CDH2

Summary Top Help

Gene Description:

cadherin 2; cadherin 2, type 1, N-cadherin (neuronal)

Synonyms:

CDw325, Cdh2, CD325, CDHN, NCAD, CDH2, N-cadherin, Ncad

Orthologs:

Human CDH2 (protein-coding), Mouse Cdh2 (protein-coding), Rat Cdh2 (protein-coding)

Sources

Overlapping regions from T1DBase Curated Regions Top Help

Regions Overlapping this Feature: Mouse: 1 Rat: 1

Linkage Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes	Linkage and Congenic Studies
Idd21.3	Mouse	chr18:1..21671921	21.67	95

Other Regions: 1 Available

Locus	Species	Chromosomal Location	Mb	Number of genes
Iddm35	Rat	chr18:4320091..76880933	72.56	466

Gene Overview from Genome Browser Top Help

(Human) GRCh37 - chr18:25530930..25757445 (226.51 kb) View in Genome Browser

(Mouse) NCBIM37 - chr18:16747386..16967755 (220.37 kb) View in Genome Browser

(Rat) RGSC3.4 - chr18:8048920..8267974 (2195 kb) View in Genome Browser

HaemAtlas Expression from HaemAtlas Top Help

HaemAtlas Expression Table for CDH2:

Beta Cell Expression from Beta Cell Gene Atlas Top Help

Cell Types Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Human					Mouse			Rat
ductal cells	exocrine pancreas	pancreatic islets	primary beta cells	Pancreatic Islets MPSS	beta cell line	pancreatic islets	whole pancreas	alpha cell	beta cell line	pancreatic islets	primary beta cells	whole pancreas

Expression Legend

Tissue Expression from GNF Gene Atlas Top Help

Tissues Showing Expression: Available

Users should be aware that the scale represents a rank within an experiment rather than a normalized expression signal.

Expression Legend

Interactions Top Help

Interactions Table for CDH2:

Cross-Reference to Pathways and GO Terms Top Help

View all

KEGG Network: 2

Biocarta: None available

Reactome: 5

NCI-Nature Pathway Interaction Database: 4

Gene Ontology: 35

Publications from PubMed Top Help

Type 1 Diabetes Publications: 11

Cadherin Engagement Protects Human {beta}-Cells from Apoptosis.
Parnaud G, Gonelle-Gispert C, Morel P, Giovannoni L, Muller YD, Meier R, Borot S, Berney T, Bosco D
Endocrinology. 2011
PubMed ID: 21990317
N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover.
Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H
Genesis. 2010
PubMed ID: 20533404
Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas.
Rukstalis JM, Habener JF
Gene Expr Patterns. 2007
PubMed ID: 17185046
The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl MS, Karoulias N, Wende H, Strehle M, Birchmeier C
Genes Dev. 2006
PubMed ID: 16951258
N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.
Cavallaro U, Niedermeyer J, Fuxa M, Christofori G
Nat Cell Biol. 2001
PubMed ID: 11433297
Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets.
Esni F, Täljedal IB, Perl AK, Cremer H, Christofori G, Semb H
J Cell Biol. 1999
PubMed ID: 9922458
Distribution of N-cadherin and NCAM in neurons and endocrine cells of the human embryonic and fetal gastroenteropancreatic system.
Gaidar YA, Lepekhin EA, Sheichetova GA, Witt M
Acta Histochem. 1998
PubMed ID: 9542583
Cadherins regulate aggregation of pancreatic beta-cells in vivo.
Dahl U, Sjødin A, Semb H
Development. 1996
PubMed ID: 8787762
Mouse R-cadherin: expression during the organogenesis of pancreas and gastrointestinal tract.
Sjödin A, Dahl U, Semb H
Exp Cell Res. 1995
PubMed ID: 7493641
Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.
Hutton JC, Christofori G, Chi WY, Edman U, Guest PC, Hanahan D, Kelly RB
Mol Endocrinol. 1993
PubMed ID: 8247017
Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas.
Møller CJ, Christgau S, Williamson MR, Madsen OD, Niu ZP, Bock E, Baekkeskov S
Mol Endocrinol. 1992
PubMed ID: 1406710

Publications: 485

Prognostic significance of N-Cadherin expression in oral squamous cell carcinoma.
DI Domenico M, Pierantoni GM, Feola A, Esposito F, Laino L, DE Rosa A, Rullo R, Mazzotta M, Martano M, Sanguedolce F, Perillo L, D'Angelo L, Papagerakis S, Tortorella S, Bufo P, Lo Muzio L, Pannone G, Santoro A
Anticancer Res. 2011
PubMed ID: 22199283
The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.
Asami M, Pilz GA, Ninkovic J, Godinho L, Schroeder T, Huttner WB, Götz M
Development. 2011
PubMed ID: 22031545
A deletion in a cis element of Foxe3 causes cataracts and microphthalmia in rct mice.
Wada K, Maeda YY, Watanabe K, Oshio T, Ueda T, Takahashi G, Yokohama M, Saito J, Seki Y, Takahama S, Ishii R, Shitara H, Taya C, Yonekawa H, Kikkawa Y
Mamm Genome. 2011
PubMed ID: 22002806
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV
Dev Biol. 2011
PubMed ID: 21945075
Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.
Li D, Liu Y, Maruyama M, Zhu W, Chen H, Zhang W, Reuter S, Lin SF, Haneline LS, Field LJ, Chen PS, Shou W
Hum Mol Genet. 2011
PubMed ID: 21880664
Spatiotemporal profile of N-cadherin expression in the mossy fiber sprouting and synaptic plasticity following seizures.
Lin H, Huang Y, Wang Y, Jia J
Mol Cell Biochem. 2011
PubMed ID: 21720765
Impaired stria vascularis integrity upon loss of E-cadherin in basal cells.
Trowe MO, Maier H, Petry M, Schweizer M, Schuster-Gossler K, Kispert A
Dev Biol. 2011
PubMed ID: 21925491
N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation.
Groen RW, de Rooij MF, Kocemba KA, Reijmers RM, de Haan-Kramer A, Overdijk MB, Aalders L, Rozemuller H, Martens AC, Bergsagel PL, Kersten MJ, Pals ST, Spaargaren M
Haematologica. 2011
PubMed ID: 21828122
Motor neuron position and topographic order imposed by β- and γ-catenin activities.
Demireva EY, Shapiro LS, Jessell TM, Zampieri N
Cell. 2011
PubMed ID: 22036570
N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells.
Nalla AK, Estes N, Patel J, Rao JS
Exp Cell Res. 2011
PubMed ID: 21855541
Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup.
Esteve P, Sandonìs A, Ibañez C, Shimono A, Guerrero I, Bovolenta P
Development. 2011
PubMed ID: 21896628
Specific expression of ZO-1 and N-cadherin in rosette structures of various tumors: possible recapitulation of neural tube formation in embryogenesis and utility as a potentially novel immunohistochemical marker of rosette formation in pulmonary neuroendo
Satomi K, Morishita Y, Sakashita S, Kondou Y, Furuya S, Minami Y, Noguchi M
Virchows Arch. 2011
PubMed ID: 21785870
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.
Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT
J Cell Biol. 2011
PubMed ID: 21875946
Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.
Maddala R, Skiba NP, Lalane R, Sherman DL, Brophy PJ, Rao PV
Dev Biol. 2011
PubMed ID: 21745462
Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis.
Plageman TF, Zacharias AL, Gage PJ, Lang RA
Dev Biol. 2011
PubMed ID: 21726547
Cell-extracellular matrix versus cell-cell interactions during the development of the cochlear-vestibular ganglion.
Davies D
J Neurosci Res. 2011
PubMed ID: 21557292
The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs.
Collado MS, Thiede BR, Baker W, Askew C, Igbani LM, Corwin JT
J Neurosci. 2011
PubMed ID: 21849546
SH2B1β regulates N-cadherin levels, cell-cell adhesion and nerve growth factor-induced neurite initiation.
Wang TC, Li YH, Chen KW, Chen CJ, Wu CL, Teng NY, Chen L
J Cell Physiol. 2011
PubMed ID: 21520058
Requirement for N-cadherin-catenin complex in heart development.
Piven OO, Kostetskii IE, Macewicz LL, Kolomiets YM, Radice GL, Lukash LL
Exp Biol Med (Maywood). 2011
PubMed ID: 21680756
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature. 2011
PubMed ID: 21677750
Calcium-dependent dynamics of cadherin interactions at cell-cell junctions.
Kim SA, Tai CY, Mok LP, Mosser EA, Schuman EM
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21613566
Epigenetic activation of human kallikrein 13 enhances malignancy of lung adenocarcinoma by promoting N-cadherin expression and laminin degradation.
Chou RH, Lin SC, Wen HC, Wu CW, Chang WS
Biochem Biophys Res Commun. 2011
PubMed ID: 21596022
Cortactin is required for N-cadherin regulation of Kv1.5 channel function.
Cheng L, Yung A, Covarrubias M, Radice GL
J Biol Chem. 2011
PubMed ID: 21507952
Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex.
Jossin Y, Cooper JA
Nat Neurosci. 2011
PubMed ID: 21516100
Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression.
Yu TH, Yuan RH, Chen YL, Yang WC, Hsu HC, Jeng YM
Mod Pathol. 2011
PubMed ID: 21423153
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.
Katayama K, Melendez J, Baumann JM, Leslie JR, Chauhan BK, Nemkul N, Lang RA, Kuan CY, Zheng Y, Yoshida Y
Proc Natl Acad Sci U S A. 2011
PubMed ID: 21502507
SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
Esteve P, Sandonìs A, Cardozo M, Malapeira J, Ibañez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P
Nat Neurosci. 2011
PubMed ID: 21478884
Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling.
Bharadwaj AG, Goodrich NP, McAtee CO, Haferbier K, Oakley GG, Wahl JK, Simpson MA
Exp Cell Res. 2011
PubMed ID: 21315068
Dimeric states of neural- and epithelial-cadherins are distinguished by the rate of disassembly.
Vunnam N, Flint J, Balbo A, Schuck P, Pedigo S
Biochemistry. 2011
PubMed ID: 21375242
Sequential binding of calcium leads to dimerization in neural cadherin.
Vunnam N, Pedigo S
Biochemistry. 2011
PubMed ID: 21366346
Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing.
Chopra A, Tabdanov E, Patel H, Janmey PA, Kresh JY
Am J Physiol Heart Circ Physiol. 2011
PubMed ID: 21257918
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.
Herzog D, Loetscher P, van Hengel J, Knüsel S, Brakebusch C, Taylor V, Suter U, Relvas JB
J Neurosci. 2011
PubMed ID: 21451048
Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch.
Li F, Lan Y, Wang Y, Wang J, Yang G, Meng F, Han H, Meng A, Wang Y, Yang X
Dev Cell. 2011
PubMed ID: 21397841
Sex differences in expression and subcellular localization of heart rhythm determinant proteins.
Thomas NM, Jasmin JF, Lisanti MP, Iacobas DA
Biochem Biophys Res Commun. 2011
PubMed ID: 21296051
N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein: implications for neurodegeneration in Alzheimer disease.
Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A
J Biol Chem. 2011
PubMed ID: 21177868
N-cadherin loss in POMC-expressing cells leads to pituitary disorganization.
Himes AD, Fiddler RM, Raetzman LT
Mol Endocrinol. 2011
PubMed ID: 21273444
Intrinsic transition of embryonic stem-cell differentiation into neural progenitors.
Kamiya D, Banno S, Sasai N, Ohgushi M, Inomata H, Watanabe K, Kawada M, Yakura R, Kiyonari H, Nakao K, Jakt LM, Nishikawa S, Sasai Y
Nature. 2011
PubMed ID: 21326203
Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination.
Lewallen KA, Shen YA, De la Torre AR, Ng BK, Meijer D, Chan JR
J Neurosci. 2011
PubMed ID: 21414924
Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.
Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Müller U
Neuron. 2011
PubMed ID: 21315259
N-cadherin cell-cell adhesion complexes are regulated by fibronectin matrix assembly.
Lefort CT, Wojciechowski K, Hocking DC
J Biol Chem. 2011
PubMed ID: 21084302
GPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregation.
Hsiao CC, Chen HY, Chang GW, Lin HH
FEBS Lett. 2011
PubMed ID: 21156175
N-cadherin and neuroligins cooperate to regulate synapse formation in hippocampal cultures.
Aiga M, Levinson JN, Bamji SX
J Biol Chem. 2011
PubMed ID: 21056983
High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies.
Quillé ML, Carat S, Quéméner-Redon S, Hirchaud E, Baron D, Benech C, Guihot J, Placet M, Mignen O, Férec C, Houlgatte R, Friocourt G
PLoS One. 2011
PubMed ID: 21966449
A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition.
Howard S, Deroo T, Fujita Y, Itasaki N
PLoS One. 2011
PubMed ID: 21909376
Premature osteoblast clustering by enamel matrix proteins induces osteoblast differentiation through up-regulation of connexin 43 and N-cadherin.
Miron RJ, Hedbom E, Ruggiero S, Bosshardt DD, Zhang Y, Mauth C, Gemperli AC, Iizuka T, Buser D, Sculean A
PLoS One. 2011
PubMed ID: 21858092
Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-cadherin.
Whaley-Connell A, Habibi J, Panfili Z, Hayden MR, Bagree S, Nistala R, Hyder S, Krueger B, Demarco V, Pulakat L, Ferrario CM, Parrish A, Sowers JR
Am J Nephrol. 2011
PubMed ID: 21720156
Presenilin/γ-secretase regulates neurexin processing at synapses.
Saura CA, Servián-Morilla E, Scholl FG
PLoS One. 2011
PubMed ID: 21559374
Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation.
Li B, Zheng YW, Sano Y, Taniguchi H
PLoS One. 2011
PubMed ID: 21347296
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS Biol. 2011
PubMed ID: 21267068
Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis.
Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W
Development. 2011
PubMed ID: 21177343
N-cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region.
Nguyen PT, Kudo Y, Yoshida M, Iizuka S, Ogawa I, Takata T
J Oral Pathol Med. 2011
PubMed ID: 21070371
Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage.
Malinverno M, Carta M, Epis R, Marcello E, Verpelli C, Cattabeni F, Sala C, Mulle C, Di Luca M, Gardoni F
J Neurosci. 2010
PubMed ID: 21123580
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance.
Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T, Fazli L, Wada R, Huang J, Vessella RL, An J, Horvath S, Gleave M, Rettig MB, Wainberg ZA, Reiter RE
Nat Med. 2010
PubMed ID: 21057494
Oncologic trogocytosis with Hospicells induces the expression of N-cadherin by breast cancer cells.
Lis R, Capdet J, Mirshahi P, Lacroix-Triki M, Dagonnet F, Klein C, Mirshahi M, Fournié JJ, Rafii A, Poupot M
Int J Oncol. 2010
PubMed ID: 21042713
Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells.
Govindarajan R, Chakraborty S, Johnson KE, Falk MM, Wheelock MJ, Johnson KR, Mehta PP
Mol Biol Cell. 2010
PubMed ID: 20881055
Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo.
DiVito KA, Trabosh VA, Chen YS, Chen Y, Albanese C, Javelaud D, Mauviel A, Simbulan-Rosenthal CM, Rosenthal DS
Pigment Cell Melanoma Res. 2010
PubMed ID: 20738806
Expression of E- and N-cadherin and CD44 in endometrium and hydrosalpinges from infertile women.
Poncelet C, Cornelis F, Tepper M, Sauce E, Magan N, Wolf JP, Ziol M
Fertil Steril. 2010
PubMed ID: 20605145
Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.
Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY
Circ Res. 2010
PubMed ID: 20847309
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth M, Walentin K, Aue A, Schönheit J, Wuebken A, Pode-Shakked N, Vilianovitch L, Erdmann B, Dekel B, Bader M, Barasch J, Rosenbauer F, Luft FC, Schmidt-Ott KM
Development. 2010
PubMed ID: 20978075
Inhibition of N-cadherin retards smooth muscle cell migration and intimal thickening via induction of apoptosis.
Lyon CA, Koutsouki E, Aguilera CM, Blaschuk OW, George SJ
J Vasc Surg. 2010
PubMed ID: 20630685
[N-cadherin as a receptor for adhesion and endocytosis of Aspergillus fumigatus by human umbilical vein endothelial cells].
Xu XY, Shi Y, Zhang PP, Shen YY, Zhang F, Song Y
Zhonghua Jie He He Hu Xi Za Zhi. 2010
PubMed ID: 21176502
TC21 promotes cell motility and metastasis by regulating the expression of E-cadherin and N-cadherin in hepatocellular carcinoma.
Luo H, Hao X, Ge C, Zhao F, Zhu M, Chen T, Yao M, He X, Li J
Int J Oncol. 2010
PubMed ID: 20811707
The cleavage of N-cadherin is essential for chondrocyte differentiation.
Nakazora S, Matsumine A, Iino T, Hasegawa M, Kinoshita A, Uemura K, Niimi R, Uchida A, Sudo A
Biochem Biophys Res Commun. 2010
PubMed ID: 20735983
Developmental changes of cell adhesion molecule expression in the fetal mouse liver.
Sugiyama Y, Koike T, Shiojiri N
Anat Rec (Hoboken). 2010
PubMed ID: 20687112
Bone morphogenetic protein 4 stimulates attachment of neurospheres and astrogenesis of neural stem cells in neurospheres via phosphatidylinositol 3 kinase-mediated upregulation of N-cadherin.
Kim MY, Kaduwal S, Yang DH, Choi KY
Neuroscience. 2010
PubMed ID: 20638445
Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program.
Bruce SJ, Butterfield NC, Metzis V, Town L, McGlinn E, Wicking C
J Biol Chem. 2010
PubMed ID: 20576618
Gene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse.
Snyder EM, Small CL, Bomgardner D, Xu B, Evanoff R, Griswold MD, Hinton BT
Dev Dyn. 2010
PubMed ID: 20652947
Spatiotemporal distribution and function of N-cadherin in postnatal Schwann cells: A matter of adhesion?
Corell M, Wicher G, Limbach C, Kilimann MW, Colman DR, Svenningsen AF
J Neurosci Res. 2010
PubMed ID: 20623533
Different regulation of N-cadherin and cadherin-11 in rat hippocampus.
Bartelt-Kirbach B, Langer-Fischer K, Golenhofen N
Cell Commun Adhes. 2010
PubMed ID: 21250828
[Expression and significance of N-cadherin and β-catenin protein in osteosarcoma].
Yang JZ, Zhang XH, Liu JR, Ding Y, Gao F, Wang Y
Zhonghua Zhong Liu Za Zhi. 2010
PubMed ID: 21122409
Role of neural-cadherin in early osteoblastic differentiation of human bone marrow stromal cells cocultured with human umbilical vein endothelial cells.
Li H, Daculsi R, Grellier M, Bareille R, Bourget C, Amedee J
Am J Physiol Cell Physiol. 2010
PubMed ID: 20664068
N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.
Di Benedetto A, Watkins M, Grimston S, Salazar V, Donsante C, Mbalaviele G, Radice GL, Civitelli R
J Cell Sci. 2010
PubMed ID: 20605916
Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells.
Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Nakamura Y, Gomei Y, Suda T
Blood. 2010
PubMed ID: 20427705
Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin.
Bozdagi O, Wang XB, Nikitczuk JS, Anderson TR, Bloss EB, Radice GL, Zhou Q, Benson DL, Huntley GW
J Neurosci. 2010
PubMed ID: 20668183
Epicardial spindle orientation controls cell entry into the myocardium.
Wu M, Smith CL, Hall JA, Lee I, Luby-Phelps K, Tallquist MD
Dev Cell. 2010
PubMed ID: 20643355
N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation.
Libusova L, Stemmler MP, Hierholzer A, Schwarz H, Kemler R
Development. 2010
PubMed ID: 20534673
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Mol Med. 2010
PubMed ID: 20379614
The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.
Wiley LA, Dattilo LK, Kang KB, Giovannini M, Beebe DC
Invest Ophthalmol Vis Sci. 2010
PubMed ID: 20181838
MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis.
Williams H, Johnson JL, Jackson CL, White SJ, George SJ
Cardiovasc Res. 2010
PubMed ID: 20139113
Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity.
Poore CP, Sundaram JR, Pareek TK, Fu A, Amin N, Mohamed NE, Zheng YL, Goh AX, Lai MK, Ip NY, Pant HC, Kesavapany S
J Neurosci. 2010
PubMed ID: 20573893
Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation.
Stan A, Pielarski KN, Brigadski T, Wittenmayer N, Fedorchenko O, Gohla A, Lessmann V, Dresbach T, Gottmann K
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20534458
N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer.
Jennbacken K, Tesan T, Wang W, Gustavsson H, Damber JE, Welén K
Endocr Relat Cancer. 2010
PubMed ID: 20233707
N-cadherin-dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth.
Tan ZJ, Peng Y, Song HL, Zheng JJ, Yu X
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20457910
The PX-RICS-14-3-3zeta/theta complex couples N-cadherin-beta-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum.
Nakamura T, Hayashi T, Mimori-Kiyosue Y, Sakaue F, Matsuura K, Iemura S, Natsume T, Akiyama T
J Biol Chem. 2010
PubMed ID: 20308060
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.
Uchiyama Y, Sakaguchi M, Terabayashi T, Inenaga T, Inoue S, Kobayashi C, Oshima N, Kiyonari H, Nakagata N, Sato Y, Sekiguchi K, Miki H, Araki E, Fujimura S, Tanaka SS, Nishinakamura R
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20439720
N-cadherin mediates plasticity-induced long-term spine stabilization.
Mendez P, De Roo M, Poglia L, Klauser P, Muller D
J Cell Biol. 2010
PubMed ID: 20440002
N- and E-cadherin expression in human ovarian and urogenital duct development.
Smith SR, Fulton N, Collins CS, Welsh M, Bayne RA, Coutts SM, Childs AJ, Anderson RA
Fertil Steril. 2010
PubMed ID: 19324354
Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Ishiyama N, Lee SH, Liu S, Li GY, Smith MJ, Reichardt LF, Ikura M
Cell. 2010
PubMed ID: 20371349
The prognostic value of cadherin switch in bladder cancer.
Jäger T, Becker M, Eisenhardt A, Tilki D, Tötsch M, Schmid KW, Romics I, Rübben H, Ergün S, Szarvas T
Oncol Rep. 2010
PubMed ID: 20204300
The protein tyrosine phosphatase PTP1B is required for efficient delivery of N-cadherin to the cell surface.
Hernández MV, Wehrendt DP, Arregui CO
Mol Biol Cell. 2010
PubMed ID: 20181825
Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin.
Gao L, McBeath R, Chen CS
Stem Cells. 2010
PubMed ID: 20082286
p120-Catenin is required for mouse vascular development.
Oas RG, Xiao K, Summers S, Wittich KB, Chiasson CM, Martin WD, Grossniklaus HE, Vincent PA, Reynolds AB, Kowalczyk AP
Circ Res. 2010
PubMed ID: 20110533
Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo.
Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N
Circ Res. 2010
PubMed ID: 20093627
Cortical neural precursors inhibit their own differentiation via N-cadherin maintenance of beta-catenin signaling.
Zhang J, Woodhead GJ, Swaminathan SK, Noles SR, McQuinn ER, Pisarek AJ, Stocker AM, Mutch CA, Funatsu N, Chenn A
Dev Cell. 2010
PubMed ID: 20230753
N-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblasts.
Lu M, Krauss RS
Proc Natl Acad Sci U S A. 2010
PubMed ID: 20160094
N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells.
Wein F, Pietsch L, Saffrich R, Wuchter P, Walenda T, Bork S, Horn P, Diehlmann A, Eckstein V, Ho AD, Wagner W
Stem Cell Res. 2010
PubMed ID: 20116358
The extracellular domains of E- and N-cadherin determine the scattered punctate localization in epithelial cells and the cytoplasmic domains modulate the localization.
Ozaki C, Obata S, Yamanaka H, Tominaga S, Suzuki ST
J Biochem. 2010
PubMed ID: 19919954
Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines.
Wallerand H, Cai Y, Wainberg ZA, Garraway I, Lascombe I, Nicolle G, Thiery JP, Bittard H, Radvanyi F, Reiter RR
Urol Oncol. 2010
PubMed ID: 19070520
Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation.
Adam O, Lavall D, Theobald K, Hohl M, Grube M, Ameling S, Sussman MA, Rosenkranz S, Kroemer HK, Schäfers HJ, Böhm M, Laufs U
J Am Coll Cardiol. 2010
PubMed ID: 20117462
[Role of N-cadherin in maintaining leukemic stem cell properties].
Zhi L, Wang L, Tian Z, Rao Q, Wang M, Wang JX
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010
PubMed ID: 20137108
Vang-like protein 2 and Rac1 interact to regulate adherens junctions.
Lindqvist M, Horn Z, Bryja V, Schulte G, Papachristou P, Ajima R, Dyberg C, Arenas E, Yamaguchi TP, Lagercrantz H, Ringstedt T
J Cell Sci. 2010
PubMed ID: 20067994
Which FGF ligands are involved in lens induction?
Smith AN, Radice G, Lang RA
Dev Biol. 2010
PubMed ID: 19913010
Epithelial N-cadherin and nuclear β-catenin are up-regulated during early development of human lung.
Kaarteenaho R, Lappi-Blanco E, Lehtonen S
BMC Dev Biol. 2010
PubMed ID: 21080917
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PLoS One. 2010
PubMed ID: 20634891
Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death.
Marchong MN, Yurkowski C, Ma C, Spencer C, Pajovic S, Gallie BL
PLoS Genet. 2010
PubMed ID: 20421947
[Expression of Twist, E-cadherin and N-cadherin in breast carcinoma and their clinical significance].
Ma YH, Wang K, Li L, Lu ZH, Chen J
Zhonghua Bing Li Xue Za Zhi. 2010
PubMed ID: 20388391
gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranes.
Frånberg J, Karlström H, Winblad B, Tjernberg LO, Frykman S
PLoS One. 2010
PubMed ID: 20333303
Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.
Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D
Development. 2010
PubMed ID: 20040491
Cadherin expression in gastrointestinal tract endometriosis: possible role in deep tissue invasion and development of malignancy.
Van Patten K, Parkash V, Jain D
Mod Pathol. 2010
PubMed ID: 19898423
Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos.
Hierholzer A, Kemler R
Dev Dyn. 2010
PubMed ID: 19705445
Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression.
Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Räsänen J, Vainio SJ
Cardiovasc Res. 2010
PubMed ID: 19622544
A cell polarity protein aPKClambda is required for eye lens formation and growth.
Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA
Dev Biol. 2009
PubMed ID: 19835853
Lebectin increases N-cadherin-mediated adhesion through PI3K/AKT pathway.
Sarray S, Siret C, Lehmann M, Marrakchi N, Luis J, El Ayeb M, André F
Cancer Lett. 2009
PubMed ID: 19501458
The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.
Kang W, Wong LC, Shi SH, Hébert JM
J Neurosci. 2009
PubMed ID: 19923290
N-cadherin mediates interaction between precursor cells in the subventricular zone and regulates further differentiation.
Yagita Y, Sakurai T, Tanaka H, Kitagawa K, Colman DR, Shan W
J Neurosci Res. 2009
PubMed ID: 19301425
Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43).
Sato M, Jiao Q, Honda T, Kurotani R, Toyota E, Okumura S, Takeya T, Minamisawa S, Lanier SM, Ishikawa Y
J Biol Chem. 2009
PubMed ID: 19723622
HNK-1 glyco-epitope regulates the stability of the glutamate receptor subunit GluR2 on the neuronal cell surface.
Morita I, Kakuda S, Takeuchi Y, Itoh S, Kawasaki N, Kizuka Y, Kawasaki T, Oka S
J Biol Chem. 2009
PubMed ID: 19729452
IGF-1 released by corneal epithelial cells induces up-regulation of N-cadherin in corneal fibroblasts.
Ko JA, Yanai R, Nishida T
J Cell Physiol. 2009
PubMed ID: 19530221
Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis.
Smith AN, Miller LA, Radice G, Ashery-Padan R, Lang RA
Development. 2009
PubMed ID: 19666824
MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex.
Weimer JM, Yokota Y, Stanco A, Stumpo DJ, Blackshear PJ, Anton ES
Development. 2009
PubMed ID: 19666823
Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis.
Rivera C, Yamben IF, Shatadal S, Waldof M, Robinson ML, Griep AE
Dev Dyn. 2009
PubMed ID: 19623611
N-cadherin/p120 catenin association at cell-cell contacts occurs in cholesterol-rich membrane domains and is required for RhoA activation and myogenesis.
Taulet N, Comunale F, Favard C, Charrasse S, Bodin S, Gauthier-Rouvière C
J Biol Chem. 2009
PubMed ID: 19546217
Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin.
Hartland SN, Murphy F, Aucott RL, Abergel A, Zhou X, Waung J, Patel N, Bradshaw C, Collins J, Mann D, Benyon RC, Iredale JP
Liver Int. 2009
PubMed ID: 19580633
Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation.
Downes M, François M, Ferguson C, Parton RG, Koopman P
Hum Mol Genet. 2009
PubMed ID: 19429912
Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch.
Shair KH, Schnegg CI, Raab-Traub N
Cancer Res. 2009
PubMed ID: 19584275
Effects of N-cadherin overexpression on the adhesion properties of embryonic stem cells.
Karabekian Z, Gillum ND, Wong EW, Sarvazyan N
Cell Adh Migr. 2009
PubMed ID: 19377287
Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.
Tang M, Miyamoto Y, Huang EJ
Development. 2009
PubMed ID: 19439492
Lineage-specific biology revealed by a finished genome assembly of the mouse.
Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X, Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y, Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R, Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K, Eichler EE, Ponting CP, Mouse Genome Sequencing Consortium
PLoS Biol. 2009
PubMed ID: 19468303
Unraveling the genetic landscape of bladder development in mice.
Price KL, Woolf AS, Long DA
J Urol. 2009
PubMed ID: 19303107
Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.
Rocha SF, Lopes SS, Gossler A, Henrique D
Dev Biol. 2009
PubMed ID: 19389377
Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.
Canova C, Hashibe M, Simonato L, Nelis M, Metspalu A, Lagiou P, Trichopoulos D, Ahrens W, Pigeot I, Merletti F, Richiardi L, Talamini R, Barzan L, Macfarlane GJ, Macfarlane TV, Holcátová I, Bencko V, Benhamou S, Bouchardy C, Kjaerheim K, Lowry R, Agudo A, Castellsagué X, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy CM, Marron M, Brennan P
Cancer Res. 2009
PubMed ID: 19339270
E-Cadherin regulates neural stem cell self-renewal.
Karpowicz P, Willaime-Morawek S, Balenci L, DeVeale B, Inoue T, van der Kooy D
J Neurosci. 2009
PubMed ID: 19321785
Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.
Barrionuevo F, Georg I, Scherthan H, Lécureuil C, Guillou F, Wegner M, Scherer G
Dev Biol. 2009
PubMed ID: 19124014
Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function.
Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Holländer GA
J Immunol. 2009
PubMed ID: 19234195
The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain.
Grinberg-Rashi H, Ofek E, Perelman M, Skarda J, Yaron P, Hajdúch M, Jacob-Hirsch J, Amariglio N, Krupsky M, Simansky DA, Ram Z, Pfeffer R, Galernter I, Steinberg DM, Ben-Dov I, Rechavi G, Izraeli S
Clin Cancer Res. 2009
PubMed ID: 19190132
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.
Pontoriero GF, Smith AN, Miller LA, Radice GL, West-Mays JA, Lang RA
Dev Biol. 2009
PubMed ID: 18996109
N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro.
Li K, He W, Lin N, Wang X, Fan QX
World J Gastroenterol. 2009
PubMed ID: 19222093
Protein phosphatase Dusp26 associates with KIF3 motor and promotes N-cadherin-mediated cell-cell adhesion.
Tanuma N, Nomura M, Ikeda M, Kasugai I, Tsubaki Y, Takagaki K, Kawamura T, Yamashita Y, Sato I, Sato M, Katakura R, Kikuchi K, Shima H
Oncogene. 2009
PubMed ID: 19043453
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H
J Proteome Res. 2009
PubMed ID: 19159218
beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells.
Nygren MK, Døsen-Dahl G, Stubberud H, Wälchli S, Munthe E, Rian E
Exp Hematol. 2009
PubMed ID: 19101069
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.
Haÿ E, Laplantine E, Geoffroy V, Frain M, Kohler T, Müller R, Marie PJ
Mol Cell Biol. 2009
PubMed ID: 19075000
N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
Mosnier JF, Kandel C, Cazals-Hatem D, Bou-Hanna C, Gournay J, Jarry A, Laboisse CL
Mod Pathol. 2009
PubMed ID: 18622386
Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Barr AJ, Ugochukwu E, Lee WH, King ON, Filippakopoulos P, Alfano I, Savitsky P, Burgess-Brown NA, Müller S, Knapp S
Cell. 2009
PubMed ID: 19167335
N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.
Haÿ E, Nouraud A, Marie PJ
PLoS One. 2009
PubMed ID: 20011526
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F
PLoS One. 2009
PubMed ID: 19865483
Mesangial cells connected by the N-cadherin-catenin system in the rat kidney.
Nameta M, Yaoita E, Kato N, Zhao L, Zhang Y, Fujinaka H, Xu B, Yoshida Y, Yamamoto T
Nephron Exp Nephrol. 2009
PubMed ID: 19546590
Expression of N-cadherin in esophageal squamous cell carcinoma and silencing expression of N-cadherin using RNA interference on invasiveness of EC9706 cells.
Li K, Wang X, He W, Lin N, Fan QX
Chin J Cancer. 2009
PubMed ID: 19448425
Global comparative transcriptome analysis of cartilage formation in vivo.
Cameron TL, Belluoccio D, Farlie PG, Brachvogel B, Bateman JF
BMC Dev Biol. 2009
PubMed ID: 19272164
Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex.
Ivaniutsin U, Chen Y, Mason JO, Price DJ, Pratt T
Neural Dev. 2009
PubMed ID: 19149881
Analysis of APC, alpha-, beta-catenins, and N-cadherin protein expression in aggressive fibromatosis (desmoid tumor).
Ferenc T, Wroński JW, Kopczyński J, Kulig A, Sidor M, Stalińska L, Dziki A, Sygut J
Pathol Res Pract. 2009
PubMed ID: 19124205
Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1.
Himes AD, Raetzman LT
Dev Biol. 2009
PubMed ID: 18996108
Essential role of glucose transporter GLUT3 for post-implantation embryonic development.
Schmidt S, Hommel A, Gawlik V, Augustin R, Junicke N, Florian S, Richter M, Walther DJ, Montag D, Joost HG, Schürmann A
J Endocrinol. 2009
PubMed ID: 18948350
MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation.
Dwivedi A, Slater SC, George SJ
Cardiovasc Res. 2009
PubMed ID: 18852254
Role of cell and matrix-bound VEGF isoforms in lens development.
Saint-Geniez M, Kurihara T, D'Amore PA
Invest Ophthalmol Vis Sci. 2009
PubMed ID: 18757513
EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin.
Rappl A, Piontek G, Schlegel J
J Cell Sci. 2008
PubMed ID: 19033391
Perlecan is critical for heart stability.
Sasse P, Malan D, Fleischmann M, Roell W, Gustafsson E, Bostani T, Fan Y, Kolbe T, Breitbach M, Addicks K, Welz A, Brem G, Hescheler J, Aszodi A, Costell M, Bloch W, Fleischmann BK
Cardiovasc Res. 2008
PubMed ID: 18694874
N-cadherin levels in endothelial cells are regulated by monolayer maturity and p120 availability.
Ferreri DM, Minnear FL, Yin T, Kowalczyk AP, Vincent PA
Cell Commun Adhes. 2008
PubMed ID: 18979298
Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.
Yu W, McDonnell K, Taketo MM, Bai CB
Development. 2008
PubMed ID: 18927156
Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures.
Walker JL, Menko AS, Khalil S, Rebustini I, Hoffman MP, Kreidberg JA, Kukuruzinska MA
Dev Dyn. 2008
PubMed ID: 18816447
Expression of E- and N-cadherin and clinicopathology in hepatocellular carcinoma.
Cho SB, Lee KH, Lee JH, Park SY, Lee WS, Park CH, Kim HS, Choi SK, Rew JS
Pathol Int. 2008
PubMed ID: 18801083
Trypanosoma cruzi alters adherens junctions in cardiomyocytes.
de Melo TG, Meirelles Mde N, Pereira MC
Microbes Infect. 2008
PubMed ID: 18778790
Signaling via the Tgf-beta type I receptor Alk5 in heart development.
Sridurongrit S, Larsson J, Schwartz R, Ruiz-Lozano P, Kaartinen V
Dev Biol. 2008
PubMed ID: 18718461
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition.
Hirano M, Hashimoto S, Yonemura S, Sabe H, Aizawa S
J Cell Biol. 2008
PubMed ID: 18794329
Differential requirement for beta-catenin in epithelial and fiber cells during lens development.
Cain S, Martinez G, Kokkinos MI, Turner K, Richardson RJ, Abud HE, Huelsken J, Robinson ML, de Iongh RU
Dev Biol. 2008
PubMed ID: 18652817
Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML
Genet Med. 2008
PubMed ID: 18978678
Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.
Wataya T, Ando S, Muguruma K, Ikeda H, Watanabe K, Eiraku M, Kawada M, Takahashi J, Hashimoto N, Sasai Y
Proc Natl Acad Sci U S A. 2008
PubMed ID: 18697938
Homotypic and endothelial cell adhesions via N-cadherin determine polarity and regulate migration of vascular smooth muscle cells.
Sabatini PJ, Zhang M, Silverman-Gavrila R, Bendeck MP, Langille BL
Circ Res. 2008
PubMed ID: 18617695
Hedgehog signaling is involved in development of the neocortex.
Komada M, Saitsu H, Kinboshi M, Miura T, Shiota K, Ishibashi M
Development. 2008
PubMed ID: 18614579
Potential role of N-cadherin in hepatocyte growth factor (HGF) mediated improvement of the cardiac function of dilated cardiomyopathy mice.
Tang Q, Shen D, Huang Z, Xiong R, Wu H, Huang J, Feng S, Niu P, Yang L, Bian Z
Int J Cardiol. 2008
PubMed ID: 18495274
Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, Thinakaran G
J Biol Chem. 2008
PubMed ID: 18456655
Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool.
Solberg N, Machon O, Krauss S
Dev Dyn. 2008
PubMed ID: 18521945
Neural cadherin overexpression is a predictive marker for early postoperative recurrence in hepatocellular carcinoma patients.
Seo DD, Lee HC, Kim HJ, Min HJ, Kim KM, Lim YS, Chung YH, Lee YS, Suh DJ, Yu E, Chun SY
J Gastroenterol Hepatol. 2008
PubMed ID: 17944884
Nedd1 expression as a marker of dynamic centrosomal localization during mouse embryonic development.
Manning JA, Colussi PA, Koblar SA, Kumar S
Histochem Cell Biol. 2008
PubMed ID: 18239929
Is N-cadherin expression important in ductal carcinoma?
King JA, Shevde LA, Ofori-Acquah S, Watkins G, Jiang WG
South Med J. 2008
PubMed ID: 18414176
alphaE-catenin is not a significant regulator of beta-catenin signaling in the developing mammalian brain.
Lien WH, Klezovitch O, Null M, Vasioukhin V
J Cell Sci. 2008
PubMed ID: 18397997
Sox9 is required for invagination of the otic placode in mice.
Barrionuevo F, Naumann A, Bagheri-Fam S, Speth V, Taketo MM, Scherer G, Neubüser A
Dev Biol. 2008
PubMed ID: 18377888
Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.
Suzuki A, Sekiya S, Büscher D, Izpisúa Belmonte JC, Taniguchi H
Development. 2008
PubMed ID: 18356246
Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.
Spassky N, Han YG, Aguilar A, Strehl L, Besse L, Laclef C, Ros MR, Garcia-Verdugo JM, Alvarez-Buylla A
Dev Biol. 2008
PubMed ID: 18353302
Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Agarwal SK, Lee DM, Kiener HP, Brenner MB
Arthritis Rheum. 2008
PubMed ID: 18383368
Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1.
Shintani Y, Fukumoto Y, Chaika N, Svoboda R, Wheelock MJ, Johnson KR
J Cell Biol. 2008
PubMed ID: 18362184
Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype.
Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA
Dev Dyn. 2008
PubMed ID: 18224708
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Li J, Levin MD, Xiong Y, Petrenko N, Patel VV, Radice GL
J Mol Cell Cardiol. 2008
PubMed ID: 18201716
Compartmentalization in membrane rafts defines a pool of N-cadherin associated with catenins and not engaged in cell-cell junctions in melanoma cells.
Rossier-Pansier L, Baruthio F, Rüegg C, Mariotti A
J Cell Biochem. 2008
PubMed ID: 17668445
Differential expression of neural-cadherin in pulmonary epithelial tumours.
Zynger DL, Dimov ND, Ho LC, Laskin WB, Yeldandi AV
Histopathology. 2008
PubMed ID: 18269586
N-cadherin expression in palisade nerve endings of rat vellus hairs.
Kaidoh T, Inoué T
J Comp Neurol. 2008
PubMed ID: 18067145
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo.
Andersson ER, Prakash N, Cajanek L, Minina E, Bryja V, Bryjova L, Yamaguchi TP, Hall AC, Wurst W, Arenas E
PLoS ONE. 2008
PubMed ID: 18953410
Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance.
Manuel M, Pratt T, Liu M, Jeffery G, Price DJ
BMC Dev Biol. 2008
PubMed ID: 18507827
Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders.
Bakkaloglu B, O'Roak BJ, Louvi A, Gupta AR, Abelson JF, Morgan TM, Chawarska K, Klin A, Ercan-Sencicek AG, Stillman AA, Tanriover G, Abrahams BS, Duvall JA, Robbins EM, Geschwind DH, Biederer T, Gunel M, Lifton RP, State MW
Am J Hum Genet. 2008
PubMed ID: 18179895
Cadherin-8 and N-cadherin differentially regulate pre- and postsynaptic development of the hippocampal mossy fiber pathway.
Bekirov IH, Nagy V, Svoronos A, Huntley GW, Benson DL
Hippocampus. 2008
PubMed ID: 18064706
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
Akintola AD, Crislip ZL, Catania JM, Chen G, Zimmer WE, Burghardt RC, Parrish AR
Am J Physiol Renal Physiol. 2008
PubMed ID: 17959753
Nucleation and growth of cadherin adhesions.
Lambert M, Thoumine O, Brevier J, Choquet D, Riveline D, Mège RM
Exp Cell Res. 2007
PubMed ID: 17765222
Modulation of human Kv1.5 channel kinetics by N-cadherin.
Koutsouki E, Lam RS, Seebohm G, Ureche ON, Ureche L, Baltaev R, Lang F
Biochem Biophys Res Commun. 2007
PubMed ID: 17868645
Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases.
Yasuda S, Tanaka H, Sugiura H, Okamura K, Sakaguchi T, Tran U, Takemiya T, Mizoguchi A, Yagita Y, Sakurai T, De Robertis EM, Yamagata K
Neuron. 2007
PubMed ID: 17988630
A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.
Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S
Dev Biol. 2007
PubMed ID: 17916349
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.
Gustafson-Wagner EA, Sinn HW, Chen YL, Wang DZ, Reiter RS, Lin JL, Yang B, Williamson RA, Chen J, Lin CI, Lin JJ
Am J Physiol Heart Circ Physiol. 2007
PubMed ID: 17766470
N-cadherin engagement provides a dominant stop signal for the migration of MDA-MB-468 breast carcinoma cells.
Potthoff S, Entschladen F, Niggemann B, Zaenker KS, Lang K
Breast Cancer Res Treat. 2007
PubMed ID: 17171299
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.
Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM
Nat Genet. 2007
PubMed ID: 17767158
SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis.
Rizzoti K, Lovell-Badge R
Development. 2007
PubMed ID: 17728342
The green tea compound, (-)-epigallocatechin-3-gallate downregulates N-cadherin and suppresses migration of bladder carcinoma cells.
Rieger-Christ KM, Hanley R, Lodowsky C, Bernier T, Vemulapalli P, Roth M, Kim J, Yee AS, Le SM, Marie PJ, Libertino JA, Summerhayes IC
J Cell Biochem. 2007
PubMed ID: 17348027
Trio controls the mature organization of neuronal clusters in the hindbrain.
Backer S, Hidalgo-Sánchez M, Offner N, Portales-Casamar E, Debant A, Fort P, Gauthier-Rouvière C, Bloch-Gallego E
J Neurosci. 2007
PubMed ID: 17898204
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome.
Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O, Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL, Schmidt EE
Free Radic Biol Med. 2007
PubMed ID: 17697936
N-cadherin regulates cytoskeletally associated IQGAP1/ERK signaling and memory formation.
Schrick C, Fischer A, Srivastava DP, Tronson NC, Penzes P, Radulovic J
Neuron. 2007
PubMed ID: 17785185
Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.
Nechiporuk T, Fernandez TE, Vasioukhin V
Dev Cell. 2007
PubMed ID: 17765678
Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.
Kiel MJ, Radice GL, Morrison SJ
Cell Stem Cell. 2007
PubMed ID: 18371351
PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development.
Hayashi T, Okabe T, Nasu-Nishimura Y, Sakaue F, Ohwada S, Matsuura K, Akiyama T, Nakamura T
Genes Cells. 2007
PubMed ID: 17663722
Cadherins are regulated by Ep-CAM via phosphaditylinositol-3 kinase.
Winter MJ, Cirulli V, Briaire-de Bruijn IH, Litvinov SV
Mol Cell Biochem. 2007
PubMed ID: 17646933
Cadherin inhibition of beta-catenin signaling regulates the proliferation and differentiation of neural precursor cells.
Noles SR, Chenn A
Mol Cell Neurosci. 2007
PubMed ID: 17553695
Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization.
Phillips HM, Rhee HJ, Murdoch JN, Hildreth V, Peat JD, Anderson RH, Copp AJ, Chaudhry B, Henderson DJ
Circ Res. 2007
PubMed ID: 17556662
Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression.
Yang Z, Zhang X, Gang H, Li X, Li Z, Wang T, Han J, Luo T, Wen F, Wu X
Biochem Biophys Res Commun. 2007
PubMed ID: 17512904
N-cadherin is essential for retinoic acid-mediated cardiomyogenic differentiation in mouse embryonic stem cells.
Bugorsky R, Perriard JC, Vassalli G
Eur J Histochem. 2007
PubMed ID: 17921113
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.
Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N
Nat Neurosci. 2007
PubMed ID: 17589506
Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules.
Wang W, Mullikin-Kilpatrick D, Crandall JE, Gronostajski RM, Litwack ED, Kilpatrick DL
J Neurosci. 2007
PubMed ID: 17553984
The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo.
Lee JD, Silva-Gagliardi NF, Tepass U, McGlade CJ, Anderson KV
Development. 2007
PubMed ID: 17507402
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.
Ma X, Bao J, Adelstein RS
Mol Biol Cell. 2007
PubMed ID: 17429076
Increased resistance to a farnesyltransferase inhibitor by N-cadherin expression in Bcr/Abl-P190 lymphoblastic leukemia cells.
Zhang B, Groffen J, Heisterkamp N
Leukemia. 2007
PubMed ID: 17392819
GSK3beta activity modifies the localization and function of presenilin 1.
Uemura K, Kuzuya A, Shimozono Y, Aoyagi N, Ando K, Shimohama S, Kinoshita A
J Biol Chem. 2007
PubMed ID: 17389597
Cadherin expression in the developing mouse olfactory system.
Akins MR, Benson DL, Greer CA
J Comp Neurol. 2007
PubMed ID: 17278136
NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility.
Theisen CS, Wahl JK, Johnson KR, Wheelock MJ
Mol Biol Cell. 2007
PubMed ID: 17229887
N-cadherin mediates cortical organization in the mouse brain.
Kadowaki M, Nakamura S, Machon O, Krauss S, Radice GL, Takeichi M
Dev Biol. 2007
PubMed ID: 17222817
IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli.
Sharma M, Henderson BR
J Biol Chem. 2007
PubMed ID: 17255093
The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion.
McLaughlin ME, Kruger GM, Slocum KL, Crowley D, Michaud NA, Huang J, Magendantz M, Jacks T
Proc Natl Acad Sci U S A. 2007
PubMed ID: 17360635
CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse.
Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y
Dev Biol. 2007
PubMed ID: 17067568
Regulation of N-cadherin-based cell-cell interaction by JSAP1 scaffold in PC12h cells.
Bayarsaikhan M, Takino T, Gantulga D, Sato H, Ito T, Yoshioka K
Biochem Biophys Res Commun. 2007
PubMed ID: 17188238
N-Cadherin is expressed by putative stem/progenitor cells and melanocytes in the human limbal epithelial stem cell niche.
Hayashi R, Yamato M, Sugiyama H, Sumide T, Yang J, Okano T, Tano Y, Nishida K
Stem Cells. 2007
PubMed ID: 17008425
Switch of cadherin expression from E- to N-type during the activation of rat hepatic stellate cells.
Lim YS, Lee HC, Lee HS
Histochem Cell Biol. 2007
PubMed ID: 16955247
Large-scale in silico mapping of complex quantitative traits in inbred mice.
Liu P, Vikis H, Lu Y, Wang D, You M
PLoS ONE. 2007
PubMed ID: 17653278
Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm.
Kan NG, Stemmler MP, Junghans D, Kanzler B, de Vries WN, Dominis M, Kemler R
Development. 2007
PubMed ID: 17138661
N-cadherin is an in vivo substrate for protein tyrosine phosphatase sigma (PTPsigma) and participates in PTPsigma-mediated inhibition of axon growth.
Siu R, Fladd C, Rotin D
Mol Cell Biol. 2007
PubMed ID: 17060446
Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model.
Hecht J, Seitz V, Urban M, Wagner F, Robinson PN, Stiege A, Dieterich C, Kornak U, Wilkening U, Brieske N, Zwingman C, Kidess A, Stricker S, Mundlos S
Gene Expr Patterns. 2007
PubMed ID: 16829211
Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression.
Shintani Y, Hollingsworth MA, Wheelock MJ, Johnson KR
Cancer Res. 2006
PubMed ID: 17178870
A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells.
Iden S, Rehder D, August B, Suzuki A, Wolburg-Buchholz K, Wolburg H, Ohno S, Behrens J, Vestweber D, Ebnet K
EMBO Rep. 2006
PubMed ID: 17057644
Accentuated ovariectomy-induced bone loss and altered osteogenesis in heterozygous N-cadherin null mice.
Lai CF, Cheng SL, Mbalaviele G, Donsante C, Watkins M, Radice GL, Civitelli R
J Bone Miner Res. 2006
PubMed ID: 17002573
Traction forces exerted through N-cadherin contacts.
Ganz A, Lambert M, Saez A, Silberzan P, Buguin A, Mège RM, Ladoux B
Biol Cell. 2006
PubMed ID: 16895521
N-cadherin is required for neural crest remodeling of the cardiac outflow tract.
Luo Y, High FA, Epstein JA, Radice GL
Dev Biol. 2006
PubMed ID: 17014840
Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development.
Fu X, Sun H, Klein WH, Mu X
Dev Biol. 2006
PubMed ID: 16959241
A specific cadherin phenotype may characterise the disseminating yet non-metastatic behaviour of pseudomyxoma peritonei.
Bibi R, Pranesh N, Saunders MP, Wilson MS, O'dwyer ST, Stern PL, Renehan AG
Br J Cancer. 2006
PubMed ID: 17031402
VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin.
Gavard J, Gutkind JS
Nat Cell Biol. 2006
PubMed ID: 17060906
Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.
Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T, Shiojiri N
Development. 2006
PubMed ID: 17021047
Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).
Besco JA, Hooft van Huijsduijnen R, Frostholm A, Rotter A
Brain Res. 2006
PubMed ID: 16973135
The role of N-cadherin, MCAM and beta3 integrin in melanoma progression, proliferation, migration and invasion.
Watson-Hurst K, Becker D
Cancer Biol Ther. 2006
PubMed ID: 16969099
Role of N-cadherin in Schwann cell precursors of growing nerves.
Wanner IB, Guerra NK, Mahoney J, Kumar A, Wood PM, Mirsky R, Jessen KR
Glia. 2006
PubMed ID: 16886205
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Cappello S, Attardo A, Wu X, Iwasato T, Itohara S, Wilsch-Bräuninger M, Eilken HM, Rieger MA, Schroeder TT, Huttner WB, Brakebusch C, Götz M
Nat Neurosci. 2006
PubMed ID: 16892058
BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions.
Bamji SX, Rico B, Kimes N, Reichardt LF
J Cell Biol. 2006
PubMed ID: 16831887
Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin.
Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Bito H, Ninomiya H, Sugimoto H, Kinoshita A, Shimohama S
Biochem Biophys Res Commun. 2006
PubMed ID: 16707106
The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons.
Huang J, Sakai R, Furuichi T
Mol Biol Cell. 2006
PubMed ID: 16687575
Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.
Shintani Y, Wheelock MJ, Johnson KR
Mol Biol Cell. 2006
PubMed ID: 16624865
N-cadherin mediates nitric oxide-induced neurogenesis in young and retired breeder neurospheres.
Chen J, Zacharek A, Li Y, Li A, Wang L, Katakowski M, Roberts C, Lu M, Chopp M
Neuroscience. 2006
PubMed ID: 16580782
N-cadherin transsynaptically regulates short-term plasticity at glutamatergic synapses in embryonic stem cell-derived neurons.
Jüngling K, Eulenburg V, Moore R, Kemler R, Lessmann V, Gottmann K
J Neurosci. 2006
PubMed ID: 16807326
Differential interactions between transforming growth factor-beta3/TbetaR1, TAB1, and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion.
Xia W, Mruk DD, Lee WM, Cheng CY
J Biol Chem. 2006
PubMed ID: 16617054
Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development.
Bäumer S, Keller L, Holtmann A, Funke R, August B, Gamp A, Wolburg H, Wolburg-Buchholz K, Deutsch U, Vestweber D
Blood. 2006
PubMed ID: 16514057
Differential expression of N-cadherin and E-cadherin in normal human tissues.
Tsuchiya B, Sato Y, Kameya T, Okayasu I, Mukai K
Arch Histol Cytol. 2006
PubMed ID: 16819153
Midline radial glia translocation and corpus callosum formation require FGF signaling.
Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM
Nat Neurosci. 2006
PubMed ID: 16715082
N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption.
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK
Mol Cell Biol. 2006
PubMed ID: 16705170
Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes.
Heanue TA, Pachnis V
Proc Natl Acad Sci U S A. 2006
PubMed ID: 16632597
N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors.
Lascombe I, Clairotte A, Fauconnet S, Bernardini S, Wallerand H, Kantelip B, Bittard H
Clin Cancer Res. 2006
PubMed ID: 16675571
Anti-apoptotic N-cadherin signaling and its prognostic implication in human hepatocellular carcinomas.
Gwak GY, Yoon JH, Yu SJ, Park SC, Jang JJ, Lee KB, Lee SH, Lee SM, Shin CS, Suh KS, Lee HS
Oncol Rep. 2006
PubMed ID: 16596172
Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.
Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
Development. 2006
PubMed ID: 16571631
Epigenetic silencing of E- and N-cadherins in the stroma of mouse thymic lymphomas.
de Yzaguirre MM, Hernández JS, Navarro PF, Nieva PL, Herranz M, Fraga MF, Esteller M, Juarranz A, Fernández-Piqueras J
Carcinogenesis. 2006
PubMed ID: 16377805
Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves.
Chen JW, Zhou B, Yu QC, Shin SJ, Jiao K, Schneider MD, Baldwin HS, Bergelson JM
Circ Res. 2006
PubMed ID: 16543498
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T
PLoS Biol. 2006
PubMed ID: 16602821
N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes.
Matsuda T, Fujio Y, Nariai T, Ito T, Yamane M, Takatani T, Takahashi K, Azuma J
J Mol Cell Cardiol. 2006
PubMed ID: 16515795
alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.
Lien WH, Klezovitch O, Fernandez TE, Delrow J, Vasioukhin V
Science. 2006
PubMed ID: 16543460
Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells.
Qi J, Wang J, Romanyuk O, Siu CH
Mol Biol Cell. 2006
PubMed ID: 16371504
Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity.
Ito M, Maruyama T, Saito N, Koganei S, Yamamoto K, Matsumoto N
J Exp Med. 2006
PubMed ID: 16461340
Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1.
Yang CK, Kim JH, Li H, Stallcup MR
J Biol Chem. 2006
PubMed ID: 16344550
Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.
Seo KW, Wang Y, Kokubo H, Kettlewell JR, Zarkower DA, Johnson RL
Dev Biol. 2006
PubMed ID: 16387292
Regulation of N-cadherin dynamics at neuronal contacts by ligand binding and cytoskeletal coupling.
Thoumine O, Lambert M, Mège RM, Choquet D
Mol Biol Cell. 2006
PubMed ID: 16319177
N-cadherin switching occurs in high Gleason grade prostate cancer.
Jaggi M, Nazemi T, Abrahams NA, Baker JJ, Galich A, Smith LM, Balaji KC
Prostate. 2006
PubMed ID: 16173043
Ultrastructural analysis of development of myocardium in calreticulin-deficient mice.
Lozyk MD, Papp S, Zhang X, Nakamura K, Michalak M, Opas M
BMC Dev Biol. 2006
PubMed ID: 17112388
Soluble N-cadherin fragment promotes angiogenesis.
Derycke L, Morbidelli L, Ziche M, De Wever O, Bracke M, Van Aken E
Clin Exp Metastasis. 2006
PubMed ID: 17028923
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S
Genome Res. 2006
PubMed ID: 16344560
Dominant negative N-cadherin inhibits osteoclast differentiation by interfering with beta-catenin regulation of RANKL, independent of cell-cell adhesion.
Shin CS, Her SJ, Kim JA, Kim DH, Kim SW, Kim SY, Kim HS, Park KH, Kim JG, Kitazawa R, Cheng SL, Civitelli R
J Bone Miner Res. 2005
PubMed ID: 16294273
N-cadherin expression in breast cancer: correlation with an aggressive histologic variant--invasive micropapillary carcinoma.
Nagi C, Guttman M, Jaffer S, Qiao R, Keren R, Triana A, Li M, Godbold J, Bleiweiss IJ, Hazan RB
Breast Cancer Res Treat. 2005
PubMed ID: 16258702
Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.
Hung SP, Hsu JR, Lo CP, Huang HJ, Wang JP, Chen ST
J Cell Biochem. 2005
PubMed ID: 16149052
Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone.
Ajioka I, Nakajima K
Brain Res Dev Brain Res. 2005
PubMed ID: 16185771
Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina.
Koike C, Nishida A, Akimoto K, Nakaya MA, Noda T, Ohno S, Furukawa T
J Neurosci. 2005
PubMed ID: 16267237
N-cadherin deficiency impairs pericyte recruitment, and not endothelial differentiation or sprouting, in embryonic stem cell-derived angiogenesis.
Tillet E, Vittet D, Féraud O, Moore R, Kemler R, Huber P
Exp Cell Res. 2005
PubMed ID: 16202998
Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.
Olsen O, Moore KA, Fukata M, Kazuta T, Trinidad JC, Kauer FW, Streuli M, Misawa H, Burlingame AL, Nicoll RA, Bredt DS
J Cell Biol. 2005
PubMed ID: 16186258
DNA sequence and analysis of human chromosome 18.
Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Abouelleil A, Allen NR, Anderson S, Bloom T, Bugalter B, Butler J, Cook A, DeCaprio D, Engels R, Garber M, Gnirke A, Hafez N, Hall JL, Norman CH, Itoh T, Jaffe DB, Kuroki Y, Lehoczky J, Lui A, Macdonald P, Mauceli E, Mikkelsen TS, Naylor JW, Nicol R, Nguyen C, Noguchi H, O'Leary SB, O'Neill K, Piqani B, Smith CL, Talamas JA, Topham K, Totoki Y, Toyoda A, Wain HM, Young SK, Zeng Q, Zimmer AR, Fujiyama A, Hattori M, Birren BW, Sakaki Y, Lander ES
Nature. 2005
PubMed ID: 16177791
Antisense transcription in the mammalian transcriptome.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, RIKEN Genome Exploration Research Group, Genome Science Group (Genome Network Project Core Group), FANTOM Consortium
Science. 2005
PubMed ID: 16141073
The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science. 2005
PubMed ID: 16141072
Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis.
Li J, Patel VV, Kostetskii I, Xiong Y, Chu AF, Jacobson JT, Yu C, Morley GE, Molkentin JD, Radice GL
Circ Res. 2005
PubMed ID: 16100040
Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).
Amanchy R, Kalume DE, Iwahori A, Zhong J, Pandey A
J Proteome Res. 2005
PubMed ID: 16212419
Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.
Kim YJ, Sauer C, Testa K, Wahl JK, Svoboda RA, Johnson KR, Wheelock MJ, Knudsen KA
J Cell Sci. 2005
PubMed ID: 16091424
Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway.
Qi J, Chen N, Wang J, Siu CH
Mol Biol Cell. 2005
PubMed ID: 15987741
Effect of N-cadherin misexpression by the mammary epithelium in mice.
Knudsen KA, Sauer C, Johnson KR, Wheelock MJ
J Cell Biochem. 2005
PubMed ID: 15838877
Adhesion signaling by a novel mitotic substrate of src kinases.
Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM
Oncogene. 2005
PubMed ID: 16007225
Differential expression of individual gamma-protocadherins during mouse brain development.
Frank M, Ebert M, Shan W, Phillips GR, Arndt K, Colman DR, Kemler R
Mol Cell Neurosci. 2005
PubMed ID: 15964765
Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells.
Gorski JA, Gomez LL, Scott JD, Dell'Acqua ML
Mol Biol Cell. 2005
PubMed ID: 15930126
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Yuan X, Zhou Y, Casanova E, Chai M, Kiss E, Gröne HJ, Schütz G, Grummt I
Mol Cell. 2005
PubMed ID: 15989966
Close encounters: regulation of vertebrate skeletal myogenesis by cell-cell contact.
Krauss RS, Cole F, Gaio U, Takaesu G, Zhang W, Kang JS
J Cell Sci. 2005
PubMed ID: 15923648
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
Wei CJ, Francis R, Xu X, Lo CW
J Biol Chem. 2005
PubMed ID: 15741167
Association of Csk to VE-cadherin and inhibition of cell proliferation.
Baumeister U, Funke R, Ebnet K, Vorschmitt H, Koch S, Vestweber D
EMBO J. 2005
PubMed ID: 15861137
Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.
Smalley KS, Brafford P, Haass NK, Brandner JM, Brown E, Herlyn M
Am J Pathol. 2005
PubMed ID: 15855653
The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.
Teng J, Rai T, Tanaka Y, Takei Y, Nakata T, Hirasawa M, Kulkarni AB, Hirokawa N
Nat Cell Biol. 2005
PubMed ID: 15834408
N-cadherin-dependent cell-cell contacts promote human saphenous vein smooth muscle cell survival.
Koutsouki E, Beeching CA, Slater SC, Blaschuk OW, Sala-Newby GB, George SJ
Arterioscler Thromb Vasc Biol. 2005
PubMed ID: 15774907
N-RAP expression during mouse heart development.
Lu S, Borst DE, Horowits R
Dev Dyn. 2005
PubMed ID: 15765519
Gonadotropins regulate N-cadherin-mediated human ovarian surface epithelial cell survival at both post-translational and transcriptional levels through a cyclic AMP/protein kinase A pathway.
Pon YL, Auersperg N, Wong AS
J Biol Chem. 2005
PubMed ID: 15701645
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.
Luo Y, Radice GL
J Cell Biol. 2005
PubMed ID: 15809310
The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Willnow T, Antignac C, Brändli A, Christensen E, Cox R, Davidson D, Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A, Meij I
Organogenesis. 2005
PubMed ID: 19521566
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses.
Dunah AW, Hueske E, Wyszynski M, Hoogenraad CC, Jaworski J, Pak DT, Simonetta A, Liu G, Sheng M
Nat Neurosci. 2005
PubMed ID: 15750591
Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells.
Sheets SM, Potempa J, Travis J, Casiano CA, Fletcher HM
Infect Immun. 2005
PubMed ID: 15731052
Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition.
Maeda M, Johnson KR, Wheelock MJ
J Cell Sci. 2005
PubMed ID: 15713751
Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme.
Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H
Development. 2005
PubMed ID: 15689381
ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling.
Reiss K, Maretzky T, Ludwig A, Tousseyn T, de Strooper B, Hartmann D, Saftig P
EMBO J. 2005
PubMed ID: 15692570
Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure.
Kostetskii I, Li J, Xiong Y, Zhou R, Ferrari VA, Patel VV, Molkentin JD, Radice GL
Circ Res. 2005
PubMed ID: 15662031
N-cadherin differentially determines Schwann cell and olfactory ensheathing cell adhesion and migration responses upon contact with astrocytes.
Fairless R, Frame MC, Barnett SC
Mol Cell Neurosci. 2005
PubMed ID: 15691707
N-cadherin is not essential for limb mesenchymal chondrogenesis.
Luo Y, Kostetskii I, Radice GL
Dev Dyn. 2005
PubMed ID: 15614770
Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome Res. 2005
PubMed ID: 15632090
Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts.
Le Mée S, Fromigué O, Marie PJ
Exp Cell Res. 2005
PubMed ID: 15541732
Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis.
Lui WY, Mruk DD, Cheng CY
J Cell Physiol. 2005
PubMed ID: 15389538
Cadherin activity is required for activity-induced spine remodeling.
Okamura K, Tanaka H, Yagita Y, Saeki Y, Taguchi A, Hiraoka Y, Zeng LH, Colman DR, Miki N
J Cell Biol. 2004
PubMed ID: 15569714
Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P
Nat Methods. 2004
PubMed ID: 15782199
N-cadherin as an invasion promoter: a novel target for antitumor therapy?
Cavallaro U
Curr Opin Investig Drugs. 2004
PubMed ID: 15648948
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation.
Hatakeyama J, Bessho Y, Katoh K, Ookawara S, Fujioka M, Guillemot F, Kageyama R
Development. 2004
PubMed ID: 15496443
Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage.
Kii I, Amizuka N, Shimomura J, Saga Y, Kudo A
J Bone Miner Res. 2004
PubMed ID: 15476585
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann KS, Grund C, Huelsken J, Behrend M, Erdmann B, Franke WW, Birchmeier W
J Cell Biol. 2004
PubMed ID: 15479741
Correlation of N-cadherin expression in high grade gliomas with tissue invasion.
Asano K, Duntsch CD, Zhou Q, Weimar JD, Bordelon D, Robertson JH, Pourmotabbed T
J Neurooncol. 2004
PubMed ID: 15527101
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Morrin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J, MGC Project Team
Genome Res. 2004
PubMed ID: 15489334
Cortactin associates with N-cadherin adhesions and mediates intercellular adhesion strengthening in fibroblasts.
El Sayegh TY, Arora PD, Laschinger CA, Lee W, Morrison C, Overall CM, Kapus A, McCulloch CA
J Cell Sci. 2004
PubMed ID: 15383621
Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization.
Paik JH, Skoura A, Chae SS, Cowan AE, Han DK, Proia RL, Hla T
Genes Dev. 2004
PubMed ID: 15371328
Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.
Malhotra JD, Thyagarajan V, Chen C, Isom LL
J Biol Chem. 2004
PubMed ID: 15272007
Neoexpression of N-cadherin in E-cadherin positive colon cancers.
Rosivatz E, Becker I, Bamba M, Schott C, Diebold J, Mayr D, Höfler H, Becker KF
Int J Cancer. 2004
PubMed ID: 15252840
Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding.
De Wever O, Westbroek W, Verloes A, Bloemen N, Bracke M, Gespach C, Bruyneel E, Mareel M
J Cell Sci. 2004
PubMed ID: 15331629
Contacts between the commissural axons and the floor plate cells are mediated by nectins.
Okabe N, Shimizu K, Ozaki-Kuroda K, Nakanishi H, Morimoto K, Takeuchi M, Katsumaru H, Murakami F, Takai Y
Dev Biol. 2004
PubMed ID: 15328010
N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma.
Yoshinaga K, Inoue H, Utsunomiya T, Sonoda H, Masuda T, Mimori K, Tanaka Y, Mori M
Clin Cancer Res. 2004
PubMed ID: 15355896
N-cadherin activation substitutes for the cell contact control in cell cycle arrest and myogenic differentiation: involvement of p120 and beta-catenin.
Gavard J, Marthiens V, Monnet C, Lambert M, Mège RM
J Biol Chem. 2004
PubMed ID: 15194693
Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion.
Yano H, Mazaki Y, Kurokawa K, Hanks SK, Matsuda M, Sabe H
J Cell Biol. 2004
PubMed ID: 15263022
PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations.
Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK
EMBO J. 2004
PubMed ID: 15192701
N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma.
Nakajima S, Doi R, Toyoda E, Tsuji S, Wada M, Koizumi M, Tulachan SS, Ito D, Kami K, Mori T, Kawaguchi Y, Fujimoto K, Hosotani R, Imamura M
Clin Cancer Res. 2004
PubMed ID: 15217949
Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis.
Castro CH, Shin CS, Stains JP, Cheng SL, Sheikh S, Mbalaviele G, Szejnfeld VL, Civitelli R
J Cell Sci. 2004
PubMed ID: 15169841
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.
Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW
Nat Biotechnol. 2004
PubMed ID: 15146197
Cadherin switch in tumor progression.
Hazan RB, Qiao R, Keren R, Badano I, Suyama K
Ann N Y Acad Sci. 2004
PubMed ID: 15153430
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium
Nature. 2004
PubMed ID: 15057822
Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.
Nastasi T, Bongiovanni A, Campos Y, Mann L, Toy JN, Bostrom J, Rottier R, Hahn C, Conaway JW, Harris AJ, D'Azzo A
Dev Cell. 2004
PubMed ID: 14960280
Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways.
Gavard J, Lambert M, Grosheva I, Marthiens V, Irinopoulou T, Riou JF, Bershadsky A, Mège RM
J Cell Sci. 2004
PubMed ID: 14657280
Cadherin expression pattern in melanocytic tumors more likely depends on the melanocyte environment than on tumor cell progression.
Krengel S, Grotelüschen F, Bartsch S, Tronnier M
J Cutan Pathol. 2004
PubMed ID: 14675278
N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways.
Guo HB, Lee I, Kamar M, Pierce M
J Biol Chem. 2003
PubMed ID: 14561752
Two regions of cadherin cytoplasmic domains are involved in suppressing motility of a mammary carcinoma cell line.
Fedor-Chaiken M, Meigs TE, Kaplan DD, Brackenbury R
J Biol Chem. 2003
PubMed ID: 14559901
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis.
Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY, Jan YN
Neuron. 2003
PubMed ID: 14687546
A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells.
Straub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M, Franke WW
J Cell Sci. 2003
PubMed ID: 14625392
Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis.
Ueyama T, Kasahara H, Ishiwata T, Nie Q, Izumo S
Mol Cell Biol. 2003
PubMed ID: 14645532
Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation.
Simon R, Lufkin T
Mol Cell Biol. 2003
PubMed ID: 14645517
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT
Proc Natl Acad Sci U S A. 2003
PubMed ID: 14610273
Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji SX, Shimazu K, Kimes N, Huelsken J, Birchmeier W, Lu B, Reichardt LF
Neuron. 2003
PubMed ID: 14622577
Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.
Uemura K, Kitagawa N, Kohno R, Kuzuya A, Kageyama T, Chonabayashi K, Shibasaki H, Shimohama S
J Neurosci Res. 2003
PubMed ID: 14515347
A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.
Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK
Cell. 2003
PubMed ID: 13678586
Expression of classical cadherins in thyroid development: maintenance of an epithelial phenotype throughout organogenesis.
Fagman H, Grände M, Edsbagge J, Semb H, Nilsson M
Endocrinology. 2003
PubMed ID: 12865344
Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study.
Chen YM, Lee NP, Mruk DD, Lee WM, Cheng CY
Biol Reprod. 2003
PubMed ID: 12700184
Beating is necessary for transdifferentiation of skeletal muscle-derived cells into cardiomyocytes.
Iijima Y, Nagai T, Mizukami M, Matsuura K, Ogura T, Wada H, Toko H, Akazawa H, Takano H, Nakaya H, Komuro I
FASEB J. 2003
PubMed ID: 12738802
N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.
Wahl JK, Kim YJ, Cullen JM, Johnson KR, Wheelock MJ
J Biol Chem. 2003
PubMed ID: 12604612
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI
Genes Dev. 2003
PubMed ID: 12695331
Comparative expression patterns of T-, N-, E-cadherins, beta-catenin, and polysialic acid neural cell adhesion molecule in rat cochlea during development: implications for the nature of Kölliker's organ.
Simonneau L, Gallego M, Pujol R
J Comp Neurol. 2003
PubMed ID: 12640664
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Luo Y, Radice GL
J Cell Sci. 2003
PubMed ID: 12640032
Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.
Tanaka Y, Nakanishi H, Kakunaga S, Okabe N, Kawakatsu T, Shimizu K, Takai Y
Mol Biol Cell. 2003
PubMed ID: 12686612
Rab8B GTPase and junction dynamics in the testis.
Lau AS, Mruk DD
Endocrinology. 2003
PubMed ID: 12639940
Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.
Kang JS, Feinleib JL, Knox S, Ketteringham MA, Krauss RS
Proc Natl Acad Sci U S A. 2003
PubMed ID: 12634428
Targeting of p0071 to desmosomes and adherens junctions is mediated by different protein domains.
Hatzfeld M, Green KJ, Sauter H
J Cell Sci. 2003
PubMed ID: 12615965
N-cadherin regulates ingrowth and laminar targeting of thalamocortical axons.
Poskanzer K, Needleman LA, Bozdagi O, Huntley GW
J Neurosci. 2003
PubMed ID: 12657688
RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.
Okabe T, Nakamura T, Nishimura YN, Kohu K, Ohwada S, Morishita Y, Akiyama T
J Biol Chem. 2003
PubMed ID: 12531901
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Lee NP, Mruk D, Lee WM, Cheng CY
Biol Reprod. 2003
PubMed ID: 12533412
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team
Proc Natl Acad Sci U S A. 2002
PubMed ID: 12477932
PTP1B modulates the association of beta-catenin with N-cadherin through binding to an adjacent and partially overlapping target site.
Xu G, Arregui C, Lilien J, Balsamo J
J Biol Chem. 2002
PubMed ID: 12377785
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team
Nature. 2002
PubMed ID: 12466851
N-cadherin upregulation and function in response of smooth muscle cells to arterial injury.
Jones M, Sabatini PJ, Lee FS, Bendeck MP, Langille BL
Arterioscler Thromb Vasc Biol. 2002
PubMed ID: 12482821
Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.
Taddei ML, Chiarugi P, Cirri P, Buricchi F, Fiaschi T, Giannoni E, Talini D, Cozzi G, Formigli L, Raugei G, Ramponi G
Cancer Res. 2002
PubMed ID: 12438242
A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor.
Suyama K, Shapiro I, Guttman M, Hazan RB
Cancer Cell. 2002
PubMed ID: 12398894
Differential regulation of cadherins and catenins during axonal reorganization in the adult rat CNS.
Fasen K, Beck H, Elger CE, Lie AA
J Neuropathol Exp Neurol. 2002
PubMed ID: 12387456
Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion.
Rhee J, Mahfooz NS, Arregui C, Lilien J, Balsamo J, VanBerkum MF
Nat Cell Biol. 2002
PubMed ID: 12360290
Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization.
Tran NL, Adams DG, Vaillancourt RR, Heimark RL
J Biol Chem. 2002
PubMed ID: 12095980
N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts.
Charrasse S, Meriane M, Comunale F, Blangy A, Gauthier-Rouvière C
J Cell Biol. 2002
PubMed ID: 12213839
Expression of adhesion and extracellular matrix molecules in the developing human brain.
Anlar B, Atilla P, Cakar AN, Kose MF, Beksaç MS, Dagdeviren A, Akçören Z
J Child Neurol. 2002
PubMed ID: 12503652
Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development.
Sinn HW, Balsamo J, Lilien J, Lin JJ
Dev Dyn. 2002
PubMed ID: 12203715
Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes.
Coussen F, Normand E, Marchal C, Costet P, Choquet D, Lambert M, Mège RM, Mulle C
J Neurosci. 2002
PubMed ID: 12151522
Neural (N-) cadherin, a synaptic adhesion molecule, is induced in hippocampal mossy fiber axonal sprouts by seizure.
Shan W, Yoshida M, Wu XR, Huntley GW, Colman DR
J Neurosci Res. 2002
PubMed ID: 12125071
Regulation of cadherin junctions during mouse submandibular gland development.
Menko AS, Zhang L, Schiano F, Kreidberg JA, Kukuruzinska MA
Dev Dyn. 2002
PubMed ID: 12112462
The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration.
Hollnagel A, Grund C, Franke WW, Arnold HH
Mol Cell Biol. 2002
PubMed ID: 12052883
Systematic analysis of E-, N- and P-cadherin expression in mouse eye development.
Xu L, Overbeek PA, Reneker LW
Exp Eye Res. 2002
PubMed ID: 12126948
E- and N-cadherin distribution in developing and functional human teeth under normal and pathological conditions.
Heymann R, About I, Lendahl U, Franquin JC, Obrink B, Mitsiadis TA
Am J Pathol. 2002
PubMed ID: 12057916
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice.
Zhang N, Norton CR, Gridley T
Genesis. 2002
PubMed ID: 12001066
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.
Laura RP, Witt AS, Held HA, Gerstner R, Deshayes K, Koehler MF, Kosik KS, Sidhu SS, Lasky LA
J Biol Chem. 2002
PubMed ID: 11821434
Genetic dissection of cadherin function during nephrogenesis.
Dahl U, Sjödin A, Larue L, Radice GL, Cajander S, Takeichi M, Kemler R, Semb H
Mol Cell Biol. 2002
PubMed ID: 11839813
Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses.
Izawa I, Nishizawa M, Ohtakara K, Inagaki M
J Biol Chem. 2002
PubMed ID: 11729199
Cadherin-mediated cell sorting not determined by binding or adhesion specificity.
Niessen CM, Gumbiner BM
J Cell Biol. 2002
PubMed ID: 11790800
Carbohydrate moieties of N-cadherin from human melanoma cell lines.
Ciołczyk-Wierzbicka D, Gil D, Hoja-Łukowicz D, Lityńska A, Laidler P
Acta Biochim Pol. 2002
PubMed ID: 12545205
Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis.
Fischer L, Boland G, Tuan RS
J Cell Biochem. 2002
PubMed ID: 11835406
TGFbeta2 in corneal morphogenesis during mouse embryonic development.
Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW
Dev Biol. 2001
PubMed ID: 11784073
Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.
Zhang JQ, Elzey B, Williams G, Lu S, Law DJ, Horowits R
Biochemistry. 2001
PubMed ID: 11732910
Dorsal pancreas agenesis in N-cadherin- deficient mice.
Esni F, Johansson BR, Radice GL, Semb H
Dev Biol. 2001
PubMed ID: 11784004
N-cadherin is involved in axon-oligodendrocyte contact and myelination.
Schnädelbach O, Ozen I, Blaschuk OW, Meyer RL, Fawcett JW
Mol Cell Neurosci. 2001
PubMed ID: 11414796
Creation of genome-wide protein expression libraries using random activation of gene expression.
Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M
Nat Biotechnol. 2001
PubMed ID: 11329013
Calcium-dependent adhesion is necessary for the maintenance of prosomeres.
McCarthy M, Na E, Neyt C, Langston A, Fishell G
Dev Biol. 2001
PubMed ID: 11319859
Structural abnormalities develop in the brain after ablation of the gene encoding nonmuscle myosin II-B heavy chain.
Tullio AN, Bridgman PC, Tresser NJ, Chan CC, Conti MA, Adelstein RS, Hara Y
J Comp Neurol. 2001
PubMed ID: 11283949
Essential tyrosine residues for interaction of the non-receptor protein-tyrosine phosphatase PTP1B with N-cadherin.
Rhee J, Lilien J, Balsamo J
J Biol Chem. 2001
PubMed ID: 11106648
A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens.
Thut CJ, Rountree RB, Hwa M, Kingsley DM
Dev Biol. 2001
PubMed ID: 11180952
Functional annotation of a full-length mouse cDNA collection.
Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schönbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature. 2001
PubMed ID: 11217851
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Luo Y, Ferreira-Cornwell M, Baldwin H, Kostetskii I, Lenox J, Lieberman M, Radice G
Development. 2001
PubMed ID: 11171330
Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.
Meigs TE, Fields TA, McKee DD, Casey PJ
Proc Natl Acad Sci U S A. 2001
PubMed ID: 11136230
N-cadherin and Cx43alpha1 gap junctions modulates mouse neural crest cell motility via distinct pathways.
Xu X, Li WE, Huang GY, Meyer R, Chen T, Luo Y, Thomas MP, Radice GL, Lo CW
Cell Commun Adhes. 2001
PubMed ID: 12064611
Dosage requirement and allelic expression of PAX6 during lens placode formation.
van Raamsdonk CD, Tilghman SM
Development. 2000
PubMed ID: 11076764
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y
Genome Res. 2000
PubMed ID: 11076861
The armadillo repeat region targets ARVCF to cadherin-based cellular junctions.
Kaufmann U, Zuppinger C, Waibler Z, Rudiger M, Urbich C, Martin B, Jockusch BM, Eppenberger H, Starzinski-Powitz A
J Cell Sci. 2000
PubMed ID: 11058098
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y
Genome Res. 2000
PubMed ID: 11042159
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.
Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, Rosenfeldt HM, Nava VE, Chae SS, Lee MJ, Liu CH, Hla T, Spiegel S, Proia RL
J Clin Invest. 2000
PubMed ID: 11032855
Wnt/frizzled-2 signaling induces aggregation and adhesion among cardiac myocytes by increased cadherin-beta-catenin complex.
Toyofuku T, Hong Z, Kuzuya T, Tada M, Hori M
J Cell Biol. 2000
PubMed ID: 10893270
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.
Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG
Nat Neurosci. 2000
PubMed ID: 10862698
Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase.
Kwon YT, Gupta A, Zhou Y, Nikolic M, Tsai LH
Curr Biol. 2000
PubMed ID: 10753743
Functional cis-heterodimers of N- and R-cadherins.
Shan WS, Tanaka H, Phillips GR, Arndt K, Yoshida M, Colman DR, Shapiro L
J Cell Biol. 2000
PubMed ID: 10662782
Multiple cadherin superfamily members with unique expression profiles are produced in rat testis.
Johnson KJ, Patel SR, Boekelheide K
Endocrinology. 2000
PubMed ID: 10650949
Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis.
Reneker LW, Silversides DW, Xu L, Overbeek PA
Development. 2000
PubMed ID: 10631174
Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines.
Laidler P, Gil D, Pituch-Noworolska A, Ciołczyk D, Ksiazek D, Przybyło M, Lityńska A
Acta Biochim Pol. 2000
PubMed ID: 11996105
Follicular atresia and luteolysis. Evidence of a role for N-cadherin.
Makrigiannakis A, Coukos G, Blaschuk O, Coutifaris C
Ann N Y Acad Sci. 2000
PubMed ID: 10818391
Adhesive subdivisions intrinsic to the epithelial somites.
Horikawa K, Radice G, Takeichi M, Chisaka O
Dev Biol. 1999
PubMed ID: 10545229
The generation and in vivo differentiation of murine embryonal stem cells genetically null for either N-cadherin or N- and P-cadherin.
Moore R, Radice GL, Dominis M, Kemler R
Int J Dev Biol. 1999
PubMed ID: 10707907
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.
Carmeliet P, Lampugnani MG, Moons L, Breviario F, Compernolle V, Bono F, Balconi G, Spagnuolo R, Oostuyse B, Dewerchin M, Zanetti A, Angellilo A, Mattot V, Nuyens D, Lutgens E, Clotman F, de Ruiter MC, Gittenberger-de Groot A, Poelmann R, Lupu F, Herbert JM, Collen D, Dejana E
Cell. 1999
PubMed ID: 10428027
Cadherins and tissue formation: integrating adhesion and signaling.
Vleminckx K, Kemler R
Bioessays. 1999
PubMed ID: 10333730
Requirement of a novel gene, Xin, in cardiac morphogenesis.
Wang DZ, Reiter RS, Lin JL, Wang Q, Williams HS, Krob SL, Schultheiss TM, Evans S, Lin JJ
Development. 1999
PubMed ID: 10021346
The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development.
Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S
Development. 1999
PubMed ID: 10021345
delta-catenin, an adhesive junction-associated protein which promotes cell scattering.
Lu Q, Paredes M, Medina M, Zhou J, Cavallo R, Peifer M, Orecchio L, Kosik KS
J Cell Biol. 1999
PubMed ID: 9971746
High-efficiency full-length cDNA cloning.
Carninci P, Hayashizaki Y
Methods Enzymol. 1999
PubMed ID: 10349636
Structure-function analysis of cell adhesion by neural (N-) cadherin.
Tamura K, Shan WS, Hendrickson WA, Colman DR, Shapiro L
Neuron. 1998
PubMed ID: 9655503
Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.
Kremmidiotis G, Baker E, Crawford J, Eyre HJ, Nahmias J, Callen DF
Genomics. 1998
PubMed ID: 9615235
Rat testicular N-cadherin: its complementary deoxyribonucleic acid cloning and regulation.
Chung SS, Mo MY, Silvestrini B, Lee WM, Cheng CY
Endocrinology. 1998
PubMed ID: 9528971
Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization.
Navarro P, Ruco L, Dejana E
J Cell Biol. 1998
PubMed ID: 9508779
The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis.
Gad JM, Keeling SL, Wilks AF, Tan SS, Cooper HM
Dev Biol. 1997
PubMed ID: 9441666
Expression of cadherin-8 mRNA in the developing mouse central nervous system.
Korematsu K, Redies C
J Comp Neurol. 1997
PubMed ID: 9336230
Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain.
Stoykova A, Götz M, Gruss P, Price J
Development. 1997
PubMed ID: 9367432
Fusion competence of myoblasts rendered genetically null for N-cadherin in culture.
Charlton CA, Mohler WA, Radice GL, Hynes RO, Blau HM
J Cell Biol. 1997
PubMed ID: 9230075
Multiple cadherins are expressed in human fibroblasts.
Matsuyoshi N, Imamura S
Biochem Biophys Res Commun. 1997
PubMed ID: 9199196
N-cadherin protein distribution in normal embryos and in embryos carrying mutations in the homeobox gene Hoxa-4.
Packer AI, Elwell VA, Parnass JD, Knudsen KA, Wolgemuth DJ
Int J Dev Biol. 1997
PubMed ID: 9240562
Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion.
Ali J, Liao F, Martens E, Muller WA
Microcirculation. 1997
PubMed ID: 9219219
Interaction of the adaptor protein Shc and the adhesion molecule cadherin.
Xu Y, Guo DF, Davidson M, Inagami T, Carpenter G
J Biol Chem. 1997
PubMed ID: 9153187
The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.
Miner JH, Patton BL, Lentz SI, Gilbert DJ, Snider WD, Jenkins NA, Copeland NG, Sanes JR
J Cell Biol. 1997
PubMed ID: 9151674
Cloning and chromosomal localization of mouse aquaporin 4: exclusion of a candidate mutant phenotype, ataxia.
Turtzo LC, Lee MD, Lu M, Smith BL, Copeland NG, Gilbert DJ, Jenkins NA, Agre P
Genomics. 1997
PubMed ID: 9143504
Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology.
Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH
Biochem Mol Med. 1997
PubMed ID: 9169087
Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins.
Liao X, Du Y, Morse HC, Jenkins NA, Copeland NG
Oncogene. 1997
PubMed ID: 9070650
Developmental defects in mouse embryos lacking N-cadherin.
Radice GL, Rayburn H, Matsunami H, Knudsen KA, Takeichi M, Hynes RO
Dev Biol. 1997
PubMed ID: 9015265
The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.
Uchida N, Honjo Y, Johnson KR, Wheelock MJ, Takeichi M
J Cell Biol. 1996
PubMed ID: 8909549
A role for cadherins in tissue formation.
Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, Kemler R
Development. 1996
PubMed ID: 8898231
A comprehensive survey of the cadherins expressed in the testes of fetal, immature, and adult mice utilizing the polymerase chain reaction.
Munro SB, Blaschuk OW
Biol Reprod. 1996
PubMed ID: 8879495
The Cdc25 genes map to mouse chromosomes 2, 9, and 18.
Lock LF, Wickramasinghe D, Ernst MK, Gilbert DJ, Copeland NG, Jenkins NA, Donovan PJ
Mamm Genome. 1996
PubMed ID: 8854867
Localization of the homolog of a mouse craniofacial mutant to human chromosome 18q11 and evaluation of linkage to human CLP and CPO.
Griffith AJ, Burgess DL, Kohrman DC, Yu J, Blaschak J, Blanton SH, Boehnke M, Hecht JT, Overhauser J, Meisler MH
Genomics. 1996
PubMed ID: 8786128
Location of the 9257 and ataxia mutations on mouse chromosome 18.
Griffith AJ, Radice GL, Burgess DL, Kohrman DC, Hansen GM, Justice MJ, Johnson KR, Davisson MT, Meisler MH
Mamm Genome. 1996
PubMed ID: 8662222
A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.
Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J
J Biol Chem. 1996
PubMed ID: 8626800
Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.
Breier G, Breviario F, Caveda L, Berthier R, Schnürch H, Gotsch U, Vestweber D, Risau W, Dejana E
Blood. 1996
PubMed ID: 8555485
Changing patterns of cell adhesion molecules during mouse pelage hair follicle development. 2. Follicle morphogenesis in the hair mutants, Tabby and downy.
Vielkind U, Hardy MH
Acta Anat (Basel). 1996
PubMed ID: 9226037
Changing patterns of cell adhesion molecules during mouse pelage hair follicle development. 1. Follicle morphogenesis in wild-type mice.
Hardy MH, Vielkind U
Acta Anat (Basel). 1996
PubMed ID: 9226036
Shared cell adhesion molecule (CAM) homology domains point to CAMs signalling via FGF receptors.
Doherty P, Smith P, Walsh FS
Perspect Dev Neurobiol. 1996
PubMed ID: 9168198
N-cadherin in adult rat cardiomyocytes in culture. II. Spatio-temporal appearance of proteins involved in cell-cell contact and communication. Formation of two distinct N-cadherin/catenin complexes.
Hertig CM, Butz S, Koch S, Eppenberger-Eberhardt M, Kemler R, Eppenberger HM
J Cell Sci. 1996
PubMed ID: 8834786
Seven genes from human chromosome 18 map to chromosome 24 in the bovine.
Larsen NJ, Womack JE, Kirkpatrick BW
Cytogenet Cell Genet. 1996
PubMed ID: 8697804
Fetal brain subdivisions defined by R- and E-cadherin expressions: evidence for the role of cadherin activity in region-specific, cell-cell adhesion.
Matsunami H, Takeichi M
Dev Biol. 1995
PubMed ID: 8612964
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin.
Hermiston ML, Gordon JI
Science. 1995
PubMed ID: 7502046
Expression of catenins during mouse embryonic development and in adult tissues.
Butz S, Larue L
Cell Adhes Commun. 1995
PubMed ID: 8821035
Cadherin expression in the developing vertebrate CNS: from neuromeres to brain nuclei and neural circuits.
Redies C
Exp Cell Res. 1995
PubMed ID: 7556431
Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin.
Sacco PA, McGranahan TM, Wheelock MJ, Johnson KR
J Biol Chem. 1995
PubMed ID: 7650039
Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.
Kimura Y, Matsunami H, Inoue T, Shimamura K, Uchida N, Ueno T, Miyazaki T, Takeichi M
Dev Biol. 1995
PubMed ID: 7750650
Cloning and expression analysis of a novel mesodermally expressed cadherin.
Hoffmann I, Balling R
Dev Biol. 1995
PubMed ID: 7750649
Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain.
Whitesides JG, LaMantia AS
Dev Biol. 1995
PubMed ID: 7750641
Expressed cadherin pseudogenes are localized to the critical region of the spinal muscular atrophy gene.
Selig S, Bruno S, Scharf JM, Wang CH, Vitale E, Gilliam TC, Kunkel LM
Proc Natl Acad Sci U S A. 1995
PubMed ID: 7731968
In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death.
Hermiston ML, Gordon JI
J Cell Biol. 1995
PubMed ID: 7721948
Structural basis of cell-cell adhesion by cadherins.
Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grübel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA
Nature. 1995
PubMed ID: 7885471
Estradiol regulates N-cadherin mRNA levels in the mouse ovary.
MacCalman CD, Farookhi R, Blaschuk OW
Dev Genet. 1995
PubMed ID: 7758243
Altered gene expression in murine branchial arches following in utero exposure to retinoic acid.
Taylor LE, Bennett GD, Finnell RH
J Craniofac Genet Dev Biol. 1995
PubMed ID: 7601910
cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen.
Ishikawa H, Silos SA, Tamai K, Copeland NG, Gilbert DJ, Jenkins NA, Uitto J
Mamm Genome. 1994
PubMed ID: 7894164
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Hülsken J, Birchmeier W, Behrens J
J Cell Biol. 1994
PubMed ID: 7806582
Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation.
Shibata T, Gotoh M, Ochiai A, Hirohashi S
Biochem Biophys Res Commun. 1994
PubMed ID: 8074697
Expression and localization of N- and E-cadherin in the human testis and epididymis.
Andersson AM, Edvardsen K, Skakkebaek NE
Int J Androl. 1994
PubMed ID: 7995652
Structure of the human N-cadherin gene: YAC analysis and fine chromosomal mapping to 18q11.2.
Wallis J, Fox MF, Walsh FS
Genomics. 1994
PubMed ID: 7959764
Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18.
Buxton RS, Wheeler GN, Pidsley SC, Marsden MD, Adams MJ, Jenkins NA, Gilbert DJ, Copeland NG
Genomics. 1994
PubMed ID: 7959727
Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas.
Justice MJ, Morse HC, Jenkins NA, Copeland NG
J Virol. 1994
PubMed ID: 8107195
Isolation and developmental expression of retinoic-acid-induced genes.
Jonk LJ, de Jonge ME, Vervaart JM, Wissink S, Kruijer W
Dev Biol. 1994
PubMed ID: 8314004
Cloning, expression, and chromosomal localization of the mouse meprin beta subunit.
Gorbea CM, Marchand P, Jiang W, Copeland NG, Gilbert DJ, Jenkins NA, Bond JS
J Biol Chem. 1993
PubMed ID: 8407940
Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene.
Matsunami H, Miyatani S, Inoue T, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M
J Cell Sci. 1993
PubMed ID: 8270638
Expression of N-cadherin mRNA during development of the mouse brain.
Redies C, Takeichi M
Dev Dyn. 1993
PubMed ID: 8400409
The cell adhesion molecule M-cadherin is specifically expressed in developing and regenerating, but not denervated skeletal muscle.
Moore R, Walsh FS
Development. 1993
PubMed ID: 8404540
The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species.
Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A
Genomics. 1992
PubMed ID: 1427864
Genomic structure and chromosomal mapping of the mouse N-cadherin gene.
Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M
Proc Natl Acad Sci U S A. 1992
PubMed ID: 1528849
E-cadherin expression in a particular subset of sensory neurons.
Shimamura K, Takahashi T, Takeichi M
Dev Biol. 1992
PubMed ID: 1644219
Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin.
Knudsen KA, Wheelock MJ
J Cell Biol. 1992
PubMed ID: 1639850
Extrajunctional distribution of N-cadherin in cultured human endothelial cells.
Salomon D, Ayalon O, Patel-King R, Hynes RO, Geiger B
J Cell Sci. 1992
PubMed ID: 1500442
Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.
Suzuki S, Sano K, Tanihara H
Cell Regul. 1991
PubMed ID: 2059658
Human N-cadherin: nucleotide and deduced amino acid sequence.
Reid RA, Hemperly JJ
Nucleic Acids Res. 1990
PubMed ID: 2216790
N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.
Walsh FS, Barton CH, Putt W, Moore SE, Kelsell D, Spurr N, Goodfellow PN
J Neurochem. 1990
PubMed ID: 2384753
A positional marker for the dorsal embryonic retina is homologous to the high-affinity laminin receptor.
Rabacchi SA, Neve RL, Dräger UC
Development. 1990
PubMed ID: 2144817
Neural cadherin: role in selective cell-cell adhesion.
Miyatani S, Shimamura K, Hatta M, Nagafuchi A, Nose A, Matsunaga M, Hatta K, Takeichi M
Science. 1989
PubMed ID: 2762814

Model Organism Phenotype Links from MGI Top Help

Model Organism Phenotype Links

External Links Top Help

	Human	Mouse	Rat
Entrez Gene	1000	12558	83501
EnsEMBL Gene(s)	ENSG00000170558	ENSMUSG00000024304	ENSRNOG00000015602
Unigene	Hs.464829	Mm.257437	Rn.23200
Homologene	CDH2	Cdh2	Cdh2
OMIM	114020	N/A	N/A
GeneCards	CDH2	N/A	N/A
Beta Cell Genomics	DT.414612	DT.87072440 DT.94248587 DT.94299836	N/A
Reactome	P19022	N/A	N/A
Plasma Peptide Atlas	ENSP00000269141	N/A	N/A
WikiGenes	1000	12558	83501

External resources from NIDDK Consortium Interconnectivity Network Top Help

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Interactor	Interactor	Sources	Classification	Pubmed IDs
CDH2	CDH4	HPRD, BioGRID	empirical	10662782
CDH2	CDH11	HPRD, BioGRID	empirical	14625392
CDH2	EXOC5	IntAct	empirical	21988832
CDH2	GNA13	HPRD, BioGRID	empirical	11136230
CDH2	CREBBP	HPRD	empirical	13678586
CDH2	CTNNA1	HPRD, BioGRID, Reactome	empirical	12604612 14625392 7806582
CDH2	CTNNA2	Reactome	predicted
CDH2	CTNNB1	HPRD, MINT, IntAct, BioGRID, Reactome	empirical	12151522 12604612 17057644 21357690 14625392 11835406 12695331 15834408
CDH2	CTNND1	IntAct, BioGRID, Reactome	empirical	21357690 14625392 12604612 15834408 20371349 7806582
CDH2	CTNND2	HPRD, MIPS	empirical	9971746
CDH2	FGFR4	HPRD	empirical	9168198
CDH2	KIFAP3	BioGRID	empirical	15834408
CDH2	NPHP4	IntAct	empirical	21565611
CDH2	PTPN22	IntAct	empirical	19167335
CDH2	GNA12	HPRD, BioGRID	empirical	11136230
CDH2	GRIK2	HPRD	empirical	12151522
CDH2	GRIN1	HPRD, IntAct	empirical	10862698 16635246
CDH2	GRIN2B	IntAct	empirical	16635246
CDH2	GRIN2D	HPRD	empirical	10862698
CDH2	JUP	HPRD, BioGRID, Reactome	empirical	1639850 12604612 8074697 14625392 7650039 7806582
CDH2	PTPRQ	BioGRID	empirical	16973135
CDH2	KIF5C	BioGRID	empirical	15834408
CDH2	LRP6	BioGRID	empirical	19075000
CDH2	ARVCF	HPRD	empirical	11058098
CDH2	CDON	HPRD, BioGRID	empirical	12634428
CDH2	RAB8B	BioGRID	empirical	12639940
CDH2	PIK3R1	HPRD	empirical	15192701
CDH2	PRKAR1A	IntAct	empirical	20195357
CDH2	LRRC7	HPRD, BioGRID	empirical	11729199
CDH2	PTPN1	HPRD, MINT, IntAct	empirical	12377785 11106648
CDH2	PTPN6	IntAct	empirical	19167335
CDH2	PTPN7	IntAct	empirical	19167335
CDH2	PTPN12	IntAct	empirical	19167335
CDH2	PTPRB	IntAct	empirical	19167335
CDH2	PTPRC	IntAct	empirical	19167335
CDH2	PTPRG	IntAct	empirical	19167335
CDH2	PTPRJ	IntAct	empirical	19167335
CDH2	PTPRK	IntAct	empirical	19167335
CDH2	ACTA1	BioGRID	empirical	12438242
CDH2	PTPRO	IntAct	empirical	19167335
CDH2	PTPRR	IntAct	empirical	19167335
CDH2	RET	IntAct	empirical	21357690
CDH2	RYK	BioGRID	empirical	21875946
CDH2	UBC	BioGRID	empirical	21139048 21890473
CDH2	YWHAB	IntAct	empirical	16635246
CDH2	YWHAZ	IntAct	empirical	19562802
CDH2	AXIN1	BioGRID	empirical	19075000
CDH2	PKP4	BioGRID	empirical	12615965
CDH2	WNT3A	BioGRID	empirical	19075000
CDH2	BOC	HPRD, BioGRID	empirical	12634428
CDH2	KIF3B	BioGRID	empirical	15834408
CDH2	ARHGAP32	HPRD, BioGRID	empirical	12531901