T1DBase - Home Page

T1DBase focuses on two research areas in type 1 diabetes (T1D): the genetics of T1D susceptibility and beta cell biology. This site provides tools which allow scientists to analyze, store, and share this T1D data with other scientists. (More)

T1DBase News

Mon, 1 Sep 2008 10:42:17 GMT

WTCCC minor allele frequency data removed

Due to privacy concerns MAF data for WTCCC has been removed from the site. Access to this data can be requested through the Wellcome Trust

Tue, 19 Aug 2008 12:19:06 GMT

Updated Protein Models

The protein annotations for T1DBase curated transcripts have been updated on the GeneOverview pages and a new GBrowse datasource has been included to look at the proteins more in depth.

Mon, 18 Aug 2008 17:08:22 GMT

BLAT tool updated

Perform a sequence based search across T1D susceptibility regions for Human and Mouse.

T1DBase Journals of Interest

Wed, 20 Aug 2008 13:17:21 GMT

Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to ...

Serreze DV et al; J. Immunol. 2008 Mar 1; 180(5)

Wed, 20 Aug 2008 13:17:21 GMT

Differential allelic expression in the human genome: a robust approach to identify genetic and ep...

Serre D et al; PLoS Genet. 2008 Feb; 4(2)

Wed, 20 Aug 2008 13:17:21 GMT

Genome-wide association studies for complex traits: consensus, uncertainty and challenges.

McCarthy MI et al; Nat. Rev. Genet. 2008 May; 9(5)

Beta Cell Gene Bank

Mon, 2 Jun 2008 13:08:10 GMT

TCF7L2

Transcription factor 7-like 2 gene (TCF7L2, T-cell factor 7-like 2; formerly TCF4) is a high mobility group (HMG) box containing...

Mon, 2 Jun 2008 13:35:35 GMT

GPR119

GPR119 is a G protein-coupled receptor expressed predominantly in the human and rodent pancreas, in gastrointestinal tract and in rodent brain. This...

Tue, 15 Apr 2008 00:55:35 GMT

iNOS

The enzyme inducible nitric oxide synthase (iNOS) catalyzes the conversion of L-arginine to citrulline and produces nitric oxide (NO). Citrulline...