMed ID: 15882967
Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.
Oh HJ, Li Y, Lau YF
Biol Reprod. 2005
PubMed ID: 15469996
Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature. 2005
PubMed ID: 15635413
The Epstein-Barr virus replication protein BBLF2/3 provides an origin-tethering function through interaction with the zinc finger DNA binding protein ZBRK1 and the KAP-1 corepressor.
Liao G, Huang J, Fixman ED, Hayward SD
J Virol. 2005
PubMed ID: 15596820
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q
Science. 2004
PubMed ID: 15618518
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.
Khetchoumian K, Teletin M, Mark M, Lerouge T, Cerviño M, Oulad-Abdelghani M, Chambon P, Losson R
J Biol Chem. 2004
PubMed ID: 15322135
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation.
Cammas F, Herzog M, Lerouge T, Chambon P, Losson R
Genes Dev. 2004
PubMed ID: 15342492
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proc Natl Acad Sci U S A. 2004
PubMed ID: 15302935
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
Meek SE, Lane WS, Piwnica-Worms H
J Biol Chem. 2004
PubMed ID: 15161933
Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.
Nomura T, Tanikawa J, Akimaru H, Kanei-Ishii C, Ichikawa-Iwata E, Khan MM, Ito H, Ishii S
J Biol Chem. 2004
PubMed ID: 14761981
Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.
Shu H, Chen S, Bi Q, Mumby M, Brekken DL
Mol Cell Proteomics. 2004
PubMed ID: 14729942
Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Sousa-Nunes R, Rana AA, Kettleborough R, Brickman JM, Clements M, Forrest A, Grimmond S, Avner P, Smith JC, Dunwoodie SL, Beddington RS
Genome Res. 2003
PubMed ID: 14613977
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12904583
Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells.
Germain-Desprez D, Bazinet M, Bouvier M, Aubry M
J Biol Chem. 2003
PubMed ID: 12684500
The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity.
Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G
EMBO J. 2003
PubMed ID: 12682018
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
Control of biochemical reactions through supramolecular RING domain self-assembly.
Kentsis A, Gordon RE, Borden KL
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12438698
Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha.
Nielsen AL, Sanchez C, Ichinose H, Cerviño M, Lerouge T, Chambon P, Losson R
EMBO J. 2002
PubMed ID: 12411497
Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction.
Cammas F, Oulad-Abdelghani M, Vonesch JL, Huss-Garcia Y, Chambon P, Losson R
J Cell Sci. 2002
PubMed ID: 12154074
Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression.
Peng H, Feldman I, Rauscher FJ
J Mol Biol. 2002
PubMed ID: 12096914
Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse.
Weber P, Cammas F, Gerard C, Metzger D, Chambon P, Losson R, Mark M
Development. 2002
PubMed ID: 11973266
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.
Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ
Genes Dev. 2002
PubMed ID: 11959841
Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain.
Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou MM
Mol Cell. 2002
PubMed ID: 11931765
A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein.
Satou A, Taira T, Iguchi-Ariga SM, Ariga H
J Biol Chem. 2001
PubMed ID: 11585818
TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.
Hsu SI, Yang CM, Sim KG, Hentschel DM, O'Leary E, Bonventre JV
EMBO J. 2001
PubMed ID: 11331592
The tripartite motif family identifies cell compartments.
Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A
EMBO J. 2001
PubMed ID: 11331580
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins.
Nielsen AL, Oulad-Abdelghani M, Ortiz JA, Remboutsika E, Chambon P, Losson R
Mol Cell. 2001
PubMed ID: 11336697
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.
Schultz DC, Friedman JR, Rauscher FJ
Genes Dev. 2001
PubMed ID: 11230151
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Krüppel-associated box protein.
Gebelein B, Urrutia R
Mol Cell Biol. 2001
PubMed ID: 11154279
Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains.
Capili AD, Schultz DC, RauscherIII FJ, Borden KL
EMBO J. 2001
PubMed ID: 11226167
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.
Underhill C, Qutob MS, Yee SP, Torchia J
J Biol Chem. 2000
PubMed ID: 11013263
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential.
Lechner MS, Begg GE, Speicher DW, Rauscher FJ
Mol Cell Biol. 2000
PubMed ID: 10938122
Correlation of the exon/intron organization to the conserved domains of the mouse transcriptional corepressor TIF1beta.
Cammas F, Garnier J, Chambon P, Losson R
Gene. 2000
PubMed ID: 10940561
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.
Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH, Becker KG, Ko MS
Proc Natl Acad Sci U S A. 2000
PubMed ID: 10922068
Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development.
Cammas F, Mark M, Dollé P, Dierich A, Chambon P, Losson R
Development. 2000
PubMed ID: 10851139
Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain.
Peng H, Begg GE, Harper SL, Friedman JR, Speicher DW, Rauscher FJ
J Biol Chem. 2000
PubMed ID: 10748030
Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions.
Peng H, Begg GE, Schultz DC, Friedman JR, Jensen DE, Speicher DW, Rauscher FJ
J Mol Biol. 2000
PubMed ID: 10653693
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.
Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P, Losson R
EMBO J. 1999
PubMed ID: 10562550
Two novel Krüppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1beta/KRIP-1).
Agata Y, Matsuda E, Shimizu A
J Biol Chem. 1999
PubMed ID: 10347202
KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.
Ryan RF, Schultz DC, Ayyanathan K, Singh PB, Friedman JR, Fredericks WJ, Rauscher FJ
Mol Cell Biol. 1999
PubMed ID: 10330177
The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin.
Remboutsika E, Lutz Y, Gansmuller A, Vonesch JL, Losson R, Chambon P
J Cell Sci. 1999
PubMed ID: 10318760
Expression of the transcriptional repressor protein Kid-1 leads to the disintegration of the nucleolus.
Huang Z, Philippin B, O'Leary E, Bonventre JV, Kriz W, Witzgall R
J Biol Chem. 1999
PubMed ID: 10075651
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain.
Eng FC, Barsalou A, Akutsu N, Mercier I, Zechel C, Mader S, White JH
J Biol Chem. 1998
PubMed ID: 9774463
Coactivator TIF1beta interacts with transcription factor C/EBPbeta and glucocorticoid receptor to induce alpha1-acid glycoprotein gene expression.
Chang CJ, Chen YL, Lee SC
Mol Cell Biol. 1998
PubMed ID: 9742105
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S
Gene. 1997
PubMed ID: 9373149
A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins.
Kim SS, Chen YM, O'Leary E, Witzgall R, Vidal M, Bonventre JV
Proc Natl Acad Sci U S A. 1996
PubMed ID: 8986806
Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1.
Moosmann P, Georgiev O, Le Douarin B, Bourquin JP, Schaffner W
Nucleic Acids Res. 1996
PubMed ID: 9016654
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
Le Douarin B, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, Chambon P
EMBO J. 1996
PubMed ID: 8978696
KAP-1, a novel corepressor for the highly conserved KRAB repression domain.
Friedman JR, Fredericks WJ, Jensen DE, Speicher DW, Huang XP, Neilson EG, Rauscher FJ
Genes Dev. 1996
PubMed ID: 8769649
Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.
Harrison SM, Dunwoodie SL, Arkell RM, Lehrach H, Beddington RS
Development. 1995
PubMed ID: 7671812
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
Maruyama K, Sugano S
Gene. 1994
PubMed ID: 8125298

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	10155	21849	116698
EnsEMBL Gene(s)	ENSG00000130726	ENSMUSG00000005566	ENSRNOG00000027487
Unigene	Hs.467408	Mm.15701	Rn.198494
Homologene	TRIM28	Trim28	Trim28
OMIM	601742	N/A	N/A
GeneCards	TRIM28	N/A	N/A
Beta Cell Genomics	DT.100673731 DT.100673733 DT.320016 DT.91656083 DT.95143377 DT.95164472 DT.99942398	DT.101240114 DT.103584303 DT.97346152 DT.97372999	N/A
Reactome	N/A	N/A	N/A
Plasma Peptide Atlas	ENSP00000253024	N/A	N/A
WikiGenes	10155	21849	116698

External resources from NIDDK Consortium Interconnectivity Network Top Help

Relevant resources:

View this page in archive site

Interactor	Interactor	Sources	Classification	Pubmed IDs
TRIM28	HDAC5	BioGRID	empirical	21081666
TRIM28	CHAF1A	HPRD, IntAct	empirical	10938122 10747027
TRIM28	PARP2	BioGRID	empirical	18676401
TRIM28	TRIM28	HPRD, IntAct, BioGRID	empirical	12684500 11331580 20360068 10748030 12096914 20864041
TRIM28	ZNF197	HPRD	empirical	12682018
TRIM28	TOPORS	BioGRID	empirical	17803295
TRIM28	CDK9	BioGRID	empirical	17643375
TRIM28	CEBPB	HPRD	empirical	9742105
TRIM28	IPO8	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF274	BioGRID	empirical	21170338
TRIM28	ZNF460	IntAct, BioGRID	empirical	20360068
TRIM28	RUVBL2	BioGRID	empirical	17643375
TRIM28	CBX1	HPRD, IntAct, BioGRID	empirical	10562550 11336697 10330177 21888893 10747027 10938122 18590578 15342492 17381543
TRIM28	YWHAQ	BioGRID	empirical	15161933
TRIM28	CHD3	HPRD, MINT, IntAct, BioGRID	empirical	16169070 21642969
TRIM28	ZWINT	IntAct, BioGRID	empirical	20360068
TRIM28	CBX3	HPRD, IntAct, BioGRID	empirical	10562550 10330177 20936779 21888893 11336697 15342492 17381543 20675861
TRIM28	GABARAPL2	IntAct	empirical	20562859
TRIM28	ZNF689	HPRD	empirical	16568080
TRIM28	TRIM6	BioGRID	empirical	11331580
TRIM28	ZFP42	BioGRID	empirical	17093407
TRIM28	CREBBP	BioGRID	empirical	20508149
TRIM28	PARP1	BioGRID	empirical	18676401
TRIM28	ZNF420	IntAct	empirical	21988832
TRIM28	UBE2U	IntAct, BioGRID	empirical	19690564
TRIM28	ZFP1	IntAct, BioGRID	empirical	20360068
TRIM28	DDB1	IntAct, BioGRID	empirical	20360068
TRIM28	NR0B1	BioGRID	empirical	17093407
TRIM28	EMD	BioGRID	empirical	17620012
TRIM28	ESR1	HPRD	empirical	9774463
TRIM28	RRP1B	BioGRID	empirical	19710015
TRIM28	POGZ	IntAct	empirical	20562864
TRIM28	RPGRIP1L	IntAct	empirical	21565611
TRIM28	CBX5	HPRD, IntAct, BioGRID	empirical	10562550 12154074 10330177 8978696 20562864 21888893 12411497 11336697 10938122 15882967 15342492 17381543
TRIM28	FTH1	BioGRID	empirical	20360068
TRIM28	ZNF324	IntAct, BioGRID	empirical	20360068
TRIM28	SIN3A	BioGRID	empirical	14761981
TRIM28	AMFR	BioGRID	empirical	21343306
TRIM28	NR3C1	HPRD, BioGRID	empirical	9742105
TRIM28	SERTAD1	BioGRID	empirical	17141982
TRIM28	HLA-B	IntAct, BioGRID	empirical	17353931
TRIM28	HLA-C	IntAct	empirical	17353931
TRIM28	NR4A1	BioGRID	empirical	19321449
TRIM28	APC	IntAct	empirical	16212417
TRIM28	AIRE	IntAct, BioGRID	empirical	20085707
TRIM28	TRIM23	BioGRID	empirical	11331580
TRIM28	ARF6	IntAct	empirical	17353931
TRIM28	LMNA	BioGRID	empirical	21327095
TRIM28	ARRB2	IntAct	empirical	17620599
TRIM28	MAGEA6	BioGRID	empirical	20864041
TRIM28	MAGEB2	BioGRID	empirical	20864041
TRIM28	MDM2	BioGRID	empirical	16107876
TRIM28	MYB	BioGRID	empirical	14761981
TRIM28	MYC	IntAct, BioGRID	empirical	17353931 17314511
TRIM28	NDN	BioGRID	empirical	20864041
TRIM28	WRAP73	IntAct	empirical	17353931
TRIM28	PAK2	IntAct	empirical	17353931
TRIM28	PAX3	BioGRID	empirical	20032463 16945326
TRIM28	PFDN5	BioGRID	empirical	11585818
TRIM28	POU5F1	BioGRID	empirical	20508149
TRIM28	HAUS4	IntAct, BioGRID	empirical	20360068
TRIM28	PPP1CA	BioGRID	empirical	20424263
TRIM28	PPP1CB	BioGRID	empirical	20424263
TRIM28	PPP1CC	BioGRID	empirical	20424263
TRIM28	CDCA4	BioGRID	empirical	17141982
TRIM28	PPP2R2B	IntAct, BioGRID	empirical	19156129
TRIM28	ZNF331	IntAct, BioGRID	empirical	20360068
TRIM28	PRKAB1	IntAct	empirical	17353931
TRIM28	NDNL2	BioGRID	empirical	20864041
TRIM28	MEPCE	BioGRID	empirical	17643375
TRIM28	SMARCAD1	BioGRID	empirical	20508149 21549307
TRIM28	POGK	IntAct, BioGRID	empirical	20360068
TRIM28	RBAK	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF250	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF350	BioGRID	empirical	17079232
TRIM28	RCN1	IntAct, BioGRID	empirical	20360068
TRIM28	RCN2	IntAct, BioGRID	empirical	20360068
TRIM28	SKI	BioGRID	empirical	14761981
TRIM28	SMARCA4	BioGRID	empirical	20508149
TRIM28	SMARCC1	BioGRID	empirical	20508149
TRIM28	SUMO3	BioGRID	empirical	22082260
TRIM28	SPG7	HPRD, MINT, IntAct, BioGRID	empirical	16169070
TRIM28	STAT1	BioGRID	empirical	18381204
TRIM28	TADA2A	BioGRID	empirical	20508642
TRIM28	ZNF354A	HPRD, BioGRID	empirical	8986806 20211142
TRIM28	TFE3	IntAct, BioGRID	empirical	17353931
TRIM28	C1QBP	IntAct, BioGRID	empirical	20360068
TRIM28	TP53	BioGRID	empirical	20864041
TRIM28	TRAF6	IntAct	empirical	17353931
TRIM28	UBC	BioGRID	empirical	16196087 22178446 22118674 17623298 18781797 21987572 20864041 21963094 21139048 21890473 21906983
TRIM28	VHL	BioGRID	empirical	12682018
TRIM28	VIM	HPRD, MINT, IntAct, BioGRID	empirical	16169070
TRIM28	YWHAE	BioGRID	empirical	16944949
TRIM28	YWHAZ	MINT	empirical	15161933
TRIM28	ZNF2	BioGRID	empirical	20211142
TRIM28	ZNF8	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF10	HPRD, IntAct, BioGRID	empirical	9016654 10748030 20176155 21170338
TRIM28	ZNF45	Reactome	predicted	16606702 8769649 8183939 14519192 10330177
TRIM28	ZNF74	HPRD, BioGRID	empirical	12684500
TRIM28	ZNF124	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF224	BioGRID	empirical	16150558
TRIM28	MIS12	IntAct, BioGRID	empirical	20360068
TRIM28	ZNF552	IntAct, BioGRID	empirical	20360068
TRIM28	NANOG	IntAct, BioGRID	empirical	17093407 18454139
TRIM28	CALU	IntAct, BioGRID	empirical	20360068
TRIM28	MAP1LC3B	IntAct	empirical	20562859
TRIM28	HIST1H3A	BioGRID	empirical	20424263
TRIM28	HDAC10	BioGRID	empirical	20032463
TRIM28	BCAR3	IntAct	empirical	17353931
TRIM28	MAP1LC3A	IntAct	empirical	20562859
TRIM28	ZNF496	BioGRID	empirical	20176155
TRIM28	ZNF382	HPRD	empirical	11154279
TRIM28	ZNF566	IntAct, BioGRID	empirical	20360068
TRIM28	IKBKG	MINT, IntAct	empirical	14743216
TRIM28	SOCS1	BioGRID	empirical	20622265
TRIM28	TNFRSF10D	IntAct, BioGRID	empirical	17353931
TRIM28	TRIM24	HPRD, BioGRID	empirical	12684500
TRIM28	CCNA1	IntAct	empirical	17353931
TRIM28	CIAO1	IntAct	empirical	17353931
TRIM28	MAGED1	BioGRID	empirical	20864041
TRIM28	NCOR1	IntAct, BioGRID	empirical	11013263 14761981
TRIM28	IKBKE	IntAct	empirical	17353931
TRIM28	IQCB1	IntAct	empirical	21565611
TRIM28	KIAA0101	BioGRID	empirical	21628590
TRIM28	SERTAD2	HPRD, BioGRID	empirical	11331592 17141982
TRIM28	SETDB1	HPRD, BioGRID	empirical	11959841